Ichiro Ikuta, MD, MMSc

• Adel Mustafa
• Dorothy Sippo
• Lawrence Staib
• Mariam Aboian
• Merceditas Villanueva
• Michele Johnson
• Sacit Bulent Omay
• Sam Payabvash

Artificial Intelligence; Medical Informatics; Minocycline; Natural Language Processing; Radiation Dosage; Radiation Monitoring; Radiology; Spinal Muscular Atrophies of Childhood; Apoptosis; Informatics; Functional Neuroimaging

Bioinformatics; Health Informatics

• Machine Learning Tools for Image-Based Glioma Grading and the Quality of Their Reporting: Challenges and Opportunities.Merkaj S, Bahar RC, Zeevi T, Lin M, Ikuta I, Bousabarah K, Cassinelli Petersen GI, Staib L, Payabvash S, Mongan JT, Cha S, Aboian MS. Machine Learning Tools for Image-Based Glioma Grading and the Quality of Their Reporting: Challenges and Opportunities. Cancers 2022, 14 PMID: 35681603, DOI: 10.3390/cancers14112623.
• The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic ClassificationBaid U, Ghodasara S, Mohan S, Bilello M, Calabrese E, Colak E, Farahani K, Kalpathy-Cramer J, Kitamura FC, Pati S, Prevedello LM, Rudie JD, Sako C, Shinohara RT, Bergquist T, Chai R, Eddy J, Elliott J, Reade W, Schaffter T, Yu T, Zheng J, Moawad AW, Coelho LO, McDonnell O, Miller E, Moron FE, Oswood MC, Shih RY, Siakallis L, Bronstein Y, Mason JR, Miller AF, Choudhary G, Agarwal A, Besada CH, Derakhshan JJ, Diogo MC, Do-Dai DD, Farage L, Go JL, Hadi M, Hill VB, Iv M, Joyner D, Lincoln C, Lotan E, Miyakoshi A, Montano MS, Nath J, Nguyen XV, Nicolas-Jilwan M, Jimenez JO, Ozturk K, Petrovic BD, Shah C, Shah LM, Sharma M, Simsek O, Singh AK, Soman S, Statsevych V, Weinberg BD, Young RJ, Ikuta I, Agarwal AK, Cambron SC, Silbergleit R, Alexandru Dusoi A, Postma AA, Letourneau-Guillon L, Perez-Carrillo GJG, Saha A, Soni N, Zaharchuk G, Zohrabian VM, Chen Y, Cekic MM, Rahman A, Small JE, Sethi V, Davatzikos C, Mongan J, Hess C, Cha S, Villanueva-Meyer J, Freymann JB, Kirby JS, Wiestler B, Crivellaro P, Colen R, Kotrotsou A, Marcus D, Milchenko M, Nazeri A, Fathallah-Shaykh H, Wiest R, Jakab A, Weber MA, Mahajan A, Menze B, The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification, Flanders AE, and Bakas S
• Review of Artificial Intelligence Training Tools and Courses for Radiologists.Richardson ML, Adams SJ, Agarwal A, Auffermann WF, Bhattacharya AK, Consul N, Fotos JS, Kelahan LC, Lin C, Lo HS, Nguyen XV, Salkowski LR, Sin JM, Thomas RC, Wassef S, Ikuta I. Review of Artificial Intelligence Training Tools and Courses for Radiologists. Academic Radiology 2021, 28: 1238-1252. PMID: 33714667, DOI: 10.1016/j.acra.2020.12.026.
• Construction of a Machine Learning Dataset through Collaboration: The RSNA 2019 Brain CT Hemorrhage Challenge.Flanders AE, Prevedello LM, Shih G, Halabi SS, Kalpathy-Cramer J, Ball R, Mongan JT, Stein A, Kitamura FC, Lungren MP, Choudhary G, Cala L, Coelho L, Mogensen M, Morón F, Miller E, Ikuta I, Zohrabian V, McDonnell O, Lincoln C, Shah L, Joyner D, Agarwal A, Lee RK, Nath J. Construction of a Machine Learning Dataset through Collaboration: The RSNA 2019 Brain CT Hemorrhage Challenge. Radiology. Artificial Intelligence 2020, 2: e190211. PMID: 33937827, PMCID: PMC8082297, DOI: 10.1148/ryai.2020190211.
