Denis Sukhodolsky, PhD
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Research Summary
Denis Sukhodolsky is an Associate Professor in the Yale Child Study Center. His research concerns the efficacy and biomarkers of behavioral interventions for children with autism spectrum disorder, irritability, and related neurodevelopmental disorders. This work has been supported by grants from NIMH, NICHD, DoD CDMRP, and Simons Foundation. Currently, he is a principal investigator of clinical trials of behavior therapy for anxiety in school-age children with autism and another clinical trial of behavior therapy for irritability and aggressive behavior in adolescents with autism. He is also a Yale site PI of the ACE network study of gender differences and neural signatures of optimal outcomes in ASD during adolescence and young adulthood. In addition to his research, Dr. Sukhodolsky is a licensed and board-certified clinical psychologist working with children and their families at the Yale Child Study Center.
Extensive Research Description
Behavior therapy for irritability and aggression in adolescents with autism (AR190136). This clinical trial will test the effectiveness of a novel behavioral intervention for irritability and aggression (BTIA) in adolescents with autism complicated by disruptive behaviors such as anger outbursts and low frustration tolerance. BTIA consists of 15 ninety-minute weekly sessions that are conducted with the teens and their parents by experienced therapists. The goal of BTIA is to help adolescents on the autism spectrum acquire emotion regulation and problem-solving strategies for managing frustration. Funded by the Department of Defense Congressionally Directed Medical Research Program, this 4-year clinical trial will enroll 126 participants in the age range from 12 to 18 years with a diagnosis of autism spectrum disorder (ASD) and co-occurring behavioral difficulties. Study participants are randomly assigned to BTIA or a supportive psychotherapy control condition and outcome measures are conducted before, during and after treatment by a blinded rater.
Neural mechanisms of CBT for anxiety in autism (R01 HD083881). This is a randomized controlled trial of cognitive-behavior therapy (CBT) versus Psychological education and Supportive Therapy (PST) for anxiety in children, ages 8 to 14, with autism and moderate to severe anxiety. The study utilizes fMRI to identify CBT-invoked changes in levels of activity/functional connectivity within the neural circuits involved in emotion regulation and social perception.
Translating neuroprediction into precision medicine via brain priming (SFARI # 514534). This is a randomized controlled trial of Pivotal Response Training (PRT) with or without intranasal oxytocin in 5-to-9-year-old children on the autism spectrum. The study tests if oxytocin can create a neural background for individuals with ASD that can bolster their motivation to interact socially and facilitate their biological preparedness for learning social communication skills during behavioral treatments.
Multimodal developmental neurogenetics of females with ASD (R01 MH100028). This is a multi-site, longitudinal study of sex differences in ASD at the levels of gene structure and expression, neural dynamics, brain function and connectivity. The ACE network has curated an unprecedented sex-balanced, age-, IQ- and severity-matched cohort of cognitively-able school-age boys and girls with ASD, and age- and IQ-matched typically developing children and unaffected siblings. The second five-year period of this ACE network study is conducted to understand neurodevelopmental sex differences in ASD during transition to adulthood.
Coauthors
Research Interests
Aggression; Anger; Autistic Disorder; Behavior Therapy; Tourette Syndrome; Obsessive-Compulsive Disorder; Psychotherapy; Attention Deficit and Disruptive Behavior Disorders
Selected Publications
- A Randomized Controlled Trial of an Integrated Brain, Body, and Social Intervention for Children With ADHD.Smith SD, Vitulano LA, Katsovich L, Li S, Moore C, Li F, Grantz H, Zheng X, Eicher V, Aktan Guloksuz S, Zheng Y, Dong J, Sukhodolsky DG, Leckman JF. A Randomized Controlled Trial of an Integrated Brain, Body, and Social Intervention for Children With ADHD. Journal Of Attention Disorders 2020, 24: 780-794. PMID: 27178060, PMCID: PMC5107355, DOI: 10.1177/1087054716647490.
- Discrepancies between parent and child ratings of anxiety in children with autism spectrum disorder.Kalvin CB, Marsh CL, Ibrahim K, Gladstone TR, Woodward D, Grantz H, Ventola P, Sukhodolsky DG. Discrepancies between parent and child ratings of anxiety in children with autism spectrum disorder. Autism Research : Official Journal Of The International Society For Autism Research 2020, 13: 93-103. PMID: 31643143, PMCID: PMC7062240, DOI: 10.1002/aur.2220.
- Anxiety in 3- to 7-year-old children with autism spectrum disorder seeking treatment for disruptive behavior.Sukhodolsky DG, Lecavalier L, Johnson C, Smith T, Swiezy N, Bearss K, Kalvin CB, Scahill L. Anxiety in 3- to 7-year-old children with autism spectrum disorder seeking treatment for disruptive behavior. Autism : The International Journal Of Research And Practice 2020, 24: 400-410. PMID: 31390873, PMCID: PMC6982590, DOI: 10.1177/1362361319866561.
- Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome.Sukhodolsky DG, Walsh C, Koller WN, Eilbott J, Rance M, Fulbright RK, Zhao Z, Bloch MH, King R, Leckman JF, Scheinost D, Pittman B, Hampson M. Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome. Biological Psychiatry 2020, 87: 1063-1070. PMID: 31668476, PMCID: PMC7015800, DOI: 10.1016/j.biopsych.2019.07.035.
