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Arnar Geirsson

MD, FACS, FAHA
Professor of Surgery (Cardiac); Division Chief, Cardiac Surgery, Surgery

Contact Information

Arnar Geirsson, MD, FACS, FAHA

Mailing Address

  • Cardiac Surgery

    PO Box 208062

    New Haven, CT 06520-8062

    United States

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Yale Medicine

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Research Summary

Clinical research projects as part of the Cardiac Surgery Outcome Research Group

1. Volume outcome relationship in cardiac surgery

2. Surgical treatment of endocarditis in drug users

3. Long-term outcomes of patients with severe aortic stenosis - longitudinal data

4. Long-term outcome of patients with severe mitral regurgitation - longitudinal data.

5. Anticoagulation strategies following biological valve replacements.

6. NORCAAD. Nordic Consortium on Acute Type A Aortic Dissection.


Basic science research

1. Pathophysiology of mitral valve prolapse/myxomatous mitral valve disease. Translational research using murine models of mitral valve disease and human mitral valves.


Coauthors

Research Interests

Cardiac Surgical Procedures; Mitral Valve Prolapse; Aortic Aneurysm, Thoracic; Minimally Invasive Surgical Procedures

Research Image

Whole mount IF of anterior leaflet of the mitral valve

PDGFR alpha-GPF mice demonstrating high expression levels in the mitral valve

Selected Publications

  • Clinical implications of Type 2 diabetes on outcomes after cardiac transplantationChouairi F, Mullan C, Ahmed A, Bhinder J, Guha A, Miller P, Jastreboff A, Fuery M, Chiravuri M, Geirsson A, Desai N, Maulion C, Sen S, Ahmad T, Anwer M. Clinical implications of Type 2 diabetes on outcomes after cardiac transplantation PLOS ONE 2022, 17: e0273111. PMID: 36516178, PMCID: PMC9750001, DOI: 10.1371/journal.pone.0273111.
  • Impact of national holidays and weekends on incidence of acute type A aortic dissection repairOudin A, Bjursten H, Oudin Åström D, Nozohoor S, Ahmad K, Tang M, Bjurbom M, Hansson E, Jeppsson A, Moeller C, Jormalainen M, Juvonen T, Mennander A, Olsen P, Olsson C, Ahlsson A, Pan E, Raivio P, Wickbom A, Sjögren J, Geirsson A, Gudbjartsson T, Zindovic I. Impact of national holidays and weekends on incidence of acute type A aortic dissection repair Scientific Reports 2022, 12: 20552. PMID: 36446905, PMCID: PMC9708832, DOI: 10.1038/s41598-022-25076-7.
  • Direct relationship between transvalvular velocity and cardiac dysfunction, morbidity, and mortality in patients with aortic stenosisYousef S, Amabile A, Ram C, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Krane M, Geirsson A, Vallabhajosyula P. Direct relationship between transvalvular velocity and cardiac dysfunction, morbidity, and mortality in patients with aortic stenosis Journal Of Cardiac Surgery 2022, 37: 5052-5062. PMID: 36378856, DOI: 10.1111/jocs.17199.
  • Redo mitral valve surgery: A totally endoscopic, robotic-assisted approach for adhesiolysis and complex repair.Amabile A, LaLonde M, Hameed I, Mullan C, Degife E, Morrison A, Shang M, Komlo C, Krane M, Geirsson A. Redo mitral valve surgery: A totally endoscopic, robotic-assisted approach for adhesiolysis and complex repair. Multimedia Manual Of Cardio-Thoracic Surgery 2022, 2022 PMID: 36367136, DOI: 10.1510/mmcts.2022.061.
  • Temperature effects on incidence of surgery for acute type A aortic dissection in the NordicsÅström D, Bjursten H, Oudin A, Nozohoor S, Ahmad K, Tang M, Bjurbom M, Hansson E, Jeppsson A, Møller C, Jormalainen M, Juvonen T, Mennander A, Olsen P, Olsson C, Ahlsson A, Pan E, Raivio P, Wickbom A, Sjögren J, Geirsson A, Gudbjartsson T, Zindovic I. Temperature effects on incidence of surgery for acute type A aortic dissection in the Nordics Global Health Action 2022, 15: 2139340. PMID: 36345977, PMCID: PMC9648372, DOI: 10.1080/16549716.2022.2139340.
  • John H. Gibbon and the development of the heart‐lung machine: The beginnings of open cardiac surgeryLena T, Amabile A, Morrison A, Torregrossa G, Geirsson A, Tesler UF. John H. Gibbon and the development of the heart‐lung machine: The beginnings of open cardiac surgery Journal Of Cardiac Surgery 2022, 37: 4199-4201. PMID: 36321696, DOI: 10.1111/jocs.17067.
  • Totally endoscopic, robotic-assisted tricuspid valve repair with neochords.Amabile A, LaLonde MR, Mullan CW, Hameed I, Degife E, Krane M, Geirsson A, Agrawal A. Totally endoscopic, robotic-assisted tricuspid valve repair with neochords. Multimedia Manual Of Cardio-Thoracic Surgery 2022, 2022 PMID: 36314718, DOI: 10.1510/mmcts.2022.056.
  • Double Papillary Muscle Relocation: A Totally Endoscopic, Robotic-Assisted Approach.Amabile A, LaLonde MR, Komlo CMK, Mullan CW, Shang M, Agrawal A, Geirsson A, Krane M. Double Papillary Muscle Relocation: A Totally Endoscopic, Robotic-Assisted Approach. Multimedia Manual Of Cardio-Thoracic Surgery 2022, 2022 PMID: 36314585, DOI: 10.1510/mmcts.2022.058.
  • Survival After Heart Transplantation From SARS-CoV-2–Positive DonorsMullan CW, Komlo C, Clark KAA, Sen S, Anwer M, Geirsson A, Ahmad T, Davis RP. Survival After Heart Transplantation From SARS-CoV-2–Positive Donors JACC Heart Failure 2022, 10: 874-876. PMID: 36328657, PMCID: PMC9555312, DOI: 10.1016/j.jchf.2022.08.006.
