Daniel Coman, PhD

• Alvaro Duque
• Angelique Bordey
• Anita Huttner
• Basavaraju Sanganahalli
• D. S. Fahmeed Hyder
• David C. Madoff
• David Stitelman
• Douglas Rothman
• Hal Blumenfeld
• Jane Taylor
• Jiangbing Zhou
• Joseph Piepmeier
• Julius Chapiro
• Ke Dong
• Kevin Behar
• Kevin Sheth
• Lawrence Staib
• Lihong Jiang
• Longbo Zhang
• Mollie Freedman-Weiss
• Peter Herman
• Robert Shulman
• Robin de Graaf
• Samuel Maritim
• Sandeep Kumar (Mishra)
• Sarah Ullrich
• Stefan Somlo
• Stephen Strittmatter
• Tamas Horvath
• Tarek Fahmy
• Todd Schlachter
• Vittorio Gallo
• W. Mark Saltzman
• William Cafferty
• Xenophon Papademetris
• Xin Tian
• Xingxing Wang

Brain Neoplasms; Liver Neoplasms; Molecular Imaging

• Distribution of temperature changes and neurovascular coupling in rat brain following 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") exposure.Coman D, Sanganahalli BG, Jiang L, Hyder F, Behar KL. Distribution of temperature changes and neurovascular coupling in rat brain following 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") exposure. NMR In Biomedicine 2015, 28: 1257-66. PMID: 26286889, PMCID: PMC4573923, DOI: 10.1002/nbm.3375.
• Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance.Strohbehn G, Coman D, Han L, Ragheb RR, Fahmy TM, Huttner AJ, Hyder F, Piepmeier JM, Saltzman WM, Zhou J. Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance. Journal Of Neuro-oncology 2015, 121: 441-9. PMID: 25403507, PMCID: PMC4323763, DOI: 10.1007/s11060-014-1658-0.
• Lanthanide ion (III) complexes of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraaminophosphonate for dual biosensing of pH with chemical exchange saturation transfer (CEST) and biosensor imaging of redundant deviation in shifts (BIRDS).Huang Y, Coman D, Ali MM, Hyder F. Lanthanide ion (III) complexes of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraaminophosphonate for dual biosensing of pH with chemical exchange saturation transfer (CEST) and biosensor imaging of redundant deviation in shifts (BIRDS). Contrast Media & Molecular Imaging 2015, 10: 51-8. PMID: 24801742, PMCID: PMC4222994, DOI: 10.1002/cmmi.1604.
• Intranasal epidermal growth factor treatment rescues neonatal brain injury.Scafidi J, Hammond TR, Scafidi S, Ritter J, Jablonska B, Roncal M, Szigeti-Buck K, Coman D, Huang Y, McCarter RJ, Hyder F, Horvath TL, Gallo V. Intranasal epidermal growth factor treatment rescues neonatal brain injury. Nature 2014, 506: 230-4. PMID: 24390343, PMCID: PMC4106485, DOI: 10.1038/nature12880.
• Characterization of a lanthanide complex encapsulated with MRI contrast agents into liposomes for biosensor imaging of redundant deviation in shifts (BIRDS).Maritim S, Huang Y, Coman D, Hyder F. Characterization of a lanthanide complex encapsulated with MRI contrast agents into liposomes for biosensor imaging of redundant deviation in shifts (BIRDS). Journal Of Biological Inorganic Chemistry : JBIC : A Publication Of The Society Of Biological Inorganic Chemistry 2014, 19: 1385-98. PMID: 25304046, PMCID: PMC4348029, DOI: 10.1007/s00775-014-1200-z.
• Caloric restriction impedes age-related decline of mitochondrial function and neuronal activity.Lin AL, Coman D, Jiang L, Rothman DL, Hyder F. Caloric restriction impedes age-related decline of mitochondrial function and neuronal activity. Journal Of Cerebral Blood Flow And Metabolism : Official Journal Of The International Society Of Cerebral Blood Flow And Metabolism 2014, 34: 1440-3. PMID: 24984898, PMCID: PMC4158670, DOI: 10.1038/jcbfm.2014.114.