- Fixel-Based Diffusion Magnetic Resonance Imaging Reveals Novel Associations Between White Matter Microstructure and Childhood Aggressive Behavior.Grazioplene R, Tseng WL, Cimino K, Kalvin C, Ibrahim K, Pelphrey KA, Sukhodolsky DG. Fixel-Based Diffusion Magnetic Resonance Imaging Reveals Novel Associations Between White Matter Microstructure and Childhood Aggressive Behavior. Biological Psychiatry : Cognitive Neuroscience And Neuroimaging 2020, 5: 490-498. PMID: 32144044, PMCID: PMC7214205, DOI: 10.1016/j.bpsc.2019.12.018.
- The Role of Gender in the Associations Among Posttraumatic Stress Symptoms, Anger, and Aggression in Russian Adolescents.Isaksson J, Sukhodolsky DG, Koposov R, Stickley A, Ruchkin V. The Role of Gender in the Associations Among Posttraumatic Stress Symptoms, Anger, and Aggression in Russian Adolescents. Journal Of Traumatic Stress 2020, 33: 552-563. PMID: 32384585, DOI: 10.1002/jts.22502.
- Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index.Kalvin CB, Gladstone TR, Jordan R, Rowley S, Marsh CL, Ibrahim K, Sukhodolsky DG. Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index. Journal Of Autism And Developmental Disorders 2021, 51: 1496-1507. PMID: 32734421, PMCID: PMC7855357, DOI: 10.1007/s10803-020-04627-9.
- Reduced Amygdala-Prefrontal Functional Connectivity in Children With Autism Spectrum Disorder and Co-occurring Disruptive Behavior.Ibrahim K, Eilbott JA, Ventola P, He G, Pelphrey KA, McCarthy G, Sukhodolsky DG. Reduced Amygdala-Prefrontal Functional Connectivity in Children With Autism Spectrum Disorder and Co-occurring Disruptive Behavior. Biological Psychiatry : Cognitive Neuroscience And Neuroimaging 2019, 4: 1031-1041. PMID: 30979647, PMCID: PMC7173634, DOI: 10.1016/j.bpsc.2019.01.009.
- Anger Rumination is Associated with Restricted and Repetitive Behaviors in Children with Autism Spectrum Disorder.Ibrahim K, Kalvin C, Marsh CL, Anzano A, Gorynova L, Cimino K, Sukhodolsky DG. Anger Rumination is Associated with Restricted and Repetitive Behaviors in Children with Autism Spectrum Disorder. Journal Of Autism And Developmental Disorders 2019, 49: 3656-3668. PMID: 31144231, PMCID: PMC7035789, DOI: 10.1007/s10803-019-04085-y.
- Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD.Smith SD, Crowley MJ, Ferrey A, Ramsey K, Wexler BE, Leckman JF, Sukhodolsky DG. Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD. Psychiatry Research 2019, 278: 248-257. PMID: 31233935, PMCID: PMC6637759, DOI: 10.1016/j.psychres.2019.06.021.
- Altered Neural Connectivity in Females, But Not Males with Autism: Preliminary Evidence for the Female Protective Effect from a Quality-Controlled Diffusion Tensor Imaging Study.Lei J, Lecarie E, Jurayj J, Boland S, Sukhodolsky DG, Ventola P, Pelphrey KA, Jou RJ. Altered Neural Connectivity in Females, But Not Males with Autism: Preliminary Evidence for the Female Protective Effect from a Quality-Controlled Diffusion Tensor Imaging Study. Autism Research : Official Journal Of The International Society For Autism Research 2019, 12: 1472-1483. PMID: 31347307, PMCID: PMC6851962, DOI: 10.1002/aur.2180.
- An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder.Lewis AS, van Schalkwyk GI, Lopez MO, Volkmar FR, Picciotto MR, Sukhodolsky DG. An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder. Journal Of Autism And Developmental Disorders 2018, 48: 2748-2757. PMID: 29536216, PMCID: PMC6394231, DOI: 10.1007/s10803-018-3536-7.
- Time course of clinical change following neurofeedback.Rance M, Walsh C, Sukhodolsky DG, Pittman B, Qiu M, Kichuk SA, Wasylink S, Koller WN, Bloch M, Gruner P, Scheinost D, Pittenger C, Hampson M. Time course of clinical change following neurofeedback. NeuroImage 2018, 181: 807-813. PMID: 29729393, PMCID: PMC6454268, DOI: 10.1016/j.neuroimage.2018.05.001.
- Distinct neural bases of disruptive behavior and autism symptom severity in boys with autism spectrum disorder.Yang YJ, Sukhodolsky DG, Lei J, Dayan E, Pelphrey KA, Ventola P. Distinct neural bases of disruptive behavior and autism symptom severity in boys with autism spectrum disorder. Journal Of Neurodevelopmental Disorders 2017, 9: 1. PMID: 28115995, PMCID: PMC5240249, DOI: 10.1186/s11689-017-9183-z.
- Moderators and predictors of response to behavior therapy for tics in Tourette syndrome.Sukhodolsky DG, Woods DW, Piacentini J, Wilhelm S, Peterson AL, Katsovich L, Dziura J, Walkup JT, Scahill L. Moderators and predictors of response to behavior therapy for tics in Tourette syndrome. Neurology 2017, 88: 1029-1036. PMID: 28202705, PMCID: PMC5384839, DOI: 10.1212/WNL.0000000000003710.