  • Midterm outcomes of mitral valve repair versus replacement in elderly patients: A propensity score‐matched analysisMuncan B, Amabile A, Kalogeropoulos AP, Geirsson A, Krane M. Midterm outcomes of mitral valve repair versus replacement in elderly patients: A propensity score‐matched analysis Journal Of Cardiac Surgery 2022, 37: 4391-4396. PMID: 36168792, DOI: 10.1111/jocs.16972.
  • Risk factors and mortality associated with permanent pacemaker after surgical or transcatheter aortic valve replacement: Early versus late implantationBin Mahmood SU, Mori M, Amabile A, Prescher L, Forrest J, Kaple R, Geirsson A, Mangi AA. Risk factors and mortality associated with permanent pacemaker after surgical or transcatheter aortic valve replacement: Early versus late implantation Journal Of Cardiac Surgery 2022, 37: 4295-4300. PMID: 36131523, DOI: 10.1111/jocs.16938.
  • A Modified Approach for Totally Endoscopic, Touchless Radial Artery HarvestingLaLonde M, Amabile A, Bialecki J, Larson H, Krane M, Geirsson A, Williams M. A Modified Approach for Totally Endoscopic, Touchless Radial Artery Harvesting JTCVS Techniques 2022, 16: 89-91. PMID: 36510509, PMCID: PMC9735387, DOI: 10.1016/j.xjtc.2022.09.008.
  • Two hundred robotic mitral valve repair procedures for degenerative mitral regurgitation: the Yale experienceAmabile A, Morrison A, LaLonde M, Agarwal R, Mori M, Hameed I, Bin Mahmood SU, Komlo C, Ragnarsson S, Krane M, Geirsson A. Two hundred robotic mitral valve repair procedures for degenerative mitral regurgitation: the Yale experience Annals Of Cardiothoracic Surgery 2022, 0: 0-0. PMID: 36237593, PMCID: PMC9551370, DOI: 10.21037/acs-2022-rmvs-73.
  • Long‐term risk of arch complications in Loeys Dietz syndrome patients undergoing proximal ascending aortic replacementWeininger G, Zafar M, Ziganshin BA, Mori M, Papanikolaou D, Sekar RB, Amabile A, Degife E, O'Marr J, Geirsson A, Elefteriades JA, Assi R, Vallabhajosyula P. Long‐term risk of arch complications in Loeys Dietz syndrome patients undergoing proximal ascending aortic replacement Journal Of Cardiac Surgery 2022, 37: 3688-3692. PMID: 35989525, DOI: 10.1111/jocs.16855.
  • Commentary: Dysregulated Coronary Tone in Uncontrolled Hypertension; Why it Matters for the Cardiac SurgeonSotolongo A, Geirsson A. Commentary: Dysregulated Coronary Tone in Uncontrolled Hypertension; Why it Matters for the Cardiac Surgeon Journal Of Thoracic And Cardiovascular Surgery 2022 PMID: 36038383, DOI: 10.1016/j.jtcvs.2022.08.002.
  • Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathyMori M, Mark DB, Khera R, Lin H, Jones P, Huang C, Lu Y, Geirsson A, Velazquez EJ, Spertus JA, Krumholz HM. Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathy American Heart Journal 2022, 254: 12-22. PMID: 35932911, DOI: 10.1016/j.ahj.2022.07.007.
  • Screening Tool to Identify Patients with Advanced Aortic Valve StenosisYousef S, Amabile A, Ram C, Huang H, Korutla V, Singh S, Agarwal R, Assi R, Milewski RK, Zhang Y, Patel PA, Krane M, Geirsson A, Vallabhajosyula P. Screening Tool to Identify Patients with Advanced Aortic Valve Stenosis Journal Of Clinical Medicine 2022, 11: 4386. PMID: 35956007, PMCID: PMC9369431, DOI: 10.3390/jcm11154386.
  • Early Surgery for Patients With Asymptomatic Severe Aortic Stenosis: A Meta-Analysis of Randomized Controlled TrialsAhmad Y, Howard J, Seligman H, Arnold A, Madhavan M, Forrest J, Geirsson A, Mack M, Lansky A, Leon M. Early Surgery for Patients With Asymptomatic Severe Aortic Stenosis: A Meta-Analysis of Randomized Controlled Trials Journal Of The Society For Cardiovascular Angiography & Interventions 2022, 1: 100383. DOI: 10.1016/j.jscai.2022.100383.
  • Pioneers in congenital cardiac surgery: Dr. William Imon Norwood, Jr, MD, PhDLee ME, Kopf GS, Geirsson A, Gruber PJ. Pioneers in congenital cardiac surgery: Dr. William Imon Norwood, Jr, MD, PhD Journal Of Cardiac Surgery 2022, 37: 2521-2523. PMID: 35748274, DOI: 10.1111/jocs.16694.
  • Type-A Aortic Dissection Repair in Patients With Prior Cardiac SurgeryBjurbom M, Olsson C, Geirsson A, Gudbjartsson T, Gunn J, Hansson EC, Hjortdal V, Jeppsson A, Mennander A, Ede J, Zindovic I, Ahlsson A, Wickbom A, Dalén M. Type-A Aortic Dissection Repair in Patients With Prior Cardiac Surgery The Annals Of Thoracic Surgery 2022 PMID: 35688205, DOI: 10.1016/j.athoracsur.2022.05.033.
  • One and Five-Year Mortality Risk Prediction in Patients with Moderate and Severe Aortic StenosisYousef S, Amabile A, Huang H, Agarwal R, Singh S, Ram C, Milewski RK, Assi R, Zhang Y, Krane M, Geirsson A, Vallabhajosyula P. One and Five-Year Mortality Risk Prediction in Patients with Moderate and Severe Aortic Stenosis Journal Of Clinical Medicine 2022, 11: 2949. PMID: 35629075, PMCID: PMC9146915, DOI: 10.3390/jcm11102949.
  • Expanding Heart Transplants from Donors After Circulatory Death (DCD) - Results of the First Randomized Controlled Trial Using the Organ Care System (OCS™) Heart - (OCS DCD Heart Trial)Schroder J, Shah A, Pretorius V, Smith J, Daneshmand M, Geirsson A, Pham S, Um J, Silvestry S, Shaffer A, Mudy K, Kai M, Joyce D, Philpott J, Takeda K, Goldstein D, Shudo Y, Couper G, Mallidi H, Esmailian F, Pham D, Salerno C, Lozonschi L, Quader M, Patel C, DeVore A, Bryner B, Madsen J, Absi T, Milano C, D'Alessandro D. Expanding Heart Transplants from Donors After Circulatory Death (DCD) - Results of the First Randomized Controlled Trial Using the Organ Care System (OCS™) Heart - (OCS DCD Heart Trial) The Journal Of Heart And Lung Transplantation 2022, 41: s72. DOI: 10.1016/j.healun.2022.01.165.
