Jennifer M. Kwan, MD/PhD

• Adam Schussheim
• Albert Sinusas
• Alexander B. Pine
• Anna Shlionsky Bader
• Attila Feher
• Christine Won
• Dana Peters
• Daniel Greif
• David A. Hafler
• David van Dijk
• Diane Krause
• E Kevin Hall
• Edward J Miller
• Erica Spatz
• Erin Faherty
• Erin Longbrake
• F. Perry Wilson
• Francine Foss
• George Goshua
• Giulia Biancon
• Hamid Mojibian
• Hanming Zhang
• Harriet Kluger
• Hongyu Zhao
• Hyung Chun
• Ian Ferguson
• Jennifer VanOudenhove
• Jeremy Asnes
• Jeremy Steele
• John Hwa
• John Stendahl
• Judith Meadows
• Kanika Jain
• Kathleen Martin
• Lajos Pusztai
• Lauren A. Baldassarre
• Laurine Bow
• Lohith Gowda
• Mary Tomayko
• Maryam Lustberg
• Mehran M Sadeghi
• Nihar Desai
• Robert Elder
• Rohan Khera
• Rong Fan
• Sarah C. Hull
• Sean Gu
• Shalin Kothari
• Stephanie Halene
• Tarun Tyagi
• Wade Schulz

Arrhythmias, Cardiac; Medical Oncology; Cardiomyopathies

• Microfluidic Immuno‐Serolomic Assay Reveals Systems Level Association with COVID‐19 Pathology and Vaccine Protection (Small Methods 10/2023)Kim D, Biancon G, Bai Z, VanOudenhove J, Liu Y, Kothari S, Gowda L, Kwan J, Buitrago‐Pocasangre N, Lele N, Asashima H, Racke M, Wilson J, Givens T, Tomayko M, Schulz W, Longbrake E, Hafler D, Halene S, Fan R. Microfluidic Immuno‐Serolomic Assay Reveals Systems Level Association with COVID‐19 Pathology and Vaccine Protection (Small Methods 10/2023). Small Methods 2023, 7 DOI: 10.1002/smtd.202370057.
• Microfluidic Immuno‐Serolomic Assay Reveals Systems Level Association with COVID‐19 Pathology and Vaccine ProtectionKim D, Biancon G, Bai Z, VanOudenhove J, Liu Y, Kothari S, Gowda L, Kwan J, Buitrago‐Pocasangre N, Lele N, Asashima H, Racke M, Wilson J, Givens T, Tomayko M, Schulz W, Longbrake E, Hafler D, Halene S, Fan R. Microfluidic Immuno‐Serolomic Assay Reveals Systems Level Association with COVID‐19 Pathology and Vaccine Protection. Small Methods 2023, 7: e2300594. PMID: 37312418, PMCID: PMC10592458, DOI: 10.1002/smtd.202300594.
• Quantitative cardiovascular magnetic resonance findings and clinical risk factors predict cardiovascular outcomes in breast cancer patientsKwan J, Arbune A, Henry M, Hu R, Wei W, Nguyen V, Lee S, Lopez-Mattei J, Guha A, Huber S, Bader A, Meadows J, Sinusas A, Mojibian H, Peters D, Lustberg M, Hull S, Baldassarre L. Quantitative cardiovascular magnetic resonance findings and clinical risk factors predict cardiovascular outcomes in breast cancer patients. PLOS ONE 2023, 18: e0286364. PMID: 37252927, PMCID: PMC10228774, DOI: 10.1371/journal.pone.0286364.
• Abstract 13769: AT1R Autoantibody Levels Are Elevated in Patients Who Required Immunosuppression Escalation in Immune Checkpoint Inhibitor Mediated MyocarditisAkhlaghi N, Shen M, Bow L, Miller M, Hwa J, Halene S, Baldassarre L, Kwan J. Abstract 13769: AT1R Autoantibody Levels Are Elevated in Patients Who Required Immunosuppression Escalation in Immune Checkpoint Inhibitor Mediated Myocarditis. Circulation 2022, 146: a13769-a13769. DOI: 10.1161/circ.146.suppl_1.13769.