- Brief report: Reduced anxiety following Pivotal Response Treatment in young children with Autism Spectrum Disorder.Lei J, Sukhodolsky DG, Abdullahi SM, Braconnier ML, Ventola P. Brief report: Reduced anxiety following Pivotal Response Treatment in young children with Autism Spectrum Disorder. Research In Autism Spectrum Disorders 2017, 43-44: 1-7. PMID: 29333196, PMCID: PMC5761743, DOI: 10.1016/j.rasd.2017.09.002.
- Meta-analysis of organizational skills interventions for children and adolescents with Attention-Deficit/Hyperactivity Disorder.Bikic A, Reichow B, McCauley SA, Ibrahim K, Sukhodolsky DG. Meta-analysis of organizational skills interventions for children and adolescents with Attention-Deficit/Hyperactivity Disorder. Clinical Psychology Review 2017, 52: 108-123. PMID: 28088557, DOI: 10.1016/j.cpr.2016.12.004.
- Extended-Release Guanfacine Does Not Show a Large Effect on Tic Severity in Children with Chronic Tic Disorders.Murphy TK, Fernandez TV, Coffey BJ, Rahman O, Gavaletz A, Hanks CE, Tillberg CS, Gomez LI, Sukhodolsky DG, Katsovich L, Scahill L. Extended-Release Guanfacine Does Not Show a Large Effect on Tic Severity in Children with Chronic Tic Disorders. Journal Of Child And Adolescent Psychopharmacology 2017, 27: 762-770. PMID: 28723227, DOI: 10.1089/cap.2017.0024.
- Moderators of Parent Training for Disruptive Behaviors in Young Children with Autism Spectrum Disorder.Lecavalier L, Smith T, Johnson C, Bearss K, Swiezy N, Aman MG, Sukhodolsky DG, Deng Y, Dziura J, Scahill L. Moderators of Parent Training for Disruptive Behaviors in Young Children with Autism Spectrum Disorder. Journal Of Abnormal Child Psychology 2017, 45: 1235-1245. PMID: 27917460, PMCID: PMC5459681, DOI: 10.1007/s10802-016-0233-x.
- Effect of Parent Training on Adaptive Behavior in Children With Autism Spectrum Disorder and Disruptive Behavior: Results of a Randomized Trial.Scahill L, Bearss K, Lecavalier L, Smith T, Swiezy N, Aman MG, Sukhodolsky DG, McCracken C, Minshawi N, Turner K, Levato L, Saulnier C, Dziura J, Johnson C. Effect of Parent Training on Adaptive Behavior in Children With Autism Spectrum Disorder and Disruptive Behavior: Results of a Randomized Trial. Journal Of The American Academy Of Child And Adolescent Psychiatry 2016, 55: 602-609.e3. PMID: 27343887, DOI: 10.1016/j.jaac.2016.05.001.
- Brief Report: Reduced Restricted and Repetitive Behaviors after Pivotal Response Treatment.Ventola PE, Yang D, Abdullahi SM, Paisley CA, Braconnier ML, Sukhodolsky DG. Brief Report: Reduced Restricted and Repetitive Behaviors after Pivotal Response Treatment. Journal Of Autism And Developmental Disorders 2016, 46: 2813-2820. PMID: 27230762, PMCID: PMC4939123, DOI: 10.1007/s10803-016-2813-6.
- Psychometric Properties of the Spanish Adaptation of the Anger Rumination Scale: Evidence of Reliability and Validity in the General Population.Magán Uceda I, Lozano Bleda JH, Pérez Nieto MÁ, Sukhodolsky DG, Escalona Martínez A. Psychometric Properties of the Spanish Adaptation of the Anger Rumination Scale: Evidence of Reliability and Validity in the General Population. The Spanish Journal Of Psychology 2016, 19: E17. PMID: 27103336, DOI: 10.1017/sjp.2016.17.
- A Randomized Controlled Study of Cognitive-Behavioral Therapy for Posttraumatic Stress in Street Children in Mexico City.Shein-Szydlo J, Sukhodolsky DG, Kon DS, Tejeda MM, Ramirez E, Ruchkin V. A Randomized Controlled Study of Cognitive-Behavioral Therapy for Posttraumatic Stress in Street Children in Mexico City. Journal Of Traumatic Stress 2016, 29: 406-414. PMID: 27602880, DOI: 10.1002/jts.22124.
- Neural Mechanisms of Cognitive-Behavioral Therapy for Aggression in Children and Adolescents: Design of a Randomized Controlled Trial Within the National Institute for Mental Health Research Domain Criteria Construct of Frustrative Non-Reward.Sukhodolsky DG, Vander Wyk BC, Eilbott JA, McCauley SA, Ibrahim K, Crowley MJ, Pelphrey KA. Neural Mechanisms of Cognitive-Behavioral Therapy for Aggression in Children and Adolescents: Design of a Randomized Controlled Trial Within the National Institute for Mental Health Research Domain Criteria Construct of Frustrative Non-Reward. Journal Of Child And Adolescent Psychopharmacology 2016, 26: 38-48. PMID: 26784537, PMCID: PMC4779273, DOI: 10.1089/cap.2015.0164.
- Sensitivity of the modified Children's Yale-Brown Obsessive Compulsive Scale to detect change: Results from two multi-site trials.Scahill L, Sukhodolsky DG, Anderberg E, Dimitropoulos A, Dziura J, Aman MG, McCracken J, Tierney E, Hallett V, Katz K, Vitiello B, McDougle C. Sensitivity of the modified Children's Yale-Brown Obsessive Compulsive Scale to detect change: Results from two multi-site trials. Autism : The International Journal Of Research And Practice 2016, 20: 145-52. PMID: 25882391, DOI: 10.1177/1362361315574889.