  • IMPACT OF ATRIAL FIBRILLATION ON SURVIVAL IN PATIENTS WITH DILATED ATRIUM ACROSS DIFFERENT SEVERITIES OF ATRIAL FUNCTIONAL MITRAL REGURGITATIONAmabile A, Mori M, Zogg C, Agarwal R, Krane M, Sugeng L, GEIRSSON A. IMPACT OF ATRIAL FIBRILLATION ON SURVIVAL IN PATIENTS WITH DILATED ATRIUM ACROSS DIFFERENT SEVERITIES OF ATRIAL FUNCTIONAL MITRAL REGURGITATION Journal Of The American College Of Cardiology 2022, 79: 219. DOI: 10.1016/s0735-1097(22)01210-4.
  • Robotic, totally endoscopic excision of mitral valve papillary fibroelastoma.Amabile A, Morrison A, Weininger G, LaLonde M, Krane M, Geirsson A. Robotic, totally endoscopic excision of mitral valve papillary fibroelastoma. Multimedia Manual Of Cardio-Thoracic Surgery 2021, 2021 PMID: 34491636, DOI: 10.1510/mmcts.2021.045.
  • Abstract 12518: Susceptibility of Mature Human Myocardial Cell Types to SARS-CoV-2Sotolongo A, Klein J, Pena-Hernandez M, Johnson J, Geirsson A, Pober J, Iwasaki A, Gruber P. Abstract 12518: Susceptibility of Mature Human Myocardial Cell Types to SARS-CoV-2 Circulation 2021, 144: a12518-a12518. DOI: 10.1161/circ.144.suppl_1.12518.
  • Abstract 12292: Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency CandidatesFuery M, Chouairi F, Natov P, Bhinder J, Chiravuri M, Wilson L, Clark K, Reinhardt S, Mullan C, Miller E, Rogers J, Patel C, Sen S, Geirsson A, Anwer M, Desai N, Ahmad T. Abstract 12292: Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates Circulation 2021, 144: a12292-a12292. DOI: 10.1161/circ.144.suppl_1.12292.
  • CARDIAC STRUCTURAL CHANGES, END-ORGAN MORBIDITIES AND MORTALITY RELATE TO AORTIC STENOSIS IN A DEGREE-REPONSE RELATIONSHIPYousef S, Ram C, Singh S, Agarwal R, Milewski R, Assi R, Geirsson A, Vallabhajosyula P. CARDIAC STRUCTURAL CHANGES, END-ORGAN MORBIDITIES AND MORTALITY RELATE TO AORTIC STENOSIS IN A DEGREE-REPONSE RELATIONSHIP Journal Of The American College Of Cardiology 2021, 77: 1750. DOI: 10.1016/s0735-1097(21)03106-5.
  • ZFYVE21 is a Mediator of Non-Canonical Hedgehog Signaling Activating NLRP3 Inflammasomes in a Pathologic Subset of CD4+PD-1hi T CellsJiang B, Fang C, Soh C, Li X, Geirsson A, Tellides G, Pober J, Jane-Wit D. ZFYVE21 is a Mediator of Non-Canonical Hedgehog Signaling Activating NLRP3 Inflammasomes in a Pathologic Subset of CD4+PD-1hi T Cells The Journal Of Heart And Lung Transplantation 2021, 40: s136. DOI: 10.1016/j.healun.2021.01.422.
  • CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH COVID-19 WITH RESPIRATORY FAILURE REQUIRING EXTRACORPOREAL MEMBRANE OXYGENATIONFouad J, Singh I, Khosla A, Szabo C, Tantawy H, Razo-Vazquez A, Geirsson A, Bonde P, Fajardo E, Joseph P, Siner J, Chichra A. CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH COVID-19 WITH RESPIRATORY FAILURE REQUIRING EXTRACORPOREAL MEMBRANE OXYGENATION CHEST Journal 2020, 158: a703-a704. PMCID: PMC7548617, DOI: 10.1016/j.chest.2020.08.660.
  • SUCCESSFUL ROBOTIC MITRAL VALVE REPAIR OF ENDOCARDITIS WITH LEAFLET PERFORATION IN A HIGH RISK PATIENTJeyashanmugaraja G, Stawiarski K, Gomez D, Geirsson A, Zarich S. SUCCESSFUL ROBOTIC MITRAL VALVE REPAIR OF ENDOCARDITIS WITH LEAFLET PERFORATION IN A HIGH RISK PATIENT CHEST Journal 2020, 158: a163. DOI: 10.1016/j.chest.2020.08.177.
  • TCT CONNECT-107 Poor Survival in Patients With Aortic Stenosis Without InterventionYousef S, Same H, Mori M, Agarwal R, Singh S, Brooks C, Mena-Hurtado C, Smolderen K, Nagpal S, Cleman M, Forrest J, Kaple R, Zhang Y, Assi R, Geirsson A. TCT CONNECT-107 Poor Survival in Patients With Aortic Stenosis Without Intervention Journal Of The American College Of Cardiology 2020, 76: b47-b48. DOI: 10.1016/j.jacc.2020.09.121.
  • TCT CONNECT-4 Surgical EXPLANTation After Transcatheter Aortic Valve Replacement Failure: Midterm Outcomes From the EXPLANT-TAVR International RegistryTang G, Sengupta A, Zaid S, Vitanova K, Lange R, Munsterer A, Simon S, Fukuhara S, Deeb G, Oakley J, Voisine P, Mohammadi S, Kalavrouziotis D, Doyle D, Rodés-Cabau J, Dumont E, Alperi A, von Ballmoos M, Reardon M, Atkins M, Kleiman N, Chu M, Bagur R, Algadheeb M, Desai N, Bavaria J, Walsh E, Conradi L, Bhadra O, Schults C, Satler L, Waksman R, Ramlawi B, Andreas M, Werner P, Modine T, Leroux L, Whisenant B, Doty J, Robinson N, Wang L, Petrossian G, Goldberg J, Spielvogel D, Ahmad H, Bruschi G, Goel K, Shah A, Geirsson A, Forrest J, Grubb K, Hirji S, Shah P, Gelpi G, Ouzounian M, Ruel M, Al-Atassi T, Kempfert J, Unbehaun A, Sonnabend S, Ali W, Demers P, Ibrahim R, Garatti A, Nguyen T, Pizano A, Di Eusanio M, Capestro F, Estevez-Loureiro R, Salinger M, Rovin J, Fisher S, D'Onofrio A, Divirgilio A, Maisano F, Taramasso M, Gennari M, Colli A, Denti P, Kaneko T, Bapat V. TCT CONNECT-4 Surgical EXPLANTation After Transcatheter Aortic Valve Replacement Failure: Midterm Outcomes From the EXPLANT-TAVR International Registry Journal Of The American College Of Cardiology 2020, 76: b2-b3. DOI: 10.1016/j.jacc.2020.09.019.
  • TCT CONNECT-112 Intervention Management Strategies and Association With Long-Term Mortality in Patients With Concomitant Aortic Valve Stenosis and Coronary Artery DiseaseYousef S, Mori M, Assi R, Smolderen K, Kaple R, Forrest J, Cleman M, Mena-Hurtado C, Geirsson A, Vallabhajosyula P. TCT CONNECT-112 Intervention Management Strategies and Association With Long-Term Mortality in Patients With Concomitant Aortic Valve Stenosis and Coronary Artery Disease Journal Of The American College Of Cardiology 2020, 76: b50. DOI: 10.1016/j.jacc.2020.09.126.
