Jaya Prakash Golla, PhD
Associate Research Scientist (Endocrinology)
Research & Publications
Biography
News
Coauthors
Selected Publications
- Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol‐Induced Liver DamageKoelmel JP, Tan WY, Li Y, Bowden JA, Ahmadireskety A, Patt AC, Orlicky DJ, Mathé E, Kroeger NM, Thompson DC, Cochran JA, Golla JP, Kandyliari A, Chen Y, Charkoftaki G, Guingab‐Cagmat J, Tsugawa H, Arora A, Veselkov K, Kato S, Otoki Y, Nakagawa K, Yost RA, Garrett TJ, Vasiliou V. Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol‐Induced Liver Damage. Hepatology Communications 2022, 6: 513-525. PMID: 34811964, PMCID: PMC8870008, DOI: 10.1002/hep4.1825.
- Molecular Mechanisms of Alcohol-Induced Colorectal CarcinogenesisJohnson CH, Golla JP, Dioletis E, Singh S, Ishii M, Charkoftaki G, Thompson DC, Vasiliou V. Molecular Mechanisms of Alcohol-Induced Colorectal Carcinogenesis. Cancers 2021, 13: 4404. PMID: 34503214, PMCID: PMC8431530, DOI: 10.3390/cancers13174404.
- Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 functionThompson B, Chen Y, Davidson EA, Garcia-Milian R, Golla JP, Apostolopoulos N, Orlicky DJ, Schey K, Thompson DC, Vasiliou V. Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function. The Ocular Surface 2021, 22: 190-203. PMID: 34425299, PMCID: PMC8560581, DOI: 10.1016/j.jtos.2021.08.010.
- Identification of Dose-Dependent DNA Damage and Repair Responses From Subchronic Exposure to 1,4-Dioxane in Mice Using a Systems Analysis Approach.Charkoftaki G, Golla JP, Santos-Neto A, Orlicky DJ, Garcia-Milian R, Chen Y, Rattray NJW, Cai Y, Wang Y, Shearn CT, Mironova V, Wang Y, Johnson CH, Thompson DC, Vasiliou V. Identification of Dose-Dependent DNA Damage and Repair Responses From Subchronic Exposure to 1,4-Dioxane in Mice Using a Systems Analysis Approach. Toxicological Sciences 2021, 183: 338-351. PMID: 33693819, PMCID: PMC8921626, DOI: 10.1093/toxsci/kfab030.
- Interplay between APC and ALDH1B1 in a newly developed mouse model of colorectal cancerGolla JP, Kandyliari A, Tan WY, Chen Y, Orlicky DJ, Thompson DC, Shah YM, Vasiliou V. Interplay between APC and ALDH1B1 in a newly developed mouse model of colorectal cancer. Chemico-Biological Interactions 2020, 331: 109274. PMID: 33007288, PMCID: PMC9201852, DOI: 10.1016/j.cbi.2020.109274.
- Science of superstimulationGolla JP, Golla SK, Shelling AN. Science of superstimulation. Fertility And Sterility 2020, 114: 504-505. PMID: 32912611, DOI: 10.1016/j.fertnstert.2020.07.015.
- Antiproliferative activity of protein hydrolysates derived from fish by-products on human colon and breast cancer cells.Kandyliari A, Golla J, Chen Y, Papandroulakis N, Kapsokefalou M, Vasiliou V. Antiproliferative activity of protein hydrolysates derived from fish by-products on human colon and breast cancer cells. Proceedings Of The Nutrition Society 2020, 79: e282. DOI: 10.1017/s002966512000230x.
- Nutrient Composition and Fatty Acid and Protein Profiles of Selected Fish By-ProductsKandyliari A, Mallouchos A, Papandroulakis N, Golla JP, Lam TT, Sakellari A, Karavoltsos S, Vasiliou V, Kapsokefalou M. Nutrient Composition and Fatty Acid and Protein Profiles of Selected Fish By-Products. Foods 2020, 9: 190. PMID: 32075005, PMCID: PMC7074476, DOI: 10.3390/foods9020190.
- Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cellsCharkoftaki G, Thompson DC, Golla JP, Garcia-Milian R, Lam TT, Engel J, Vasiliou V. Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells. Chemico-Biological Interactions 2019, 304: 88-96. PMID: 30851239, PMCID: PMC7988342, DOI: 10.1016/j.cbi.2019.02.030.
