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Elsio Wunder Jr

Research Scientist in Epidemiology (Microbial Diseases); Lecturer - Water, Sanitation and Public Health, EMD; Affiliated Faculty, Yale Institute for Global Health

Contact Information

Elsio Wunder Jr, PhD, MS, DVM

Lab Location

Office Location

Mailing Address

  • Epidemiology of Microbial Diseases

    60 College Street, LEPH 319A

    New Haven, CT 06510

    United States

Research Summary

  • Pathogenesis of leptospirosis
  • Vaccine development for leptospirosis
  • Natural-acquired immunity against Leptospira infection
  • Motility of the spirochete Leptospira spp.
  • Clinical diagnostic of leptospirosis

Extensive Research Description

Dr. Wunder has an extensive research experience in Brazil and the US working on the pathogenesis of Leptospira sp. and vaccine development. His research is focused on understanding the pathogenesis of leptospirosis, and, more specifically, identifying virulence factors in the spirochetal pathogen, which may in turn serve as the basis for novel approaches for diagnostics and vaccines.

Currently he is evaluating the hamster immune response to immunization with an attenuated Leptospira strain, to identify potential protein candidates for subunit vaccine design. More recent his work has been focus also on understanding the motility of the pathogen and its ability to penetrate and disseminate within host-tissues.


Research Interests

Leptospira; Leptospirosis; Vaccines, Attenuated; Host-Pathogen Interactions; Translational Research, Biomedical

Public Health Interests

Disease Transmission; Global Health; Infectious Diseases; Zoonotic Diseases

Research Image

Selected Publications