• Short-Term Outcomes After Myopericarditis Related to COVID-19 VaccinationPareek M, Steele J, Asnes J, Baldassarre L, Casale L, Desai N, Elder R, Faherty E, Ferguson I, Fishman R, Ghazizadeh Z, Glick L, Hall E, Khera R, Kokkinidis D, Kwan J, O'Marr J, Schussheim A, Tuohy E, Wang Y, Spatz E, Jacoby D, Miller E. Short-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination. JACC Cardiovascular Imaging 2022, 15: 2002-2005. PMID: 36357140, PMCID: PMC9094612, DOI: 10.1016/j.jcmg.2022.03.026.
• Radiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 1: Technical Considerations and Perfusion and Neuronal Imaging.Stendahl JC, Kwan JM, Pucar D, Sadeghi MM. Radiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 1: Technical Considerations and Perfusion and Neuronal Imaging. Journal Of Nuclear Medicine 2022, 63: 649-658. PMID: 35487563, DOI: 10.2967/jnumed.121.263506.
• Multimodality Advanced Cardiovascular and Molecular Imaging for Early Detection and Monitoring of Cancer Therapy-Associated Cardiotoxicity and the Role of Artificial Intelligence and Big DataKwan JM, Oikonomou EK, Henry ML, Sinusas AJ. Multimodality Advanced Cardiovascular and Molecular Imaging for Early Detection and Monitoring of Cancer Therapy-Associated Cardiotoxicity and the Role of Artificial Intelligence and Big Data. Frontiers In Cardiovascular Medicine 2022, 9: 829553. PMID: 35369354, PMCID: PMC8964995, DOI: 10.3389/fcvm.2022.829553.
• MYOCARDIAL IMPACT OF CLONAL HEMATOPOIESIS OF INDETERMINATE POTENTIAL (CHIP) SECRETOMES IN CARDIO-ONCOLOGY PATIENTSKwan J, Vanoudenhove J, Halder S, Biancon G, Jain K, Chakraborty R, Lustberg M, Pusztai L, Campbell S, Zhao H, Halene S, Hwa J. MYOCARDIAL IMPACT OF CLONAL HEMATOPOIESIS OF INDETERMINATE POTENTIAL (CHIP) SECRETOMES IN CARDIO-ONCOLOGY PATIENTS. Journal Of The American College Of Cardiology 2022, 79: 1912. DOI: 10.1016/s0735-1097(22)02903-5.
• ADVERSE CARDIOVASCULAR EVENTS ASSOCIATED WITH KINASE INHIBITORS IN THE TREATMENT OF CANCER REVEAL SPECIFIC RISK BASED ON THE KINASE INHIBITOR - A SINGLE-CENTER RETROSPECTIVE COHORT STUDYKwan J, Shen M, Mankbadi M, Wang P, Zaman S, Lee S, Jiang M, Tao W, Wei W, Akhlaghi N. ADVERSE CARDIOVASCULAR EVENTS ASSOCIATED WITH KINASE INHIBITORS IN THE TREATMENT OF CANCER REVEAL SPECIFIC RISK BASED ON THE KINASE INHIBITOR - A SINGLE-CENTER RETROSPECTIVE COHORT STUDY. Journal Of The American College Of Cardiology 2022, 79: 1924. DOI: 10.1016/s0735-1097(22)02915-1.
• ADVERSE CARDIOVASCULAR EVENTS ASSOCIATED WITH IMMUNE CHECKPOINT INHIBITORS - A SINGLE CENTER RETROSPECTIVE COHORT STUDYKwan J, Akhlaghi N, Jiang M, Shen M, Im Y, Mankbadi M, Wang P, Zaman S, Lee S, Tao W, Wei W, Ma S. ADVERSE CARDIOVASCULAR EVENTS ASSOCIATED WITH IMMUNE CHECKPOINT INHIBITORS - A SINGLE CENTER RETROSPECTIVE COHORT STUDY. Journal Of The American College Of Cardiology 2022, 79: 1909. DOI: 10.1016/s0735-1097(22)02900-x.
• Gender disparities among medical students choosing to pursue careers in medical research: a secondary cross-sectional cohort analysisSnyder A, Xiang D, Smith A, Esswein S, Toubat O, Di Capua J, Kwan JM, Daye D. Gender disparities among medical students choosing to pursue careers in medical research: a secondary cross-sectional cohort analysis. BMC Medical Education 2021, 21: 591. PMID: 34823508, PMCID: PMC8620216, DOI: 10.1186/s12909-021-03004-z.
