Curtis Jamison Perry, MD, PhD
Clinical Fellow
Research & Publications
Biography
News
Locations
Coauthors
Selected Publications
- Clinical predictors of longer survival in patients with BRAF V600 -mutated metastatic melanoma receiving immunotherapy prior to BRAF/MEK inhibition in the metastatic setting.Kahn A, Perry C, Etts K, Kluger H, Sznol M. Clinical predictors of longer survival in patients with BRAF V600 -mutated metastatic melanoma receiving immunotherapy prior to BRAF/MEK inhibition in the metastatic setting. Journal Of Clinical Oncology 2022, 40: 9555-9555. DOI: 10.1200/jco.2022.40.16_suppl.9555.
- A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non–Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1Weiss SA, Djureinovic D, Jessel S, Krykbaeva I, Zhang L, Jilaveanu L, Ralabate A, Johnson B, Levit NS, Anderson G, Zelterman D, Wei W, Mahajan A, Trifan O, Bosenberg M, Kaech SM, Perry CJ, Damsky W, Gettinger S, Sznol M, Hurwitz M, Kluger HM. A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non–Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1. Clinical Cancer Research 2021, 27: 4757-4767. PMID: 34140403, PMCID: PMC9236708, DOI: 10.1158/1078-0432.ccr-21-0903.
- LB1122 Myeloid targeting in combination with PD1 inhibition boosts anti-tumor immunity in melanomaKrykbaeva I, Damsky W, Turner N, Perry C, Kluger H, Bosenberg M. LB1122 Myeloid targeting in combination with PD1 inhibition boosts anti-tumor immunity in melanoma. Journal Of Investigative Dermatology 2019, 139: b19. DOI: 10.1016/j.jid.2019.06.089.
- Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumorsAyeni D, Miller B, Kuhlmann A, Ho PC, Robles-Oteiza C, Gaefele M, Levy S, de Miguel FJ, Perry C, Guan T, Krystal G, Lockwood W, Zelterman D, Homer R, Liu Z, Kaech S, Politi K. Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors. Journal For ImmunoTherapy Of Cancer 2019, 7: 172. PMID: 31291990, PMCID: PMC6617639, DOI: 10.1186/s40425-019-0643-8.
- B cell depletion or absence does not impede anti-tumor activity of PD-1 inhibitorsDamsky W, Jilaveanu L, Turner N, Perry C, Zito C, Tomayko M, Leventhal J, Herold K, Meffre E, Bosenberg M, Kluger HM. B cell depletion or absence does not impede anti-tumor activity of PD-1 inhibitors. Journal For ImmunoTherapy Of Cancer 2019, 7: 153. PMID: 31200747, PMCID: PMC6567557, DOI: 10.1186/s40425-019-0613-1.
- Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon CancerWang Y, Nasiri AR, Damsky WE, Perry CJ, Zhang XM, Rabin-Court A, Pollak MN, Shulman GI, Perry RJ. Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer. Cell Reports 2018, 24: 47-55. PMID: 29972790, PMCID: PMC6056247, DOI: 10.1016/j.celrep.2018.06.008.
- Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunityPerry CJ, Muñoz-Rojas AR, Meeth KM, Kellman LN, Amezquita RA, Thakral D, Du VY, Wang JX, Damsky W, Kuhlmann AL, Sher JW, Bosenberg M, Miller-Jensen K, Kaech SM. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. Journal Of Experimental Medicine 2018, 215: 877-893. PMID: 29436395, PMCID: PMC5839759, DOI: 10.1084/jem.20171435.
- IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airwaysYeon SM, Halim L, Chandele A, Perry CJ, Kim SH, Kim SU, Byun Y, Yuk SH, Kaech SM, Jung YW. IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways. Scientific Reports 2017, 7: 11155. PMID: 28894184, PMCID: PMC5593957, DOI: 10.1038/s41598-017-11492-7.
- UV‐induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma modelWang J, Perry CJ, Meeth K, Thakral D, Damsky W, Micevic G, Kaech S, Blenman K, Bosenberg M. UV‐induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model. Pigment Cell & Melanoma Research 2017, 30: 428-435. PMID: 28379630, PMCID: PMC5820096, DOI: 10.1111/pcmr.12591.
