John Sinard, MD, PhD
Research & Publications
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Research Summary
I am interested in the use of computers and information technology to promote the practice and teaching of anatomic pathology. Current work includes developing enhancements to our department's clinical information system(s) to improve workflow in the department.
Specialized Terms: Medical informatics
Extensive Research Description
My current academic interests are in the fields of pathology informatics and practice management, including quality assurance and patient safety. The computer has long been a tool for data storage and management. More recently, information systems have become integrated into the daily practice of pathology, providing not only access to data, but also directing workflow, managing resources, and helping to guide medical decisions. Proper design of these systems is crucial to their being a useful adjunct to patient care rather than an obstacle which has to be overcome. Such design requires a comprehensive understanding of the clinical workflow as well as the capabilities and limitations of the information systems. In many cases, custom software development provides the greatest gain in workflow optimization, clinician productivity and efficiency, and patient safety. Proper capture and storage of data can also enable subsequent workflow analysis and quality tracking.
Coauthors
Research Interests
Ophthalmology; Pathology; Informatics
Selected Publications
- Proceedings of the Association for Pathology Informatics Bootcamp 2022Obstfeld A, Brodsky V, Carter A, Gershkovich P, Haymond S, Levy B, Sinard J, Sellers D, Stoffel M, Jackups R. Proceedings of the Association for Pathology Informatics Bootcamp 2022. Journal Of Pathology Informatics 2023, 14: 100331. PMID: 37705688, PMCID: PMC10495674, DOI: 10.1016/j.jpi.2023.100331.
- Chronic Lymphocytic Leukemia Presenting as Bilateral Periorbital Edema Treated With Low-dose Radiation TherapySpadaro J, Chow R, Sinard J, Watsky K, Habib L. Chronic Lymphocytic Leukemia Presenting as Bilateral Periorbital Edema Treated With Low-dose Radiation Therapy. Ophthalmic Plastic And Reconstructive Surgery 2023, 39: e78-e81. PMID: 36852835, DOI: 10.1097/iop.0000000000002338.
- NK/T-cell Lymphoma With Orbital Involvement: A Case Report and Systematic Review of the LiteratureDhodapkar R, Spadaro J, Heng J, Sinard J, Lee Y, Habib L, Pointdujour-Lim R. NK/T-cell Lymphoma With Orbital Involvement: A Case Report and Systematic Review of the Literature. Ophthalmic Plastic And Reconstructive Surgery 2023, 39: 316-327. PMID: 36692957, DOI: 10.1097/iop.0000000000002317.
- Systems approach to enhance Lynch syndrome diagnosis through tumour testingSingh V, Mezzacappa C, Gershkovich P, Di Giovanna J, Ganzak A, Gibson J, Sinard J, Xicola RM, Llor X. Systems approach to enhance Lynch syndrome diagnosis through tumour testing. Journal Of Medical Genetics 2022, 60: 533-539. PMID: 36115663, PMCID: PMC10020126, DOI: 10.1136/jmg-2022-108770.
- Bilateral dacryoadenitis as the initial presentation of ANCA-associated vasculitis in a pediatric patientSpadaro JZ, Sinard J, Habib L. Bilateral dacryoadenitis as the initial presentation of ANCA-associated vasculitis in a pediatric patient. Orbit 2022, 43: 231-235. PMID: 35801829, DOI: 10.1080/01676830.2022.2093920.
- Local recurrence of uveal melanoma and concomitant brain metastases associated with an activating telomerase promoter mutation seven years after secondary enucleationHeng JS, Perzia BM, Sinard JH, Pointdujour-Lim R. Local recurrence of uveal melanoma and concomitant brain metastases associated with an activating telomerase promoter mutation seven years after secondary enucleation. American Journal Of Ophthalmology Case Reports 2022, 27: 101607. PMID: 35707052, PMCID: PMC9189986, DOI: 10.1016/j.ajoc.2022.101607.
- Primary Mesenchymal Tumors of the Thyroid Gland: A Modern Retrospective Cohort Including the First Case of TFE3-Translocated Malignant Perivascular Epithelioid Cell Tumor (PEComa)Zhang L, Lubin D, Sinard JH, Dickson BC, Antonescu CR, Wu H, Panni RZ, Dogan S, Untch BR, Ghossein RA, Xu B. Primary Mesenchymal Tumors of the Thyroid Gland: A Modern Retrospective Cohort Including the First Case of TFE3-Translocated Malignant Perivascular Epithelioid Cell Tumor (PEComa). Head And Neck Pathology 2022, 16: 716-727. PMID: 35218514, PMCID: PMC9424363, DOI: 10.1007/s12105-022-01428-7.
- Necrotic Uveal Melanoma Mimics Orbital Cellulitis: A ReviewAbdel-Aty A, Linderman WL, Kombo N, Sinard J, Pointdujour-Lim R. Necrotic Uveal Melanoma Mimics Orbital Cellulitis: A Review. Ocular Oncology And Pathology 2021, 8: 1-8. PMID: 35356597, PMCID: PMC8914239, DOI: 10.1159/000515558.
