Fan Li, PhD
Assistant Professor of Biostatistics
Research & Publications
Biography
News
Locations
Coauthors
Research Interests
Longitudinal Studies; Research Design; Selection Bias; Causality; Survival Analysis; Randomized Controlled Trial; Biostatistics; Propensity Score; Observational Study; Pragmatic Clinical Trial; Implementation Science
Public Health Interests
Aging; Clinical Trials; Bayesian Statistics; Implementation Science; Survival Analysis
Selected Publications
- Sample size calculators for planning stepped-wedge cluster randomized trials: a review and comparison.Ouyang Y, Li F, Preisser JS, Taljaard M. Sample size calculators for planning stepped-wedge cluster randomized trials: a review and comparison. International Journal Of Epidemiology 2022 PMID: 35679584, DOI: 10.1093/ije/dyac123.
- Clustered restricted mean survival time regression.Chen X, Harhay MO, Li F. Clustered restricted mean survival time regression. Biometrical Journal. Biometrische Zeitschrift 2022 PMID: 35593026, DOI: 10.1002/bimj.202200002.
- Power analysis for cluster randomized trials with continuous coprimary endpoints.Yang S, Moerbeek M, Taljaard M, Li F. Power analysis for cluster randomized trials with continuous coprimary endpoints. Biometrics 2022 PMID: 35531926, DOI: 10.1111/biom.13692.
- Ethical considerations within pragmatic randomized controlled trials in dementia: Results from a literature survey.Nicholls SG, Carroll K, Nix HP, Li F, Hey SP, Mitchell SL, Weijer C, Taljaard M. Ethical considerations within pragmatic randomized controlled trials in dementia: Results from a literature survey. Alzheimer's & Dementia (New York, N. Y.) 2022, 8: e12287. PMID: 35509502, PMCID: PMC9060321, DOI: 10.1002/trc2.12287.
- Stepped Wedge Cluster Randomized Trials: A Methodological Overview.Li F, Wang R. Stepped Wedge Cluster Randomized Trials: A Methodological Overview. World Neurosurgery 2022, 161: 323-330. PMID: 35505551, PMCID: PMC9074087, DOI: 10.1016/j.wneu.2021.10.136.
- Design and analysis of partially randomized preference trials with propensity score stratification.Wang Y, Li F, Blaha O, Meng C, Esserman D. Design and analysis of partially randomized preference trials with propensity score stratification. Statistical Methods In Medical Research 2022, 9622802221095673. PMID: 35469503, DOI: 10.1177/09622802221095673.
- Pragmatic clinical trial design in emergency medicine: study considerations and design types.Gettel CJ, Yiadom MYAB, Bernstein SL, Grudzen CR, Nath B, Li F, Hwang U, Hess EP, Melnick ER. Pragmatic clinical trial design in emergency medicine: study considerations and design types. Academic Emergency Medicine : Official Journal Of The Society For Academic Emergency Medicine 2022 PMID: 35475533, DOI: 10.1111/acem.14513.
- Power considerations for generalized estimating equations analyses of four-level cluster randomized trials.Wang X, Turner EL, Preisser JS, Li F. Power considerations for generalized estimating equations analyses of four-level cluster randomized trials. Biometrical Journal. Biometrische Zeitschrift 2022, 64: 663-680. PMID: 34897793, DOI: 10.1002/bimj.202100081.
- Blood pressure response to commonly administered antihypertensives for severe inpatient hypertension.Ghazi L, Li F, Chen X, Simonov M, Yamamoto Y, Biswas A, Hanna J, Shah T, Peixoto AJ, Wilson FP. Blood pressure response to commonly administered antihypertensives for severe inpatient hypertension. PloS One 2022, 17: e0265497. PMID: 35385506, PMCID: PMC8985959, DOI: 10.1371/journal.pone.0265497.
- Finite-sample adjustments in variance estimators for clustered competing risks regression.Chen X, Li F. Finite-sample adjustments in variance estimators for clustered competing risks regression. Statistics In Medicine 2022, 41: 2645-2664. PMID: 35288959, DOI: 10.1002/sim.9375.
