Hanming Zhang, PhD
Postdoctoral Associate
Research & Publications
Biography
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Selected Publications
- A neutrophil activation signature predicts critical illness and mortality in COVID-19.Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun HJ. A neutrophil activation signature predicts critical illness and mortality in COVID-19. Blood Advances 2021, 5: 1164-1177. PMID: 33635335, PMCID: PMC7908851, DOI: 10.1182/bloodadvances.2020003568.
- Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study.Goshua G, Pine AB, Meizlish ML, Chang CH, Zhang H, Bahel P, Baluha A, Bar N, Bona RD, Burns AJ, Dela Cruz CS, Dumont A, Halene S, Hwa J, Koff J, Menninger H, Neparidze N, Price C, Siner JM, Tormey C, Rinder HM, Chun HJ, Lee AI. Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study. The Lancet. Haematology 2020, 7: e575-e582. PMID: 32619411, PMCID: PMC7326446, DOI: 10.1016/S2352-3026(20)30216-7.
- Circulating markers of angiogenesis and endotheliopathy in COVID-19.Pine AB, Meizlish ML, Goshua G, Chang CH, Zhang H, Bishai J, Bahel P, Patel A, Gbyli R, Kwan JM, Won CH, Price C, Dela Cruz CS, Halene S, van Dijk D, Hwa J, Lee AI, Chun HJ. Circulating markers of angiogenesis and endotheliopathy in COVID-19. Pulmonary Circulation 2020, 10: 2045894020966547. PMID: 33282193, PMCID: PMC7691906, DOI: 10.1177/2045894020966547.
- PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy.Zhang H, Pan B, Wu P, Parajuli N, Rekhter MD, Goldberg AL, Wang X. PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy. Science Advances 2019, 5: eaaw5870. PMID: 31131329, PMCID: PMC6531002, DOI: 10.1126/sciadv.aaw5870.
- TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux.Pan B, Zhang H, Cui T, Wang X. TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux. Journal Of Molecular And Cellular Cardiology 2017, 113: 51-62. PMID: 28993153, PMCID: PMC5656243, DOI: 10.1016/j.yjmcc.2017.10.003.
- COP9 signalosome controls the degradation of cytosolic misfolded proteins and protects against cardiac proteotoxicity.Su H, Li J, Zhang H, Ma W, Wei N, Liu J, Wang X. COP9 signalosome controls the degradation of cytosolic misfolded proteins and protects against cardiac proteotoxicity. Circulation Research 2015, 117: 956-66. PMID: 26383969, PMCID: PMC4636927, DOI: 10.1161/CIRCRESAHA.115.306783.
- Priming the proteasome by protein kinase G: a novel cardioprotective mechanism of sildenafil.Zhang H, Wang X. Priming the proteasome by protein kinase G: a novel cardioprotective mechanism of sildenafil. Future Cardiology 2015, 11: 177-89. PMID: 25760877, PMCID: PMC4370174, DOI: 10.2217/fca.15.3.
- Expression and Functional Analysis of Storage Protein 2 in the Silkworm, Bombyx mori.Yu W, Wang M, Zhang H, Quan Y, Zhang Y. Expression and Functional Analysis of Storage Protein 2 in the Silkworm, Bombyx mori. International Journal Of Genomics 2013, 2013: 145450. PMID: 23671839, PMCID: PMC3647547, DOI: 10.1155/2013/145450.
- Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.. Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection. Sci Immunol 2021, 6.