  • Cardiac surgery in North America and coronavirus disease 2019 (COVID-19): Regional variability in burden and impactAd N, Luc J, Nguyen T, Arora R, Balkhy H, Bender E, Bethencourt D, Bisleri G, Boyd D, Chu M, de la Cruz K, DeAnda A, Engelman D, Farkas E, Fedoruk L, Fiocco M, Forcillo J, Fradet G, Fremes S, Gammie J, Geirsson A, Gerdisch M, Girardi L, Kaiser C, Kaneko T, Kent W, Khabbaz K, Khoynezhad A, Kiaii B, Lee R, Legare J, Lehr E, MacArthur R, McCarthy P, Mehall J, Merrill W, Moon M, Ouzounian M, Peltz M, Perrault L, Preventza O, Ramchandani M, Ramlawi B, Salenger R, Sekela M, Sellke F, Stulak J, Sutter F, Timek T, Whitman G, Williams J, Wong D, Yanagawa B, Ye J, Zeigler S, . Cardiac surgery in North America and coronavirus disease 2019 (COVID-19): Regional variability in burden and impact Journal Of Thoracic And Cardiovascular Surgery 2020, 162: 893-903.e4. PMID: 32768300, PMCID: PMC7330597, DOI: 10.1016/j.jtcvs.2020.06.077.
  • The Evolving Burden of Drug Use Associated Infective Endocarditis in the United StatesGeirsson A, Schranz A, Jawitz O, Mori M, Feng L, Zwischenberger BA, Iribarne A, Dearani J, Rushing G, Badhwar V, Crestanello JA. The Evolving Burden of Drug Use Associated Infective Endocarditis in the United States The Annals Of Thoracic Surgery 2020, 110: 1185-1192. PMID: 32387035, PMCID: PMC7502470, DOI: 10.1016/j.athoracsur.2020.03.089.
  • Abstract 215: Cardiac Surgeons' Treatment Preferences for Infective Endocarditis Based on Patients' Drug Use StatusNguemeni Tiako M, Mori M, Bin Mahmood S, Mszar R, Brooks C, Bonde P, Tellides G, Weimer M, Geirsson A. Abstract 215: Cardiac Surgeons' Treatment Preferences for Infective Endocarditis Based on Patients' Drug Use Status Circulation Cardiovascular Quality And Outcomes 2020, 13 DOI: 10.1161/hcq.13.suppl_1.215.
  • Outcomes of Left Ventricular Assist Device Implantation with Mitral Regurgitation with and without Concomitant Mitral OperationVinholo T, Mullan C, Mori M, Caraballo C, Ravindra N, Miller E, McCullough M, Clarke J, Geirsson A, Desai N, Ahmad T. Outcomes of Left Ventricular Assist Device Implantation with Mitral Regurgitation with and without Concomitant Mitral Operation The Journal Of Heart And Lung Transplantation 2020, 39: s441-s442. DOI: 10.1016/j.healun.2020.01.251.
  • Clinical Implications of Concomitant Surgical Intervention for Aortic Insufficiency with Left Ventricular Assist Device ImplantationMullan C, Mori M, Caraballo C, Ravindra N, Miller E, McCullough M, Clarke J, Geirsson A, Desai N, Ahmad T. Clinical Implications of Concomitant Surgical Intervention for Aortic Insufficiency with Left Ventricular Assist Device Implantation The Journal Of Heart And Lung Transplantation 2020, 39: s440. DOI: 10.1016/j.healun.2020.01.248.
  • Blood Conservation Strategy at Time of Left Ventricular Assist Device Placement Improves SurvivalStawiarski K, Agboola O, Park J, Mangi A, Geirsson A, Lee F, Jacoby D, Bellumkonda L, Ahmad T, Chou J, Testani J, Chen M, McCloskey G, Bonde P. Blood Conservation Strategy at Time of Left Ventricular Assist Device Placement Improves Survival The Journal Of Heart And Lung Transplantation 2020, 39: s151. DOI: 10.1016/j.healun.2020.01.1086.
  • Questionable Value of Concomitant Tricuspid Valve Procedure with Left Ventricular Assist Device ImplantationMullan C, Mori M, Caraballo C, Ravindra N, Miller E, McCullough M, Clarke J, Geirsson A, Desai N, Ahmad T. Questionable Value of Concomitant Tricuspid Valve Procedure with Left Ventricular Assist Device Implantation The Journal Of Heart And Lung Transplantation 2020, 39: s118. DOI: 10.1016/j.healun.2020.01.997.
  • The Effects of Less Invasive Extra-Pericardial Placement of Left Ventricular Assist Devices on Right Ventricular Failure in the Early Postoperative PeriodStawiarski K, Agboola O, Park J, Mangi A, Geirsson A, Bellumkonda L, Lee F, Chen M, Jacoby D, Chou J, Ahmad T, Testani J, McCloskey G, Bonde P. The Effects of Less Invasive Extra-Pericardial Placement of Left Ventricular Assist Devices on Right Ventricular Failure in the Early Postoperative Period The Journal Of Heart And Lung Transplantation 2020, 39: s151-s152. DOI: 10.1016/j.healun.2020.01.1087.
  • Diabetes and Hypertension Associate Differently With the Risk of Ascending Thoracic Aortic Aneurysm A CT Study of 21,295 PatientsMori M, Yousef S, Zhuo H, Bin Mahmood SU, Mojibian H, Zhang Y, Geirsson A. Diabetes and Hypertension Associate Differently With the Risk of Ascending Thoracic Aortic Aneurysm A CT Study of 21,295 Patients JACC Cardiovascular Imaging 2020, 13: 1634-1636. PMID: 32199842, DOI: 10.1016/j.jcmg.2020.02.004.
  • Trends in Infective Endocarditis Hospitalizations, Characteristics, and Valve Operations in Patients With Opioid Use Disorders in the United States: 2005–2014Mori M, Brown KJ, Bin Mahmood SU, Geirsson A, Mangi AA. Trends in Infective Endocarditis Hospitalizations, Characteristics, and Valve Operations in Patients With Opioid Use Disorders in the United States: 2005–2014 Journal Of The American Heart Association 2020, 9: e012465. PMID: 32172645, PMCID: PMC7335511, DOI: 10.1161/jaha.119.012465.
