Eric Nunes, PhD
Research Scientist in Psychiatry
Research & Publications
Biography
News
Coauthors
Selected Publications
- Targeting the Actions of Muscarinic Receptors on Dopamine Systems: New Strategies for Treating Neuropsychiatric DisordersNunes E, Addy N, Conn P, Foster D. Targeting the Actions of Muscarinic Receptors on Dopamine Systems: New Strategies for Treating Neuropsychiatric Disorders. The Annual Review Of Pharmacology And Toxicology 2023, 64: 277-289. PMID: 37552895, PMCID: PMC10841102, DOI: 10.1146/annurev-pharmtox-051921-023858.
- Ventral tegmental area M5 muscarinic receptors mediate effort-choice responding and nucleus accumbens dopamine in a sex-specific mannerNunes E, Kebede N, Haight J, Foster D, Lindsley C, Conn P, Addy N. Ventral tegmental area M5 muscarinic receptors mediate effort-choice responding and nucleus accumbens dopamine in a sex-specific manner. Journal Of Pharmacology And Experimental Therapeutics 2023, 385: jpet-ar-2022-001438. PMID: 36828630, PMCID: PMC10108441, DOI: 10.1124/jpet.122.001438.
- L-type calcium channel regulation of dopamine activity in the ventral tegmental area to nucleus accumbens pathway: Implications for substance use, mood disorders and co-morbiditiesNunes E, Addy N. L-type calcium channel regulation of dopamine activity in the ventral tegmental area to nucleus accumbens pathway: Implications for substance use, mood disorders and co-morbidities. Neuropharmacology 2022, 224: 109336. PMID: 36414149, DOI: 10.1016/j.neuropharm.2022.109336.
- Cholinergic and dopaminergic‐mediated motivated behavior in healthy states and in substance use and mood disordersNunes EJ, Kebede N, Bagdas D, Addy NA. Cholinergic and dopaminergic‐mediated motivated behavior in healthy states and in substance use and mood disorders. Journal Of The Experimental Analysis Of Behavior 2022, 117: 404-419. PMID: 35286712, PMCID: PMC9743782, DOI: 10.1002/jeab.747.
- Evaluation of Flavor Effects on Oral Nicotine Liking and/or Disliking Using the Taste Reactivity Test in Rats.Bagdas D, Rupprecht LE, Nunes EJ, Schillinger E, Immanuel JJ, Addy NA. Evaluation of Flavor Effects on Oral Nicotine Liking and/or Disliking Using the Taste Reactivity Test in Rats. Nicotine & Tobacco Research 2021, 24: 753-760. PMID: 34918123, PMCID: PMC8962681, DOI: 10.1093/ntr/ntab241.
- Dopamine/Adenosine Interactions Related to Tremor in Animal Models of ParkinsonismSalamone J, Podurgiel S, Long L, Nunes E, Correa M. Dopamine/Adenosine Interactions Related to Tremor in Animal Models of Parkinsonism. 2015, 10: 149-162. DOI: 10.1007/978-3-319-20273-0_8.
- Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake RatsWickham R, Park J, Nunes E, Addy N. Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats. Journal Of Visualized Experiments 2015 DOI: 10.3791/52468-v.
- The VMAT-2 Inhibitor Tetrabenazine Affects Effort-Related Decision Making in a Progressive Ratio/Chow Feeding Choice Task: Reversal with Antidepressant DrugsRandall P, Lee C, Nunes E, Yohn S, Nowak V, Khan B, Shah P, Pandit S, Vemuri V, Makriyannis A, Baqi Y, Müller C, Correa M, Salamone J. The VMAT-2 Inhibitor Tetrabenazine Affects Effort-Related Decision Making in a Progressive Ratio/Chow Feeding Choice Task: Reversal with Antidepressant Drugs. PLOS ONE 2014, 9: e99320. PMID: 24937131, PMCID: PMC4061002, DOI: 10.1371/journal.pone.0099320.
- Effort-Related Motivational Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Animal Models of the Motivational Symptoms of DepressionNunes E, Randall P, Hart E, Freeland C, Yohn S, Baqi Y, Müller C, López-Cruz L, Correa M, Salamone J. Effort-Related Motivational Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Animal Models of the Motivational Symptoms of Depression. Journal Of Neuroscience 2013, 33: 19120-19130. PMID: 24305809, PMCID: PMC3850037, DOI: 10.1523/jneurosci.2730-13.2013.
