Robert I. White Jr, MD
Professor Emeritus of Radiology and Biomedical Imaging
Research & Publications
Biography
News
Research Summary
We are concentrating on the 5 organ systems, innovolved by hereditary hemorrhagic telangiectasia. See www.hhtavm.org
We are actively researching exercise stress testing in the follow-up of patients with pulmonary arteriovenous malformations.
Extensive Research Description
Dr. Robert I. White Jr.'s research interests include clinical investigation of the new diagnostic and therapeutic methods for treating vascular malformations. Among patients with congenital vascular malformations, there exists an uncommon autosomal dominant type referred to as Osler-Weber-Rendu Syndrome or more properly Hereditary Hemorrhagic Telangiectasia (HHT). The clinical manifestations of this disorder are due to direct artery-to-vein connections referred to as arteriovenous malformation which occur in nose, brain, lung and boweland to lead to abnormal bleeding and other physiological consequences. Dr. White's group is concluding a number of ongoing collaborative projects with the gastrointestinal and pulmonary sections of medicine, and the Department of Neurology, Neurosurgery and Otolaryngology.We are embarking on a new area of study: reproduciability and efficacy of exercise oximetry in assessing children and adults with pulmonary arteriovenous malformations. Our first paper appeared in Pediatric Cariology 2009. online version available in pub med.
Coauthors
Research Interests
Health Care
Selected Publications
- Distal Cross-sectional Occlusion Is the “Key” to Treating Pulmonary Arteriovenous MalformationsPollak JS, White RI. Distal Cross-sectional Occlusion Is the “Key” to Treating Pulmonary Arteriovenous Malformations. Journal Of Vascular And Interventional Radiology 2012, 23: 1578-1580. PMID: 23177104, DOI: 10.1016/j.jvir.2012.10.007.
- Brain arteriovenous malformations associated with hereditary hemorrhagic telangiectasia: Gene–phenotype correlationsNishida T, Faughnan ME, Krings T, Chakinala M, Gossage JR, Young WL, Kim H, Pourmohamad T, Henderson KJ, Schrum SD, James M, Quinnine N, Bharatha A, terBrugge KG, White RI. Brain arteriovenous malformations associated with hereditary hemorrhagic telangiectasia: Gene–phenotype correlations. American Journal Of Medical Genetics Part A 2012, 158A: 2829-2834. PMID: 22991266, PMCID: PMC3610331, DOI: 10.1002/ajmg.a.35622.
- The Young's Procedure for Severe Epistaxis from Hereditary Hemorrhagic TelangiectasiaRicher SL, Geisthoff UW, Livada N, Ward PD, Johnson L, Mainka A, Henderson KJ, Maune S, White RI, Ross DA. The Young's Procedure for Severe Epistaxis from Hereditary Hemorrhagic Telangiectasia. American Journal Of Rhinology And Allergy 2012, 26: 401-404. PMID: 23168156, DOI: 10.2500/ajra.2012.26.3809.
- Reproducibility of Oxygen Saturation Monitoring During Six-Minute Walk Test and Exercise Stress Test in Patients with Pulmonary Arteriovenous Malformations Associated With Hereditary Hemorrhagic TelangiectasiaLi W, Niu B, Henderson K, Northrup V, Pollak JS, Trow T, Fahey J, White RI. Reproducibility of Oxygen Saturation Monitoring During Six-Minute Walk Test and Exercise Stress Test in Patients with Pulmonary Arteriovenous Malformations Associated With Hereditary Hemorrhagic Telangiectasia. Pediatric Cardiology 2011, 32: 590-594. PMID: 21336824, DOI: 10.1007/s00246-011-9917-8.
- Hemothorax Due to Rupture of Pulmonary Arteriovenous Malformation An Interventional EmergencyBerg AM, Amirbekian S, Mojibian H, Trow TK, Smith SJ, White RI. Hemothorax Due to Rupture of Pulmonary Arteriovenous Malformation An Interventional Emergency. CHEST Journal 2010, 137: 705-707. PMID: 20202952, DOI: 10.1378/chest.09-0344.
- Overlapping spectra of SMAD4 mutations in juvenile polyposis (JP) and JP-HHT syndrome.Gallione C, Aylsworth AS, Beis J, Berk T, Bernhardt B, Clark RD, Clericuzio C, Danesino C, Drautz J, Fahl J, Fan Z, Faughnan ME, Ganguly A, Garvie J, Henderson K, Kini U, Leedom T, Ludman M, Lux A, Maisenbacher M, Mazzucco S, Olivieri C, Ploos van Amstel JK, Prigoda-Lee N, Pyeritz RE, Reardon W, Vandezande K, Waldman JD, White RI, Williams CA, Marchuk DA. Overlapping spectra of SMAD4 mutations in juvenile polyposis (JP) and JP-HHT syndrome. American Journal Of Medical Genetics. Part A 2010, 152A: 333-9. PMID: 20101697, DOI: 10.1002/ajmg.a.33206.
- 2009 Treatment Guidelines for Hereditary Hemorrhagic TelangiectasiaTrerotola SO, Pyeritz RE, White RI, Picus D, Miller FJ. 2009 Treatment Guidelines for Hereditary Hemorrhagic Telangiectasia. Journal Of Vascular And Interventional Radiology 2009, 21: 179. PMID: 20022766, DOI: 10.1016/j.jvir.2009.10.009.
- International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasiaFaughnan ME, Palda VA, Garcia-Tsao G, Geisthoff UW, McDonald J, Proctor DD, Spears J, Brown DH, Buscarini E, Chesnutt MS, Cottin V, Ganguly A, Gossage JR, Guttmacher AE, Hyland RH, Kennedy SJ, Korzenik J, Mager JJ, Ozanne AP, Piccirillo JF, Picus D, Plauchu H, Porteous ME, Pyeritz RE, Ross DA, Sabba C, Swanson K, Terry P, Wallace MC, Westermann CJ, White RI, Young LH, Zarrabeitia R. International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia. Journal Of Medical Genetics 2009, 48: 73. PMID: 19553198, DOI: 10.1136/jmg.2009.069013.