Brian Weiss, PhD

• Alessandra Orfanó
• Serap Aksoy

Symbiosis; Trypanosomiasis; Tsetse Flies; Host-Pathogen Interactions

Genetics, Genomics, Epigenetics; Infectious Diseases; Vector Biology; Microbiome

• Identification and characterization of genes differentially expressed in the testis/vas deferens of the fed male tick, Amblyomma hebraeum.Weiss BL, Stepczynski JM, Wong P, Kaufman WR. Identification and characterization of genes differentially expressed in the testis/vas deferens of the fed male tick, Amblyomma hebraeum. Insect Biochemistry And Molecular Biology 2002, 32: 785-93. PMID: 12044495, DOI: 10.1016/s0965-1748(01)00161-8.
• Two feeding-induced proteins from the male gonad trigger engorgement of the female tick Amblyomma hebraeum.Weiss BL, Kaufman WR. Two feeding-induced proteins from the male gonad trigger engorgement of the female tick Amblyomma hebraeum. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 5874-9. PMID: 15069191, PMCID: PMC395891, DOI: 10.1073/pnas.0307529101.
• The relationship between 'critical weight' and 20-hydroxyecdysone in the female ixodid tick, Amblyomma hebraeum.Weiss BL, Reuben Kaufman W. The relationship between 'critical weight' and 20-hydroxyecdysone in the female ixodid tick, Amblyomma hebraeum. Journal Of Insect Physiology 2001, 47: 1261-1267. PMID: 12770177, DOI: 10.1016/s0022-1910(01)00112-3.
• Nitric oxide produced by a novel nitric oxide synthase isoform is necessary for gonadotropin-releasing hormone-induced growth hormone secretion via a cGMP-dependent mechanism.Uretsky AD, Weiss BL, Yunker WK, Chang JP. Nitric oxide produced by a novel nitric oxide synthase isoform is necessary for gonadotropin-releasing hormone-induced growth hormone secretion via a cGMP-dependent mechanism. Journal Of Neuroendocrinology 2003, 15: 667-76. PMID: 12787051, DOI: 10.1046/j.1365-2826.2003.01046.x.
• Correction: Colonization of the tsetse fly midgut with commensal Kosakonia cowanii Zambiae inhibits trypanosome infection establishment.Weiss BL, Maltz MA, Vigneron A, Wu Y, Walter KS, O'Neill MB, Wang J, Aksoy S. Correction: Colonization of the tsetse fly midgut with commensal Kosakonia cowanii Zambiae inhibits trypanosome infection establishment. PLoS Pathogens 2019, 15: e1007688. PMID: 30958865, PMCID: PMC6453440, DOI: 10.1371/journal.ppat.1007688.
• Enhancing tsetse fly refractoriness to trypanosome infection--a new IAEA coordinated research project.Van Den Abbeele J, Bourtzis K, Weiss B, Cordón-Rosales C, Miller W, Abd-Alla AM, Parker A. Enhancing tsetse fly refractoriness to trypanosome infection--a new IAEA coordinated research project. Journal Of Invertebrate Pathology 2013, 112 Suppl: S142-7. PMID: 22841950, DOI: 10.1016/j.jip.2012.07.020.
• Paratransgenic manipulation of a tsetse microRNA alters the physiological homeostasis of the fly's midgut environment.Yang L, Weiss BL, Williams AE, Aksoy E, de Silva Orfano A, Son JH, Wu Y, Vigneron A, Karakus M, Aksoy S. Paratransgenic manipulation of a tsetse microRNA alters the physiological homeostasis of the fly's midgut environment. PLoS Pathogens 2021, 17: e1009475. PMID: 34107000, PMCID: PMC8216540, DOI: 10.1371/journal.ppat.1009475.
• Infection with endosymbiotic Spiroplasma disrupts tsetse (Glossina fuscipes fuscipes) metabolic and reproductive homeostasis.Son JH, Weiss BL, Schneider DI, Dera KM, Gstöttenmayer F, Opiro R, Echodu R, Saarman NP, Attardo GM, Onyango M, Abd-Alla AMM, Aksoy S. Infection with endosymbiotic Spiroplasma disrupts tsetse (Glossina fuscipes fuscipes) metabolic and reproductive homeostasis. PLoS Pathogens 2021, 17: e1009539. PMID: 34529715, PMCID: PMC8478229, DOI: 10.1371/journal.ppat.1009539.
• Metabolic interactions between disease-transmitting vectors and their microbiota.Song X, Zhong Z, Gao L, Weiss BL, Wang J. Metabolic interactions between disease-transmitting vectors and their microbiota. Trends In Parasitology 2022, 38: 697-708. PMID: 35643853, DOI: 10.1016/j.pt.2022.05.002.