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Eda Cengiz

MD, MHS, FAAP
Associate Professor of Pediatrics (Endocrinology)

Contact Information

Eda Cengiz, MD, MHS, FAAP

Mailing Address

  • Pediatric Endocrinology & Diabetes

    PO Box 208064

    New Haven, CT, 06520-8064

    United States

Research Summary

  • Pharmacokinetics & pharmacodynamics of insulin therapy;
  • Artificial Pancreas Project (APP);
  • Preservation of beta cells for children with new onset type 1 diabetes;
  • Type 1 Diabetes Exchnage and Pediatric Diabetes Consortium (PDC) project: building a database to monitor diabetes management and complications;
  • Integrating technology with diabetes care: use of new high-tech devices and methods to improve insulin delivery and function;
  • Detecting early cardiovascular disease markers for children and adolescents with type 1 diabetes.

Extensive Research Description

  • Closed loop insulin delivery system
  • Clamp studies to demonstrate pharmacokinetics and pharmacodynamics of insulin
  • Detecting early cardiovascular disease markers for children with type 1 diabetes including peripheral arterial tonometry
  • Pediatric Diabetes Consortium:utilizing a database registry to assess treatment approaches for children and youth with new-onset type 1 diabetes
  • Anti -CD3 treatment for preservation of beta cells in children with new onset type 1 diabetes
  • Artificial pancreas project
  • PKPD of insulin therapy
  • Pediatric Diabetes Consortium
  • Glucose sensor studies
  • Effect of the Human Recombinant Hyaluronidase (rHuPH20) on the Pharmacokinetic & Pharmacodynamic (PK/PD) Properties of Lispro and Aspart Insulin using the Euglycemic Clamp and on Meal-related Glucose Excursions during Open- and Closed-loop Insulin Delivery.

Coauthors

Research Interests

Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetes Complications

Selected Publications

Clinical Trials

ConditionsStudy Title
Diabetes Mellitus - Type 1; Diseases of the Endocrine System; Diseases of the Nervous SystemImpact of Hypoglycemia on Brain Ketone and Neurotransmitter Metabolism in Type 1 DM