Edwin Siu, MS

• Ben-Hua Sun
• Erol Fikrig
• Gang-Qing Yao
• Karl Insogna
• Lin Leng
• Richard Bucala

Bone and Bones; Bone Diseases, Endocrine; Bone Diseases, Metabolic; Osteoporosis; Biomedical Research

• An Unanticipated Role for Sphingosine Kinase-2 in Bone and in the Anabolic Effect of Parathyroid Hormone.Walker JM, Yao GQ, Siu E, Zhu M, Sun BH, Simpson C, Insogna KL. An Unanticipated Role for Sphingosine Kinase-2 in Bone and in the Anabolic Effect of Parathyroid Hormone. Endocrinology 2021, 162 PubMed ID: 33640975, PMCID: PMC8095390, DOI: 10.1210/endocr/bqab042.
• Genotyping Two Promoter Polymorphisms in the MIF Gene: A -794 CATT5-8 Microsatellite Repeat and a -173 G/C SNP.Leng L, Siu E, Bucala R. Genotyping Two Promoter Polymorphisms in the MIF Gene: A -794 CATT5-8 Microsatellite Repeat and a -173 G/C SNP. Methods In Molecular Biology (Clifton, N.J.) 2020, 2080: 67-84 PubMed ID: 31745872, DOI: 10.1007/978-1-4939-9936-1_7.
• Macrophage migration inhibitory factor regulates innate γδ T-cell responses via IL-17 expression.Kim HK, Garcia AB, Siu E, Tilstam P, Das R, Roberts S, Leng L, Bucala R. Macrophage migration inhibitory factor regulates innate γδ T-cell responses via IL-17 expression. FASEB Journal : Official Publication Of The Federation Of American Societies For Experimental Biology 2019, 33: 6919-6932 PubMed ID: 30817226, PMCID: PMC6529351, DOI: 10.1096/fj.201802433R.
• Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection.Baeza Garcia A, Siu E, Sun T, Exler V, Brito L, Hekele A, Otten G, Augustijn K, Janse CJ, Ulmer JB, Bernhagen J, Fikrig E, Geall A, Bucala R. Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection. Nature Communications 2018, 9: 2714 PubMed ID: 30006528, PMCID: PMC6045615, DOI: 10.1038/s41467-018-05041-7.
• MIF and D-DT are potential disease severity modifiers in male MS subjects.Benedek G, Meza-Romero R, Jordan K, Zhang Y, Nguyen H, Kent G, Li J, Siu E, Frazer J, Piecychna M, Du X, Sreih A, Leng L, Wiedrick J, Caillier SJ, Offner H, Oksenberg JR, Yadav V, Bourdette D, Bucala R, Vandenbark AA. MIF and D-DT are potential disease severity modifiers in male MS subjects. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: E8421-E8429 PubMed ID: 28923927, PMCID: PMC5635923, DOI: 10.1073/pnas.1712288114.
• Direct evidence for the adaptive role of copy number variation on antifolate susceptibility in Plasmodium falciparum.Heinberg A, Siu E, Stern C, Lawrence EA, Ferdig MT, Deitsch KW, Kirkman LA. Direct evidence for the adaptive role of copy number variation on antifolate susceptibility in Plasmodium falciparum. Molecular Microbiology 2013, 88: 702-12 PubMed ID: 23347134, PMCID: PMC3654098, DOI: 10.1111/mmi.12162.