• Diffusion tensor imaging as a predictor of locomotor function after experimental spinal cord injury and recovery.Kelley BJ, Harel NY, Kim CY, Papademetris X, Coman D, Wang X, Hasan O, Kaufman A, Globinsky R, Staib LH, Cafferty WB, Hyder F, Strittmatter SM. Diffusion tensor imaging as a predictor of locomotor function after experimental spinal cord injury and recovery. Journal Of Neurotrauma 2014, 31: 1362-73. PMID: 24779685, PMCID: PMC4120934, DOI: 10.1089/neu.2013.3238.
• Mapping phosphorylation rate of fluoro-deoxy-glucose in rat brain by (19)F chemical shift imaging.Coman D, Sanganahalli BG, Cheng D, McCarthy T, Rothman DL, Hyder F. Mapping phosphorylation rate of fluoro-deoxy-glucose in rat brain by (19)F chemical shift imaging. Magnetic Resonance Imaging 2014, 32: 305-13. PMID: 24581725, PMCID: PMC3965601, DOI: 10.1016/j.mri.2013.10.015.
• Anti-epileptogenesis: Electrophysiology, diffusion tensor imaging and behavior in a genetic absence model.van Luijtelaar G, Mishra AM, Edelbroek P, Coman D, Frankenmolen N, Schaapsmeerders P, Covolato G, Danielson N, Niermann H, Janeczko K, Kiemeneij A, Burinov J, Bashyal C, Coquillette M, Lüttjohann A, Hyder F, Blumenfeld H, van Rijn CM. Anti-epileptogenesis: Electrophysiology, diffusion tensor imaging and behavior in a genetic absence model. Neurobiology Of Disease 2013, 60: 126-38. PMID: 23978468, PMCID: PMC3952020, DOI: 10.1016/j.nbd.2013.08.013.
• In vivo three-dimensional molecular imaging with Biosensor Imaging of Redundant Deviation in Shifts (BIRDS) at high spatiotemporal resolution.Coman D, de Graaf RA, Rothman DL, Hyder F. In vivo three-dimensional molecular imaging with Biosensor Imaging of Redundant Deviation in Shifts (BIRDS) at high spatiotemporal resolution. NMR In Biomedicine 2013, 26: 1589-95. PMID: 23881869, PMCID: PMC3800475, DOI: 10.1002/nbm.2995.
• Neuroanatomical changes in a mouse model of early life neglect.Duque A, Coman D, Carlyle BC, Bordner KA, George ED, Papademetris X, Hyder F, Simen AA. Neuroanatomical changes in a mouse model of early life neglect. Brain Structure & Function 2012, 217: 459-72. PMID: 21984312, PMCID: PMC3664301, DOI: 10.1007/s00429-011-0350-9.
• Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits.Carlyle BC, Duque A, Kitchen RR, Bordner KA, Coman D, Doolittle E, Papademetris X, Hyder F, Taylor JR, Simen AA. Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits. Development And Psychopathology 2012, 24: 1401-16. PMID: 23062306, PMCID: PMC3681803, DOI: 10.1017/S095457941200079X.
• Role of ongoing, intrinsic activity of neuronal populations for quantitative neuroimaging of functional magnetic resonance imaging-based networks.Hyder F, Herman P, Sanganahalli BG, Coman D, Blumenfeld H, Rothman DL. Role of ongoing, intrinsic activity of neuronal populations for quantitative neuroimaging of functional magnetic resonance imaging-based networks. Brain Connectivity 2011, 1: 185-93. PMID: 22433047, PMCID: PMC3621320, DOI: 10.1089/brain.2011.0032.
• A lanthanide complex with dual biosensing properties: CEST (chemical exchange saturation transfer) and BIRDS (biosensor imaging of redundant deviation in shifts) with europium DOTA-tetraglycinate.Coman D, Kiefer GE, Rothman DL, Sherry AD, Hyder F. A lanthanide complex with dual biosensing properties: CEST (chemical exchange saturation transfer) and BIRDS (biosensor imaging of redundant deviation in shifts) with europium DOTA-tetraglycinate. NMR In Biomedicine 2011, 24: 1216-25. PMID: 22020775, PMCID: PMC3267016, DOI: 10.1002/nbm.1677.
• Neurovascular and Neurometabolic Couplings in Dynamic Calibrated fMRI: Transient Oxidative Neuroenergetics for Block-Design and Event-Related Paradigms.Hyder F, Sanganahalli BG, Herman P, Coman D, Maandag NJ, Behar KL, Blumenfeld H, Rothman DL. Neurovascular and Neurometabolic Couplings in Dynamic Calibrated fMRI: Transient Oxidative Neuroenergetics for Block-Design and Event-Related Paradigms. Frontiers In Neuroenergetics 2010, 2 PMID: 20838476, PMCID: PMC2936934, DOI: 10.3389/fnene.2010.00018.