• Erratum: Construction of a Machine Learning Dataset through Collaboration: The RSNA 2019 Brain CT Hemorrhage Challenge.Flanders AE, Prevedello LM, Shih G, Halabi SS, Kalpathy-Cramer J, Ball R, Mongan JT, Stein A, Kitamura FC, Lungren MP, Choudhary G, Cala L, Coelho L, Mogensen M, Morón F, Miller E, Ikuta I, Zohrabian V, McDonnell O, Lincoln C, Shah L, Joyner D, Agarwal A, Lee RK, Nath J. Erratum: Construction of a Machine Learning Dataset through Collaboration: The RSNA 2019 Brain CT Hemorrhage Challenge. Radiology. Artificial Intelligence 2020, 2: e209002. PMID: 33939782, PMCID: PMC8082367, DOI: 10.1148/ryai.2020209002.
• NIMG-38. Identifying Clinically Applicable Machine Learning Algorithms for Glioma Segmentation Using a Systematic Literature Review.1. Tillmanns N, Lum A, Brim WR, Subramanian H, Lin M, Bousabarah K, Malhotra A, Cui J, Brackett A, Payabvash S, Ikuta I, Johnson M, Turowski B, Aboian M, NIMG-38. Identifying Clinically Applicable Machine Learning Algorithms for Glioma Segmentation Using a Systematic Literature Review, Neuro-Oncology, Volume 23, Issue Supplement_6, November 2021, Page vi137.
• NIMG-71. Identifying Clinically Applicable Machine Learning Algorithms for Glioma Segmentation Using a Systematic Literature ReviewTillmanns N, Lum A, Brim WR, Subramanian H, Lin M, Bousabarah K, Malhotra A, Cui J, Brackett A, Payabvash S, Ikuta I, Johnson M, Turowski B, Aboian M, NIMG-38. Identifying Clinically Applicable Machine Learning Algorithms for Glioma Segmentation Using a Systematic Literature Review, Neuro-Oncology, Volume 23, Issue Supplement_6, November 2021, Page vi137, https://doi.org/10.1093/neuonc/noab196.537
• NIMG-46. Systematic Literature Review of Artificial Intelligence Algorithsm Using Pre-Thereapy MR Imaging for Glioma Molecular Subtype Classification.3. Lost J, Verma T, Tillmanns N, Brim WR, Subramanian H, Ikuta I, Bronen R, Zucconi W, Lin M, Bousabarah K, Johnson MH, Cui J, Malhotra A, Sabel M, Aboian M. NIMG-46. Systematic Literature Review of Artificial Intelligence Algorithsm Using Pre-Thereapy MR Imaging for Glioma Molecular Subtype Classification. Neuro-Oncology. Volume 23, Issue Supplement_6, November 2021, Page vi139.
• OTHR-06. PACS Lesion Tracking Tool provides real time automatic information on brain tumor metastasis growth curves and RECIST criteriaJang B, Lin M, Owens R, Bousabarah K, Mahajan A, Abi Fadel S, Ikuta I, Tocino I, Aboian M. OTHR-06. PACS Lesion Tracking Tool provides real time automatic information on brain tumor metastasis growth curves and RECIST criteria. Neuro-Oncology Advances, Volume 3, Issue Supplement_3, August 2021, Page iii15.
• A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT.Seifert KD, Zohrabian VM, Ikuta I. A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT. The Yale Journal Of Biology And Medicine 2021, 94: 599-602. PMID: 34970097, PMCID: PMC8686775.
• Sinonasal Glomangiopericytoma: Review of Imaging Appearance and Clinical Management Update for a Rare Sinonasal Neoplasm.Al-Jobory YM, Pan Z, Manes RP, Omay SB, Ikuta I. Sinonasal Glomangiopericytoma: Review of Imaging Appearance and Clinical Management Update for a Rare Sinonasal Neoplasm. The Yale Journal Of Biology And Medicine 2021, 94: 593-597. PMID: 34970096, PMCID: PMC8686777.