• Adverse cardiovascular events in patients treated with mogamulizumabKwan J, Henry M, Cook K, Higgins A, Cuomo J, Foss F, Baldassarre L. Adverse cardiovascular events in patients treated with mogamulizumab. American Heart Journal Plus Cardiology Research And Practice 2021, 9: 100049. PMCID: PMC10978139, DOI: 10.1016/j.ahjo.2021.100049.
• The Role and Impact of Social Media in Cardio-oncology During the COVID-19 PandemicKwan JM, Henry ML, Christophers B, Tamirisa K, Thamman R, Sadler D, Aggarwal NR, Cheng R, Parwani P, Dent S, Ismail-Khan R, Fradley MG, Brown SA. The Role and Impact of Social Media in Cardio-oncology During the COVID-19 Pandemic. Current Oncology Reports 2021, 23: 99. PMID: 34259950, PMCID: PMC8278372, DOI: 10.1007/s11912-021-01081-3.
• A new classification of cardio-oncology syndromesde Boer RA, Aboumsallem JP, Bracun V, Leedy D, Cheng R, Patel S, Rayan D, Zaharova S, Rymer J, Kwan JM, Levenson J, Ronco C, Thavendiranathan P, Brown SA. A new classification of cardio-oncology syndromes. Cardio-Oncology 2021, 7: 24. PMID: 34154667, PMCID: PMC8218489, DOI: 10.1186/s40959-021-00110-1.
• Mogamulizumab-Associated Acute Myocarditis in a Patient With T-Cell LymphomaKwan JM, Odanovic N, Arbune A, Higgins A, Henry M, Greif D, Foss F, Baldassarre LA. Mogamulizumab-Associated Acute Myocarditis in a Patient With T-Cell Lymphoma. JACC Case Reports 2021, 3: 1018-1023. PMID: 34317676, PMCID: PMC8311348, DOI: 10.1016/j.jaccas.2021.04.001.
• CARDIOVASCULAR AND MORTALITY OUTCOMES IN ONCOLOGY PATIENTS HOSPITALIZED WITH COVID-19Kwan J, Lee S, Tao W, Wei W, Simonov M, Halene S, Hwa J, Baldassarre L. CARDIOVASCULAR AND MORTALITY OUTCOMES IN ONCOLOGY PATIENTS HOSPITALIZED WITH COVID-19. Journal Of The American College Of Cardiology 2021, 77: 3294. PMCID: PMC8091382, DOI: 10.1016/s0735-1097(21)04648-9.
• CARDIOVASCULAR AND MORTALITY OUTCOMES OF HOSPITALIZED COVID-19 PATIENTS STRATIFIED BY RACE AND ETHNICITYKwan J, Lee S, Tao W, Wei W, Simonov M, Halene S, Hwa J, Spatz E. CARDIOVASCULAR AND MORTALITY OUTCOMES OF HOSPITALIZED COVID-19 PATIENTS STRATIFIED BY RACE AND ETHNICITY. Journal Of The American College Of Cardiology 2021, 77: 3050. PMCID: PMC8091439, DOI: 10.1016/s0735-1097(21)04405-3.
• 57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicityCuomo J, Ragheb E, Feher A, Kwan J, Huber S, Mojibian H, Peters D, Sinusas A, Baldassarre L. 57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicity. Journal Of Clinical And Translational Science 2021, 5: 141-142. PMCID: PMC8827987, DOI: 10.1017/cts.2021.761.
• A neutrophil activation signature predicts critical illness and mortality in COVID-19Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun HJ. A neutrophil activation signature predicts critical illness and mortality in COVID-19. Blood Advances 2021, 5: 1164-1177. PMID: 33635335, PMCID: PMC7908851, DOI: 10.1182/bloodadvances.2020003568.
