Ellen J. Hoffman, MD, PhD

• Abha Gupta
• Adife Ercan-Sencicek
• Antonio Giraldez
• James Noonan
• Matthew State
• Nenad Sestan
• Rebecca Muhle
• Shrikant Mane
• Sofia Fertuzinhos
• Steven Reilly

Autistic Disorder; Child Psychiatry; Genetics; Neurobiology; Neuropharmacology; Neurosciences; Pharmacology; Zebrafish; Translational Medical Research

• Progress in cytogenetics: implications for child psychopathology.Hoffman EJ, State MW. Progress in cytogenetics: implications for child psychopathology. Journal Of The American Academy Of Child And Adolescent Psychiatry 2010, 49: 736-51; quiz 856-7. PMID: 20643309, DOI: 10.1016/j.jaac.2010.03.016.
• Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).Sander JD, Dahlborg EJ, Goodwin MJ, Cade L, Zhang F, Cifuentes D, Curtin SJ, Blackburn JS, Thibodeau-Beganny S, Qi Y, Pierick CJ, Hoffman E, Maeder ML, Khayter C, Reyon D, Dobbs D, Langenau DM, Stupar RM, Giraldez AJ, Voytas DF, Peterson RT, Yeh JR, Joung JK. Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA). Nature Methods 2011, 8: 67-9. PMID: 21151135, PMCID: PMC3018472, DOI: 10.1038/nmeth.1542.
• Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: efficient identification of known microduplications and identification of a novel microduplication in ASMT.Cai G, Edelmann L, Goldsmith JE, Cohen N, Nakamine A, Reichert JG, Hoffman EJ, Zurawiecki DM, Silverman JM, Hollander E, Soorya L, Anagnostou E, Betancur C, Buxbaum JD. Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: efficient identification of known microduplications and identification of a novel microduplication in ASMT. BMC Medical Genomics 2008, 1: 50. PMID: 18925931, PMCID: PMC2588447, DOI: 10.1186/1755-8794-1-50.
• A large-scale screen for coding variants in SERT/SLC6A4 in autism spectrum disorders.Sakurai T, Reichert J, Hoffman EJ, Cai G, Jones HB, Faham M, Buxbaum JD. A large-scale screen for coding variants in SERT/SLC6A4 in autism spectrum disorders. Autism Research : Official Journal Of The International Society For Autism Research 2008, 1: 251-7. PMID: 19360675, PMCID: PMC2678895, DOI: 10.1002/aur.30.
• Effects of ethanol on axon outgrowth and branching in developing rat cortical neurons.Hoffman EJ, Mintz CD, Wang S, McNickle DG, Salton SR, Benson DL. Effects of ethanol on axon outgrowth and branching in developing rat cortical neurons. Neuroscience 2008, 157: 556-65. PMID: 18926887, PMCID: PMC2626542, DOI: 10.1016/j.neuroscience.2008.08.071.
• Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2.Hoffman EJ, Turner KJ, Fernandez JM, Cifuentes D, Ghosh M, Ijaz S, Jain RA, Kubo F, Bill BR, Baier H, Granato M, Barresi MJ, Wilson SW, Rihel J, State MW, Giraldez AJ. Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2. Neuron 2016, 89: 725-33. PMID: 26833134, PMCID: PMC4766582, DOI: 10.1016/j.neuron.2015.12.039.
• Zebrafish: A Translational Model System for Studying Neuropsychiatric Disorders.Ijaz S, Hoffman EJ. Zebrafish: A Translational Model System for Studying Neuropsychiatric Disorders. Journal Of The American Academy Of Child And Adolescent Psychiatry 2016, 55: 746-8. PMID: 27566113, PMCID: PMC5521170, DOI: 10.1016/j.jaac.2016.06.008.
• Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism.Willsey AJ, Sanders SJ, Li M, Dong S, Tebbenkamp AT, Muhle RA, Reilly SK, Lin L, Fertuzinhos S, Miller JA, Murtha MT, Bichsel C, Niu W, Cotney J, Ercan-Sencicek AG, Gockley J, Gupta AR, Han W, He X, Hoffman EJ, Klei L, Lei J, Liu W, Liu L, Lu C, Xu X, Zhu Y, Mane SM, Lein ES, Wei L, Noonan JP, Roeder K, Devlin B, Sestan N, State MW. Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell 2013, 155: 997-1007. PMID: 24267886, PMCID: PMC3995413, DOI: 10.1016/j.cell.2013.10.020.