- Engineered Animal Models Designed for Investigating Ethanol Metabolism, Toxicity and CancerMarshall S, Chen Y, Singh S, Berrios-Carcamo P, Heit C, Apostolopoulos N, Golla JP, Thompson DC, Vasiliou V. Engineered Animal Models Designed for Investigating Ethanol Metabolism, Toxicity and Cancer. 2018, 1032: 203-221. PMID: 30362100, PMCID: PMC6743736, DOI: 10.1007/978-3-319-98788-0_14.
- Metabolomic Analysis of Mice Exposed to Gamma Radiation Reveals a Systemic Understanding of Total-Body ExposureGolla S, Golla JP, Krausz KW, Manna SK, Simillion C, Beyoğlu D, Idle JR, Gonzalez FJ. Metabolomic Analysis of Mice Exposed to Gamma Radiation Reveals a Systemic Understanding of Total-Body Exposure. Radiation Research 2017, 187: 612-629. PMID: 28467754, PMCID: PMC5539505, DOI: 10.1667/rr14592.1.
- St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory SignalingManna SK, Golla S, Golla JP, Tanaka N, Cai Y, Takahashi S, Krausz KW, Matsubara T, Korboukh I, Gonzalez FJ. St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling. Cancer Prevention Research 2015, 8: 786-795. PMID: 26069204, PMCID: PMC4584416, DOI: 10.1158/1940-6207.capr-14-0113.
- C/EBPβ (CEBPB) protein binding to the C/EBP|CRE DNA 8-mer TTGC|GTCA is inhibited by 5hmC and enhanced by 5mC, 5fC, and 5caC in the CG dinucleotideSayeed SK, Zhao J, Sathyanarayana BK, Golla JP, Vinson C. C/EBPβ (CEBPB) protein binding to the C/EBP|CRE DNA 8-mer TTGC|GTCA is inhibited by 5hmC and enhanced by 5mC, 5fC, and 5caC in the CG dinucleotide. Biochimica Et Biophysica Acta 2015, 1849: 583-589. PMID: 25779641, PMCID: PMC7857639, DOI: 10.1016/j.bbagrm.2015.03.002.
- Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG|GTG) increases binding of the Tcf3|Ascl1 helix-loop-helix heterodimer 10-foldGolla JP, Zhao J, Mann IK, Sayeed SK, Mandal A, Rose RB, Vinson C. Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG|GTG) increases binding of the Tcf3|Ascl1 helix-loop-helix heterodimer 10-fold. Biochemical And Biophysical Research Communications 2014, 449: 248-255. PMID: 24835951, PMCID: PMC6258048, DOI: 10.1016/j.bbrc.2014.05.018.
- Relevance of syndecan-1 in the trophoblastic BeWo cell syncytialization.Prakash GJ, Suman P, Gupta SK. Relevance of syndecan-1 in the trophoblastic BeWo cell syncytialization. American Journal Of Reproductive Immunology (New York, N.Y. : 1989) 2011, 66: 385-93. PMID: 21623993, DOI: 10.1111/j.1600-0897.2011.01017.x.
- Mutational analysis of JAG1 gene in non-syndromic Tetralogy of Fallot childrenKola S, Koneti NR, Golla JP, Akka J, Gundimeda SD, Mundluru HP. Mutational analysis of JAG1 gene in non-syndromic Tetralogy of Fallot children. Clinica Chimica Acta 2011, 412: 2232-2236. PMID: 21893051, DOI: 10.1016/j.cca.2011.08.017.
- Leukaemia inhibitory factor mediated proliferation of HTR-8/SVneo trophoblast cells is dependent on activation of extracellular signal-regulated kinase 1/2.Prakash GJ, Suman P, Morales Prieto DM, Markert UR, Gupta SK. Leukaemia inhibitory factor mediated proliferation of HTR-8/SVneo trophoblast cells is dependent on activation of extracellular signal-regulated kinase 1/2. Reproduction, Fertility, And Development 2011, 23: 714-24. PMID: 21635820, DOI: 10.1071/RD10315.
- Interleukin-11 increases invasiveness of JEG-3 choriocarcinoma cells by modulating STAT3 expression.Suman P, Poehlmann TG, Prakash GJ, Markert UR, Gupta SK. Interleukin-11 increases invasiveness of JEG-3 choriocarcinoma cells by modulating STAT3 expression. Journal Of Reproductive Immunology 2009, 82: 1-11. PMID: 19716605, DOI: 10.1016/j.jri.2009.07.002.