Research & Publications
I am an epileptologist interested in the use of neurostimulation in epilepsy, the use of implanted brain stimulators to gather long-term ambulatory EEG, as well as epilepsy neurogenetics and particularly channelopathies.
Extensive Research Description
- Long-term ambulatory recordings from the responsive neurostimulation system (RNS) and thalamic deep brain stimulation (DBS) devices, which are implanted into the brain to treat epilepsy.
- Clinical trials of brain stimulation to treat epilepsy.
- Use of intracranial EEG from surgical epilepsy patients and from RNS to study cognitive neuroscience of language and memory.
- Seizure forecasting based on intracranial EEG biomarkers.
- Electric and magnetic source localization, including magnetoencephalography (MEG) to understand epilepsy networks.
- PET imaging with novel tracers to visualize the effects of brain stimulation and brain dysfunction in epilepsy.
- Cellular and animal models of KCNT1 potassium channelopathies
- Anti-sense oligonucleotides and new medications to treat epilepsy due to KCNT1 mutations
Biomedical Engineering; Electric Stimulation; Electroencephalography; Epilepsy; Ion Channels; Neurosciences; Seizures; Computational Biology; Channelopathies; Cognitive Neuroscience