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Adam V Wisnewski, PhD, D(ABMLI)

Senior Research Scientist in Medicine (Occupational Medicine)

Contact Information

Adam V Wisnewski, PhD, D(ABMLI)

Mailing Address

  • Occupational Health & Environmental Medicine

    PO Box 208056, 333 Cedar Street

    New Haven, CT 06520-8056

    United States

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Coauthors

Selected Publications

  • Delayed production of neutralizing antibodies correlates with fatal COVID-19.Lucas C, Klein J, Sundaram ME, Liu F, Wong P, Silva J, Mao T, Oh JE, Mohanty S, Huang J, Tokuyama M, Lu P, Venkataraman A, Park A, Israelow B, Vogels CBF, Muenker MC, Chang CH, Casanovas-Massana A, Moore AJ, Zell J, Fournier JB, Wyllie AL, Campbell M, Lee A, Chun HJ, Grubaugh ND, Schulz WL, Farhadian S, Dela Cruz C, Ring AM, Shaw AC, Wisnewski AV, Yildirim I, Ko AI, Omer S, Iwasaki A. Delayed production of neutralizing antibodies correlates with fatal COVID-19. Nature Medicine 2021, 27: 1178-1186. PMID: 33953384, PMCID: PMC8785364, DOI: 10.1038/s41591-021-01355-0.
  • Plasmodium infection induces cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein.Lapidus S, Liu F, Casanovas-Massana A, Dai Y, Huck JD, Lucas C, Klein J, Filler RB, Strine MS, Sy M, Deme AB, Badiane AS, Dieye B, Ndiaye IM, Diedhiou Y, Mbaye AM, Diagne CT, Vigan-Womas I, Mbengue A, Sadio BD, Diagne MM, Moore AJ, Mangou K, Diallo F, Sene SD, Pouye MN, Faye R, Diouf B, Nery N, Costa F, Reis M, Muenker MC, Hodson DZ, Mbarga Y, Katz BZ, Andrews JR, Campbell M, Srivathsan A, Kamath K, Baum-Jones E, Faye O, Sall AA, Vélez JCQ, Cappello M, Wilson M, Ben-Mamoun C, Somé FA, Dabiré RK, Moukoko CEE, Ouédraogo JB, Boum Y, Shon J, Ndiaye D, Wisnewski A, Parikh S, Iwasaki A, Wilen CB, Ko AI, Ring AM, Bei AK. Plasmodium infection induces cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein. MedRxiv : The Preprint Server For Health Sciences 2021 PMID: 34013301, PMCID: PMC8132281, DOI: 10.1101/2021.05.10.21256855.
  • Author Correction: Delayed production of neutralizing antibodies correlates with fatal COVID-19.Lucas C, Klein J, Sundaram ME, Liu F, Wong P, Silva J, Mao T, Oh JE, Mohanty S, Huang J, Tokuyama M, Lu P, Venkataraman A, Park A, Israelow B, Vogels CBF, Muenker MC, Chang CH, Casanovas-Massana A, Moore AJ, Zell J, Fournier JB, Wyllie AL, Campbell M, Lee AI, Chun HJ, Grubaugh ND, Schulz WL, Farhadian S, Dela Cruz C, Ring AM, Shaw AC, Wisnewski AV, Yildirim I, Ko AI, Omer SB, Iwasaki A. Author Correction: Delayed production of neutralizing antibodies correlates with fatal COVID-19. Nature Medicine 2021, 27: 1309. PMID: 34145437, PMCID: PMC8212078, DOI: 10.1038/s41591-021-01416-4.
  • Human IgG and IgA responses to COVID-19 mRNA vaccines.Wisnewski AV, Campillo Luna J, Redlich CA. Human IgG and IgA responses to COVID-19 mRNA vaccines. PloS One 2021, 16: e0249499. PMID: 34133415, PMCID: PMC8208542, DOI: 10.1371/journal.pone.0249499.
  • Associations of SARS-CoV-2 serum IgG with occupation and demographics of military personnel.Zell J, Wisnewski AV, Liu J, Klein J, Lucas C, Slade M, Iwasaki A, Redlich CA. Associations of SARS-CoV-2 serum IgG with occupation and demographics of military personnel. PloS One 2021, 16: e0251114. PMID: 34460832, PMCID: PMC8405017, DOI: 10.1371/journal.pone.0251114.
  • Immunogenic amino acid motifs and linear epitopes of COVID-19 mRNA vaccines.Wisnewski AV, Redlich CA, Liu J, Kamath K, Abad QA, Smith RF, Fazen L, Santiago R, Campillo Luna J, Martinez B, Baum-Jones E, Waitz R, Haynes WA, Shon JC. Immunogenic amino acid motifs and linear epitopes of COVID-19 mRNA vaccines. PloS One 2021, 16: e0252849. PMID: 34499652, PMCID: PMC8428655, DOI: 10.1371/journal.pone.0252849.
