Research & Publications
Dr. Allore's research is focused on issues related to the design and analysis of studies of multi-component interventions and the design and analysis of observational studies of multifactorial geriatric health conditions. Other areas of her applied research include developing strategies for handling missing data that frequently occurs in studies of older persons, applying extended Cox models for state transitions in geriatrics, such as frailty and disability that consist of multiple discrete states in which both onset and recovery are possible, and determining the mechanisms of action of an effective multi-component intervention. She has collaborated on several projects in immunology and is introducing new analytic methods to account for correlations among elements of the innate immune system. She developed a subdiscipline of biostatistics within the American Statistical Association that focuses on training and methodological development in Aging Research called "Gerontologic Biostatistics." This discipline trains biostatisticians for conducting collaborative clinical research with geriatricians and gerontologists in elderly populations and provide the basis for the development new statistical methodology. She served on the NIH Aging Systems and Geriatrics study section, VA Human Rights Committee, and CDC Special Emphasis study section. She has served as a reviewer and editorial board member for a variety of medical journals.
Specialized Terms: State transition models; Experimental design; Longitudinal methods; Missing data Methods; Marginal structural models; Latent class models; Trajectory models; Dynamic stochastic models; Joint models
Extensive Research Description
Dr. Allore's current research includes analytic methods for Alzheimer's and related dementias, polypharmacy, functional and mobility disability in the older adults, differences in immune system function of between young and older persons, and multiple comorbid conditions.
She is also developing a subdiscipline of biostatistics within the American Statistical Association that focuses on training and methodological development in geriatrics called “gerontologic biostatistics.” This discipline trains biostatisticians for conducting collaborative clinical research with geriatricians and gerontologists in elderly populations and provide the basis for the development new statistical methodology.
Aging; Geriatrics; Statistics as Topic; Frail Elderly; Mathematical Concepts; Biostatistics
Public Health Interests
Aging; Epidemiology Methods