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Choukri Ben Mamoun, PhD

Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis

Contact Information

Choukri Ben Mamoun, PhD

Mailing Address

  • Infectious Diseases

    PO Box 208056, 333 Cedar Street

    New Haven, CT 06520-8056

    United States

Research Summary

Basic Research
Our laboratory studies the agents of human malaria and babesiosis. The primary objectives of our research program are to identify new cellular mechanisms that could be targeted for the development of selective new therapies. Our laboratory discovered several genes that play critical roles in development, differentiation and survival of Plasmodium and Babesia parasites. We combine various techniques in the fields of biochemistry, structural biology, genetics and medicinal chemistry to identify inhibitors with potent activity against these parasites.

Therapy Program
Our therapy program builds upon the findings of our basic research program. There are two main topics investigated in this program: vaccine development and drug discovery.

Coauthors

Research Interests

Babesiosis; Malaria; Opportunistic Infections; Protozoan Infections; Infectious Disease Medicine

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Selected Publications

  • Plasmodium lipids: Metabolism and FunctionHenri J. Vial and Choukri Ben Mamoun. Plasmodium lipids: Metabolism and Function. Molecular Approaches to Malaria, Edited by I. W. Sherman (ed.). 2005 ASM Press, Washington, D. C. Chapter 17: 327 – 352.