  • Analysis of Lung Gene Expression Reveals a Role for Cl- Channels in Diisocyanate-induced Airway Eosinophilia in a Mouse Model of Asthma Pathology.Wisnewski AV, Liu J, Redlich CA. Analysis of Lung Gene Expression Reveals a Role for Cl- Channels in Diisocyanate-induced Airway Eosinophilia in a Mouse Model of Asthma Pathology. American Journal Of Respiratory Cell And Molecular Biology 2020, 63: 25-35. PMID: 32101465, PMCID: PMC7328250, DOI: 10.1165/rcmb.2019-0400OC.
  • Molecular Characterization and Experimental Utility of Monoclonal Antibodies with Specificity for Aliphatic Di- and Polyisocyanates.Wisnewski AV, Liu J. Molecular Characterization and Experimental Utility of Monoclonal Antibodies with Specificity for Aliphatic Di- and Polyisocyanates. Monoclonal Antibodies In Immunodiagnosis And Immunotherapy 2020, 39: 66-73. PMID: 32302507, PMCID: PMC7310211, DOI: 10.1089/mab.2020.0006.
  • Kinetics of antibody responses dictate COVID-19 outcome.Lucas C, Klein J, Sundaram M, Liu F, Wong P, Silva J, Mao T, Oh JE, Tokuyama M, Lu P, Venkataraman A, Park A, Israelow B, Wyllie AL, Vogels CBF, Muenker MC, Casanovas-Massana A, Schulz WL, Zell J, Campbell M, Fournier JB, Grubaugh ND, Farhadian S, Wisnewski AV, Cruz CD, Omer S, Ko AI, Ring A, Iwasaki A. Kinetics of antibody responses dictate COVID-19 outcome. MedRxiv : The Preprint Server For Health Sciences 2020 PMID: 33398304, PMCID: PMC7781347, DOI: 10.1101/2020.12.18.20248331.
  • Development and Validation of LC-MS-MS Assay for the Determination of the Emerging Alkylating Agent Laromustine and Its Active Metabolite in Human Plasma.Nassar AF, Wisnewski AV, Wu T, Lam TT, King I. Development and Validation of LC-MS-MS Assay for the Determination of the Emerging Alkylating Agent Laromustine and Its Active Metabolite in Human Plasma. Journal Of Chromatographic Science 2019, 57: 195-203. PMID: 30395213, DOI: 10.1093/chromsci/bmy100.
  • Dilysine-Methylene Diphenyl Diisocyanate (MDI), a Urine Biomarker of MDI Exposure?Wisnewski AV, Nassar AF, Liu J, Bello D. Dilysine-Methylene Diphenyl Diisocyanate (MDI), a Urine Biomarker of MDI Exposure? Chemical Research In Toxicology 2019, 32: 557-565. PMID: 30724074, PMCID: PMC6465083, DOI: 10.1021/acs.chemrestox.8b00262.
  • LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.Wisnewski AV, Liu J, Nassar AF. LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate. EC Pharmacology And Toxicology 2019, 7: 205-219. PMID: 31143884, PMCID: PMC6536005.
  • Reaction products of hexamethylene diisocyanate vapors with "self" molecules in the airways of rabbits exposed via tracheostomy.Wisnewski AV, Kanyo J, Asher J, Goodrich JA, Barnett G, Patrylak L, Liu J, Redlich CA, Nassar AF. Reaction products of hexamethylene diisocyanate vapors with "self" molecules in the airways of rabbits exposed via tracheostomy. Xenobiotica; The Fate Of Foreign Compounds In Biological Systems 2018, 48: 488-497. PMID: 28489470, PMCID: PMC5863241, DOI: 10.1080/00498254.2017.1329569.
  • Polymerization of hexamethylene diisocyanate in solution and a 260.23 m/z [M+H]+ ion in exposed human cells.Wisnewski AV, Liu J, Redlich CA, Nassar AF. Polymerization of hexamethylene diisocyanate in solution and a 260.23 m/z [M+H]+ ion in exposed human cells. Analytical Biochemistry 2018, 543: 21-29. PMID: 29175138, PMCID: PMC5826792, DOI: 10.1016/j.ab.2017.11.017.
  • Mass spectrometry-based analysis of murine bronchoalveolar lavage fluid following respiratory exposure to 4,4'-methylene diphenyl diisocyanate aerosol.Hettick JM, Law BF, Lin CC, Wisnewski AV, Siegel PD. Mass spectrometry-based analysis of murine bronchoalveolar lavage fluid following respiratory exposure to 4,4'-methylene diphenyl diisocyanate aerosol. Xenobiotica; The Fate Of Foreign Compounds In Biological Systems 2018, 48: 626-636. PMID: 28629263, PMCID: PMC5864557, DOI: 10.1080/00498254.2017.1344791.