- Behavioral Interventions for Anger, Irritability, and Aggression in Children and Adolescents.Sukhodolsky DG, Smith SD, McCauley SA, Ibrahim K, Piasecka JB. Behavioral Interventions for Anger, Irritability, and Aggression in Children and Adolescents. Journal Of Child And Adolescent Psychopharmacology 2016, 26: 58-64. PMID: 26745682, PMCID: PMC4808268, DOI: 10.1089/cap.2015.0120.
- Cognitive-Behavioral Therapy for a 9-Year-Old Girl With Disruptive Mood Dysregulation Disorder.Tudor ME, Ibrahim K, Bertschinger E, Piasecka J, Sukhodolsky DG. Cognitive-Behavioral Therapy for a 9-Year-Old Girl With Disruptive Mood Dysregulation Disorder. Clinical Case Studies 2016, 15: 459-475. PMID: 29081722, PMCID: PMC5658126, DOI: 10.1177/1534650116669431.
- Clinical Correlates and Predictors of Caregiver Strain in Children with Chronic Tic Disorders.Ramanujam K, Himle MB, Hayes LP, Woods DW, Scahill L, Sukhodolsky DG, Wilhelm S, Deckersbach T, Peterson AL, Specht M, Walkup JT, Chang S, Piacentini J. Clinical Correlates and Predictors of Caregiver Strain in Children with Chronic Tic Disorders. Children's Health Care : Journal Of The Association For The Care Of Children's Health 2015, 44: 249-263. PMID: 26855465, PMCID: PMC4739807, DOI: 10.1080/02739615.2014.948166.
- Heterogeneity of neural mechanisms of response to pivotal response treatment.Ventola P, Yang DY, Friedman HE, Oosting D, Wolf J, Sukhodolsky DG, Pelphrey KA. Heterogeneity of neural mechanisms of response to pivotal response treatment. Brain Imaging And Behavior 2015, 9: 74-88. PMID: 25370452, PMCID: PMC4993028, DOI: 10.1007/s11682-014-9331-y.
- Effect of parent training vs parent education on behavioral problems in children with autism spectrum disorder: a randomized clinical trial.Bearss K, Johnson C, Smith T, Lecavalier L, Swiezy N, Aman M, McAdam DB, Butter E, Stillitano C, Minshawi N, Sukhodolsky DG, Mruzek DW, Turner K, Neal T, Hallett V, Mulick JA, Green B, Handen B, Deng Y, Dziura J, Scahill L. Effect of parent training vs parent education on behavioral problems in children with autism spectrum disorder: a randomized clinical trial. JAMA 2015, 313: 1524-33. PMID: 25898050, PMCID: PMC9078140, DOI: 10.1001/jama.2015.3150.
- Variables Associated With Tic Exacerbation in Children With Chronic Tic Disorders.Himle MB, Capriotti MR, Hayes LP, Ramanujam K, Scahill L, Sukhodolsky DG, Wilhelm S, Deckersbach T, Peterson AL, Specht MW, Walkup JT, Chang S, Piacentini J. Variables Associated With Tic Exacerbation in Children With Chronic Tic Disorders. Behavior Modification 2014, 38: 163-83. PMID: 24778433, PMCID: PMC4211980, DOI: 10.1177/0145445514531016.
- Examination of aggression and self-injury in children with autism spectrum disorders and serious behavioral problems.Carroll D, Hallett V, McDougle CJ, Aman MG, McCracken JT, Tierney E, Arnold LE, Sukhodolsky DG, Lecavalier L, Handen BL, Swiezy N, Johnson C, Bearss K, Vitiello B, Scahill L. Examination of aggression and self-injury in children with autism spectrum disorders and serious behavioral problems. Child And Adolescent Psychiatric Clinics Of North America 2014, 23: 57-72. PMID: 24231167, PMCID: PMC4212264, DOI: 10.1016/j.chc.2013.08.002.
- Individualized assessments in treatment research: an examination of parent-nominated target problems in the treatment of disruptive behaviors in youth with Tourette syndrome.McGuire JF, Sukhodolsky DG, Bearss K, Grantz H, Pachler M, Lombroso PJ, Scahill L. Individualized assessments in treatment research: an examination of parent-nominated target problems in the treatment of disruptive behaviors in youth with Tourette syndrome. Child Psychiatry And Human Development 2014, 45: 686-94. PMID: 24477478, DOI: 10.1007/s10578-014-0437-7.
- Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders.Handen BL, Johnson CR, Butter EM, Lecavalier L, Scahill L, Aman MG, McDougle CJ, Arnold LE, Swiezy NB, Sukhodolsky DG, Mulick JA, White SW, Bearss K, Hollway JA, Stigler KA, Dziura J, Yu S, Sacco K, Vitiello B. Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders. Journal Of Developmental And Physical Disabilities 2013, 25: 355-371. PMID: 23730123, PMCID: PMC3665525, DOI: 10.1007/s10882-012-9316-y.
- Toward an exportable parent training program for disruptive behaviors in autism spectrum disorders.Bearss K, Lecavalier L, Minshawi N, Johnson C, Smith T, Handen B, Sukhodolsky D, Aman M, Swiezy N, Butter E, Scahill L. Toward an exportable parent training program for disruptive behaviors in autism spectrum disorders. Neuropsychiatry 2013, 3: 169-180. PMID: 23772233, PMCID: PMC3678377, DOI: 10.2217/npy.13.14.