- A comparison of analytical strategies for cluster randomized trials with survival outcomes in the presence of competing risks.Li F, Lu W, Wang Y, Pan Z, Greene EJ, Meng G, Meng C, Blaha O, Zhao Y, Peduzzi P, Esserman D. A comparison of analytical strategies for cluster randomized trials with survival outcomes in the presence of competing risks. Statistical Methods In Medical Research 2022, 9622802221085080. PMID: 35290139, DOI: 10.1177/09622802221085080.
- Addressing Extreme Propensity Scores in Estimating Counterfactual Survival Functions via the Overlap Weights.Cheng C, Li F, Thomas LE, Li F. Addressing Extreme Propensity Scores in Estimating Counterfactual Survival Functions via the Overlap Weights. American Journal Of Epidemiology 2022, 191: 1140-1151. PMID: 35238335, DOI: 10.1093/aje/kwac043.
- Cigarette Smoking and Risk of Different Pathologic Types of Stroke: A Systematic Review and Dose-Response Meta-Analysis.Luo J, Tang X, Li F, Wen H, Wang L, Ge S, Tang C, Xu N, Lu L. Cigarette Smoking and Risk of Different Pathologic Types of Stroke: A Systematic Review and Dose-Response Meta-Analysis. Frontiers In Neurology 2021, 12: 772373. PMID: 35145466, PMCID: PMC8821532, DOI: 10.3389/fneur.2021.772373.
- Constrained randomization and statistical inference for multi-arm parallel cluster randomized controlled trials.Zhou Y, Turner EL, Simmons RA, Li F. Constrained randomization and statistical inference for multi-arm parallel cluster randomized controlled trials. Statistics In Medicine 2022, 41: 1862-1883. PMID: 35146788, PMCID: PMC9007899, DOI: 10.1002/sim.9333.
- Clarifying selection bias in cluster randomized trials.Li F, Tian Z, Bobb J, Papadogeorgou G, Li F. Clarifying selection bias in cluster randomized trials. Clinical Trials (London, England) 2022, 19: 33-41. PMID: 34894795, DOI: 10.1177/17407745211056875.
- Two weights make a wrong: Cluster randomized trials with variable cluster sizes and heterogeneous treatment effects.Wang X, Turner EL, Li F, Wang R, Moyer J, Cook AJ, Murray DM, Heagerty PJ. Two weights make a wrong: Cluster randomized trials with variable cluster sizes and heterogeneous treatment effects. Contemporary Clinical Trials 2022, 114: 106702. PMID: 35123029, PMCID: PMC8936048, DOI: 10.1016/j.cct.2022.106702.
- Severe inpatient hypertension prevalence and blood pressure response to antihypertensive treatment.Ghazi L, Li F, Chen X, Simonov M, Yamamoto Y, Biswas A, Hanna J, Shah T, Townsend R, Peixoto A, Wilson FP. Severe inpatient hypertension prevalence and blood pressure response to antihypertensive treatment. Journal Of Clinical Hypertension (Greenwich, Conn.) 2022, 24: 339-349. PMID: 35174627, PMCID: PMC8925013, DOI: 10.1111/jch.14431.
- Sample size calculation in hierarchical 2 × 2 factorial trials with unequal cluster sizes.Tian Z, Esserman D, Tong G, Blaha O, Dziura J, Peduzzi P, Li F. Sample size calculation in hierarchical 2 × 2 factorial trials with unequal cluster sizes. Statistics In Medicine 2022, 41: 645-664. PMID: 34978097, PMCID: PMC8962918, DOI: 10.1002/sim.9284.
- Accounting for unequal cluster sizes in designing cluster randomized trials to detect treatment effect heterogeneity.Tong G, Esserman D, Li F. Accounting for unequal cluster sizes in designing cluster randomized trials to detect treatment effect heterogeneity. Statistics In Medicine 2022, 41: 1376-1396. PMID: 34923655, DOI: 10.1002/sim.9283.
- A Bayesian approach for estimating the partial potential impact fraction with exposure measurement error under a main study/internal validation design.Chen X, Chang J, Spiegelman D, Li F. A Bayesian approach for estimating the partial potential impact fraction with exposure measurement error under a main study/internal validation design. Statistical Methods In Medical Research 2022, 31: 404-418. PMID: 34841964, DOI: 10.1177/09622802211060514.