- Cilioretinal Artery Occlusion as the Presenting Manifestation of Left Atrial MyxomaMir T, Megalla M, Sinard J, Wang J. Cilioretinal Artery Occlusion as the Presenting Manifestation of Left Atrial Myxoma. Journal Of VitreoRetinal Diseases 2021, 6: 320-323. PMID: 37007931, PMCID: PMC9976024, DOI: 10.1177/24741264211034114.
- An independent assessment of an artificial intelligence system for prostate cancer detection shows strong diagnostic accuracyPerincheri S, Levi AW, Celli R, Gershkovich P, Rimm D, Morrow JS, Rothrock B, Raciti P, Klimstra D, Sinard J. An independent assessment of an artificial intelligence system for prostate cancer detection shows strong diagnostic accuracy. Modern Pathology 2021, 34: 1588-1595. PMID: 33782551, PMCID: PMC8295034, DOI: 10.1038/s41379-021-00794-x.
- Measuring Faculty Effort: A Quantitative Approach That Aligns Personal and Institutional Goals in Pathology at YaleMorrow JS, Gershkovich P, Gibson J, Gilshannon M, Kowalski D, Levi AW, Nguyen DX, Rimm DL, Xu ML, Sinard J. Measuring Faculty Effort: A Quantitative Approach That Aligns Personal and Institutional Goals in Pathology at Yale. Academic Pathology 2021, 8: 23742895211047985. PMID: 34646939, PMCID: PMC8504692, DOI: 10.1177/23742895211047985.
- Protecting the Pathology Commons in the Digital EraMazer BL, Paulson N, Sinard JH. Protecting the Pathology Commons in the Digital Era. Archives Of Pathology & Laboratory Medicine 2020, 144: 1037-1040. PMID: 32579394, DOI: 10.5858/arpa.2020-0022-ed.
- Histopathologic changes in cadaver eyes after MicroPulse and continuous wave transscleral cyclophotocoagulationMaslin JS, Chen PP, Sinard J, Nguyen AT, Noecker R. Histopathologic changes in cadaver eyes after MicroPulse and continuous wave transscleral cyclophotocoagulation. Canadian Journal Of Ophthalmology 2020, 55: 330-335. PMID: 32446502, DOI: 10.1016/j.jcjo.2020.03.010.
- Pulmonary Adenocarcinoma Metastatic to Periocular Skin and Orbital Tissue Presenting as Orbital Cellulitis.Li E, Sinard J, Sohrab M. Pulmonary Adenocarcinoma Metastatic to Periocular Skin and Orbital Tissue Presenting as Orbital Cellulitis. Ophthalmic Plastic And Reconstructive Surgery 2020, 36: e28-e30. PMID: 31789787, DOI: 10.1097/iop.0000000000001534.
- An Analysis of the Effect of the COVID-19 Pandemic on Case Volumes in an Academic Subspecialty-Based Anatomic Pathology PracticeSinard JH. An Analysis of the Effect of the COVID-19 Pandemic on Case Volumes in an Academic Subspecialty-Based Anatomic Pathology Practice. Academic Pathology 2020, 7: 2374289520959788. PMID: 33088911, PMCID: PMC7545513, DOI: 10.1177/2374289520959788.
- A Survey of LOINC Code Selection Practices Among Participants of the College of American Pathologists Coagulation (CGL) and Cardiac Markers (CRT) Proficiency Testing ProgramsStram M, Seheult J, Sinard JH, Campbell WS, Carter AB, de Baca ME, Quinn AM, Luu HS, Pathologists O. A Survey of LOINC Code Selection Practices Among Participants of the College of American Pathologists Coagulation (CGL) and Cardiac Markers (CRT) Proficiency Testing Programs. Archives Of Pathology & Laboratory Medicine 2019, 144: 586-596. PMID: 31603714, DOI: 10.5858/arpa.2019-0276-oa.
- A Semiquantitative Scoring System May Allow Biopsy Diagnosis of Pulmonary Large Cell Neuroendocrine CarcinomaBaine MK, Sinard JH, Cai G, Homer RJ. A Semiquantitative Scoring System May Allow Biopsy Diagnosis of Pulmonary Large Cell Neuroendocrine Carcinoma. American Journal Of Clinical Pathology 2019, 153: 165-174. PMID: 31593583, PMCID: PMC7571487, DOI: 10.1093/ajcp/aqz149.
- Dabrafenib and Trametinib for BRAF-Mutated Conjunctival MelanomaKim JM, Weiss S, Sinard JH, Pointdujour-Lim R. Dabrafenib and Trametinib for BRAF-Mutated Conjunctival Melanoma. Ocular Oncology And Pathology 2019, 6: 35-38. PMID: 32002403, PMCID: PMC6984155, DOI: 10.1159/000497473.