• Brain temperature by Biosensor Imaging of Redundant Deviation in Shifts (BIRDS): comparison between TmDOTP5- and TmDOTMA-.Coman D, Trubel HK, Hyder F. Brain temperature by Biosensor Imaging of Redundant Deviation in Shifts (BIRDS): comparison between TmDOTP5- and TmDOTMA-. NMR In Biomedicine 2010, 23: 277-85. PMID: 19957287, PMCID: PMC2843767, DOI: 10.1002/nbm.1461.
• Brain temperature and pH measured by (1)H chemical shift imaging of a thulium agent.Coman D, Trubel HK, Rycyna RE, Hyder F. Brain temperature and pH measured by (1)H chemical shift imaging of a thulium agent. NMR In Biomedicine 2009, 22: 229-39. PMID: 19130468, PMCID: PMC2735415, DOI: 10.1002/nbm.1312.
• Energetics of neuronal signaling and fMRI activity.Maandag NJ, Coman D, Sanganahalli BG, Herman P, Smith AJ, Blumenfeld H, Shulman RG, Hyder F. Energetics of neuronal signaling and fMRI activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2007, 104: 20546-51. PMID: 18079290, PMCID: PMC2154468, DOI: 10.1073/pnas.0709515104.
• A nuclear magnetic resonance investigation of the energetics of basepair opening pathways in DNA.Coman D, Russu IM. A nuclear magnetic resonance investigation of the energetics of basepair opening pathways in DNA. Biophysical Journal 2005, 89: 3285-92. PMID: 16126830, PMCID: PMC1366824, DOI: 10.1529/biophysj.105.065763.
• Base pair opening in three DNA-unwinding elements.Coman D, Russu IM. Base pair opening in three DNA-unwinding elements. The Journal Of Biological Chemistry 2005, 280: 20216-21. PMID: 15784615, DOI: 10.1074/jbc.M502773200.
• Site-resolved stabilization of a DNA triple helix by magnesium ions.Coman D, Russu IM. Site-resolved stabilization of a DNA triple helix by magnesium ions. Nucleic Acids Research 2004, 32: 878-83. PMID: 14769945, PMCID: PMC373380, DOI: 10.1093/nar/gkh228.
• Imaging Extracellular Acidification and Immune Activation in Cancer.Hyder F, Coman D. Imaging Extracellular Acidification and Immune Activation in Cancer. Current Opinion In Biomedical Engineering 2021, 18 PMID: 33997581, PMCID: PMC8115219, DOI: 10.1016/j.cobme.2021.100278.
• Publisher Correction: Imaging the transmembrane and transendothelial sodium gradients in gliomas.Khan MH, Walsh JJ, Mihailović JM, Mishra SK, Coman D, Hyder F. Publisher Correction: Imaging the transmembrane and transendothelial sodium gradients in gliomas. Scientific Reports 2021, 11: 12463. PMID: 34103626, PMCID: PMC8187420, DOI: 10.1038/s41598-021-91581-w.
• Site-resolved energetics in DNA triple helices containing G*TA and T*CG triads.Coman D, Russu IM. Site-resolved energetics in DNA triple helices containing G*TA and T*CG triads. Biochemistry 2002, 41: 4407-14. PMID: 11914088, DOI: 10.1021/bi011832s.
• Probing hydrogen bonding in a DNA triple helix using protium-deuterium fractionation factors.Coman D, Russu IM. Probing hydrogen bonding in a DNA triple helix using protium-deuterium fractionation factors. Journal Of The American Chemical Society 2003, 125: 6626-7. PMID: 12769560, DOI: 10.1021/ja034223b.
• Diffusion weighted imaging as a biomarker of retinoic acid induced myelomeningocele.Maassel N, Farrelly J, Coman D, Freedman-Weiss M, Ahle S, Ullrich S, Yung N, Hyder F, Stitelman D. Diffusion weighted imaging as a biomarker of retinoic acid induced myelomeningocele. PloS One 2021, 16: e0253583. PMID: 34191842, PMCID: PMC8244849, DOI: 10.1371/journal.pone.0253583.