- Methodological challenges in pragmatic trials in Alzheimer's disease and related dementias: Opportunities for improvement.Taljaard M, Li F, Qin B, Cui C, Zhang L, Nicholls SG, Carroll K, Mitchell SL. Methodological challenges in pragmatic trials in Alzheimer's disease and related dementias: Opportunities for improvement. Clinical Trials (London, England) 2022, 19: 86-96. PMID: 34841910, PMCID: PMC8847324, DOI: 10.1177/17407745211046672.
- swdpwr: A SAS macro and an R package for power calculations in stepped wedge cluster randomized trials.Chen J, Zhou X, Li F, Spiegelman D. swdpwr: A SAS macro and an R package for power calculations in stepped wedge cluster randomized trials. Computer Methods And Programs In Biomedicine 2022, 213: 106522. PMID: 34818620, PMCID: PMC8665077, DOI: 10.1016/j.cmpb.2021.106522.
- Estimating the natural indirect effect and the mediation proportion via the product method.Cheng C, Spiegelman D, Li F. Estimating the natural indirect effect and the mediation proportion via the product method. BMC Medical Research Methodology 2021, 21: 253. PMID: 34800985, PMCID: PMC8606099, DOI: 10.1186/s12874-021-01425-4.
- Sample size considerations for stepped wedge designs with subclusters.Davis-Plourde K, Taljaard M, Li F. Sample size considerations for stepped wedge designs with subclusters. Biometrics 2021 PMID: 34719017, PMCID: PMC9054939, DOI: 10.1111/biom.13596.
- Impact of complex, partially nested clustering in a three-arm individually randomized group treatment trial: A case study with the wHOPE trial.Tong G, Seal KH, Becker WC, Li F, Dziura JD, Peduzzi PN, Esserman DA. Impact of complex, partially nested clustering in a three-arm individually randomized group treatment trial: A case study with the wHOPE trial. Clinical Trials (London, England) 2022, 19: 3-13. PMID: 34693748, PMCID: PMC8847260, DOI: 10.1177/17407745211051288.
- Impact of unequal cluster sizes for GEE analyses of stepped wedge cluster randomized trials with binary outcomes.Tian Z, Preisser JS, Esserman D, Turner EL, Rathouz PJ, Li F. Impact of unequal cluster sizes for GEE analyses of stepped wedge cluster randomized trials with binary outcomes. Biometrical Journal. Biometrische Zeitschrift 2022, 64: 419-439. PMID: 34596912, DOI: 10.1002/bimj.202100112.
- Marginal modeling of cluster-period means and intraclass correlations in stepped wedge designs with binary outcomes.Li F, Yu H, Rathouz PJ, Turner EL, Preisser JS. Marginal modeling of cluster-period means and intraclass correlations in stepped wedge designs with binary outcomes. Biostatistics (Oxford, England) 2021 PMID: 33527999, DOI: 10.1093/biostatistics/kxaa056.
- Estimating heterogeneous survival treatment effect in observational data using machine learning.Hu L, Ji J, Li F. Estimating heterogeneous survival treatment effect in observational data using machine learning. Statistics In Medicine 2021, 40: 4691-4713. PMID: 34114252, DOI: 10.1002/sim.9090.
- Mixed-effects models for the design and analysis of stepped wedge cluster randomized trials: An overview.Li F, Hughes JP, Hemming K, Taljaard M, Melnick ER, Heagerty PJ. Mixed-effects models for the design and analysis of stepped wedge cluster randomized trials: An overview. Statistical Methods In Medical Research 2021, 30: 612-639. PMID: 32631142, PMCID: PMC7785651, DOI: 10.1177/0962280220932962.
- Early identification of patients with acute gastrointestinal bleeding using natural language processing and decision rules.Shung D, Tsay C, Laine L, Chang D, Li F, Thomas P, Partridge C, Simonov M, Hsiao A, Tay JK, Taylor A. Early identification of patients with acute gastrointestinal bleeding using natural language processing and decision rules. Journal Of Gastroenterology And Hepatology 2021, 36: 1590-1597. PMID: 33105045, DOI: 10.1111/jgh.15313.
- Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trial.Wilson FP, Martin M, Yamamoto Y, Partridge C, Moreira E, Arora T, Biswas A, Feldman H, Garg AX, Greenberg JH, Hinchcliff M, Latham S, Li F, Lin H, Mansour SG, Moledina DG, Palevsky PM, Parikh CR, Simonov M, Testani J, Ugwuowo U. Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trial. BMJ (Clinical Research Ed.) 2021, 372: m4786. PMID: 33461986, PMCID: PMC8034420, DOI: 10.1136/bmj.m4786.
- Assessment of Acute Kidney Injury and Longitudinal Kidney Function After Hospital Discharge Among Patients With and Without COVID-19.Nugent J, Aklilu A, Yamamoto Y, Simonov M, Li F, Biswas A, Ghazi L, Greenberg J, Mansour S, Moledina D, Wilson FP. Assessment of Acute Kidney Injury and Longitudinal Kidney Function After Hospital Discharge Among Patients With and Without COVID-19. JAMA Network Open 2021, 4: e211095. PMID: 33688965, PMCID: PMC7948062, DOI: 10.1001/jamanetworkopen.2021.1095.
- Covariate adjustment in subgroup analyses of randomized clinical trials: A propensity score approach.Yang S, Li F, Thomas LE, Li F. Covariate adjustment in subgroup analyses of randomized clinical trials: A propensity score approach. Clinical Trials (London, England) 2021, 18: 570-581. PMID: 34269087, DOI: 10.1177/17407745211028588.
- Sample size and power considerations for cluster randomized trials with count outcomes subject to right truncation.Li F, Tong G. Sample size and power considerations for cluster randomized trials with count outcomes subject to right truncation. Biometrical Journal. Biometrische Zeitschrift 2021, 63: 1052-1071. PMID: 33751620, DOI: 10.1002/bimj.202000230.
- Propensity score weighting for covariate adjustment in randomized clinical trials.Zeng S, Li F, Wang R, Li F. Propensity score weighting for covariate adjustment in randomized clinical trials. Statistics In Medicine 2021, 40: 842-858. PMID: 33174296, DOI: 10.1002/sim.8805.
- Sample size estimation for modified Poisson analysis of cluster randomized trials with a binary outcome.Li F, Tong G. Sample size estimation for modified Poisson analysis of cluster randomized trials with a binary outcome. Statistical Methods In Medical Research 2021, 30: 1288-1305. PMID: 33826454, DOI: 10.1177/0962280221990415.
- Nanoparticle-mediated convection-enhanced delivery of a DNA intercalator to gliomas circumvents temozolomide resistance.Wang Y, Jiang Y, Wei D, Singh P, Yu Y, Lee T, Zhang L, Mandl HK, Piotrowski-Daspit AS, Chen X, Li F, Li X, Cheng Y, Josowitz A, Yang F, Zhao Y, Wang F, Zhao Z, Huttner A, Bindra RS, Xiao H, Mark Saltzman W. Nanoparticle-mediated convection-enhanced delivery of a DNA intercalator to gliomas circumvents temozolomide resistance. Nature Biomedical Engineering 2021, 5: 1048-1058. PMID: 34045730, PMCID: PMC8497438, DOI: 10.1038/s41551-021-00728-7.
- Bayesian estimation of genetic regulatory effects in high-throughput reporter assays.Majoros WH, Kim YS, Barrera A, Li F, Wang X, Cunningham SJ, Johnson GD, Guo C, Lowe WL, Scholtens DM, Hayes MG, Reddy TE, Allen AS. Bayesian estimation of genetic regulatory effects in high-throughput reporter assays. Bioinformatics (Oxford, England) 2020, 36: 331-338. PMID: 31368479, PMCID: PMC7999138, DOI: 10.1093/bioinformatics/btz545.
- The uptick in income segregation: Real trend or random sampling variation?Logan J, Foster A, Ke J, Li F. The uptick in income segregation: Real trend or random sampling variation? American Journal of Sociology 2018,124:185-222.
- Properties and pitfalls of weighting as an alternative to multilevel multiple imputation in cluster randomized trials with missing binary outcomes under covariate-dependent missingness.Turner EL, Yao L, Li F, Prague M. Properties and pitfalls of weighting as an alternative to multilevel multiple imputation in cluster randomized trials with missing binary outcomes under covariate-dependent missingness. Statistical Methods In Medical Research 2020, 29: 1338-1353. PMID: 31293199, DOI: 10.1177/0962280219859915.