  • REAL-WORLD VERSUS CLINICAL TRIAL OUTCOMES FROM LVADSMezzacappa C, Ravindra N, Carabello C, Chouairi F, McCullough M, Miller P, Clarke J, Gruen J, Mullan C, Geirsson A, Rogers J, Desai N, Ahmad T. REAL-WORLD VERSUS CLINICAL TRIAL OUTCOMES FROM LVADS Journal Of The American College Of Cardiology 2020, 75: 771. DOI: 10.1016/s0735-1097(20)31398-x.
  • CLINICAL IMPACT OF PSYCHIATRIC COMORBIDITIES ON OUTCOMES AFTER LEFT VENTRICULAR ASSIST DEVICE IMPLANTATIONMullan C, Mori M, Caraballo C, Ravindra N, Miller P, McCullough M, Clarke J, Geirsson A, Desai N, Ahmad T. CLINICAL IMPACT OF PSYCHIATRIC COMORBIDITIES ON OUTCOMES AFTER LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION Journal Of The American College Of Cardiology 2020, 75: 967. DOI: 10.1016/s0735-1097(20)31594-1.
  • Surgeons: Buyer beware—does “universal” risk prediction model apply to patients universally?Mori M, Shahian DM, Huang C, Li SX, Normand ST, Geirsson A, Krumholz HM. Surgeons: Buyer beware—does “universal” risk prediction model apply to patients universally? Journal Of Thoracic And Cardiovascular Surgery 2020, 160: 176-179.e2. PMID: 32241616, DOI: 10.1016/j.jtcvs.2019.11.144.
  • Chronic mTOR activation induces a degradative smooth muscle cell phenotypeLi G, Wang M, Caulk AW, Cilfone NA, Gujja S, Qin L, Chen PY, Chen Z, Yousef S, Jiao Y, He C, Jiang B, Korneva A, Bersi MR, Wang G, Liu X, Mehta S, Geirsson A, Gulcher JR, Chittenden TW, Simons M, Humphrey JD, Tellides G. Chronic mTOR activation induces a degradative smooth muscle cell phenotype Journal Of Clinical Investigation 2020, 130: 1233-1251. PMID: 32039915, PMCID: PMC7269581, DOI: 10.1172/jci131048.
  • P206 Immediate impact of coronary revascularization on global and regional myocardial function evaluated by speckle tracking echocardiographyChen W, Zhu Q, Posada-Martinez E, Ortiz-Leon X, Pereira J, Dewar M, Darr U, Geirsson A, Sugeng L. P206 Immediate impact of coronary revascularization on global and regional myocardial function evaluated by speckle tracking echocardiography European Heart Journal - Cardiovascular Imaging 2020, 21 DOI: 10.1093/ehjci/jez319.074.
  • TCT-763 Valve in Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement: Real World Outcomes From the National Inpatient Sample (2013–2016)Kim G, Geirsson A, Cleman M, Forrest J, Kaple R. TCT-763 Valve in Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement: Real World Outcomes From the National Inpatient Sample (2013–2016) Journal Of The American College Of Cardiology 2019, 74: b748. DOI: 10.1016/j.jacc.2019.08.902.
  • TCT-237 Revascularization Options for Women With Coronary Artery Disease: A Meta-Analysis of Randomized Controlled TrialsShah T, Gul B, Head S, Abbott J, Chieffo A, Baumbach A, Hu X, Li F, Brackett A, Gesick C, Bisarya P, Mehran R, Grines C, Geirsson A, Mehilli J, Lansky A. TCT-237 Revascularization Options for Women With Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials Journal Of The American College Of Cardiology 2019, 74: b236. DOI: 10.1016/j.jacc.2019.08.303.
  • Risk of reoperative valve surgery for endocarditis associated with drug useMori M, Bin Mahmood SU, Schranz AJ, Sultan I, Axtell AL, Sarsour N, Hiesinger W, Boskovski MT, Hirji S, Kaneko T, Woo J, Tang P, Jassar AS, Atluri P, Whitson BA, Gleason T, Geirsson A. Risk of reoperative valve surgery for endocarditis associated with drug use Journal Of Thoracic And Cardiovascular Surgery 2019, 159: 1262-1268.e2. PMID: 31420136, PMCID: PMC6952585, DOI: 10.1016/j.jtcvs.2019.06.055.
  • Abstract 255: Patterns of Addiction Treatment for Patients Undergoing Cardiac Surgery for Infective Endocarditis Associated with Intravenous Drug UseNguemeni Tiako M, Hong S, Bin Mahmood S, Darr U, Mangi A, Jutthani-Mehta M, Geirsson A. Abstract 255: Patterns of Addiction Treatment for Patients Undergoing Cardiac Surgery for Infective Endocarditis Associated with Intravenous Drug Use Circulation Cardiovascular Quality And Outcomes 2019, 12 DOI: 10.1161/hcq.12.suppl_1.255.
  • LVAD Survival May Be Predicted by Preoperative LymphopeniaStawiarski K, Agboola O, Jacoby D, Bellumkonda L, Sugeng L, Ahmad T, Chen M, McCloskey G, Geirsson A, Anwar M, Bonde P. LVAD Survival May Be Predicted by Preoperative Lymphopenia The Journal Of Heart And Lung Transplantation 2019, 38: s63-s64. DOI: 10.1016/j.healun.2019.01.142.
  • Chloride Homeostasis in End Stage Heart Failure and LVAD RecipientsStawiarski K, Agboola O, Jacoby D, Bellumkonda L, Ahmad T, Sugeng L, Chen M, McCloskey G, Geirsson A, Anwar M, Bonde P. Chloride Homeostasis in End Stage Heart Failure and LVAD Recipients The Journal Of Heart And Lung Transplantation 2019, 38: s382-s383. DOI: 10.1016/j.healun.2019.01.974.
  • IDENTIFICATION OF RISK FACTORS AND DEVELOPMENT AND VALIDATION OF A PREDICTION MODEL TO DETECT ASCENDING THORACIC AORTIC ANEURYSMMori M, Yousef S, Bin Mahmood S, Mangi A, Geirsson A. IDENTIFICATION OF RISK FACTORS AND DEVELOPMENT AND VALIDATION OF A PREDICTION MODEL TO DETECT ASCENDING THORACIC AORTIC ANEURYSM Journal Of The American College Of Cardiology 2019, 73: 1558. DOI: 10.1016/s0735-1097(19)32164-3.
  • TRENDS IN INFECTIVE ENDOCARDITIS INCIDENCE, CHARACTERISTICS, AND VALVE REPLACEMENT IN PATIENTS WITH OPIOID USE DISORDERS IN THE UNITED STATES FROM 2005 TO 2014Mori M, Brown K, Bin Mahmood S, Geirsson A, Mangi A. TRENDS IN INFECTIVE ENDOCARDITIS INCIDENCE, CHARACTERISTICS, AND VALVE REPLACEMENT IN PATIENTS WITH OPIOID USE DISORDERS IN THE UNITED STATES FROM 2005 TO 2014 Journal Of The American College Of Cardiology 2019, 73: 1968. DOI: 10.1016/s0735-1097(19)32574-4.
