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Alfred Lee, MD, PhD

Associate Professor of Medicine (Hematology); Director, Hematology/Oncology Fellowship Program

Contact Information

Alfred Lee, MD, PhD

Mailing Address

  • Hematology

    333 Cedar Street, PO Box 208028

    New Haven, CT, 06520-8028

    United States

Yale Medicine

Patient Care

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Coauthors

Selected Publications

  • Cost effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura.Goshua G, Sinha P, Hendrickson JE, Tormey CA, Bendapudi P, Lee AI. Cost effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura. Blood 2021, 137:969-976.
  • Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: A propensity score-matched analysis.Meizlish ML, Goshua G, Liu Y, Fine R, Amin K, Chang E, DeFilippo N, Keating C, Liu Y, Mankbadi M, McManus D, Wang SY, Price C, Bona RD, Ochoa Chaar CI, Chun HJ, Pine AB, Rinder HM, Siner JM, Neuberg DS, Owusu KA, Lee AI. Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: A propensity score-matched analysis. American Journal Of Hematology 2021, 96:471-479.
  • Cryptic Cachexia.Odio CD, O'Brien CR, Jacox J, Jain D, Lee AI. Cryptic Cachexia. The New England Journal Of Medicine 2020, 383:68-74.
  • Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study.Goshua G, Pine AB, Meizlish ML, Chang CH, Zhang H, Bahel P, Baluha A, Bar N, Bona RD, Burns AJ, Dela Cruz CS, Dumont A, Halene S, Hwa J, Koff J, Menninger H, Neparidze N, Price C, Siner JM, Tormey C, Rinder HM, Chun HJ, Lee AI. Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study. The Lancet. Haematology 2020, 7:e575-e582.
  • Trends and factors affecting the US adult hematology workforce: a mixed methods study.Sharma D, Wallace N, Levinsohn EA, Marshall AL, Kayoumi K, Madero J, Homer M, Reynolds R, Hafler J, Podoltsev NA, Lee AI. Trends and factors affecting the US adult hematology workforce: a mixed methods study. Blood Advances 2019, 3:3550-3561.
  • Associations between hematology/oncology fellows' training and mentorship experiences and hematology-only career plans.Masselink LE, Erikson CE, Connell NT, De Castro LM, Dent GA, Marshall AL, Naik RP, Nelson M, O'Connell CL, Rajasekhar A, Sharma D, Smith M, Lee AI. Associations between hematology/oncology fellows' training and mentorship experiences and hematology-only career plans. Blood Advances 2019, 3:3278-3286.
  • The next(gen) step in coagulation testing.Lee AI, Connors JM. The next(gen) step in coagulation testing. Blood 2019, 134:2002-2003.
  • A novel approach to the program evaluation committee.Schwartz AR, Siegel MD, Lee AI. A novel approach to the program evaluation committee. BMC Medical Education 2019, 19:465.
  • Evaluation of Polycythemia: A Teachable Moment.Djulbegovic M, Dugdale LS, Lee AI. Evaluation of Polycythemia: A Teachable Moment. JAMA Internal Medicine 2018, 178:128-130.
  • Whole-exome sequencing in evaluation of patients with venous thromboembolism.Lee EJ, Dykas DJ, Leavitt AD, Camire RM, Ebberink E, García de Frutos P, Gnanasambandan K, Gu SX, Huntington JA, Lentz SR, Mertens K, Parish CR, Rezaie AR, Sayeski PP, Cromwell C, Bar N, Halene S, Neparidze N, Parker TL, Burns AJ, Dumont A, Yao X, Chaar CIO, Connors JM, Bale AE, Lee AI. Whole-exome sequencing in evaluation of patients with venous thromboembolism. Blood Advances 2017, 1:1224-1237.
  • CLINICAL PROBLEM-SOLVING. The Hidden Lesion.Lee AI, Ochoa Chaar CI. CLINICAL PROBLEM-SOLVING. The Hidden Lesion. The New England Journal Of Medicine 2016, 374:2160-5.
  • Clinical problem-solving. Venting the spleen.Varughese N, Duong A, Emre S, Xu M, Lee AI. Clinical problem-solving. Venting the spleen. The New England Journal Of Medicine 2013, 369:1357-63.
  • Clinical problem-solving. A bird's-eye view of fever.Lee AI, Koo S, Vaidya A, Katz JT, Loscalzo J. Clinical problem-solving. A bird's-eye view of fever. The New England Journal Of Medicine 2011, 365:1727-32.

Clinical Trials

ConditionsStudy Title
Lymphoid LeukemiaA Phase II Study of Blinatumomab and POMP (Prednisone, Vincristine, Methotrexate, 6-Mercaptopurine) for Patients >/= 65 Years of Age With Newly Diagnosed Philadelphia-Chromosome Negative (Ph-) Acute Lymphoblastic Leukemia (ALL) and of Dasatinib, Prednisone and Blinatumomab for Patients >/= 65 Years of Age With Newly Diagnosed Philadelphia-Chromosome Positive (Ph+) ALL, Relapsed/Refractory Philadelphia-Chromosome Postive (Ph+) ALL, and Philadelphia-Chromosome-Like Signature (Ph-Like) ALL With Known or Presumed Activating Dastinib-Sensitive Mutations or Kinase Fusions (DSMKF)
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