- Angiolymphoid Hyperplasia with Eosinophilia with Clinical Presentation Concerning for Juvenile Temporal ArteritisLi E, Sinard J, Distefano A, Sohrab M. Angiolymphoid Hyperplasia with Eosinophilia with Clinical Presentation Concerning for Juvenile Temporal Arteritis. Ocular Oncology And Pathology 2019, 6: 25-30. PMID: 32002401, PMCID: PMC6984143, DOI: 10.1159/000500361.
- Immune Checkpoint Inhibitor–Associated PericarditisAltan M, Toki MI, Gettinger SN, Carvajal-Hausdorf DE, Zugazagoitia J, Sinard JH, Herbst RS, Rimm DL. Immune Checkpoint Inhibitor–Associated Pericarditis. Journal Of Thoracic Oncology 2019, 14: 1102-1108. PMID: 30851443, PMCID: PMC6617516, DOI: 10.1016/j.jtho.2019.02.026.
- Pleomorphic lipoma of the bulbar conjunctivaLi E, Silbert J, Sinard J. Pleomorphic lipoma of the bulbar conjunctiva. BMJ Case Reports 2018, 11: e226548. PMID: 30567236, PMCID: PMC6301450, DOI: 10.1136/bcr-2018-226548.
- Epithelial–Myoepithelial Carcinoma Presenting as a Pseudo Veno-Lymphatic MalformationLi E, Distefano A, Sinard J, Wong A, Pointdujour-Lim R. Epithelial–Myoepithelial Carcinoma Presenting as a Pseudo Veno-Lymphatic Malformation. Ophthalmic Plastic And Reconstructive Surgery 2018, 34: e157-e160. PMID: 30080758, DOI: 10.1097/iop.0000000000001179.
- Orbital cellulitis with choroidal detachment following strabismus surgery in an adultKim JM, Megalla M, Howard M, Sinard J, Pointdujour-Lim R. Orbital cellulitis with choroidal detachment following strabismus surgery in an adult. Journal Of American Association For Pediatric Ophthalmology And Strabismus 2018, 22: 477-480. PMID: 30171895, DOI: 10.1016/j.jaapos.2018.04.016.
- Optimal Intraoperative Assessment of Gastric MarginsCelli R, Barbieri AL, Colunga M, Sinard J, Gibson JA. Optimal Intraoperative Assessment of Gastric Margins. American Journal Of Clinical Pathology 2018, 150: 353-363. PMID: 30020407, DOI: 10.1093/ajcp/aqy062.
- Bilateral Cicatrizing Conjunctivitis in a Middle-aged ManApostolopoulos N, Sinard J, Kombo N. Bilateral Cicatrizing Conjunctivitis in a Middle-aged Man. JAMA Ophthalmology 2018, 136: 706-707. PMID: 29596593, DOI: 10.1001/jamaophthalmol.2017.5490.
- A Semi-Quantitative Approach to Biopsy Diagnosis of Large Cell Neuroendocrine Carcinoma of the LungBaine M, Sinard J, Cai G, Homer R. A Semi-Quantitative Approach to Biopsy Diagnosis of Large Cell Neuroendocrine Carcinoma of the Lung. Journal Of Thoracic Oncology 2017, 12: s1543. DOI: 10.1016/j.jtho.2017.06.051.
- Acute Presentation of Mesectodermal Leiomyoma of the Ciliary BodyKim JM, Hall LB, Elia M, Ehrlich MS, Materin MA, Sinard JH. Acute Presentation of Mesectodermal Leiomyoma of the Ciliary Body. Ocular Oncology And Pathology 2017, 3: 304-309. PMID: 29344486, PMCID: PMC5757584, DOI: 10.1159/000464466.
- Asymmetric Deep Stromal Keratopathy in a Patient With Multiple MyelomaTainsh LT, Coady PA, Sinard JH, Neparidze N, Meskin SW, Adelman RA, Chow J. Asymmetric Deep Stromal Keratopathy in a Patient With Multiple Myeloma. Cornea 2017, 36: 372-374. PMID: 28079685, DOI: 10.1097/ico.0000000000001139.
- Repeat Conjunctival Biopsy after Immunomodulatory Therapy for Ocular Mucous Membrane PemphigoidGaudio PA, Sinard J, Shield DR, Huang JJ, King BA. Repeat Conjunctival Biopsy after Immunomodulatory Therapy for Ocular Mucous Membrane Pemphigoid. Ocular Immunology And Inflammation 2016, 26: 70-73. PMID: 27437791, DOI: 10.1080/09273948.2016.1194435.
- Pathology Informatics Essentials for Residents: A Flexible Informatics Curriculum Linked to Accreditation Council for Graduate Medical Education MilestonesHenricks WH, Karcher DS, Harrison JH, Sinard JH, Riben MW, Boyer PJ, Plath S, Thompson A, Pantanowitz L. Pathology Informatics Essentials for Residents: A Flexible Informatics Curriculum Linked to Accreditation Council for Graduate Medical Education Milestones. Archives Of Pathology & Laboratory Medicine 2016, 141: 113-124. PMID: 27383543, DOI: 10.5858/arpa.2016-0199-oa.
