Research & Publications
Our laboratory studies the agents of human malaria and babesiosis. The primary objectives of our research program are to identify new cellular mechanisms that could be targeted for the development of selective new therapies. Our laboratory discovered several genes that play critical roles in development, differentiation and survival of Plasmodium and Babesia parasites. We combine various techniques in the fields of biochemistry, structural biology, genetics and medicinal chemistry to identify inhibitors with potent activity against these parasites.
Our therapy program builds upon the findings of our basic research program. There are two main topics investigated in this program: vaccine development and drug discovery.
Babesiosis; Malaria; Opportunistic Infections; Protozoan Infections; Infectious Disease Medicine
- Plasmodium lipids: Metabolism and FunctionHenri J. Vial and Choukri Ben Mamoun. Plasmodium lipids: Metabolism and Function. Molecular Approaches to Malaria, Edited by I. W. Sherman (ed.). 2005 ASM Press, Washington, D. C. Chapter 17: 327 – 352.