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Aron Rose, MD

Assistant Clinical Professor, Surgery; Associate Clinical Professor

Research Summary

Research has focused primarily upon identification, medical and surgical treatment options for cataract and glaucoma, the two most common blinding conditions in the world.

Extensive Research Description

Investigator: Open Label One Year Long Study to Evaluate the Long-Term Efficasy, Safety, and Acceptability of 2% Pilasite BID, 1992 Insite Vision.

Investigator: Three Month Study to Compare the Efficacy, Safety, and Tolerability of 0.1% Betasite and 0.5% Betasite to 0.5% Betagan BID in Subjects with Open Angle Glaucoma or Ocular Hypertension, 1992, Insite Vision.

Investigator: Long-Term Safety and Ocular Hypotensive Efficasy of Brimonidine Tartrate

0.2% in Subjects with Open Angle Glaucoma or Ocular Hypertension, 1993 Allergan.

Investigator: A Multi-Center, Randomized, Double-Blind, Parallel Clinical Study to Evaluate the Safety and Efficasy of Metipranolol 0.1% / Pilocarpine 2% BID, Metipranolol 0.3% / Pilocarpine 2% BID, Metipranolol 0.3% BID and Pilocarpine 2% QID for 12 Weeks in the Treatment of Patients with Ocular Hypertension or Glaucoma with Open Iridocorneal Angles, 1995 Bausch & Lomb.

Investigator: A Vehicle Controlled Study Evaluating the Ocular Safety and Efficasy of Ketorolac Tromethamine 0.5% Ophthalmic Solution in Subjects with Inflammation Following Cataract Surgery, 1995 Allergan.

Investigator: A Controlled Double-Masked, Two Period Crossover Study Comparing the Efficasy and Tolerability of 0.5% Timolol Maleate Gel Froming Solution QD vs. 0.5% Levobunolol Hydrochloride BID in Patients with Open Angle Glaucoma or Ocular Hypertension, 1996 Merck.

Investigator: A Controlled Randomized, Double-Masked, Placebo-Controlled Evaluation of the Efficasy of Dorzolamide Hydrochloride Ophthalmic Solution 2% in the Prophylaxis of Elevated Intraocular Pressure After Anterior Segment Laser Surgery, 1996 Merck.

Investigator: A Twelve Month Triple Masked Parallel Group Primary Therapy Study of AL-6221 .00015% and AL-6221 .0004% Compared to Timoptic 0.5% and Xalatan .005% in Patients with Open Angle Glaucoma or Ocular Hypertension, 1997-8 Alcon

Investigator: Three Month Study of the Evaluation of Xalatan When Used as Adjunctive Therapy to Betoptic S Ophthalmic Suspension 0.25% or Timoptic Ophthalmic Solution 0.5%, 1998-9 Alcon

Investigator: Safety and Efficasy of 0.2% Brimonidine Tartrate/0.5% Timolol Combination Twice Daily Compared With 0.5% Timolol Twice Daily or Alphagan Three Times Daily in Patients With Glaucoma or Ocular Hypertension, 2000-2001 Allergan

Investigator: A 48-Month, Mulit-Center, Randomized, Double-Masked, Placebo-Controlled, Clinical Study to Evaluate the Effectiveness and Safety of Oral Memantine in Daily Doses of 20 mg and 10 mg in Patients with Chronic Open-Angle Glaucoma at Risk for Glaucomatous Progression, 2000- 2007

Investigator: Safety and Efficacy of Phacoemulsification: Comparison of Sovereign with Whitestar and Legacy with Advantec and NeoSonix 12/02-4/03

Investigator: Comparative Clinical Trial of Ultrasound Phacoemulsification with and without WhiteStar System 2003

Investigator: Clinical Evaluation of a Lightweight Handpiece for the Sovereign Phacoemulsification System, 2003-2004

Principal Investigator: Thermal Imaging Study Comparing Phacoemulsification with the Sovereign WhiteStar System to the Legacy with AdvanTec and NeoSoniX System. 2004-2005

Investigator: Nepafenac Ophthamlic Suspension 0.1% Compared to Acular LS for Treatment of Inflammation After Cataract Surgery. 2005

Principal Investigator: Comparison of Post Operative Intraocular Inflammation After Standard Cataract Surgery With Either the AMO Sovereign WhiteStar ICE or the Alcon Infinity Phacoemulsification System. 2006-2007

Principal Investigator: Clinical Evaluation of a Modified Light Transmission Tecnis Acrylic Intraocular Lens, 2007 - 2009

Principal Investigator: Clinical Evaluation of a New Viscoelastic for Cataract Surgery, 2009-2010

Coauthors

Research Interests

Blindness; Cataract; Glaucoma, Open-Angle; Glaucoma, Angle-Closure; Diseases; Health Care

Public Health Interests

Bioethics; Chronic Diseases; Global Health; Health Care Management; Infectious Diseases

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Selected Publications