Charles Duncan, MD, FAANS
Research & Publications
Biography
News
Research Summary
Development of cerebral blood flow measurement systems for immature brain by positron emission tomography, the prevention of intraventricular and germinal matrix hemorrhage in the premature infant by basic and multicenter clinical trials, basic investigations into the adaptive mechanisms of developing brain to injury, and the development of endoscopic surgery in the very young.
Specialized Terms: Adaptation of the developing brain to injury
Extensive Research Description
Dr. Duncan's research activities have included the development of cerebral blood flow measurement systems for immature brain by positron emission tomography, the prevention of intraventricular and germinal matrix hemorrhage in the premature infant by basic and multicenter clinical trials, basic investigations into the adaptive mechanisms of developing brain to injury, and the development of endoscopic surgery in the very young
Coauthors
Research Interests
Brain Injuries; Cerebral Arteries; Infant; Neurosurgery; Pediatrics
Selected Publications
- Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus.Jin SC, Dong W, Kundishora AJ, Panchagnula S, Moreno-De-Luca A, Furey CG, Allocco AA, Walker RL, Nelson-Williams C, Smith H, Dunbar A, Conine S, Lu Q, Zeng X, Sierant MC, Knight JR, Sullivan W, Duy PQ, DeSpenza T, Reeves BC, Karimy JK, Marlier A, Castaldi C, Tikhonova IR, Li B, Peña HP, Broach JR, Kabachelor EM, Ssenyonga P, Hehnly C, Ge L, Keren B, Timberlake AT, Goto J, Mangano FT, Johnston JM, Butler WE, Warf BC, Smith ER, Schiff SJ, Limbrick DD, Heuer G, Jackson EM, Iskandar BJ, Mane S, Haider S, Guclu B, Bayri Y, Sahin Y, Duncan CC, Apuzzo MLJ, DiLuna ML, Hoffman EJ, Sestan N, Ment LR, Alper SL, Bilguvar K, Geschwind DH, Günel M, Lifton RP, Kahle KT. Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus. Nature Medicine 2020, 26: 1754-1765. PMID: 33077954, PMCID: PMC7871900, DOI: 10.1038/s41591-020-1090-2.
- Long-Term Neurocognitive Outcomes in Sagittal Synostosis: The Impact of Reoperation.Chuang C, Chaunzwa TL, Wu R, Singh A, Patel A, Yang JF, Hashim PW, Travieso R, Terner JS, Mayes LC, Duncan CC, Jane JA, Lin KY, Bridgett DJ, Persing JA. Long-Term Neurocognitive Outcomes in Sagittal Synostosis: The Impact of Reoperation. The Journal Of Craniofacial Surgery 2021, 32: 58-61. PMID: 33394632, DOI: 10.1097/SCS.0000000000006909.
- Functional Network Development in Sagittal Craniosynostosis Treated With Whole Vault Cranioplasty.Cabrejo R, Lacadie C, Sun A, Chuang C, Yang J, Brooks E, Beckett J, Eilbott J, Gabrick K, Steinbacher D, Duncan C, DiLuna M, Alperovich M, Pelphrey K, Ventola P, Constable T, Persing JA. Functional Network Development in Sagittal Craniosynostosis Treated With Whole Vault Cranioplasty. The Journal Of Craniofacial Surgery 2021, 32: 1721-1726. PMID: 33534301, DOI: 10.1097/SCS.0000000000007505.