- 766 Exposure to ultraviolet light enhances anti-tumor immunity and response to immunotherapy in a mouse model of melanomaDamsky W, Wang J, Perry C, Meeth K, Kaech S, Bosenberg M. 766 Exposure to ultraviolet light enhances anti-tumor immunity and response to immunotherapy in a mouse model of melanoma. Journal Of Investigative Dermatology 2017, 137: s132. DOI: 10.1016/j.jid.2017.02.791.
- P3.02c-088 Acquired Resistance to Programmed Death-1 Axis Inhibitors in Non-Small Cell Lung Cancer (NSCLC) Topic: IT BiomarkersChoi J, Sowell R, Truini A, Schalper K, Wurtz A, Cai G, Perry C, Datar I, Hastings K, Melnick M, Kaftan E, Kavathas P, Kaech S, Rimm D, Goldberg S, Chiang A, Lifton R, Chen L, Herbst R, Politi K, Gettinger S. P3.02c-088 Acquired Resistance to Programmed Death-1 Axis Inhibitors in Non-Small Cell Lung Cancer (NSCLC) Topic: IT Biomarkers. Journal Of Thoracic Oncology 2017, 12: s1331-s1332. DOI: 10.1016/j.jtho.2016.11.1884.
- CCR7 expression alters memory CD8 T-cell homeostasis by regulating occupancy in IL-7– and IL-15–dependent nichesJung YW, Kim HG, Perry CJ, Kaech SM. CCR7 expression alters memory CD8 T-cell homeostasis by regulating occupancy in IL-7– and IL-15–dependent niches. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 8278-8283. PMID: 27385825, PMCID: PMC4961181, DOI: 10.1073/pnas.1602899113.
- 616 UV-induced somatic mutations elicit a functional T cell response and tumor regression in BRAFV600E, CDKN2A-/-, PTEN-/- melanoma modelWang J, Meeth K, Perry C, Ventura A, Kaech S, Edelson R, Bosenberg M. 616 UV-induced somatic mutations elicit a functional T cell response and tumor regression in BRAFV600E, CDKN2A-/-, PTEN-/- melanoma model. Journal Of Investigative Dermatology 2016, 136: s109. DOI: 10.1016/j.jid.2016.02.656.
- Abstract A083: Modulation of the immune system as a strategy to treat EGFR mutant lung adenocarcinomaAyeni D, Ho P, Perry C, Kaech S, Politi K. Abstract A083: Modulation of the immune system as a strategy to treat EGFR mutant lung adenocarcinoma. Cancer Immunology Research 2016, 4: a083-a083. DOI: 10.1158/2326-6074.cricimteatiaacr15-a083.
- Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infectionChen JH, Perry CJ, Tsui YC, Staron MM, Parish IA, Dominguez CX, Rosenberg DW, Kaech SM. Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection. Nature Medicine 2015, 21: 327-334. PMID: 25799228, PMCID: PMC4505619, DOI: 10.1038/nm.3831.
- Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 DiabetesPerry RJ, Camporez JP, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, Birnbaum MJ, Davis RJ, Cline GW, Petersen KF, Shulman GI. Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes. Cell 2015, 160: 745-758. PMID: 25662011, PMCID: PMC4498261, DOI: 10.1016/j.cell.2015.01.012.
- The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic InfectionStaron MM, Gray SM, Marshall HD, Parish IA, Chen JH, Perry CJ, Cui G, Li MO, Kaech SM. The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection. Immunity 2014, 41: 802-814. PMID: 25464856, PMCID: PMC4270830, DOI: 10.1016/j.immuni.2014.10.013.
- Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1Parish IA, Marshall HD, Staron MM, Lang PA, Brüstle A, Chen JH, Cui W, Tsui YC, Perry C, Laidlaw BJ, Ohashi PS, Weaver CT, Kaech SM. Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1. Journal Of Clinical Investigation 2014, 124: 3455-3468. PMID: 25003188, PMCID: PMC4109559, DOI: 10.1172/jci66108.