• A Brief Guide to the Neuroradiology FellowshipTu LH, Aboian M, Ikuta I. "Checklists for Advanced MRI Studies." A Brief Guide to the Neuroradiology Fellowship. Independently Published; 2021 June 27. pp. 107-126.
• A Brief Guide to the Neuroradiology FellowshipTu LH, Mahajan A, Ikuta I. "Search Patterns for Uncommon CT Studies." A Brief Guide to the Neuroradiology Fellowship. Independently Published; 2021 June 27. pp. 92-106.
• A Brief Guide to the Neuroradiology FellowshipTu LH, Payabvash S, Ikuta I. "Search Patterns for Uncommon MRI Exams." A Brief Guide to the Neuroradiology Fellowship. Independently Published; 2021 June 27. pp. 68-91.
• Brain Tumor Reporting and Data System: A Pictorial ReviewRao B, Ikuta I, Mahajan A, Karam AA, Zohrabian VM. Brain Tumor Reporting and Data System: A Pictorial Review. Neurographics. 5/1/2021. Volume 11, Issue 3, Pages 175-185.
• MRI in Spine TraumaDuy P.Q., Ikuta I., Johnson M.H., Davis M., Zohrabian V.M. (2020) MRI in Spine Trauma. In: Morrison W., Carrino J., Flanders A. (eds) MRI of the Spine: A Guide for Orthopedic Surgeons. Springer, Cham
• Level of Evidence during the COVID-19 Pandemic: Making the Case for Case Series and Case Reports.Ikuta I. Level of Evidence during the COVID-19 Pandemic: Making the Case for Case Series and Case Reports. AJNR. American Journal Of Neuroradiology 2020 PMID: 32616587, DOI: 10.3174/ajnr.A6676.
• Search Pattern: A Systematic Approach to Diagnostic ImagingTu LH, Ikuta I. “Neuroimaging: Radiographic Studies.” Search Pattern: A Systematic Approach to Diagnostic Imaging. Independently Published; 2020 Jun 30. pp. 70-80.
• Search Pattern: A Systematic Approach to Diagnostic ImagingTu LH, Ikuta I. “Neuroimaging: CT Studies.” Search Pattern: A Systematic Approach to Diagnostic Imaging. Independently Published; 2020 Jun 30. pp. 81-112.
• Search Pattern: A Systematic Approach to Diagnostic ImagingTu LH, Ikuta I. “Neuroimaging: MRI Studies.” Search Pattern: A Systematic Approach to Diagnostic Imaging. Independently Published; 2020 Jun 30. pp. 113-146.
• PerspectivesIkuta I. Perspectives. AJNR Am J Neuroradiol. April 2019.
• Regarding "Measured Head CT/CTA Skin Dose and Intensive Care Unit Patient Cumulative Exposure".Ikuta I, Mustafa A, Johnson MH. Regarding "Measured Head CT/CTA Skin Dose and Intensive Care Unit Patient Cumulative Exposure". AJNR. American Journal Of Neuroradiology 2017, 38: E55. PMID: 28546242, DOI: 10.3174/ajnr.A5234.
• Estimating patient dose from x-ray tube output metrics: automated measurement of patient size from CT images enables large-scale size-specific dose estimates.Ikuta I, Warden GI, Andriole KP, Khorasani R, Sodickson A. Estimating patient dose from x-ray tube output metrics: automated measurement of patient size from CT images enables large-scale size-specific dose estimates. Radiology 2014, 270: 472-80. PMID: 24086075, PMCID: PMC4228751, DOI: 10.1148/radiol.13122727.
• Exposing exposure: automated anatomy-specific CT radiation exposure extraction for quality assurance and radiation monitoring.Sodickson A, Warden GI, Farkas CE, Ikuta I, Prevedello LM, Andriole KP, Khorasani R. Exposing exposure: automated anatomy-specific CT radiation exposure extraction for quality assurance and radiation monitoring. Radiology 2012, 264: 397-405. PMID: 22668563, PMCID: PMC3422099, DOI: 10.1148/radiol.12111822.
• Exposing exposure: enhancing patient safety through automated data mining of nuclear medicine reports for quality assurance and organ dose monitoring.Ikuta I, Sodickson A, Wasser EJ, Warden GI, Gerbaudo VH, Khorasani R. Exposing exposure: enhancing patient safety through automated data mining of nuclear medicine reports for quality assurance and organ dose monitoring. Radiology 2012, 264: 406-13. PMID: 22627599, PMCID: PMC3401350, DOI: 10.1148/radiol.12111823.