- Effort-related motivational effects of the pro-inflammatory cytokine interleukin 1-beta: studies with the concurrent fixed ratio 5/ chow feeding choice taskNunes E, Randall P, Estrada A, Epling B, Hart E, Lee C, Baqi Y, Müller C, Correa M, Salamone J. Effort-related motivational effects of the pro-inflammatory cytokine interleukin 1-beta: studies with the concurrent fixed ratio 5/ chow feeding choice task. Psychopharmacology 2013, 231: 727-736. PMID: 24136220, PMCID: PMC4468782, DOI: 10.1007/s00213-013-3285-4.
- S.2.1 - DEVELOPMENT OF ANIMAL MODELS OF THE EFFORT-RELATED SYMPTOMS OF DEPRESSIONSalamone J, Nunes E, Randall P, Yohn S, Merce C. S.2.1 - DEVELOPMENT OF ANIMAL MODELS OF THE EFFORT-RELATED SYMPTOMS OF DEPRESSION. Behavioural Pharmacology 2013, 24: e3. DOI: 10.1097/01.fbp.0000434686.35248.7a.
- The vesicular monoamine transporter (VMAT-2) inhibitor tetrabenazine induces tremulous jaw movements in rodents: Implications for pharmacological models of parkinsonian tremorPodurgiel S, Nunes E, Yohn S, Barber J, Thompson A, Milligan M, Lee C, López-Cruz L, Pardo M, Valverde O, Lendent C, Baqi Y, Müller C, Correa M, Salamone J. The vesicular monoamine transporter (VMAT-2) inhibitor tetrabenazine induces tremulous jaw movements in rodents: Implications for pharmacological models of parkinsonian tremor. Neuroscience 2013, 250: 507-519. PMID: 23867769, DOI: 10.1016/j.neuroscience.2013.07.008.
- Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: Effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptorsNunes E, Randall P, Podurgiel S, Correa M, Salamone J. Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: Effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors. Neuroscience & Biobehavioral Reviews 2013, 37: 2015-2025. PMID: 23583616, DOI: 10.1016/j.neubiorev.2013.04.002.
- Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual DifferencesRandall P, Pardo M, Nunes E, Cruz L, Vemuri V, Makriyannis A, Baqi Y, Müller C, Correa M, Salamone J. Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences. PLOS ONE 2012, 7: e47934. PMID: 23110135, PMCID: PMC3478264, DOI: 10.1371/journal.pone.0047934.
- The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of MotivationSalamone J, Correa M, Randall P, Nunes E, Pardo M, Lopez-Cruz L. The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation. 2012, 493-512. DOI: 10.1007/978-1-4614-3903-5_23.
- The novel adenosine A2A antagonist prodrug MSX-4 is effective in animal models related to motivational and motor functionsSanterre J, Nunes E, Kovner R, Leser C, Randall P, Collins-Praino L, Cruz L, Correa M, Baqi Y, Müller C, Salamone J. The novel adenosine A2A antagonist prodrug MSX-4 is effective in animal models related to motivational and motor functions. Pharmacology Biochemistry And Behavior 2012, 102: 477-487. PMID: 22705392, DOI: 10.1016/j.pbb.2012.06.009.
- THE BEHAVIORAL PHARMACOLOGY OF EFFORT‐RELATED CHOICE BEHAVIOR: DOPAMINE, ADENOSINE AND BEYONDSalamone J, Correa M, Nunes E, Randall P, Pardo M. THE BEHAVIORAL PHARMACOLOGY OF EFFORT‐RELATED CHOICE BEHAVIOR: DOPAMINE, ADENOSINE AND BEYOND. Journal Of The Experimental Analysis Of Behavior 2012, 97: 125-146. PMID: 22287808, PMCID: PMC3266736, DOI: 10.1901/jeab.2012.97-125.
