Frederic Pincet, PhD
Associate Research Scientist in Cell Biology
Research & Publications
Biography
Research Summary
I am a CNRS scientist from the Laboratoire de Physique Statistique of the
Ecole Normale Supérieure in Paris, France, where I am interested in various
interactions of membranes and/or single molecules. During my sabbatical stay in
the laboratory of Prof. J. Rothman I am studying the thermo-mechanical impact of
SNAREpins on membranes by combining theoretical predictions and
micromanipulation experiments.
Coauthors
Selected Publications
- Analyzing single-bond experiments: influence of the shape of the energy landscape and universal law between the width, depth, and force spectrum of the bond.Husson J, Pincet F. Analyzing single-bond experiments: influence of the shape of the energy landscape and universal law between the width, depth, and force spectrum of the bond. Physical Review. E, Statistical, Nonlinear, And Soft Matter Physics 2008, 77: 026108. PMID: 18352091, DOI: 10.1103/PhysRevE.77.026108.
- Mapping mouse gamete interaction forces reveal several oocyte membrane regions with different mechanical and adhesive properties.Jégou A, Pincet F, Perez E, Wolf JP, Ziyyat A, Gourier C. Mapping mouse gamete interaction forces reveal several oocyte membrane regions with different mechanical and adhesive properties. Langmuir : The ACS Journal Of Surfaces And Colloids 2008, 24: 1451-8. PMID: 18027975, DOI: 10.1021/la702258x.
- Functional adhesiveness of the CX3CL1 chemokine requires its aggregation. Role of the transmembrane domain.Hermand P, Pincet F, Carvalho S, Ansanay H, Trinquet E, Daoudi M, Combadière C, Deterre P. Functional adhesiveness of the CX3CL1 chemokine requires its aggregation. Role of the transmembrane domain. The Journal Of Biological Chemistry 2008, 283: 30225-34. PMID: 18725411, PMCID: PMC2662081, DOI: 10.1074/jbc.M802638200.
- Confinement free energy of surfaces bearing end-grafted polymers in the mushroom regime and local measurement of the polymer density.Li F, Pincet F. Confinement free energy of surfaces bearing end-grafted polymers in the mushroom regime and local measurement of the polymer density. Langmuir : The ACS Journal Of Surfaces And Colloids 2007, 23: 12541-8. PMID: 17988162, DOI: 10.1021/la7021374.
- Energetics and dynamics of SNAREpin folding across lipid bilayers.Li F, Pincet F, Perez E, Eng WS, Melia TJ, Rothman JE, Tareste D. Energetics and dynamics of SNAREpin folding across lipid bilayers. Nature Structural & Molecular Biology 2007, 14: 890-6. PMID: 17906638, DOI: 10.1038/nsmb1310.
- Transition from long- to short-lived transient pores in giant vesicles in an aqueous medium.Rodriguez N, Cribier S, Pincet F. Transition from long- to short-lived transient pores in giant vesicles in an aqueous medium. Physical Review. E, Statistical, Nonlinear, And Soft Matter Physics 2006, 74: 061902. PMID: 17280091, DOI: 10.1103/PhysRevE.74.061902.
- The solution to the streptavidin-biotin paradox: the influence of history on the strength of single molecular bonds.Pincet F, Husson J. The solution to the streptavidin-biotin paradox: the influence of history on the strength of single molecular bonds. Biophysical Journal 2005, 89: 4374-81. PMID: 16169976, PMCID: PMC1367001, DOI: 10.1529/biophysj.105.067769.
- Johnson-Kendall-Roberts theory applied to living cells.Chu YS, Dufour S, Thiery JP, Perez E, Pincet F. Johnson-Kendall-Roberts theory applied to living cells. Physical Review Letters 2005, 94: 028102. PMID: 15698233, DOI: 10.1103/PhysRevLett.94.028102.