- Design and analysis considerations for cohort stepped wedge cluster randomized trials with a decay correlation structure.Li F. Design and analysis considerations for cohort stepped wedge cluster randomized trials with a decay correlation structure. Statistics In Medicine 2020, 39: 438-455. PMID: 31797438, PMCID: PMC7027591, DOI: 10.1002/sim.8415.
- Secondary analysis of case-control association studies: Insights on weighting-based inference motivate a new specification test.Li F, Allen AS. Secondary analysis of case-control association studies: Insights on weighting-based inference motivate a new specification test. Statistics In Medicine 2020, 39: 2869-2882. PMID: 32501597, DOI: 10.1002/sim.8579.
- Commentary: Right truncation in cluster randomized trials can attenuate the power of a marginal analysis.Li F, Harhay MO. Commentary: Right truncation in cluster randomized trials can attenuate the power of a marginal analysis. International Journal Of Epidemiology 2020, 49: 964-967. PMID: 32211886, PMCID: PMC7394942, DOI: 10.1093/ije/dyaa037.
- An evidence mapping and analysis of registered COVID-19 clinical trials in China.Lu L, Li F, Wen H, Ge S, Zeng J, Luo W, Wang L, Tang C, Xu N. An evidence mapping and analysis of registered COVID-19 clinical trials in China. BMC Medicine 2020, 18: 167. PMID: 32493331, PMCID: PMC7268588, DOI: 10.1186/s12916-020-01612-y.
- Double-robust estimation in difference-in-differences with an application to traffic safety evaluationLi F, Li F. Double-robust estimation in difference-in-differences with an application to traffic safety evaluation. Observational Studies 2019,5:1-20.
- Statistical Considerations for Embedded Pragmatic Clinical Trials in People Living with Dementia.Allore HG, Goldfeld KS, Gutman R, Li F, Monin JK, Taljaard M, Travison TG. Statistical Considerations for Embedded Pragmatic Clinical Trials in People Living with Dementia. Journal Of The American Geriatrics Society 2020, 68 Suppl 2: S68-S73. PMID: 32589276, PMCID: PMC7396162, DOI: 10.1111/jgs.16616.
- An evaluation of quadratic inference functions for estimating intervention effects in cluster randomized trials.Yu H, Li F, Turner EL. An evaluation of quadratic inference functions for estimating intervention effects in cluster randomized trials. Contemporary Clinical Trials Communications 2020, 19: 100605. PMID: 32728648, PMCID: PMC7381491, DOI: 10.1016/j.conctc.2020.100605.
- Sample size requirements for detecting treatment effect heterogeneity in cluster randomized trials.Yang S, Li F, Starks MA, Hernandez AF, Mentz RJ, Choudhury KR. Sample size requirements for detecting treatment effect heterogeneity in cluster randomized trials. Statistics In Medicine 2020, 39: 4218-4237. PMID: 32823372, PMCID: PMC7948251, DOI: 10.1002/sim.8721.
- Power and sample size requirements for GEE analyses of cluster randomized crossover trials.Li F, Forbes AB, Turner EL, Preisser JS. Power and sample size requirements for GEE analyses of cluster randomized crossover trials. Statistics In Medicine 2019, 38: 636-649. PMID: 30298551, PMCID: PMC6461037, DOI: 10.1002/sim.7995.
- Addressing Extreme Propensity Scores via the Overlap Weights.Li F, Thomas LE, Li F. Addressing Extreme Propensity Scores via the Overlap Weights. American Journal Of Epidemiology 2019, 188: 250-257. PMID: 30189042, DOI: 10.1093/aje/kwy201.
- Predicting the Risk of Huntington's Disease with Multiple Longitudinal Biomarkers.Li F, Li K, Li C, Luo S. Predicting the Risk of Huntington's Disease with Multiple Longitudinal Biomarkers. Journal Of Huntington's Disease 2019, 8: 323-332. PMID: 31256145, PMCID: PMC6718328, DOI: 10.3233/JHD-190345.