  • LYMPHOPENIA AS A PREDICTOR FOR SURVIVAL IN LVAD PATIENTSStawiarski K, Agboola O, Jacoby D, Ali A, Bellumkonda L, Ahmad T, Sugeng L, McCloskey G, Chen M, Geirsson A, Bonde P, Anwer M. LYMPHOPENIA AS A PREDICTOR FOR SURVIVAL IN LVAD PATIENTS Journal Of The American College Of Cardiology 2019, 73: 802. DOI: 10.1016/s0735-1097(19)31409-3.
  • TCF7L2 (Transcription Factor 7-Like 2) Regulation of GATA6 (GATA-Binding Protein 6)-Dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal HyperplasiaSrivastava R, Rolyan H, Xie Y, Li N, Bhat N, Hong L, Esteghamat F, Adeniran A, Geirsson A, Zhang J, Ge G, Nobrega M, Martin KA, Mani A. TCF7L2 (Transcription Factor 7-Like 2) Regulation of GATA6 (GATA-Binding Protein 6)-Dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia Arteriosclerosis Thrombosis And Vascular Biology 2018, 39: 250-262. PMID: 30567484, PMCID: PMC6365015, DOI: 10.1161/atvbaha.118.311830.
  • Differential outcomes of open and clamp-on distal anastomosis techniques in acute type A aortic dissectionGeirsson A, Shioda K, Olsson C, Ahlsson A, Gunn J, Hansson EC, Hjortdal V, Jeppsson A, Mennander A, Wickbom A, Zindovic I, Gudbjartsson T. Differential outcomes of open and clamp-on distal anastomosis techniques in acute type A aortic dissection Journal Of Thoracic And Cardiovascular Surgery 2018, 157: 1750-1758. PMID: 30401530, DOI: 10.1016/j.jtcvs.2018.09.020.
  • Árangur kransæðahjáveituaðgerða hjá konum á ÍslandiGarðarsdóttir H, Árnadóttir L, Aðalsteinsson J, Jóhannesdóttir H, Helgadóttir S, Hrafnkelsdóttir Þ, Geirsson A, Guðbjartsson T. Árangur kransæðahjáveituaðgerða hjá konum á Íslandi Læknablaðið 2018, 2018: 335-340. DOI: 10.17992/lbl.2018.0708.192.
  • Perioperative Risk Profiles and Volume-Outcome Relationships in Proximal Thoracic Aortic SurgeryMori M, Shioda K, Wang X, Mangi AA, Yun JJ, Darr U, Elefteriades JA, Geirsson A. Perioperative Risk Profiles and Volume-Outcome Relationships in Proximal Thoracic Aortic Surgery The Annals Of Thoracic Surgery 2018, 106: 1095-1104. PMID: 29969620, DOI: 10.1016/j.athoracsur.2018.05.081.
  • Comparable perioperative outcomes and mid-term survival in prosthetic valve endocarditis and native valve endocarditis.Mori M, Shioda K, Nguemeni Tiako MJ, Bin Mahmood SU, Mangi AA, Yun JJ, Darr U, Pang PYK, Geirsson A. Comparable perioperative outcomes and mid-term survival in prosthetic valve endocarditis and native valve endocarditis. European Journal Of Cardio-Thoracic Surgery 2018, 54: 1067-1072. PMID: 29726931, DOI: 10.1093/ejcts/ezy191.
  • Hospital volumes and later year of operation correlates with better outcomes in acute Type A aortic dissectionGeirsson A, Ahlsson A, Franco-Cereceda A, Fuglsang S, Gunn J, Hansson EC, Hjortdal V, Jarvela K, Jeppsson A, Mennander A, Nozohoor S, Olsson C, Pan E, Wickbom A, Zindovic I, Gudbjartsson T. Hospital volumes and later year of operation correlates with better outcomes in acute Type A aortic dissection European Journal Of Cardio-Thoracic Surgery 2017, 53: 276-281. PMID: 28977415, DOI: 10.1093/ejcts/ezx231.
  • The incidence and mortality of acute thoracic aortic dissection: results from a whole nation studyMelvinsdottir IH, Lund SH, Agnarsson BA, Sigvaldason K, Gudbjartsson T, Geirsson A. The incidence and mortality of acute thoracic aortic dissection: results from a whole nation study European Journal Of Cardio-Thoracic Surgery 2016, 50: 1111-1117. PMID: 27334108, DOI: 10.1093/ejcts/ezw235.
  • Abstract 17817: The Incidence and Mortality Risk of Acute Thoracic Aortic Dissection: Results From a Nationwide Population-based StudyMelvinsdottir I, Lund S, Agnarsson B, Sigvaldason K, Gudbjartsson T, Geirsson A. Abstract 17817: The Incidence and Mortality Risk of Acute Thoracic Aortic Dissection: Results From a Nationwide Population-based Study Circulation 2015, 132 DOI: 10.1161/circ.132.suppl_3.17817.
  • Urine Biomarkers and Perioperative Acute Kidney Injury: The Impact of Preoperative Estimated GFRKoyner JL, Coca SG, Thiessen-Philbrook H, Patel UD, Shlipak MG, Garg AX, Parikh CR, Consortium T, Raman J, Jeevanandam V, Akhter S, Devarajan P, Bennett M, Ma Q, Griffiths R, Edelstein C, Passik C, Nagy J, Swaminathan M, Chu M, Goldbach M, Guo L, McKenzie N, Myers M, Novick R, Quantz M, Schumann V, Webster L, Zappitelli M, Palijan A, Dewar M, Darr U, Hashim S, Elefteriades J, Geirsson A, Garwood S, Kemp R, Butrymowicz I. Urine Biomarkers and Perioperative Acute Kidney Injury: The Impact of Preoperative Estimated GFR American Journal Of Kidney Diseases 2015, 66: 1006-1014. PMID: 26386737, PMCID: PMC4658239, DOI: 10.1053/j.ajkd.2015.07.027.
  • Trends in Aortic Dissection Hospitalizations, Interventions, and Outcomes Among Medicare Beneficiaries in the United States, 2000–2011Mody PS, Wang Y, Geirsson A, Kim N, Desai MM, Gupta A, Dodson JA, Krumholz HM. Trends in Aortic Dissection Hospitalizations, Interventions, and Outcomes Among Medicare Beneficiaries in the United States, 2000–2011 Circulation Cardiovascular Quality And Outcomes 2014, 7: 920-928. PMID: 25336626, PMCID: PMC4380171, DOI: 10.1161/circoutcomes.114.001140.
  • The “Free” Right Internal Thoracic Artery: A Versatile and Durable ConduitAssi R, Youssef SJ, Almarzooq Z, Al‐Raweshidy Y, Hashim PW, Geirsson A, Hashim SW. The “Free” Right Internal Thoracic Artery: A Versatile and Durable Conduit Journal Of Cardiac Surgery 2014, 29: 609-615. PMID: 25040250, DOI: 10.1111/jocs.12396.
  • Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasisLi W, Li Q, Jiao Y, Qin L, Ali R, Zhou J, Ferruzzi J, Kim RW, Geirsson A, Dietz HC, Offermanns S, Humphrey JD, Tellides G. Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis Journal Of Clinical Investigation 2014, 124: 755-767. PMID: 24401272, PMCID: PMC3904608, DOI: 10.1172/jci69942.
  • Trends in Aortic Valve Replacement for Elderly Patients in the United States, 1999-2011Barreto-Filho JA, Wang Y, Dodson JA, Desai MM, Sugeng L, Geirsson A, Krumholz HM. Trends in Aortic Valve Replacement for Elderly Patients in the United States, 1999-2011 JAMA 2013, 310: 2078-2084. PMID: 24240935, PMCID: PMC4089974, DOI: 10.1001/jama.2013.282437.
  • Preoperative angiotensin-converting enzyme inhibitors and angiotensin receptor blocker use and acute kidney injury in patients undergoing cardiac surgeryCoca SG, Garg AX, Swaminathan M, Garwood S, Hong K, Thiessen-Philbrook H, Passik C, Koyner JL, Parikh CR, Jai R, Jeevanandam V, Akhter S, Devarajan P, Bennett M, Edelsteinm C, Patel U, Chu M, Goldbach M, Guo L, McKenzie N, Myers M, Novick R, Quantz M, Zappitelli M, Dewar M, Darr U, Hashim S, Elefteriades J, Geirsson A. Preoperative angiotensin-converting enzyme inhibitors and angiotensin receptor blocker use and acute kidney injury in patients undergoing cardiac surgery Nephrology Dialysis Transplantation 2013, 28: 2787-2799. PMID: 24081864, PMCID: PMC3811062, DOI: 10.1093/ndt/gft405.
  • Modulation of Transforming Growth Factor-&bgr; Signaling and Extracellular Matrix Production in Myxomatous Mitral Valves by Angiotensin II Receptor BlockersGeirsson A, Singh M, Ali R, Abbas H, Li W, Sanchez JA, Hashim S, Tellides G. Modulation of Transforming Growth Factor-&bgr; Signaling and Extracellular Matrix Production in Myxomatous Mitral Valves by Angiotensin II Receptor Blockers Circulation 2012, 126: s189-s197. PMID: 22965982, DOI: 10.1161/circulationaha.111.082610.
  • miR-1 mediated suppression of Sorcin regulates myocardial contractility through modulation of Ca2+ signalingAli R, Huang Y, Maher SE, Kim RW, Giordano FJ, Tellides G, Geirsson A. miR-1 mediated suppression of Sorcin regulates myocardial contractility through modulation of Ca2+ signaling Journal Of Molecular And Cellular Cardiology 2012, 52: 1027-1037. PMID: 22326846, DOI: 10.1016/j.yjmcc.2012.01.020.
  • Pseudoprolapse of the anterior leaflet in chronic ischemic mitral regurgitation: Identification and repairHashim SW, Youssef SJ, Ayyash B, Rousou AJ, Ragnarsson S, Collazo S, Geirsson A. Pseudoprolapse of the anterior leaflet in chronic ischemic mitral regurgitation: Identification and repair Journal Of Thoracic And Cardiovascular Surgery 2011, 143: s33-s37. PMID: 22050989, DOI: 10.1016/j.jtcvs.2011.09.063.
  • Circulating interferon-γ–inducible Cys-X-Cys chemokine receptor 3 ligands are elevated in humans with aortic aneurysms and Cys-X-Cys chemokine receptor 3 is necessary for aneurysm formation in miceGallo A, Saad A, Ali R, Dardik A, Tellides G, Geirsson A. Circulating interferon-γ–inducible Cys-X-Cys chemokine receptor 3 ligands are elevated in humans with aortic aneurysms and Cys-X-Cys chemokine receptor 3 is necessary for aneurysm formation in mice Journal Of Thoracic And Cardiovascular Surgery 2011, 143: 704-710. PMID: 21962843, PMCID: PMC4526250, DOI: 10.1016/j.jtcvs.2011.08.036.
  • Activation of human vascular cells decreases their expression of transforming growth factor-betaLebastchi AH, Qin L, Khan SF, Zhou J, Geirsson A, Kim RW, Li W, Tellides G. Activation of human vascular cells decreases their expression of transforming growth factor-beta Atherosclerosis 2011, 219: 417-424. PMID: 21862019, PMCID: PMC3226933, DOI: 10.1016/j.atherosclerosis.2011.07.121.
  • Surgical Treatment of Thoracic Aortic Disease in the ElderlyGeirsson A. Surgical Treatment of Thoracic Aortic Disease in the Elderly 2011, 427-436. DOI: 10.1007/978-1-4419-0892-6_33.
  • Oesophageal Perforations in Iceland: a Whole Population Study on Incidence, Aetiology and Surgical OutcomeVidarsdottir1 H, Blondal1 S, Alfredsson2 H, Geirsson3 A, Gudbjartsson2 T. Oesophageal Perforations in Iceland: a Whole Population Study on Incidence, Aetiology and Surgical Outcome The Thoracic And Cardiovascular Surgeon 2010, 58: 476-480. PMID: 21110271, DOI: 10.1055/s-0030-1250347.
  • IFN-γ Primes Intact Human Coronary Arteries and Cultured Coronary Smooth Muscle Cells to Double-Stranded RNA- and Self-RNA–Induced Inflammatory Responses by Upregulating TLR3 and Melanoma Differentiation-Associated Gene 5Ahmad U, Ali R, Lebastchi AH, Qin L, Lo SF, Yakimov AO, Khan SF, Choy JC, Geirsson A, Pober JS, Tellides G. IFN-γ Primes Intact Human Coronary Arteries and Cultured Coronary Smooth Muscle Cells to Double-Stranded RNA- and Self-RNA–Induced Inflammatory Responses by Upregulating TLR3 and Melanoma Differentiation-Associated Gene 5 The Journal Of Immunology 2010, 185: 1283-1294. PMID: 20562257, PMCID: PMC2902797, DOI: 10.4049/jimmunol.0902283.
  • 446: Dynamic Regulation of Micro RNAs in Ischemic Cardiac Remodeling and Heart FailureAli R, Kim R, Tellides G, Geirsson A. 446: Dynamic Regulation of Micro RNAs in Ischemic Cardiac Remodeling and Heart Failure The Journal Of Heart And Lung Transplantation 2009, 28: s220-s221. DOI: 10.1016/j.healun.2008.11.453.
