Research & Publications
Dr. Justice has done research in outcomes in chronic HIV infection, for the past 20 years. Her goal is to use HIV infection as a model for improving outcomes in chronic disease by studying the association between mutable mediators of clinical outcome in HIV and intervening on these mediators. She is the Principal Investigator on the Veterans Aging Cohort Study (VACS). This research, initially funded by career development awards from the National Institute on Aging and The Robert Wood Johnson Foundation, considers the complex roles of aging, symptoms, medical treatment, adherence, patient-provider relationships, disease severity, and medical and psychiatric comorbid illness in determining survival and quality of life for people with HIV infection. VACS has received 5 years of funding from NIAAA to conduct an expansion of the study to include HIV negative controls and additional study sites. The study is focused on understanding the likely interactive and overlapping role of alcohol use and abuse in determining outcomes among veterans aging with HIV infection and comparing this role to age-race-site matched HIV negative veterans.
Dr. Justice is also a nation-wide leader in HIV-associated cancers. Using the VA cohort of HIV-infected patients, which is the largest cohort in the US, she has studied cancer in HIV-infected patients over time and reported the changes of cancers in AIDS patients on retroviral therapy. Because it is also the oldest such cohort in the US, Dr. Justice was the first to identify many of the cancers in the aging population of HIV+ patients with suppressed viral load.
Specialized Terms: Chronic disease; HIV infection; Veterans Aging Cohort Study; Cancers in AIDS patients; Viral non-AIDS defining cancers
Extensive Research Description
Veterans Aging Cohort Study
Aging; Chronic Disease; Health Policy; Internal Medicine; Medical Oncology; Veterans; HIV Infections
Public Health Interests