- Cognitive-behavioral therapy for anxiety in children with high-functioning autism: a meta-analysis.Sukhodolsky DG, Bloch MH, Panza KE, Reichow B. Cognitive-behavioral therapy for anxiety in children with high-functioning autism: a meta-analysis. Pediatrics 2013, 132: e1341-50. PMID: 24167175, PMCID: PMC3813396, DOI: 10.1542/peds.2013-1193.
- Exploring the manifestations of anxiety in children with autism spectrum disorders.Hallett V, Lecavalier L, Sukhodolsky DG, Cipriano N, Aman MG, McCracken JT, McDougle CJ, Tierney E, King BH, Hollander E, Sikich L, Bregman J, Anagnostou E, Donnelly C, Katsovich L, Dukes K, Vitiello B, Gadow K, Scahill L. Exploring the manifestations of anxiety in children with autism spectrum disorders. Journal Of Autism And Developmental Disorders 2013, 43: 2341-52. PMID: 23400347, PMCID: PMC4038127, DOI: 10.1007/s10803-013-1775-1.
- Exposure and response prevention with or without parent management training for children with obsessive-compulsive disorder complicated by disruptive behavior: a multiple-baseline across-responses design study.Sukhodolsky DG, Gorman BS, Scahill L, Findley D, McGuire J. Exposure and response prevention with or without parent management training for children with obsessive-compulsive disorder complicated by disruptive behavior: a multiple-baseline across-responses design study. Journal Of Anxiety Disorders 2013, 27: 298-305. PMID: 23602943, DOI: 10.1016/j.janxdis.2013.01.005.
- Randomized trial of behavior therapy for adults with Tourette syndrome.Wilhelm S, Peterson AL, Piacentini J, Woods DW, Deckersbach T, Sukhodolsky DG, Chang S, Liu H, Dziura J, Walkup JT, Scahill L. Randomized trial of behavior therapy for adults with Tourette syndrome. Archives Of General Psychiatry 2012, 69: 795-803. PMID: 22868933, PMCID: PMC3772729, DOI: 10.1001/archgenpsychiatry.2011.1528.
- Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems.Scahill L, McDougle CJ, Aman MG, Johnson C, Handen B, Bearss K, Dziura J, Butter E, Swiezy NG, Arnold LE, Stigler KA, Sukhodolsky DD, Lecavalier L, Pozdol SL, Nikolov R, Hollway JA, Korzekwa P, Gavaletz A, Kohn AE, Koenig K, Grinnon S, Mulick JA, Yu S, Vitiello B. Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems. Journal Of The American Academy Of Child And Adolescent Psychiatry 2012, 51: 136-46. PMID: 22265360, PMCID: PMC3941712, DOI: 10.1016/j.jaac.2011.11.010.
- Poor fine-motor and visuospatial skills predict persistence of pediatric-onset obsessive-compulsive disorder into adulthood.Bloch MH, Sukhodolsky DG, Dombrowski PA, Panza KE, Craiglow BG, Landeros-Weisenberger A, Leckman JF, Peterson BS, Schultz RT. Poor fine-motor and visuospatial skills predict persistence of pediatric-onset obsessive-compulsive disorder into adulthood. Journal Of Child Psychology And Psychiatry, And Allied Disciplines 2011, 52: 974-83. PMID: 21244423, PMCID: PMC3625937, DOI: 10.1111/j.1469-7610.2010.02366.x.
- Adverse effects of heavy prenatal maternal smoking on attentional control in children with ADHD.Motlagh MG, Sukhodolsky DG, Landeros-Weisenberger A, Katsovich L, Thompson N, Scahill L, King RA, Peterson BS, Schultz RT, Leckman JF. Adverse effects of heavy prenatal maternal smoking on attentional control in children with ADHD. Journal Of Attention Disorders 2011, 15: 593-603. PMID: 20616372, PMCID: PMC3974616, DOI: 10.1177/1087054710374576.
- The Home Situations Questionnaire-PDD version: factor structure and psychometric properties.Chowdhury M, Aman MG, Scahill L, Swiezy N, Arnold LE, Lecavalier L, Johnson C, Handen B, Stigler K, Bearss K, Sukhodolsky D, McDougle CJ. The Home Situations Questionnaire-PDD version: factor structure and psychometric properties. Journal Of Intellectual Disability Research : JIDR 2010, 54: 281-91. PMID: 20377705, DOI: 10.1111/j.1365-2788.2010.01259.x.
- Neuropsychological functioning in children with Tourette syndrome with and without attention-deficit/hyperactivity disorder.Sukhodolsky DG, Landeros-Weisenberger A, Scahill L, Leckman JF, Schultz RT. Neuropsychological functioning in children with Tourette syndrome with and without attention-deficit/hyperactivity disorder. Journal Of The American Academy Of Child And Adolescent Psychiatry 2010, 49: 1155-64. PMID: 20970703, PMCID: PMC2965169, DOI: 10.1016/j.jaac.2010.08.008.
- Standardised Observation Analogue Procedure (SOAP) for assessing parent and child behaviours in clinical trials.Johnson CR, Butter EM, Handen BL, Sukhodolsky DG, Mulick J, Lecavalier L, Aman MG, Arnold LE, Scahill L, Swiezy N, Sacco K, Stigler KA, McDougle CJ. Standardised Observation Analogue Procedure (SOAP) for assessing parent and child behaviours in clinical trials. Journal Of Intellectual & Developmental Disability 2009, 34: 230-8. PMID: 19681003, PMCID: PMC2739602, DOI: 10.1080/13668250903074471.