• Left ventricular myocardial strain and tissue characterization by cardiac magnetic resonance imaging in immune checkpoint inhibitor associated cardiotoxicityHiggins AY, Arbune A, Soufer A, Ragheb E, Kwan JM, Lamy J, Henry M, Cuomo JR, Charifa A, Gallegos C, Hull S, Coviello JS, Bader AS, Peters DC, Huber S, Mojibian HR, Sinusas AJ, Kluger H, Baldassarre LA. Left ventricular myocardial strain and tissue characterization by cardiac magnetic resonance imaging in immune checkpoint inhibitor associated cardiotoxicity. PLOS ONE 2021, 16: e0246764. PMID: 33606757, PMCID: PMC7895343, DOI: 10.1371/journal.pone.0246764.
• Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammationGu SX, Tyagi T, Jain K, Gu VW, Lee SH, Hwa JM, Kwan JM, Krause DS, Lee AI, Halene S, Martin KA, Chun HJ, Hwa J. Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation. Nature Reviews Cardiology 2020, 18: 194-209. PMID: 33214651, PMCID: PMC7675396, DOI: 10.1038/s41569-020-00469-1.
• Factors associated with underrepresented minority physician scientist trainee career choicesSiebert AL, Chou S, Toubat O, Adami AJ, Kim H, Daye D, Kwan JM. Factors associated with underrepresented minority physician scientist trainee career choices. BMC Medical Education 2020, 20: 422. PMID: 33176758, PMCID: PMC7656762, DOI: 10.1186/s12909-020-02328-6.
• Circulating markers of angiogenesis and endotheliopathy in COVID‐19Pine AB, Meizlish ML, Goshua G, Chang C, Zhang H, Bishai J, Bahel P, Patel A, Gbyli R, Kwan JM, Won CH, Price C, Dela Cruz CS, Halene S, van Dijk D, Hwa J, Lee AI, Chun HJ. Circulating markers of angiogenesis and endotheliopathy in COVID‐19. Pulmonary Circulation 2020, 10: 1-4. PMID: 33282193, PMCID: PMC7691906, DOI: 10.1177/2045894020966547.
• A nationwide assessment of perceptions of research-intense academic careers among predoctoral MD and MD-PhD traineesKwan JM, Toubat O, Harrison AM, Riddle M, Wu B, Kim H, Basta DW, Adami AJ, Daye D. A nationwide assessment of perceptions of research-intense academic careers among predoctoral MD and MD-PhD trainees. Journal Of Clinical And Translational Science 2020, 4: 307-316. PMID: 33244411, PMCID: PMC7681110, DOI: 10.1017/cts.2020.18.
• A NATIONWIDE ASSESSMENT OF FACTORS INFLUENCING RESEARCH AND ACADEMIC CAREERS AMONG MD AND MD-PHD TRAINEES INTERESTED IN CARDIOLOGYKwan J, Toubat O, Kim H, Daye D. A NATIONWIDE ASSESSMENT OF FACTORS INFLUENCING RESEARCH AND ACADEMIC CAREERS AMONG MD AND MD-PHD TRAINEES INTERESTED IN CARDIOLOGY. Journal Of The American College Of Cardiology 2020, 75: 3512. DOI: 10.1016/s0735-1097(20)34139-5.
• Hepatotoxicity and Recurrent NSTEMI While on Pembrolizumab for Metastatic Giant Cell Bone Tumor.Kwan JM, Cheng R, Feldman LE. Hepatotoxicity and Recurrent NSTEMI While on Pembrolizumab for Metastatic Giant Cell Bone Tumor. The American Journal Of The Medical Sciences 2019, 357: 343-347. PMID: 30638772, DOI: 10.1016/j.amjms.2018.11.017.
• CARDIAC MAGNETIC RESONANCE IMAGING FEATURE TRACKING STRAIN AS A SENSITIVE MARKER OF CARDIOTOXICITY IN BREAST CANCER PATIENTS COMPARED WITH LEFT VENTRICULAR EJECTION FRACTIONKwan J, Arbune A, Henry M, Dupee D, Soufer A, Baldassarre L. CARDIAC MAGNETIC RESONANCE IMAGING FEATURE TRACKING STRAIN AS A SENSITIVE MARKER OF CARDIOTOXICITY IN BREAST CANCER PATIENTS COMPARED WITH LEFT VENTRICULAR EJECTION FRACTION. Journal Of The American College Of Cardiology 2019, 73: 1666. DOI: 10.1016/s0735-1097(19)32272-7.