- Pathology Informatics Essentials for Residents: A flexible informatics curriculum linked to Accreditation Council for Graduate Medical Education milestonesHenricks WH, Karcher DS, Harrison JH, Sinard JH, Riben MW, Boyer PJ, Plath S, Thompson A, Pantanowitz L. Pathology Informatics Essentials for Residents: A flexible informatics curriculum linked to Accreditation Council for Graduate Medical Education milestones. Journal Of Pathology Informatics 2016, 7: 27. PMID: 27563486, PMCID: PMC4977974, DOI: 10.4103/2153-3539.185673.
- Pathology Informatics Essentials for ResidentsHenricks WH, Karcher DS, Harrison JH, Sinard JH, Riben MW, Boyer PJ, Plath S, Thompson A, Pantanowitz L. Pathology Informatics Essentials for Residents. Academic Pathology 2016, 3: 2374289516659051. PMID: 28725772, PMCID: PMC5497905, DOI: 10.1177/2374289516659051.
- Customizing Laboratory Information SystemsGershkovich P, Sinard JH. Customizing Laboratory Information Systems. Advances In Anatomic Pathology 2015, 22: 323-330. PMID: 26262515, DOI: 10.1097/pap.0000000000000088.
- Computational PathologyLouis DN, Feldman M, Carter AB, Dighe AS, Pfeifer JD, Bry L, Almeida JS, Saltz J, Braun J, Tomaszewski JE, Gilbertson JR, Sinard JH, Gerber GK, Galli SJ, Golden JA, Becich MJ. Computational Pathology. Archives Of Pathology & Laboratory Medicine 2015, 140: 41-50. PMID: 26098131, PMCID: PMC4996078, DOI: 10.5858/arpa.2015-0093-sa.
- Pathologists' Place in the Electronic Health Record LandscapeHenricks WH, Wilkerson ML, Castellani WJ, Whitsitt MS, Sinard JH. Pathologists' Place in the Electronic Health Record Landscape. Archives Of Pathology & Laboratory Medicine 2015, 139: 307-10. PMID: 25724026, DOI: 10.5858/arpa.2013-0709-so.
- Pathologists as Stewards of Laboratory InformationHenricks WH, Wilkerson ML, Castellani WJ, Whitsitt MS, Sinard JH. Pathologists as Stewards of Laboratory Information. Archives Of Pathology & Laboratory Medicine 2015, 139: 332-7. PMID: 25724030, DOI: 10.5858/arpa.2013-0714-so.
- Management of Laboratory Data and Information Exchange in the Electronic Health RecordWilkerson ML, Henricks WH, Castellani WJ, Whitsitt MS, Sinard JH. Management of Laboratory Data and Information Exchange in the Electronic Health Record. Archives Of Pathology & Laboratory Medicine 2015, 139: 319-27. PMID: 25724028, DOI: 10.5858/arpa.2013-0712-so.
- Accreditation and Regulatory Implications of Electronic Health Records for Laboratory ReportingCastellani WJ, Sinard JH, Wilkerson ML, Whitsitt MS, Henricks WH. Accreditation and Regulatory Implications of Electronic Health Records for Laboratory Reporting. Archives Of Pathology & Laboratory Medicine 2015, 139: 328-31. PMID: 25724029, DOI: 10.5858/arpa.2013-0713-so.
- Stand-alone Laboratory Information Systems Versus Laboratory Modules Incorporated in the Electronic Health RecordSinard JH, Castellani WJ, Wilkerson ML, Henricks WH. Stand-alone Laboratory Information Systems Versus Laboratory Modules Incorporated in the Electronic Health Record. Archives Of Pathology & Laboratory Medicine 2015, 139: 311-8. PMID: 25724027, DOI: 10.5858/arpa.2013-0711-so.
- Review of “digital pathology” by Yves Sucaet and Wim Waelput Y Sucaet W Waelput Review of “digital pathology” by Yves Sucaet and Wim Waelput 2015 Springer New York 83 10:978-3-319-08779-5Sinard J. Review of “digital pathology” by Yves Sucaet and Wim Waelput Y Sucaet W Waelput Review of “digital pathology” by Yves Sucaet and Wim Waelput 2015 Springer New York 83 10:978-3-319-08779-5. Journal Of Pathology Informatics 2015, 6: 12. PMCID: PMC4355838, DOI: 10.1016/s2153-3539(22)00467-9.
- Pathology Training in Informatics: Evolving to Meet a Growing NeedSinard JH, Powell SZ, Karcher DS. Pathology Training in Informatics: Evolving to Meet a Growing Need. Archives Of Pathology & Laboratory Medicine 2014, 138: 505-11. PMID: 24678681, DOI: 10.5858/arpa.2013-0328-ra.