- Medication and parent training in children with pervasive developmental disorders and serious behavior problems: results from a randomized clinical trial.Aman MG, McDougle CJ, Scahill L, Handen B, Arnold LE, Johnson C, Stigler KA, Bearss K, Butter E, Swiezy NB, Sukhodolsky DD, Ramadan Y, Pozdol SL, Nikolov R, Lecavalier L, Kohn AE, Koenig K, Hollway JA, Korzekwa P, Gavaletz A, Mulick JA, Hall KL, Dziura J, Ritz L, Trollinger S, Yu S, Vitiello B, Wagner A. Medication and parent training in children with pervasive developmental disorders and serious behavior problems: results from a randomized clinical trial. Journal Of The American Academy Of Child And Adolescent Psychiatry 2009, 48: 1143-54. PMID: 19858761, PMCID: PMC3142923, DOI: 10.1097/CHI.0b013e3181bfd669.
- Trial design challenges when combining medication and parent training in children with pervasive developmental disorders.Scahill L, Aman MG, McDougle CJ, Arnold LE, McCracken JT, Handen B, Johnson C, Dziura J, Butter E, Sukhodolsky D, Swiezy N, Mulick J, Stigler K, Bearss K, Ritz L, Wagner A, Vitiello B. Trial design challenges when combining medication and parent training in children with pervasive developmental disorders. Journal Of Autism And Developmental Disorders 2009, 39: 720-9. PMID: 19096921, PMCID: PMC4807607, DOI: 10.1007/s10803-008-0675-2.
- Randomized trial of anger control training for adolescents with Tourette's syndrome and disruptive behavior.Sukhodolsky DG, Vitulano LA, Carroll DH, McGuire J, Leckman JF, Scahill L. Randomized trial of anger control training for adolescents with Tourette's syndrome and disruptive behavior. Journal Of The American Academy Of Child And Adolescent Psychiatry 2009, 48: 413-421. PMID: 19242384, DOI: 10.1097/CHI.0b013e3181985050.
- ADHD symptoms and associated psychopathology in a community sample of adolescents from the European north of Russia.Ruchkin V, Lorberg B, Koposov R, Schwab-Stone M, Sukhodolsky DG. ADHD symptoms and associated psychopathology in a community sample of adolescents from the European north of Russia. Journal Of Attention Disorders 2008, 12: 54-63. PMID: 17712166, DOI: 10.1177/1087054707305169.
- Four-factor structure of obsessive-compulsive disorder symptoms in children, adolescents, and adults.Stewart SE, Rosario MC, Baer L, Carter AS, Brown TA, Scharf JM, Illmann C, Leckman JF, Sukhodolsky D, Katsovich L, Rasmussen S, Goodman W, Delorme R, Leboyer M, Chabane N, Jenike MA, Geller DA, Pauls DL. Four-factor structure of obsessive-compulsive disorder symptoms in children, adolescents, and adults. Journal Of The American Academy Of Child And Adolescent Psychiatry 2008, 47: 763-772. PMID: 18520961, DOI: 10.1097/CHI.0b013e318172ef1e.
- Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.Sukhodolsky DG, Scahill L, Gadow KD, Arnold LE, Aman MG, McDougle CJ, McCracken JT, Tierney E, Williams White S, Lecavalier L, Vitiello B. Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning. Journal Of Abnormal Child Psychology 2008, 36: 117-28. PMID: 17674186, DOI: 10.1007/s10802-007-9165-9.
- Principal components analysis of obsessive-compulsive disorder symptoms in children and adolescents.Stewart SE, Rosario MC, Brown TA, Carter AS, Leckman JF, Sukhodolsky D, Katsovitch L, King R, Geller D, Pauls DL. Principal components analysis of obsessive-compulsive disorder symptoms in children and adolescents. Biological Psychiatry 2007, 61: 285-91. PMID: 17161383, DOI: 10.1016/j.biopsych.2006.08.040.
- The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder.Sukhodolsky DG, Leckman JF, Rothenberger A, Scahill L. The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder. European Child & Adolescent Psychiatry 2007, 16 Suppl 1: 51-9. PMID: 17665283, DOI: 10.1007/s00787-007-1007-3.
- Drug and non-drug treatments of children with ADHD and tic disorders.Poncin Y, Sukhodolsky DG, McGuire J, Scahill L. Drug and non-drug treatments of children with ADHD and tic disorders. European Child & Adolescent Psychiatry 2007, 16 Suppl 1: 78-88. PMID: 17665286, DOI: 10.1007/s00787-007-1010-8.
- Review: evidence-based treatments are more effective than usual care for youths with psychological problems and maladaptive behaviour.Sukhodolsky DG. Review: evidence-based treatments are more effective than usual care for youths with psychological problems and maladaptive behaviour. Evidence-based Mental Health 2007, 10: 53. PMID: 17459984, DOI: 10.1136/ebmh.10.2.53.
- Fine-motor skill deficits in childhood predict adulthood tic severity and global psychosocial functioning in Tourette's syndrome.Bloch MH, Sukhodolsky DG, Leckman JF, Schultz RT. Fine-motor skill deficits in childhood predict adulthood tic severity and global psychosocial functioning in Tourette's syndrome. Journal Of Child Psychology And Psychiatry, And Allied Disciplines 2006, 47: 551-9. PMID: 16712631, DOI: 10.1111/j.1469-7610.2005.01561.x.
