Bryan Young, MD/PhD, FACC
Lecturer
Research & Publications
Biography
News
Coauthors
Research Interests
Amyloidosis; Cardiovascular Agents; Cardiovascular Diseases; Coronary Disease; Molecular Biology; Cardiomyopathies; Nuclear Medicine; Radionuclide Imaging; Sarcoidosis; Cardiac Imaging Techniques; COVID-19
Selected Publications
- Cytokine Signaling and Matrix Remodeling Pathways Associated with Cardiac Sarcoidosis Disease Activity Defined Using FDG PET Imaging.Young BD, Moreland H, Oatmen KE, Freeburg LA, Shahab Z, Herzog E, Miller EJ, Spinale FG. Cytokine Signaling and Matrix Remodeling Pathways Associated with Cardiac Sarcoidosis Disease Activity Defined Using FDG PET Imaging. International Heart Journal 2021, 62: 1096-1105. PMID: 34544982, DOI: 10.1536/ihj.21-164.
- Non-steroidal treatment of cardiac sarcoidosis: A systematic review.Gallegos C, Oikonomou EK, Grimshaw A, Gulati M, Young BD, Miller EJ. Non-steroidal treatment of cardiac sarcoidosis: A systematic review. International Journal Of Cardiology. Heart & Vasculature 2021, 34: 100782. PMID: 33997256, PMCID: PMC8105294, DOI: 10.1016/j.ijcha.2021.100782.
- Potential novel imaging targets of inflammation in cardiac sarcoidosis.Park J, Young BD, Miller EJ. Potential novel imaging targets of inflammation in cardiac sarcoidosis. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34734365, DOI: 10.1007/s12350-021-02838-w.
- Treatment of Multiorgan Sarcoidosis With Tofacitinib.Damsky W, Young BD, Sloan B, Miller EJ, Obando JA, King B. Treatment of Multiorgan Sarcoidosis With Tofacitinib. ACR Open Rheumatology 2020, 2: 106-109. PMID: 31916703, PMCID: PMC7011417, DOI: 10.1002/acr2.11112.
- Repeatability and Optimization of FDG Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis.Alvi RM, Young BD, Shahab Z, Pan H, Winkler J, Herzog E, Miller EJ. Repeatability and Optimization of FDG Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis. JACC. Cardiovascular Imaging 2019, 12: 1284-1287. PMID: 30846271, DOI: 10.1016/j.jcmg.2019.01.011.
- Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.Ceneri N, Zhao L, Young BD, Healy A, Coskun S, Vasavada H, Yarovinsky TO, Ike K, Pardi R, Qin L, Qin L, Tellides G, Hirschi K, Meadows J, Soufer R, Chun HJ, Sadeghi M, Bender JR, Morrison AR. Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production. Arteriosclerosis, Thrombosis, And Vascular Biology 2017, 37: 328-340. PMID: 27834690, PMCID: PMC5269510, DOI: 10.1161/ATVBAHA.116.308507.
- Relative predictive value of lung cancer screening CT versus myocardial perfusion attenuation correction CT in the evaluation of coronary calcium.Bailey G, Healy A, Young BD, Sharma E, Meadows J, Chun HJ, Wu WC, Choudhary G, Morrison AR. Relative predictive value of lung cancer screening CT versus myocardial perfusion attenuation correction CT in the evaluation of coronary calcium. PloS One 2017, 12: e0175678. PMID: 28437443, PMCID: PMC5402939, DOI: 10.1371/journal.pone.0175678.
- Endothelial estrogen receptor isoforms and cardiovascular disease.Kim KH, Young BD, Bender JR. Endothelial estrogen receptor isoforms and cardiovascular disease. Molecular And Cellular Endocrinology 2014, 389: 65-70. PMID: 24530925, PMCID: PMC4040324, DOI: 10.1016/j.mce.2014.02.001.
- Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.Morrison AR, Yarovinsky TO, Young BD, Moraes F, Ross TD, Ceneri N, Zhang J, Zhuang ZW, Sinusas AJ, Pardi R, Schwartz MA, Simons M, Bender JR. Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis. The Journal Of Experimental Medicine 2014, 211: 1957-68. PMID: 25180062, PMCID: PMC4172219, DOI: 10.1084/jem.20132130.
- The future is now: frontiers on display at Yale-NAVBO cardiovascular inflammation and remodeling symposium 2014.Wong A, Young B. The future is now: frontiers on display at Yale-NAVBO cardiovascular inflammation and remodeling symposium 2014. The Yale Journal Of Biology And Medicine 2014, 87: 593-9. PMID: 25506292, PMCID: PMC4257044.
- Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes.Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN, Verdin E. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. Journal Of Immunology (Baltimore, Md. : 1950) 2011, 186: 4782-93. PMID: 21398603, DOI: 10.4049/jimmunol.1001179.
- Histone Deacetylases in Cardiovascular Development and DiseaseYoung BD, Olson EN. Histone Deacetylases in Cardiovascular Development and Disease. In: Rosenthal N and Harvey R, ed. Heart Development. 2nd Edition. (2010). London: Academic Press.
- Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10.Chang S, Young BD, Li S, Qi X, Richardson JA, Olson EN. Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell 2006, 126: 321-34. PMID: 16873063, DOI: 10.1016/j.cell.2006.05.040.
- Multimodality Imaging in the Diagnosis of Prosthetic Valve Endocarditis: A Brief Review.Eder MD, Upadhyaya K, Park J, Ringer M, Malinis M, Young BD, Sugeng L, Hur DJ. Multimodality Imaging in the Diagnosis of Prosthetic Valve Endocarditis: A Brief Review. Frontiers In Cardiovascular Medicine 2021, 8: 750573. PMID: 34988125, PMCID: PMC8720921, DOI: 10.3389/fcvm.2021.750573.
- Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis.Damsky W, Wang A, Kim DJ, Young BD, Singh K, Murphy MJ, Daccache J, Clark A, Ayasun R, Ryu C, McGeary MK, Odell ID, Fazzone-Chettiar R, Pucar D, Homer R, Gulati M, Miller EJ, Bosenberg M, Flavell RA, King B. Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis. Nature Communications 2022, 13: 3140. PMID: 35668129, DOI: 10.1038/s41467-022-30615-x.