- In Response: It's All About What is TypicalSinard JH. In Response: It's All About What is Typical. Archives Of Pathology & Laboratory Medicine 2014, 138: 869-70. PMID: 24491222, DOI: 10.5858/arpa.2013-0427-edi.
- In Vitro and In Vivo Comparison of Two Suprachoroidal ShuntsComparison of Two Suprachoroidal ShuntsOatts JT, Zhang Z, Tseng H, Shields MB, Sinard JH, Loewen NA. In Vitro and In Vivo Comparison of Two Suprachoroidal ShuntsComparison of Two Suprachoroidal Shunts. Investigative Ophthalmology & Visual Science 2013, 54: 5416-5423. PMID: 23847318, PMCID: PMC4141703, DOI: 10.1167/iovs.13-11853.
- Individual and geographic disparities in human papillomavirus types 16/18 in high‐grade cervical lesionsNiccolai LM, Russ C, Julian PJ, Hariri S, Sinard J, Meek JI, McBride V, Markowitz LE, Unger ER, Hadler JL, Sosa LE. Individual and geographic disparities in human papillomavirus types 16/18 in high‐grade cervical lesions. Cancer 2013, 119: 3052-3058. PMID: 23661284, DOI: 10.1002/cncr.28038.
- Tracking in Anatomic PathologyPantanowitz L, Mackinnon AC, Sinard JH. Tracking in Anatomic Pathology. Archives Of Pathology & Laboratory Medicine 2013, 137: 1798-810. PMID: 23634908, DOI: 10.5858/arpa.2013-0125-sa.
- Validating Whole Slide Imaging for Diagnostic Purposes in Pathology: Guideline from the College of American Pathologists Pathology and Laboratory Quality CenterPantanowitz L, Sinard JH, Henricks WH, Fatheree LA, Carter AB, Contis L, Beckwith BA, Evans AJ, Lal A, Parwani AV. Validating Whole Slide Imaging for Diagnostic Purposes in Pathology: Guideline from the College of American Pathologists Pathology and Laboratory Quality Center. Archives Of Pathology & Laboratory Medicine 2013, 137: 1710-22. PMID: 23634907, PMCID: PMC7240346, DOI: 10.5858/arpa.2013-0093-cp.
- Management of lens dislocation and iris cyst after iris sutured intraocular lens implantation in children with Marfan syndrome.Salchow DJ, Sinard J. Management of lens dislocation and iris cyst after iris sutured intraocular lens implantation in children with Marfan syndrome. Journal Of Pediatric Ophthalmology And Strabismus 2013, 50 Online: e8-10. PMID: 23429576, DOI: 10.3928/01913913-20130219-02.
- Accounting for the Professional Work of Pathologists Performing AutopsiesSinard JH. Accounting for the Professional Work of Pathologists Performing Autopsies. Archives Of Pathology & Laboratory Medicine 2013, 137: 228-32. PMID: 23368865, DOI: 10.5858/arpa.2012-0012-cp.
- Necrobiotic xanthogranuloma and chronic lymphocytic leukemia of the conjunctiva masquerading as scleritis and uveitisMohsenin A, Sinard J, Huang JJ. Necrobiotic xanthogranuloma and chronic lymphocytic leukemia of the conjunctiva masquerading as scleritis and uveitis. Clinical Ophthalmology 2012, Volume 6: 2045-2047. PMID: 23271884, PMCID: PMC3526909, DOI: 10.2147/opth.s35743.
- Recommendations for Validating Whole Slide Imaging in Pathology: College of American Pathologists Pathology and Laboratory Quality CenterPantanowitz L, Sinard J, Fatheree L, Henricks W, Carter A, Contis L, Beckwith B, Evans A, Otis C, MacDonald J, Parwani A. Recommendations for Validating Whole Slide Imaging in Pathology: College of American Pathologists Pathology and Laboratory Quality Center. American Journal Of Clinical Pathology 2012, 138: a194-a194. DOI: 10.1093/ajcp/138.suppl1.178.
- Giant myofibroma of the orbit in an adult male.Servat JJ, Williamson JE, Piepmeier J, Sinard J, Bernardino CR. Giant myofibroma of the orbit in an adult male. Orbit (Amsterdam, Netherlands) 2012, 31: 21-3. PMID: 22007896, DOI: 10.3109/01676830.2011.605501.
- Custom software development for use in a clinical laboratorySinard JH, Gershkovich P. Custom software development for use in a clinical laboratory. Journal Of Pathology Informatics 2012, 3: 44. PMID: 23372985, PMCID: PMC3551490, DOI: 10.4103/2153-3539.104906.