  • Observational study of mortality risk stratification by ischemic presentation in patients with acute type A aortic dissection: the Penn classificationAugoustides J, Geirsson A, Szeto WY, Walsh EK, Cornelius B, Pochettino A, Bavaria JE. Observational study of mortality risk stratification by ischemic presentation in patients with acute type A aortic dissection: the Penn classification Nature Clinical Practice Cardiovascular Medicine 2008, 6: 140-146. PMID: 19065126, DOI: 10.1038/ncpcardio1417.
  • Fate of the Residual Distal and Proximal Aorta After Acute Type A Dissection Repair Using a Contemporary Surgical Reconstruction AlgorithmGeirsson A, Bavaria JE, Swarr D, Keane MG, Woo YJ, Szeto WY, Pochettino A. Fate of the Residual Distal and Proximal Aorta After Acute Type A Dissection Repair Using a Contemporary Surgical Reconstruction Algorithm The Annals Of Thoracic Surgery 2007, 84: 1955-1964. PMID: 18036916, DOI: 10.1016/j.athoracsur.2007.07.017.
  • Abstract 3056: Ischemia on Presentation Stratifies Mortality Risk in Surgery for Acute Type A DissectionAugoustides J, Geirsson A, Szeto W, Walsh L, Cornelius B, Pochettino A, Bavaria J. Abstract 3056: Ischemia on Presentation Stratifies Mortality Risk in Surgery for Acute Type A Dissection Circulation 2007, 116 DOI: 10.1161/circ.116.suppl_16.ii_684-d.
  • Significance of malperfusion syndromes prior to contemporary surgical repair for acute type A dissection: outcomes and need for additional revascularizationsGeirsson A, Szeto WY, Pochettino A, McGarvey ML, Keane MG, Woo YJ, Augoustides JG, Bavaria JE. Significance of malperfusion syndromes prior to contemporary surgical repair for acute type A dissection: outcomes and need for additional revascularizations European Journal Of Cardio-Thoracic Surgery 2007, 32: 255-262. PMID: 17500002, DOI: 10.1016/j.ejcts.2007.04.012.
  • Inhibition of alloresponse by a human trophoblast non-coding RNA suppressing class II transactivator promoter III and major histocompatibility class II expression in murine B-lymphocytesGeirsson A, Bothwell AL, Hammond GL. Inhibition of alloresponse by a human trophoblast non-coding RNA suppressing class II transactivator promoter III and major histocompatibility class II expression in murine B-lymphocytes The Journal Of Heart And Lung Transplantation 2004, 23: 1077-1081. PMID: 15454174, DOI: 10.1016/j.healun.2004.07.020.
  • Inhibition of T-lymphocyte stimulation by a trophoblast non-coding RNA suppressing MHC class II expression in murine B-cellsGeirsson A, Bothwell A, Hammond G, Hammond G. Inhibition of T-lymphocyte stimulation by a trophoblast non-coding RNA suppressing MHC class II expression in murine B-cells The Journal Of Heart And Lung Transplantation 2004, 23: s48. DOI: 10.1016/j.healun.2003.11.020.
  • Class II transactivator promoter activity is suppressed through regulation by a trophoblast noncoding RNA1Geirsson A, Paliwal I, Lynch RJ, Bothwell AL, Hammond GL. Class II transactivator promoter activity is suppressed through regulation by a trophoblast noncoding RNA1 Transplantation 2003, 76: 387-394. PMID: 12883198, DOI: 10.1097/01.tp.0000073612.04525.46.
  • Human trophoblast noncoding RNA suppresses CIITA promoter III activity in murine B-lymphocytesGeirsson A, Lynch RJ, Paliwal I, Bothwell AL, Hammond GL. Human trophoblast noncoding RNA suppresses CIITA promoter III activity in murine B-lymphocytes Biochemical And Biophysical Research Communications 2003, 301: 718-724. PMID: 12565840, DOI: 10.1016/s0006-291x(03)00028-7.
  • Potentiating effects of pertussis toxin on leukotriene C4 induced formation of inositol phosphate and prostacyclin in human umbilical vein endothelial cellsGeirsson A, Halldórsson H, Magnúsdóttir K, Kjeld M, Thorgeirsson G. Potentiating effects of pertussis toxin on leukotriene C4 induced formation of inositol phosphate and prostacyclin in human umbilical vein endothelial cells Journal Of Cellular Physiology 1998, 177: 103-108. PMID: 9731750, DOI: 10.1002/(sici)1097-4652(199810)177:1<103::aid-jcp11>3.0.co;2-e.

Clinical Trials

ConditionsStudy Title
Diseases of the Cardiovascular SystemDefining Exercise Hemodynamics and Function After Transcatheter Aortic Valve Replacement (DEFINE-TAVR) Study. (DEFINE-TAVR)
Diseases of the Cardiovascular SystemFREEZE-AFIB Post-Market Study
Diseases of the Cardiovascular SystemSafe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)
Diseases of the Cardiovascular SystemSafe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)
Diseases of the Cardiovascular SystemCorMatrix Cor TRICUSPID ECM Valve Replacement Study
Diseases of the Cardiovascular SystemEffect of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing CABG and/or Cardiac Valve Surgery (START)
Diseases of the Cardiovascular SystemMitraClip REPAIR MR Study
Diseases of the Cardiovascular SystemBotox type A for the prevention of POAF in open-chest cardiac surgery
Diseases of the Cardiovascular SystemNetwork for Cardiothoracic Surgical Investigations in Cardiovascular Medicine: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation after CABG (PACES)
Diseases of the Cardiovascular SystemTranscatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation (APOLLO)
Diseases of the Cardiovascular SystemTranscatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)
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