• Radiation Exposure from Medical Imaging: Imaging Informatics for Computed Tomography & Nuclear MedicineIkuta I. Radiation Exposure from Medical Imaging: Imaging Informatics for Computed Tomography & Nuclear Medicine. Harvard Medical School, Countway Library, Post-Doctoral Fellowship Thesis. 2012 May.
• Automated extraction of BI-RADS final assessment categories from radiology reports with natural language processing.Sippo DA, Warden GI, Andriole KP, Lacson R, Ikuta I, Birdwell RL, Khorasani R. Automated extraction of BI-RADS final assessment categories from radiology reports with natural language processing. Journal Of Digital Imaging 2013, 26: 989-94. PMID: 23868515, PMCID: PMC3782591, DOI: 10.1007/s10278-013-9616-5.
• Paradoxical Reaction in a Patient with Co-Occurring Tuberculous Meningitis and Pott's Disease.Robledo-Gil T, Harada K, Ikuta I, Villanueva M. Paradoxical Reaction in a Patient with Co-Occurring Tuberculous Meningitis and Pott's Disease. The American Journal Of Case Reports 2018, 19: 699-704. PMID: 29907737, PMCID: PMC6034555, DOI: 10.12659/AJCR.909194.
• Extraocular muscle belly enlargement with myotendinous sparing in thyroid-associated orbitopathyGautier A, Ikuta I, Zucconi W. Extraocular muscle belly enlargement with myotendinous sparing in thyroid-associated orbitopathy. Digital Journal of Ophthalmology. 2017 December. Volume 23, Number 4.
• Letter by Bonaque et al regarding article, "Cardiac biomarkers are associated with an increased risk of stroke and death in patients with atrial fibrillation: a randomized evaluation of long-term anticoagulation therapy (RE-LY) substudy".Bonaque JC, Merchán G, Ikuta I. Letter by Bonaque et al regarding article, "Cardiac biomarkers are associated with an increased risk of stroke and death in patients with atrial fibrillation: a randomized evaluation of long-term anticoagulation therapy (RE-LY) substudy". Circulation 2013, 127: e277. PMID: 23319819, DOI: 10.1161/CIRCULATIONAHA.112.114421.
• Neuroanatomic alterations and social and communication deficits in monozygotic twins discordant for autism disorder.Mitchell SR, Reiss AL, Tatusko DH, Ikuta I, Kazmerski DB, Botti JA, Burnette CP, Kates WR. Neuroanatomic alterations and social and communication deficits in monozygotic twins discordant for autism disorder. The American Journal Of Psychiatry 2009, 166: 917-25. PMID: 19605538, DOI: 10.1176/appi.ajp.2009.08101538.
• Gyrification patterns in monozygotic twin pairs varying in discordance for autism.Kates WR, Ikuta I, Burnette CP. Gyrification patterns in monozygotic twin pairs varying in discordance for autism. Autism Research : Official Journal Of The International Society For Autism Research 2009, 2: 267-78. PMID: 19890876, DOI: 10.1002/aur.98.
• A bibliometric evaluation of the top 100 cited natalizumab articles.García-Fernández FJ, García-Fernández AE, Nava E, Del Pozo JSG, Ikuta I, Jordan J, Galindo MF. A bibliometric evaluation of the top 100 cited natalizumab articles. Journal Of Neuroimmunology 2020, 349: 577379. PMID: 33007648, DOI: 10.1016/j.jneuroim.2020.577379.
• A Bibliometric Evaluation of the Top 100 Cited Dimethyl Fumarate Articles.García-Fernández FJ, García-Fernández AE, Ikuta I, Nava E, Solis García Del Pozo J, Jordan J, Galindo MF. A Bibliometric Evaluation of the Top 100 Cited Dimethyl Fumarate Articles. Molecules (Basel, Switzerland) 2021, 26 PMID: 33669498, PMCID: PMC7922659, DOI: 10.3390/molecules26041085.