- Pathology informatics fellowship retreats: The use of interactive scenarios and case studies as pathology informatics teaching toolsLee RE, McClintock DS, Balis UJ, Baron JM, Becich MJ, Beckwith BA, Brodsky VB, Carter AB, Dighe AS, Haghighi M, Hipp JD, Henricks WH, Kim JY, Klepseis VE, Kuo FC, Lane WJ, Levy BP, Onozato ML, Park SL, Sinard JH, Tuthill MJ, Gilbertson JR. Pathology informatics fellowship retreats: The use of interactive scenarios and case studies as pathology informatics teaching tools. Journal Of Pathology Informatics 2012, 3: 41. PMID: 23248762, PMCID: PMC3519095, DOI: 10.4103/2153-3539.103995.
- Development and evolution of The Knowledge Hub for Pathology and related electronic resources.Hardwick DF, Sinard J, Silva F. Development and evolution of The Knowledge Hub for Pathology and related electronic resources. Human Pathology 2011, 42: 795-801. PMID: 21316077, DOI: 10.1016/j.humpath.2010.10.019.
- Factor VII–Verteporfin for Targeted Photodynamic Therapy in a Rat Model of Choroidal NeovascularizationLu F, Hu Z, Sinard J, Garen A, Adelman RA. Factor VII–Verteporfin for Targeted Photodynamic Therapy in a Rat Model of Choroidal Neovascularization. Investigative Ophthalmology & Visual Science 2009, 50: 3890-3896. PMID: 19357351, DOI: 10.1167/iovs.08-2833.
- Book Review: Virtual MicroscopySinard J. Book Review: Virtual Microscopy. Pediatric And Developmental Pathology 2008, 11: 69-69. DOI: 10.2350/07-08-0320.1.
- Fatal adenoviral hepatitis after rituximab therapy.Iyer A, Mathur R, Deepak BV, Sinard J. Fatal adenoviral hepatitis after rituximab therapy. Archives Of Pathology & Laboratory Medicine 2006, 130: 1557-60. PMID: 17090202, DOI: 10.5858/2006-130-1557-FAHART.
- Practical Pathology Informatics: demystifying informatics for the practicing anatomic pathologistSinard, J.H. (2006) Practical Pathology Informatics: demystifying informatics for the practicing anatomic pathologist. Springer-Verlag, London. 380pp.
- Overcoming the limitations of integrated clinical digital imaging solutions.Sinard JH, Mattie ME. Overcoming the limitations of integrated clinical digital imaging solutions. Archives Of Pathology & Laboratory Medicine 2005, 129: 1118-26. PMID: 16119983, DOI: 10.5858/2005-129-1118-otloic.
- Comparison of Histopathologic Features, Clinical Symptoms, and Erythrocyte Sedimentation Rates in Biopsy-Positive Temporal ArteritisDiaz VA, DeBroff BM, Sinard J. Comparison of Histopathologic Features, Clinical Symptoms, and Erythrocyte Sedimentation Rates in Biopsy-Positive Temporal Arteritis. Ophthalmology 2005, 112: 1293-1298. PMID: 15921755, DOI: 10.1016/j.ophtha.2005.02.016.
- Cholesterol crystal morphology in acalculous gallbladder disease.Landi K, Sinard J, Crawford JM, Topazian M. Cholesterol crystal morphology in acalculous gallbladder disease. Journal Of Clinical Gastroenterology 2003, 36: 364-6. PMID: 12642747, DOI: 10.1097/00004836-200304000-00017.
- Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma)Hui P, Glusac EJ, Sinard JH, Perkins AS. Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma). Journal Of Cutaneous Pathology 2002, 29: 385-389. PMID: 12139632, DOI: 10.1034/j.1600-0560.2002.290701.x.
- Factors Affecting Autopsy Rates, Autopsy Request Rates, and Autopsy Findings at a Large Academic Medical CenterSinard J. Factors Affecting Autopsy Rates, Autopsy Request Rates, and Autopsy Findings at a Large Academic Medical Center. Experimental And Molecular Pathology 2001, 70: 333-343. PMID: 11418012, DOI: 10.1006/exmp.2001.2371.
- Y2k revisited: a human component?Sinard JH. Y2k revisited: a human component? JAMA 2001, 285: 1706-7. PMID: 11277824, DOI: 10.1001/jama.285.13.1706.
- Informatics and anatomic pathology: Meeting challenges and charting the futureSinard J, Morrow J. Informatics and anatomic pathology: Meeting challenges and charting the future. Human Pathology 2001, 32: 143-148. PMID: 11230700, DOI: 10.1053/hupa.2001.23057.
- Quality improvement on an academic autopsy service.Sinard J, Blood D. Quality improvement on an academic autopsy service. Archives Of Pathology & Laboratory Medicine 2001, 125: 237-45. PMID: 11175642, DOI: 10.5858/2001-125-0237-qioaaa.
- Implementation of a practical digital imaging system for routine gross photography in an autopsy environment.Belanger A, Lopes A, Sinard J. Implementation of a practical digital imaging system for routine gross photography in an autopsy environment. Archives Of Pathology & Laboratory Medicine 2000, 124: 160-5. PMID: 10629152, DOI: 10.5858/2000-124-0160-ioapdi.
