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Andrew Wang, MD/PhD, AB

Assistant Professor

Contact Information

Andrew Wang, MD/PhD, AB

Lab Location

Office Location

Extensive Research Description

Abbreviated publications (chronologic):

Wang A, Fairhurst AM, Tus K, Subramanian S, Liu Y, Lin F, Igarashi P, Zhou XJ, Batteux F, Wong D, Wakeland EK, Mohan C. CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus. J Immunol. 2009 Apr 1; 182(7): 4448-58.

Wang A, Guilpain P, Chong BF, Chouzenoux S, Guillevin L, Du Y, Zhou XJ, Lin F, Fairhurst AM, Boudreaux C, Roux C, Wakeland EK, Davis LS, Batteux F, Mohan C. Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus. Arthritis Rheum. 2010 Nov; 62(11): 3436-46.

Wang A, Huen SC, Luan HH, Yu S, Zhang C, Gallezot JD, Booth CJ, Medzhitov R. Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation. Cell. 2016 Sep 8; 166(6): 1512-1525

Wang A, Huen SC, Luan HH, Baker K, Rinder H, Booth CJ, Medhzitov R. Glucose metabolism mediates disease tolerance in cerebral malaria. PNAS. 2018 Oct 23;115(43):11042-11047.

Wang A, Luan HH, Medzhitov R. An evolutionary perspective on immunometabolism. Science. 2019 Jan 11;363(6423)

Wang A*, Pope S, Weinstein J, Yu S, Zhang C, Booth CJ, Medzhitov R*. Specific Sequences of Infectious Challenge Leads to Secondary Hemophagocytic Lymphohistiocytosis-like Disease in Mice. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2200-2209. * Co-corresponding

Wang A*, Medzhitov R*. Counting Calories: The Cost of Inflammation. Cell 2019 Apr 4;177(2):223-224. *Co-corresponding

Wang A*, Medzhitov R*. Not the usual suspect: type I interferon-responsive T cells drive infection-induced cachexia. Nat Immunol. 2019 Jun;20(6):666-667. *Co-corresponding

Wang A*, Luan HH, Hilliard B, Carvalho F, Rosen C, Ahasic A, Herzog E, Kang I, Pisani M, Yu S, Zhang C, Ring A, Young L, Medzhitov R*. GDF15 is an Inflammation-Induced Central Mediator of Tissue Tolerance. Cell. 2019. Aug 22;178(5):1231-1244.e11.

Uchendu SN, Wang A* . Less Pain, More Gain: Should Placebo Be a Clinical Therapeutic? Arthritis Rheumatol. 2020. Apr;72(4):511-514.

Qing H, Desrouleaux R, Israni-Winger K, Fogelman N, Zhang C, Rashad S, Palm NW, Sinha R, Piccioto MR, Perry RJ, Wang A* . Origin and function of stress-induced IL6 in murine models. Cell. 2020. Jun 27;S0092-8674(20)30687-5.

Research Interests

Inflammation; Metabolism; Psychoneuroimmunology; Neuroimmunomodulation

Clinical Trials