Huabing Li, PhD
Assistant Professor Adjunct
Research & Publications
Biography
Coauthors
Selected Publications
- Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster.Li HB, Müller M, Bahechar IA, Kyrchanova O, Ohno K, Georgiev P, Pirrotta V. Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster. Molecular And Cellular Biology 2011, 31:616-25.
- Insulators target active genes to transcription factories and polycomb-repressed genes to polycomb bodies.Li HB, Ohno K, Gui H, Pirrotta V. Insulators target active genes to transcription factories and polycomb-repressed genes to polycomb bodies. PLoS Genetics 2013, 9:e1003436.
- The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.Hu B, Jin C, Li HB, Tong J, Ouyang X, Cetinbas NM, Zhu S, Strowig T, Lam FC, Zhao C, Henao-Mejia J, Yilmaz O, Fitzgerald KA, Eisenbarth SC, Elinav E, Flavell RA. The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury. Science (New York, N.Y.) 2016, 354:765-768.
- m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.Li HB, Tong J, Zhu S, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z, Flavell RA. m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways. Nature 2017, 548:338-342.
- m6A mRNA methylation sustains Treg suppressive functions.Tong J, Cao G, Zhang T, Sefik E, Amezcua Vesely MC, Broughton JP, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA, Li HB. m6A mRNA methylation sustains Treg suppressive functions. Cell Research 2018, 28:253-256.
- mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence.Hwang SS, Lim J, Yu Z, Kong P, Sefik E, Xu H, Harman CCD, Kim LK, Lee GR, Li HB, Flavell RA. mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence. Science (New York, N.Y.) 2020, 367:1255-1260.