- Randomized trial of parent management training in children with tic disorders and disruptive behavior.Scahill L, Sukhodolsky DG, Bearss K, Findley D, Hamrin V, Carroll DH, Rains AL. Randomized trial of parent management training in children with tic disorders and disruptive behavior. Journal Of Child Neurology 2006, 21: 650-6. PMID: 16970865, DOI: 10.1177/08830738060210080201.
- Evidence-based psychosocial treatments in the juvenile justice system.Sukhodolsky DG, Ruchkin V. Evidence-based psychosocial treatments in the juvenile justice system. Child And Adolescent Psychiatric Clinics Of North America 2006, 15: 501-16, x. PMID: 16527668, DOI: 10.1016/j.chc.2005.11.005.
- Depressive symptoms and associated psychopathology in urban adolescents: a cross-cultural study of three countries.Ruchkin V, Sukhodolsky DG, Vermeiren R, Koposov RA, Schwab-Stone M. Depressive symptoms and associated psychopathology in urban adolescents: a cross-cultural study of three countries. The Journal Of Nervous And Mental Disease 2006, 194: 106-13. PMID: 16477188, DOI: 10.1097/01.nmd.0000198142.26754.18.
- Adaptive, emotional, and family functioning of children with obsessive-compulsive disorder and comorbid attention deficit hyperactivity disorder.Sukhodolsky DG, do Rosario-Campos MC, Scahill L, Katsovich L, Pauls DL, Peterson BS, King RA, Lombroso PJ, Findley DB, Leckman JF. Adaptive, emotional, and family functioning of children with obsessive-compulsive disorder and comorbid attention deficit hyperactivity disorder. The American Journal Of Psychiatry 2005, 162: 1125-32. PMID: 15930061, PMCID: PMC2291297, DOI: 10.1176/appi.ajp.162.6.1125.
- Characterizing aggressive and noncompliant behaviors in a children's psychiatric inpatient setting.Sukhodolsky DG, Cardona L, Martin A. Characterizing aggressive and noncompliant behaviors in a children's psychiatric inpatient setting. Child Psychiatry And Human Development 2005, 36: 177-93. PMID: 16228146, DOI: 10.1007/s10578-005-3494-0.
- Public health significance of tic disorders in children and adolescents.Scahill L, Sukhodolsky DG, Williams SK, Leckman JF. Public health significance of tic disorders in children and adolescents. Advances In Neurology 2005, 96: 240-8. PMID: 16383223.
- The impact of managed care on children's outpatient treatment: a comparison study of treatment outcome before and after managed care.Armbruster P, Sukhodolsky D, Michalsen R. The impact of managed care on children's outpatient treatment: a comparison study of treatment outcome before and after managed care. The American Journal Of Orthopsychiatry 2004, 74: 5-13. PMID: 14769104, DOI: 10.1037/0002-9432.74.1.5.
- Association of normative beliefs and anger with aggression and antisocial behavior in Russian male juvenile offenders and high school students.Sukhodolsky DG, Ruchkin VV. Association of normative beliefs and anger with aggression and antisocial behavior in Russian male juvenile offenders and high school students. Journal Of Abnormal Child Psychology 2004, 32: 225-36. PMID: 15164863, DOI: 10.1023/b:jacp.0000019773.86910.fe.
- Disruptive behavior in children with Tourette's syndrome: association with ADHD comorbidity, tic severity, and functional impairment.Sukhodolsky DG, Scahill L, Zhang H, Peterson BS, King RA, Lombroso PJ, Katsovich L, Findley D, Leckman JF. Disruptive behavior in children with Tourette's syndrome: association with ADHD comorbidity, tic severity, and functional impairment. Journal Of The American Academy Of Child And Adolescent Psychiatry 2003, 42: 98-105. PMID: 12500082, DOI: 10.1097/00004583-200301000-00016.
- Developmental Course and Risk Factors of Physical Aggression in Late Adolescence.Henriksen M, Skrove M, Hoftun GB, Sund ER, Lydersen S, Tseng WL, Sukhodolsky DG. Developmental Course and Risk Factors of Physical Aggression in Late Adolescence. Child Psychiatry And Human Development 2021, 52: 628-639. PMID: 32852728, PMCID: PMC8238740, DOI: 10.1007/s10578-020-01049-7.
- Tantrum Tool: Development and Open Pilot Study of Online Parent Training for Irritability and Disruptive Behavior.Diaz-Stransky A, Rowley S, Zecher E, Grodberg D, Sukhodolsky DG. Tantrum Tool: Development and Open Pilot Study of Online Parent Training for Irritability and Disruptive Behavior. Journal Of Child And Adolescent Psychopharmacology 2020, 30: 558-566. PMID: 33035067, PMCID: PMC7699014, DOI: 10.1089/cap.2020.0089.
- Sex differences in medial prefrontal and parietal cortex structure in children with disruptive behavior.Ibrahim K, Kalvin C, Li F, He G, Pelphrey KA, McCarthy G, Sukhodolsky DG. Sex differences in medial prefrontal and parietal cortex structure in children with disruptive behavior. Developmental Cognitive Neuroscience 2021, 47: 100884. PMID: 33254067, PMCID: PMC7704291, DOI: 10.1016/j.dcn.2020.100884.