• Donor and Recipient Ethnicity Impacts Renal Graft Adverse Outcomes.Kwan JM, Hajjiri Z, Chen YF, Metwally A, Perkins DL, Finn PW. Donor and Recipient Ethnicity Impacts Renal Graft Adverse Outcomes. Journal Of Racial And Ethnic Health Disparities 2018, 5: 1003-1013. PMID: 29270842, DOI: 10.1007/s40615-017-0447-9.
• Exploring intentions of physician-scientist trainees: factors influencing MD and MD/PhD interest in research careersKwan JM, Daye D, Schmidt ML, Conlon CM, Kim H, Gaonkar B, Payne AS, Riddle M, Madera S, Adami AJ, Winter KQ. Exploring intentions of physician-scientist trainees: factors influencing MD and MD/PhD interest in research careers. BMC Medical Education 2017, 17: 115. PMID: 28697782, PMCID: PMC5505137, DOI: 10.1186/s12909-017-0954-8.
• Effect of the Obesity Epidemic on Kidney Transplantation: Obesity Is Independent of Diabetes as a Risk Factor for Adverse Renal Transplant Outcomes.Kwan JM, Hajjiri Z, Metwally A, Finn PW, Perkins DL. Effect of the Obesity Epidemic on Kidney Transplantation: Obesity Is Independent of Diabetes as a Risk Factor for Adverse Renal Transplant Outcomes. PloS One 2016, 11: e0165712. PMID: 27851743, PMCID: PMC5112887, DOI: 10.1371/journal.pone.0165712.
• T cells and lung injury. Impact of rapamycin.Nakajima T, Lin KW, Li J, McGee HS, Kwan JM, Perkins DL, Finn PW. T cells and lung injury. Impact of rapamycin. American Journal Of Respiratory Cell And Molecular Biology 2014, 51: 294-9. PMID: 24641710, PMCID: PMC4148036, DOI: 10.1165/rcmb.2013-0171OC.
• Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis.Nogueira V, Sundararajan D, Kwan JM, Peng XD, Sarvepalli N, Sonenberg N, Hay N. Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis. The EMBO Journal 2012, 31: 1134-46. PMID: 22307088, PMCID: PMC3297989, DOI: 10.1038/emboj.2011.478.
• The Anticancer Activity of the N-Terminal CARD-Like Domain of Arginine Deiminase (ADI) from Pseudomonas aeruginosaKundu M, Thomas J, Fialho A, Kwan J, Moreira L, Mahfouz M, Das Gupta T, Chakrabarty A. The Anticancer Activity of the N-Terminal CARD-Like Domain of Arginine Deiminase (ADI) from Pseudomonas aeruginosa. Letters In Drug Design & Discovery 2009, 6: 403-412. DOI: 10.2174/157018009789057580.
• Bacterial proteins as potential drugs in the treatment of leukemiaKwan JM, Fialho AM, Kundu M, Thomas J, Hong CS, Gupta T, Chakrabarty AM. Bacterial proteins as potential drugs in the treatment of leukemia. Leukemia Research 2009, 33: 1392-1399. PMID: 19250673, DOI: 10.1016/j.leukres.2009.01.024.
• Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition.Choi SH, Byun HM, Kwan JM, Issa JP, Yang AS. Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition. British Journal Of Haematology 2007, 138: 616-23. PMID: 17686055, DOI: 10.1111/j.1365-2141.2007.06707.x.
• Rapid and quantitative method of allele-specific DNA methylation analysis.Wong HL, Byun HM, Kwan JM, Campan M, Ingles SA, Laird PW, Yang AS. Rapid and quantitative method of allele-specific DNA methylation analysis. BioTechniques 2006, 41: 734-9. PMID: 17191619, DOI: 10.2144/000112305.
• Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.Chuang JC, Yoo CB, Kwan JM, Li TW, Liang G, Yang AS, Jones PA. Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine. Molecular Cancer Therapeutics 2005, 4: 1515-20. PMID: 16227400, DOI: 10.1158/1535-7163.MCT-05-0172.
• Immunity regulatory DNAs share common organizational features in Drosophila.Senger K, Armstrong GW, Rowell WJ, Kwan JM, Markstein M, Levine M. Immunity regulatory DNAs share common organizational features in Drosophila. Molecular Cell 2004, 13: 19-32. PMID: 14731391.