- Immunohistochemical distinction of ocular sebaceous carcinoma from basal cell and squamous cell carcinoma.Sinard JH. Immunohistochemical distinction of ocular sebaceous carcinoma from basal cell and squamous cell carcinoma. Archives Of Ophthalmology (Chicago, Ill. : 1960) 1999, 117: 776-83. PMID: 10369589, DOI: 10.1001/archopht.117.6.776.
- Malignant transformation of an optic disk melanocytoma.Meyer D, Ge J, Blinder KJ, Sinard J, Xu S. Malignant transformation of an optic disk melanocytoma. American Journal Of Ophthalmology 1999, 127: 710-4. PMID: 10372881, DOI: 10.1016/s0002-9394(99)00065-3.
- Sebaceous carcinoma presenting as a unilateral papillary conjunctivitis.Gloor P, Ansari I, Sinard J. Sebaceous carcinoma presenting as a unilateral papillary conjunctivitis. American Journal Of Ophthalmology 1999, 127: 458-9. PMID: 10218701, DOI: 10.1016/s0002-9394(98)00383-3.
- Exclusion of the stomatin, α‐adducin and β‐adducin loci in a large kindred with dehydrated hereditary stomatocytosisInnes D, Sinard J, Gilligan D, Snyder L, Gallagher P, Morrow J. Exclusion of the stomatin, α‐adducin and β‐adducin loci in a large kindred with dehydrated hereditary stomatocytosis. American Journal Of Hematology 1999, 60: 72-74. PMID: 9883810, DOI: 10.1002/(sici)1096-8652(199901)60:1<72::aid-ajh13>3.0.co;2-8.
- Pigmented villonodular synovitis of the temporomandibular joint: diagnostic imaging and endovascular therapeutic embolization of a rare head and neck tumor.Bemporad JA, Chaloupka JC, Putman CM, Roth TC, Tarro J, Mitra S, Sinard JH, Sasaki CT. Pigmented villonodular synovitis of the temporomandibular joint: diagnostic imaging and endovascular therapeutic embolization of a rare head and neck tumor. AJNR. American Journal Of Neuroradiology 1999, 20: 159-62. PMID: 9974074.
- Albumin gene expression in adenocarcinomas with hepatoid differentiationFoschini MP, Baccarini P, Dal Monte P, Sinard J, Eusebi V, Rosai J. Albumin gene expression in adenocarcinomas with hepatoid differentiation. Virchows Archiv 1998, 433: 537-541. PMID: 9870687, DOI: 10.1007/s004280050286.
- Orbital Melanoma Presenting as Orbital CellulitisFezza J, Chaudhry I, Kwon Y, Grannum E, Sinard J, Wolfley D. Orbital Melanoma Presenting as Orbital Cellulitis. Ophthalmic Plastic And Reconstructive Surgery 1998, 14: 286-289. PMID: 9700739, DOI: 10.1097/00002341-199807000-00012.
- Utilization of an 86bp exon generates a novel adducin isoform (β4) lacking the MARCKS homology domain1The first two authors contributed equally to this work.1Sinard J, Stewart G, Stabach P, Argent A, Gilligan D, Morrow J. Utilization of an 86bp exon generates a novel adducin isoform (β4) lacking the MARCKS homology domain1The first two authors contributed equally to this work.1. Biochimica Et Biophysica Acta 1998, 1396: 57-66. PMID: 9524222, DOI: 10.1016/s0167-4781(97)00167-x.
- Of Membrane Stability and Mosaics: The Spectrin CytoskeletonMorrow J, Rimm D, Kennedy S, Cianci C, Sinard J, Weed S. Of Membrane Stability and Mosaics: The Spectrin Cytoskeleton. 1997, 485-540. DOI: 10.1002/cphy.cp140111.
- Metastatic Liposarcoma to the OrbitFezza J, Sinard J. Metastatic Liposarcoma to the Orbit. American Journal Of Ophthalmology 1997, 123: 271-272. PMID: 9186144, DOI: 10.1016/s0002-9394(14)71055-4.
- Outlines in PathologySinard, J.H. Outlines in Pathology. W.B. Saunders Company, Philadephia. 229 pages (1996).
- DNA Ploidy as a Significant Predictor of Recurrence‐Free Survival in Male Patients with Breast CancerMani S, Haffty B, Sinard J, Fischer D, Papac R, Flynn S. DNA Ploidy as a Significant Predictor of Recurrence‐Free Survival in Male Patients with Breast Cancer. The Breast Journal 1995, 1: 356-361. DOI: 10.1111/j.1524-4741.1995.tb00262.x.
- Neuronal loss from the subthalamic nuclei in a patient with progressive choreaSinard J, Hedreen J. Neuronal loss from the subthalamic nuclei in a patient with progressive chorea. Movement Disorders 1995, 10: 305-311. PMID: 7651448, DOI: 10.1002/mds.870100313.