- Conducting CBT for Anxiety in Children with Autism Spectrum Disorder During COVID-19 Pandemic.Kalvin CB, Jordan RP, Rowley SN, Weis A, Wood KS, Wood JJ, Ibrahim K, Sukhodolsky DG. Conducting CBT for Anxiety in Children with Autism Spectrum Disorder During COVID-19 Pandemic. Journal Of Autism And Developmental Disorders 2021, 51: 4239-4247. PMID: 33385281, PMCID: PMC7775616, DOI: 10.1007/s10803-020-04845-1.
- Parent Emotion Socialization in Children with Autism Spectrum Disorder and Co-Occurring Anxiety.Jordan R, Kalvin CB, Ibrahim K, Sukhodolsky DG. Parent Emotion Socialization in Children with Autism Spectrum Disorder and Co-Occurring Anxiety. Research On Child And Adolescent Psychopathology 2021, 49: 125-137. PMID: 33442839, PMCID: PMC7809195, DOI: 10.1007/s10802-020-00731-7.
- Increased Alpha-Band Connectivity During Tic Suppression in Children With Tourette Syndrome Revealed by Source Electroencephalography Analyses.Morand-Beaulieu S, Wu J, Mayes LC, Grantz H, Leckman JF, Crowley MJ, Sukhodolsky DG. Increased Alpha-Band Connectivity During Tic Suppression in Children With Tourette Syndrome Revealed by Source Electroencephalography Analyses. Biological Psychiatry : Cognitive Neuroscience And Neuroimaging 2021 PMID: 33991741, PMCID: PMC8589865, DOI: 10.1016/j.bpsc.2021.05.001.
- Large-scale functional brain networks of maladaptive childhood aggression identified by connectome-based predictive modeling.Ibrahim K, Noble S, He G, Lacadie C, Crowley MJ, McCarthy G, Scheinost D, Sukhodolsky DG. Large-scale functional brain networks of maladaptive childhood aggression identified by connectome-based predictive modeling. Molecular Psychiatry 2022, 27: 985-999. PMID: 34690348, PMCID: PMC9035467, DOI: 10.1038/s41380-021-01317-5.
- Organizational skills training for children with ADHD: study protocol for a randomized, controlled trial.Bikic A, Dalsgaard S, Olsen KD, Sukhodolsky DG. Organizational skills training for children with ADHD: study protocol for a randomized, controlled trial. Trials 2021, 22: 752. PMID: 34715906, PMCID: PMC8556963, DOI: 10.1186/s13063-021-05499-9.
- What are we optimizing for in autism screening? Examination of algorithmic changes in the M-CHAT.Schjølberg S, Shic F, Volkmar FR, Nordahl-Hansen A, Stenberg N, Torske T, Larsen K, Riley K, Sukhodolsky DG, Leckman JF, Chawarska K, Øien RA. What are we optimizing for in autism screening? Examination of algorithmic changes in the M-CHAT. Autism Research : Official Journal Of The International Society For Autism Research 2022, 15: 296-304. PMID: 34837355, PMCID: PMC8821132, DOI: 10.1002/aur.2643.
- Increased Amygdala and Decreased Frontolimbic Resting State Functional Connectivity in Children with Aggressive Behavior.Sukhodolsky DG, Ibrahim K, Kalvin CB, Jordan RP, Eilbott J, Hampson M. Increased Amygdala and Decreased Frontolimbic Resting State Functional Connectivity in Children with Aggressive Behavior. Social Cognitive And Affective Neuroscience 2021 PMID: 34850939, DOI: 10.1093/scan/nsab128.
- Electrophysiological signatures of inhibitory control in children with Tourette syndrome and attention-deficit/hyperactivity disorder.Morand-Beaulieu S, Smith SD, Ibrahim K, Wu J, Leckman JF, Crowley MJ, Sukhodolsky DG. Electrophysiological signatures of inhibitory control in children with Tourette syndrome and attention-deficit/hyperactivity disorder. Cortex; A Journal Devoted To The Study Of The Nervous System And Behavior 2022, 147: 157-168. PMID: 35042055, PMCID: PMC8816877, DOI: 10.1016/j.cortex.2021.12.006.
- Posttraumatic Stress and Perceived Interpersonal Provocation in Adolescents.Saunderson JM, Stickley A, Sturidsson K, Koposov R, Sukhodolsky DG, Ruchkin V. Posttraumatic Stress and Perceived Interpersonal Provocation in Adolescents. Journal Of Interpersonal Violence 2022, 8862605221104525. PMID: 35613735, DOI: 10.1177/08862605221104525.
Clinical Trials
Conditions | Study Title |
---|---|
Child Development & Autism; Children's Health; Mental Health & Behavioral Research | Anger Control Training for Youth With Tourette Syndrome |
Children's Health; Men's Health; Mental Health & Behavioral Research; Women's Health | ACE Multisite Study of Adolescent & Adult Transitions |
Children's Health | A Short-Term Longitudinal Study of the Brain Mechanisms of Childhood Irritability |
Child Development & Autism; Children's Health; Mental Health & Behavioral Research | CBT for Anxiety in Children With Autism |
Diseases of the Nervous System; Mental Health & Behavioral Research | Neurofeedback for Obsessive-Compulsive Disorder |
Child Development & Autism; Genetics - Adult; Genetics - Pediatric; Mental Health & Behavioral Research | Pivotal Response Treatment for Children With Autism Spectrum Disorders (PRT) |