- Stimulant effects of adenosine antagonists on operant behavior: differential actions of selective A2A and A1 antagonistsRandall P, Nunes E, Janniere S, Stopper C, Farrar A, Sager T, Baqi Y, Hockemeyer J, Müller C, Salamone J. Stimulant effects of adenosine antagonists on operant behavior: differential actions of selective A2A and A1 antagonists. Psychopharmacology 2011, 216: 173-186. PMID: 21347642, PMCID: PMC3522121, DOI: 10.1007/s00213-011-2198-3.
- The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behaviorRandall P, Vemuri V, Segovia K, Torres E, Hosmer S, Nunes E, Santerre J, Makriyannis A, Salamone J. The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior. Pharmacology Biochemistry And Behavior 2010, 97: 179-184. PMID: 20713079, PMCID: PMC3522179, DOI: 10.1016/j.pbb.2010.07.021.
- Differential effects of selective adenosine antagonists on the effort-related impairments induced by dopamine D1 and D2 antagonismNunes E, Randall P, Santerre J, Given A, Sager T, Correa M, Salamone J. Differential effects of selective adenosine antagonists on the effort-related impairments induced by dopamine D1 and D2 antagonism. Neuroscience 2010, 170: 268-280. PMID: 20600675, PMCID: PMC3268040, DOI: 10.1016/j.neuroscience.2010.05.068.
- Role of dopamineadenosine interactions in the brain circuitry regulating effort-related decision making: insights into pathological aspects of motivationSalamone J, Correa M, Farrar A, Nunes E, Collins L. Role of dopamineadenosine interactions in the brain circuitry regulating effort-related decision making: insights into pathological aspects of motivation. Future Neurology 2010, 5: 377-392. DOI: 10.2217/fnl.10.19.
- Nucleus accumbens and effort-related functions: behavioral and neural markers of the interactions between adenosine A2A and dopamine D2 receptorsFarrar A, Segovia K, Randall P, Nunes E, Collins L, Stopper C, Port R, Hockemeyer J, Müller C, Correa M, Salamone J. Nucleus accumbens and effort-related functions: behavioral and neural markers of the interactions between adenosine A2A and dopamine D2 receptors. Neuroscience 2010, 166: 1056-1067. PMID: 20096336, DOI: 10.1016/j.neuroscience.2009.12.056.
- Dopamine, Behavioral Economics, and EffortSalamone J, Correa M, Farrar A, Nunes E, Pardo M. Dopamine, Behavioral Economics, and Effort. Frontiers In Behavioral Neuroscience 2009, 3: 13. PMID: 19826615, PMCID: PMC2759361, DOI: 10.3389/neuro.08.013.2009.
- Intracerebroventricular administration of cannabinoid CB1 receptor antagonists AM251 and AM4113 fails to alter food-reinforced behavior in ratsSink K, Segovia K, Nunes E, Collins L, Vemuri V, Thakur G, Makriyannis A, Salamone J. Intracerebroventricular administration of cannabinoid CB1 receptor antagonists AM251 and AM4113 fails to alter food-reinforced behavior in rats. Psychopharmacology 2009, 206: 223-232. PMID: 19588124, PMCID: PMC4425366, DOI: 10.1007/s00213-009-1602-8.
- Differential actions of adenosine A1 and A2A antagonists on the effort-related effects of dopamine D2 antagonismSalamone J, Farrar A, Font L, Patel V, Schlar D, Nunes E, Collins L, Sager T. Differential actions of adenosine A1 and A2A antagonists on the effort-related effects of dopamine D2 antagonism. Behavioural Brain Research 2009, 201: 216-222. PMID: 19428636, PMCID: PMC2806666, DOI: 10.1016/j.bbr.2009.02.021.
- The adenosine A2A antagonist MSX-3 reverses the effects of the dopamine antagonist haloperidol on effort-related decision making in a T-maze cost/benefit procedureMott A, Nunes E, Collins L, Port R, Sink K, Hockemeyer J, Müller C, Salamone J. The adenosine A2A antagonist MSX-3 reverses the effects of the dopamine antagonist haloperidol on effort-related decision making in a T-maze cost/benefit procedure. Psychopharmacology 2009, 204: 103. PMID: 19132351, PMCID: PMC2875244, DOI: 10.1007/s00213-008-1441-z.