• Imaging Hallmarks of the Tumor Microenvironment in Glioblastoma Progression.Walsh JJ, Parent M, Akif A, Adam LC, Maritim S, Mishra SK, Khan MH, Coman D, Hyder F. Imaging Hallmarks of the Tumor Microenvironment in Glioblastoma Progression. Frontiers In Oncology 2021, 11: 692650. PMID: 34513675, PMCID: PMC8426346, DOI: 10.3389/fonc.2021.692650.
• Renal plasticity revealed through reversal of polycystic kidney disease in mice.Dong K, Zhang C, Tian X, Coman D, Hyder F, Ma M, Somlo S. Renal plasticity revealed through reversal of polycystic kidney disease in mice. Nature Genetics 2021, 53: 1649-1663. PMID: 34635846, DOI: 10.1038/s41588-021-00946-4.
• Preimplantation factor modulates oligodendrocytes by H19-induced demethylation of NCOR2.Spinelli M, Boucard C, Ornaghi S, Schoeberlein A, Irene K, Coman D, Hyder F, Zhang L, Haesler V, Bordey A, Barnea E, Paidas M, Surbek D, Mueller M. Preimplantation factor modulates oligodendrocytes by H19-induced demethylation of NCOR2. JCI Insight 2021, 6 PMID: 34676826, PMCID: PMC8564895, DOI: 10.1172/jci.insight.132335.
• Comparison of metabolic and immunologic responses to transarterial chemoembolization with different chemoembolic regimens in a rabbit VX2 liver tumor model.Doemel LA, Santana JG, Savic LJ, Gaupp FML, Borde T, Petukhova-Greenstein A, Kucukkaya AS, Schobert IT, Hamm CA, Gebauer B, Walsh JJ, Rexha I, Hyder F, Lin M, Madoff DC, Schlachter T, Chapiro J, Coman D. Comparison of metabolic and immunologic responses to transarterial chemoembolization with different chemoembolic regimens in a rabbit VX2 liver tumor model. European Radiology 2022, 32: 2437-2447. PMID: 34718844, DOI: 10.1007/s00330-021-08337-3.
• High-resolution pH imaging using ratiometric chemical exchange saturation transfer combined with biosensor imaging of redundant deviation in shifts featuring paramagnetic DOTA-tetraglycinate agents.Mihailovic JM, Huang Y, Walsh JJ, Khan MH, Mishra SK, Samuels S, Hyder F, Coman D. High-resolution pH imaging using ratiometric chemical exchange saturation transfer combined with biosensor imaging of redundant deviation in shifts featuring paramagnetic DOTA-tetraglycinate agents. NMR In Biomedicine 2022, 35: e4658. PMID: 34837412, DOI: 10.1002/nbm.4658.
• Methylated tetra-amide derivatives of paramagnetic complexes for magnetic resonance biosensing with both BIRDS and CEST.Zakaria ABM, Huang Y, Coman D, Mishra SK, Mihailovic JM, Maritim S, Rojas-Quijano FA, Jurek P, Kiefer GE, Hyder F. Methylated tetra-amide derivatives of paramagnetic complexes for magnetic resonance biosensing with both BIRDS and CEST. NMR In Biomedicine 2021, e4687. PMID: 34970801, DOI: 10.1002/nbm.4687.
• Comparison of Lanthanide Macrocyclic Complexes as 23Na NMR Sensors.Khan MH, Mishra SK, Zakaria ABM, Mihailović JM, Coman D, Hyder F. Comparison of Lanthanide Macrocyclic Complexes as 23Na NMR Sensors. Analytical Chemistry 2022, 94: 2536-2545. PMID: 35073049, DOI: 10.1021/acs.analchem.1c04432.
• Brain-targeting, acid-responsive antioxidant nanoparticles for stroke treatment and drug delivery.Zhang S, Peng B, Chen Z, Yu J, Deng G, Bao Y, Ma C, Du F, Sheu WC, Kimberly WT, Simard JM, Coman D, Chen Q, Hyder F, Zhou J, Sheth KN. Brain-targeting, acid-responsive antioxidant nanoparticles for stroke treatment and drug delivery. Bioactive Materials 2022, 16: 57-65. PMID: 35386312, PMCID: PMC8958421, DOI: 10.1016/j.bioactmat.2022.02.033.