- Reduced alpha-catenin and E-cadherin expression in breast cancer.Rimm DL, Sinard JH, Morrow JS. Reduced alpha-catenin and E-cadherin expression in breast cancer. Laboratory Investigation 1995, 72: 506-12. PMID: 7745946.
- Hepatoid adenocarcinoma in the urinary bladder. Unusual localization of a newly recognized tumor typeSinard J, Macleay L, Melamed J. Hepatoid adenocarcinoma in the urinary bladder. Unusual localization of a newly recognized tumor type. Cancer 1994, 73: 1919-1925. PMID: 7511041, DOI: 10.1002/1097-0142(19940401)73:7<1919::aid-cncr2820730724>3.0.co;2-l.
- Cardiogenic Shock Due to Progression of Cutaneous T-Cell LymphomaCOOPER D, SINARD J, EDELSON R, FLYNN S. Cardiogenic Shock Due to Progression of Cutaneous T-Cell Lymphoma. Southern Medical Journal 1994, 87: 89-94. PMID: 8284728, DOI: 10.1097/00007611-199401000-00021.
- Identification of functional regions on the tail of Acanthamoeba myosin-II using recombinant fusion proteins. II. Assembly properties of tails with NH2- and COOH-terminal deletions.Sinard JH, Rimm DL, Pollard TD. Identification of functional regions on the tail of Acanthamoeba myosin-II using recombinant fusion proteins. II. Assembly properties of tails with NH2- and COOH-terminal deletions. Journal Of Cell Biology 1990, 111: 2417-2426. PMID: 2177477, PMCID: PMC2116375, DOI: 10.1083/jcb.111.6.2417.
- A Stopped‐flow/rapid‐freezing machine with millisecond time resolution to prepare intermediates in biochemical reactions for electron microscopyPollard T, Maupin P, Sinard J, Huxley H. A Stopped‐flow/rapid‐freezing machine with millisecond time resolution to prepare intermediates in biochemical reactions for electron microscopy. Microscopy Research And Technique 1990, 16: 160-166. PMID: 2213238, DOI: 10.1002/jemt.1060160206.
- Acanthamoeba myosin-II minifilaments assemble on a millisecond time scale with rate constants greater than those expected for a diffusion limited reaction.Sinard JH, Pollard TD. Acanthamoeba myosin-II minifilaments assemble on a millisecond time scale with rate constants greater than those expected for a diffusion limited reaction. Journal Of Biological Chemistry 1990, 265: 3654-3660. PMID: 2303471, DOI: 10.1016/s0021-9258(19)39643-7.
- The effect of heavy chain phosphorylation and solution conditions on the assembly of Acanthamoeba myosin-II.Sinard JH, Pollard TD. The effect of heavy chain phosphorylation and solution conditions on the assembly of Acanthamoeba myosin-II. Journal Of Cell Biology 1989, 109: 1529-1535. PMID: 2793932, PMCID: PMC2115825, DOI: 10.1083/jcb.109.4.1529.
- The mechanism of assembly of Acanthamoeba myosin-II minifilaments: minifilaments assemble by three successive dimerization steps.Sinard JH, Stafford WF, Pollard TD. The mechanism of assembly of Acanthamoeba myosin-II minifilaments: minifilaments assemble by three successive dimerization steps. Journal Of Cell Biology 1989, 109: 1537-1547. PMID: 2793933, PMCID: PMC2115822, DOI: 10.1083/jcb.109.4.1537.
- Location of the head-tail junction of myosin.Rimm DL, Sinard JH, Pollard TD. Location of the head-tail junction of myosin. Journal Of Cell Biology 1989, 108: 1783-1789. PMID: 2715178, PMCID: PMC2115540, DOI: 10.1083/jcb.108.5.1783.
- Microinjection into Acanthamoeba castellanii of monoclonal antibodies to myosin‐II slows but does not stop cell locomotionSinard J, Pollard T. Microinjection into Acanthamoeba castellanii of monoclonal antibodies to myosin‐II slows but does not stop cell locomotion. Cytoskeleton 1989, 12: 42-52. PMID: 2523248, DOI: 10.1002/cm.970120106.
- Characterization of alpha‐actinin from AcanthamoebaPollard T, Tseng P, Rimm D, Bichell D, Williams R, Sinard J, Sato M. Characterization of alpha‐actinin from Acanthamoeba. Cytoskeleton 1986, 6: 649-661. PMID: 2948678, DOI: 10.1002/cm.970060613.
- The mesothelial keratins: a new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia.Wu YJ, Parker LM, Binder NE, Beckett MA, Sinard JH, Griffiths CT, Rheinwald JG. The mesothelial keratins: a new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia. Cell 1982, 31: 693-703. PMID: 6186388, DOI: 10.1016/0092-8674(82)90324-5.