Gita Pathak, PhD
Postdoctoral Associate
Research & Publications
Biography
News
Coauthors
Selected Publications
- Multi-environment gene interactions linked to the interplay between polysubstance dependence and suicidality.Polimanti R, Levey DF, Pathak GA, Wendt FR, Nunez YZ, Ursano RJ, Kessler RC, Kranzler HR, Stein MB, Gelernter J. Multi-environment gene interactions linked to the interplay between polysubstance dependence and suicidality. Translational Psychiatry 2021, 11:34.
- Epigenomic Profiles of African-American Transthyretin Val122Ile Carriers Reveals Putatively Dysregulated Amyloid Mechanisms.Pathak GA, Wendt FR, De Lillo A, Nunez YZ, Goswami A, De Angelis F, Fuciarelli M, Kranzler HR, Gelernter J, Polimanti R. Epigenomic Profiles of African-American Transthyretin Val122Ile Carriers Reveals Putatively Dysregulated Amyloid Mechanisms. Circulation. Genomic And Precision Medicine 2021, 14:e003011.
- Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program.Stein MB, Levey DF, Cheng Z, Wendt FR, Harrington K, Pathak GA, Cho K, Quaden R, Radhakrishnan K, Girgenti MJ, Ho YA, Posner D, Aslan M, Duman RS, Zhao H, Polimanti R, Concato J, Gelernter J. Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program. Nature Genetics 2021, 53:174-184.
- Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer.Pathak GA, Zhou Z, Silzer TK, Barber RC, Phillips NR. Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer. Alzheimer's & Dementia : The Journal Of The Alzheimer's Association 2020, 16:162-177.
- Heterogeneity and Polygenicity in Psychiatric Disorders: A Genome-Wide Perspective.Wendt FR, Pathak GA, Tylee DS, Goswami A, Polimanti R. Heterogeneity and Polygenicity in Psychiatric Disorders: A Genome-Wide Perspective. Chronic Stress (Thousand Oaks, Calif.) 2020, 4:2470547020924844.
- Polygenic risk for autism spectrum disorder associates with anger recognition in a neurodevelopment-focused phenome-wide scan of unaffected youths from a population-based cohort.Wendt FR, Carvalho CM, Pathak GA, Gelernter J, Polimanti R. Polygenic risk for autism spectrum disorder associates with anger recognition in a neurodevelopment-focused phenome-wide scan of unaffected youths from a population-based cohort. PLoS Genetics 2020, 16:e1009036.
- Genetically-regulated transcriptomics & copy number variation of proctitis points to altered mitochondrial and DNA repair mechanisms in individuals of European ancestry.Pathak GA, Polimanti R, Silzer TK, Wendt FR, Chakraborty R, Phillips NR. Genetically-regulated transcriptomics & copy number variation of proctitis points to altered mitochondrial and DNA repair mechanisms in individuals of European ancestry. BMC Cancer 2020, 20:954.
- ACE2 Netlas: In-silico functional characterization and drug-gene interactions of ACE2 gene network to understand its potential involvement in COVID-19 susceptibility.Pathak GA, Wendt FR, Goswami A, De Angelis F, Polimanti R. ACE2 Netlas: In-silico functional characterization and drug-gene interactions of ACE2 gene network to understand its potential involvement in COVID-19 susceptibility. MedRxiv : The Preprint Server For Health Sciences 2020.
- Epigenetic profiling of Italian patients identified methylation sites associated with hereditary transthyretin amyloidosis.De Lillo A, Pathak GA, De Angelis F, Di Girolamo M, Luigetti M, Sabatelli M, Perfetto F, Frusconi S, Manfellotto D, Fuciarelli M, Polimanti R. Epigenetic profiling of Italian patients identified methylation sites associated with hereditary transthyretin amyloidosis. Clinical Epigenetics 2020, 12:176.
- Host genetic liability for severe COVID-19 overlaps with alcohol drinking behavior and diabetic outcomes in over 1 million participants.Wendt FR, De Lillo A, Pathak GA, De Angelis F, Polimanti R. Host genetic liability for severe COVID-19 overlaps with alcohol drinking behavior and diabetic outcomes in over 1 million participants. MedRxiv : The Preprint Server For Health Sciences 2020.
- Attachment Style Moderates Polygenic Risk for Posttraumatic Stress in United States Military Veterans: Results From the National Health and Resilience in Veterans Study.Tamman AJF, Wendt FR, Pathak GA, Krystal JH, Montalvo-Ortiz JL, Southwick SM, Sippel LM, Gelernter J, Polimanti R, Pietrzak RH. Attachment Style Moderates Polygenic Risk for Posttraumatic Stress in United States Military Veterans: Results From the National Health and Resilience in Veterans Study. Biological Psychiatry 2021, 89:878-887.
- Multivariate genome-wide analysis of education, socioeconomic status and brain phenome.Wendt FR, Pathak GA, Lencz T, Krystal JH, Gelernter J, Polimanti R. Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Nature Human Behaviour 2021, 5:482-496.
- Integrative analyses identify susceptibility genes underlying COVID-19 hospitalization.Pathak GA, Singh K, Miller-Fleming TW, Wendt F, Ehsan N, Hou K, Johnson R, Lu Z, Gopalan S, Dimbou LY, Mohammadi P, Pasaniuc B, Polimanti R, Davis LK, Mancuso N. Integrative analyses identify susceptibility genes underlying COVID-19 hospitalization. MedRxiv : The Preprint Server For Health Sciences 2020.
- Deciphering the Biological Mechanisms Underlying the Genome-Wide Associations between Computerized Device Use and Psychiatric Disorders.Wendt FR, Muniz Carvalho C, Pathak GA, Gelernter J, Polimanti R. Deciphering the Biological Mechanisms Underlying the Genome-Wide Associations between Computerized Device Use and Psychiatric Disorders. Journal Of Clinical Medicine 2019, 8.
- Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans.Silzer T, Barber R, Sun J, Pathak G, Johnson L, O'Bryant S, Phillips N. Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans. PloS One 2019, 14:e0213527.
- Genome-Wide Methylation of Mild Cognitive Impairment in Mexican Americans Highlights Genes Involved in Synaptic Transport, Alzheimer's Disease-Precursor Phenotypes, and Metabolic Morbidities.Pathak GA, Silzer TK, Sun J, Zhou Z, Daniel AA, Johnson L, O'Bryant S, Phillips NR, Barber RC. Genome-Wide Methylation of Mild Cognitive Impairment in Mexican Americans Highlights Genes Involved in Synaptic Transport, Alzheimer's Disease-Precursor Phenotypes, and Metabolic Morbidities. Journal Of Alzheimer's Disease : JAD 2019, 72:733-749.
- Global genetic variation of select opiate metabolism genes in self-reported healthy individuals.Wendt FR, Pathak G, Sajantila A, Chakraborty R, Budowle B. Global genetic variation of select opiate metabolism genes in self-reported healthy individuals. The Pharmacogenomics Journal 2018, 18:281-294.