• Systematic review and meta-analysis on the safety of dalbavancin.Monteagudo-Martínez N, Solís-García Del Pozo J, Ikuta I, Galindo M, Jordán J. Systematic review and meta-analysis on the safety of dalbavancin. Expert Opinion On Drug Safety 2021, 20: 1095-1107. PMID: 34042549, DOI: 10.1080/14740338.2021.1935864.
• Acute Bacterial Skin and Skin-Structure Infections, efficacy of Dalbavancin: a systematic review and meta-analysis.Monteagudo-Martínez N, Solís-García Del Pozo J, Nava E, Ikuta I, Galindo M, Jordán J. Acute Bacterial Skin and Skin-Structure Infections, efficacy of Dalbavancin: a systematic review and meta-analysis. Expert Review Of Anti-infective Therapy 2020, 1-13. PMID: 32981375, DOI: 10.1080/14787210.2021.1828865.
• Long-term prognostic value of a peak exercise echocardiogram in diabetic patients admitted for chest painMerchan Ortega G, Bravo Bustos D, Lazaro Garcia R, Sanchez Espino AD, Macancela Quinones JJ, Ikuta I, Ruiz Lopez MF, Valencia Serrano FM, Bonaque Gonzalez JC, Gomez Recio M. Long-term prognostic value of a peak exercise echocardiogram in diabetic patients admitted for chest pain. European Heart Journal-Cardiovascular Imaging. 1 December 2014, Volume 15, Issue Suppl_2.
• Is the systolic aortic regurgitation phenomenon related with heart failure prognosis?Alejandro Dionisio Sanchez Espino, Bonaque Gonzalez JC, Merchan Ortega G, Ikuta I, Macancela Quinones JJ, Bolivar Herrera N, Gomez Recio M. Is the systolic aortic regurgitation phenomenon related with heart failure prognosis? European Journal of Heart Failure. May 16, 2014. Volume 16, Issue S2, Page 73.
• Systolic Aortic Regurgitation: An Underestimated Phenomenon Related to Heart Failure Prognosis?Sanchez Espino AD, Bonaque González JC, Merchan Ortega G, Ikuta I, Macancela Quinonez JJ, Bolivar Herrera N. Systolic Aortic Regurgitation: An Underestimated Phenomenon Related to Heart Failure Prognosis? Journal of the American College of Cardiology. 2014. Volume 63, Issue 12 Supplement
• Long-Term Prognostic Value of a Peak Exercise Echocardiogram in Patients Admitted for Low-Intermediate Risk Chest PainBonaque Gonzalez JC, Merchan Ortega G, Sanchez Espino A, Ikuta I. Long-Term Prognostic Value of a Peak Exercise Echocardiogram in Patients Admitted for Low-Intermediate Risk Chest Pain. Journal of the American College of Cardiology. 2014. Volume 63, Issue 12 Supplement
• Mitochondrial biology in Alzheimer's disease pathogenesis.Galindo MF, Ikuta I, Zhu X, Casadesus G, Jordán J. Mitochondrial biology in Alzheimer's disease pathogenesis. Journal Of Neurochemistry 2010, 114: 933-45. PMID: 20492350, DOI: 10.1111/j.1471-4159.2010.06814.x.
• Superoxide dismutases: a physiopharmacological update.Valdivia A, Pérez-Alvarez S, Aroca-Aguilar JD, Ikuta I, Jordán J. Superoxide dismutases: a physiopharmacological update. Journal Of Physiology And Biochemistry 2009, 65: 195-208. PMID: 19886398, DOI: 10.1007/BF03179070.
• Stroke pathophysiology: management challenges and new treatment advances.Jordán J, Ikuta I, García-García J, Calleja S, Segura T. Stroke pathophysiology: management challenges and new treatment advances. Journal Of Physiology And Biochemistry 2007, 63: 261-77. PMID: 18309782, DOI: 10.1007/BF03165789.
• Minocycline and cytoprotection: shedding new light on a shadowy controversy.Jordan J, Fernandez-Gomez FJ, Ramos M, Ikuta I, Aguirre N, Galindo MF. Minocycline and cytoprotection: shedding new light on a shadowy controversy. Current Drug Delivery 2007, 4: 225-31. PMID: 17627496, DOI: 10.2174/156720107781023938.