- Genetic Polymorphisms of CFH and ARMS2 Do Not Predict Response to Antioxidants and Zinc in Patients with Age-Related Macular Degeneration: Independent Statistical Evaluations of Data from the Age-Related Eye Disease Study.Assel MJ, Li F, Wang Y, Allen AS, Baggerly KA, Vickers AJ. Genetic Polymorphisms of CFH and ARMS2 Do Not Predict Response to Antioxidants and Zinc in Patients with Age-Related Macular Degeneration: Independent Statistical Evaluations of Data from the Age-Related Eye Disease Study. Ophthalmology 2018, 125: 391-397. PMID: 29032853, PMCID: PMC5820191, DOI: 10.1016/j.ophtha.2017.09.008.
- Bayesian Word Learning in Multiple Language Environments.Zinszer BD, Rolotti SV, Li F, Li P. Bayesian Word Learning in Multiple Language Environments. Cognitive Science 2018, 42 Suppl 2: 439-462. PMID: 29154481, DOI: 10.1111/cogs.12567.
- Sample size determination for GEE analyses of stepped wedge cluster randomized trials.Li F, Turner EL, Preisser JS. Sample size determination for GEE analyses of stepped wedge cluster randomized trials. Biometrics 2018, 74: 1450-1458. PMID: 29921006, PMCID: PMC6461045, DOI: 10.1111/biom.12918.
- An evaluation of constrained randomization for the design and analysis of group-randomized trials with binary outcomes.Li F, Turner EL, Heagerty PJ, Murray DM, Vollmer WM, DeLong ER. An evaluation of constrained randomization for the design and analysis of group-randomized trials with binary outcomes. Statistics In Medicine 2017, 36: 3791-3806. PMID: 28786223, PMCID: PMC5624845, DOI: 10.1002/sim.7410.
- An evaluation of constrained randomization for the design and analysis of group-randomized trials.Li F, Lokhnygina Y, Murray DM, Heagerty PJ, DeLong ER. An evaluation of constrained randomization for the design and analysis of group-randomized trials. Statistics In Medicine 2016, 35: 1565-79. PMID: 26598212, PMCID: PMC4826850, DOI: 10.1002/sim.6813.
- Transcatheter Versus Surgical Aortic Valve Replacement: Propensity-Matched Comparison.Brennan JM, Thomas L, Cohen DJ, Shahian D, Wang A, Mack MJ, Holmes DR, Edwards FH, Frankel NZ, Baron SJ, Carroll J, Thourani V, Tuzcu EM, Arnold SV, Cohn R, Maser T, Schawe B, Strong S, Stickfort A, Patrick-Lake E, Graham FL, Dai D, Li F, Matsouaka RA, O'Brien S, Li F, Pencina MJ, Peterson ED. Transcatheter Versus Surgical Aortic Valve Replacement: Propensity-Matched Comparison. Journal Of The American College Of Cardiology 2017, 70: 439-450. PMID: 28728688, PMCID: PMC5826727, DOI: 10.1016/j.jacc.2017.05.060.
- Review of Recent Methodological Developments in Group-Randomized Trials: Part 1-Design.Turner EL, Li F, Gallis JA, Prague M, Murray DM. Review of Recent Methodological Developments in Group-Randomized Trials: Part 1-Design. American Journal Of Public Health 2017, 107: 907-915. PMID: 28426295, PMCID: PMC5425852, DOI: 10.2105/AJPH.2017.303706.
- Review of Recent Methodological Developments in Group-Randomized Trials: Part 2-Analysis.Turner EL, Prague M, Gallis JA, Li F, Murray DM. Review of Recent Methodological Developments in Group-Randomized Trials: Part 2-Analysis. American Journal Of Public Health 2017, 107: 1078-1086. PMID: 28520480, PMCID: PMC5463203, DOI: 10.2105/AJPH.2017.303707.
- Comparative Evaluation of a South Carolina Policy to Improve Nutrition in Child Care.Benjamin Neelon SE, Mayhew M, O'Neill JR, Neelon B, Li F, Pate RR. Comparative Evaluation of a South Carolina Policy to Improve Nutrition in Child Care. Journal Of The Academy Of Nutrition And Dietetics 2016, 116: 949-56. PMID: 26777469, DOI: 10.1016/j.jand.2015.10.026.
- A spatiotemporal quantile regression model for emergency department expenditures.Neelon B, Li F, Burgette LF, Neelon SE. A spatiotemporal quantile regression model for emergency department expenditures. Statistics In Medicine 2015, 34: 2559-75. PMID: 25782041, DOI: 10.1002/sim.6480.