Christine Ko, MD
Professor of Dermatology and Pathology
Research & Publications
Biography
News
Research Summary
I am studying skin cancer, particularly squamous cell carcinoma and keratoacanthoma. I am also interested in clinical-pathologic correlation and biomarkers of skin disease.
Specialized Terms: Adnexal tumors; Benign and malignant epidermal tumors
Extensive Research Description
I tend to focus on how to distinguish between diseases and disorders that may present in a similar fashion clinically and/or microscopically. I have published papers as well as books in clinical dermatology and dermatopathology (Dermatology: Visual Recognition and Case Reviews, Dermatology Essentials, Dermatopathology: Diagnosis by First Impression).
I am also interested in mechanisms of carcinogenesis, particularly as they relate to squamous cell carcinoma of the skin and a spontaneously regressing tumor called keratoacanthoma.
Coauthors
Research Interests
Carcinoma, Squamous Cell; Dermatology; Epidermis; Keratoacanthoma; Pathology; Skin Neoplasms; Neoplasms, Adnexal and Skin Appendage; Vascular Neoplasms
Research Images
Selected Publications
- Perniosis during the COVID-19 pandemic: Negative anti-SARS-CoV-2 immunohistochemistry in six patients and comparison to perniosis before the emergence of SARS-CoV-2.Ko CJ, Harigopal M, Damsky W, Gehlhausen JR, Bosenberg M, Patrignelli R, McNiff JM. Perniosis during the COVID-19 pandemic: Negative anti-SARS-CoV-2 immunohistochemistry in six patients and comparison to perniosis before the emergence of SARS-CoV-2. Journal Of Cutaneous Pathology 2020, 47: 997-1002. PMID: 32745281, PMCID: PMC7436569, DOI: 10.1111/cup.13830.
- Discordant anti-SARS-CoV-2 spike protein and RNA staining in cutaneous perniotic lesions suggests endothelial deposition of cleaved spike protein.Ko CJ, Harigopal M, Gehlhausen JR, Bosenberg M, McNiff JM, Damsky W. Discordant anti-SARS-CoV-2 spike protein and RNA staining in cutaneous perniotic lesions suggests endothelial deposition of cleaved spike protein. Journal Of Cutaneous Pathology 2021, 48: 47-52. PMID: 32895985, DOI: 10.1111/cup.13866.
- Visual perception, cognition, and error in dermatologic diagnosis: Key cognitive principles.Ko CJ, Braverman I, Sidlow R, Lowenstein EJ. Visual perception, cognition, and error in dermatologic diagnosis: Key cognitive principles. Journal Of The American Academy Of Dermatology 2019, 81: 1227-1234. PMID: 30797839, DOI: 10.1016/j.jaad.2018.10.082.
- Visual perception, cognition, and error in dermatologic diagnosis: Diagnosis and error.Lowenstein EJ, Sidlow R, Ko C. Visual perception, cognition, and error in dermatologic diagnosis: Diagnosis and error. Journal Of The American Academy Of Dermatology 2019, 81: 1237-1245. PMID: 30797841, DOI: 10.1016/j.jaad.2018.12.072.
- A detailed analysis of the distribution, morphology, and histopathology of complex purpura in hospitalized patients: A case series of 68 patients.Gehlhausen JR, Wetter DA, Nelson C, Ramachandran S, McNiff JM, Ko CJ. A detailed analysis of the distribution, morphology, and histopathology of complex purpura in hospitalized patients: A case series of 68 patients. Journal Of The American Academy Of Dermatology 2021, 84: 1188-1196. PMID: 32376433, DOI: 10.1016/j.jaad.2020.04.149.
- Histopathologic findings characteristic of CARD14-associated papulosquamous eruption.Ring NG, Craiglow BG, Panse G, Antaya RJ, Ashack K, Ashack R, Faith EF, Paller AS, McNiff JM, Choate KA, Ko CJ. Histopathologic findings characteristic of CARD14-associated papulosquamous eruption. Journal Of Cutaneous Pathology 2020, 47: 425-430. PMID: 31849081, DOI: 10.1111/cup.13633.
- Cutaneous squamous cell carcinomas of the lower extremity: a distinct subset of squamous cell carcinomas.Kim C, Ko CJ, Leffell DJ. Cutaneous squamous cell carcinomas of the lower extremity: a distinct subset of squamous cell carcinomas. Journal Of The American Academy Of Dermatology 2014, 70: 70-4. PMID: 24210370, DOI: 10.1016/j.jaad.2013.09.026.
- Keratoacanthoma Shares Driver Mutations with Cutaneous Squamous Cell Carcinoma.Lim YH, Fisher JM, Bosenberg MW, Choate KA, Ko CJ. Keratoacanthoma Shares Driver Mutations with Cutaneous Squamous Cell Carcinoma. The Journal Of Investigative Dermatology 2016, 136: 1737-1741. PMID: 27283355, DOI: 10.1016/j.jid.2016.04.002.
- Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk.Zito G, Saotome I, Liu Z, Ferro EG, Sun TY, Nguyen DX, Bilguvar K, Ko CJ, Greco V. Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk. Nature Communications 2014, 5: 3543. PMID: 24667544, PMCID: PMC3974217, DOI: 10.1038/ncomms4543.