  • UPLC-MS for metabolomics: a giant step forward in support of pharmaceutical research.Nassar AF, Wu T, Nassar SF, Wisnewski AV. UPLC-MS for metabolomics: a giant step forward in support of pharmaceutical research. Drug Discovery Today 2017, 22: 463-470. PMID: 27919805, PMCID: PMC5721520, DOI: 10.1016/j.drudis.2016.11.020.
  • Population pharmacokinetic (PK) analysis of laromustine, an emerging alkylating agent, in cancer patients.Nassar AF, Wisnewski AV, King I. Population pharmacokinetic (PK) analysis of laromustine, an emerging alkylating agent, in cancer patients. Xenobiotica; The Fate Of Foreign Compounds In Biological Systems 2017, 47: 394-407. PMID: 27440490, DOI: 10.1080/00498254.2016.1201703.
  • Automation of sample preparation for mass cytometry barcoding in support of clinical research: protocol optimization.Nassar AF, Wisnewski AV, Raddassi K. Automation of sample preparation for mass cytometry barcoding in support of clinical research: protocol optimization. Analytical And Bioanalytical Chemistry 2017, 409: 2363-2372. PMID: 28124752, PMCID: PMC5863240, DOI: 10.1007/s00216-017-0182-4.
  • Corrigendum to "Identification of novel reaction products of methylene-biS-phenylisocyanate ("MDI") with oxidized glutathione in aqueous solution and also during incubation of MDI with a murine hepatic S9 fraction" [Toxicol. In vitro (2016) 97-104].Wisnewski AV, Liu J, Nassar AF. Corrigendum to "Identification of novel reaction products of methylene-biS-phenylisocyanate ("MDI") with oxidized glutathione in aqueous solution and also during incubation of MDI with a murine hepatic S9 fraction" [Toxicol. In vitro (2016) 97-104]. Toxicology In Vitro : An International Journal Published In Association With BIBRA 2017, 38: 193. PMID: 27784537, DOI: 10.1016/j.tiv.2016.10.008.
  • Mass cytometry moving forward in support of clinical research: advantages and considerations.Nassar AF, Wisnewski AV, Raddassi K. Mass cytometry moving forward in support of clinical research: advantages and considerations. Bioanalysis 2016, 8: 255-7. PMID: 26847541, DOI: 10.4155/bio.15.257.
  • Immunochemical detection of the occupational allergen, methylene diphenyl diisocyanate (MDI), in situ.Wisnewski AV, Liu J. Immunochemical detection of the occupational allergen, methylene diphenyl diisocyanate (MDI), in situ. Journal Of Immunological Methods 2016, 429: 60-5. PMID: 26690039, PMCID: PMC4753098, DOI: 10.1016/j.jim.2015.12.008.
  • Progress in automation of mass cytometry barcoding for drug development.Nassar AF, Wisnewski AV, Raddassi K. Progress in automation of mass cytometry barcoding for drug development. Bioanalysis 2016, 8: 1429-35. PMID: 27323800, DOI: 10.4155/bio-2016-0135.
  • Identification of novel reaction products of methylene-bis-phenylisocyanate ("MDI") with oxidized glutathione in aqueous solution and also during incubation of MDI with a murine hepatic S9 fraction.Wisnewski AV, Liu J, Nassar AF. Identification of novel reaction products of methylene-bis-phenylisocyanate ("MDI") with oxidized glutathione in aqueous solution and also during incubation of MDI with a murine hepatic S9 fraction. Toxicology In Vitro : An International Journal Published In Association With BIBRA 2016, 36: 97-104. PMID: 27453132, PMCID: PMC5010927, DOI: 10.1016/j.tiv.2016.07.011.
  • The influence of diisocyanate antigen preparation methodology on monoclonal and serum antibody recognition.Hagerman LM, Law BF, Bledsoe TA, Hettick JM, Kashon ML, Lemons AR, Wisnewski AV, Siegel PD. The influence of diisocyanate antigen preparation methodology on monoclonal and serum antibody recognition. Journal Of Occupational And Environmental Hygiene 2016, 13: 829-39. PMID: 27124286, PMCID: PMC5016257, DOI: 10.1080/15459624.2016.1183013.
  • In vitro cleavage of diisocyanate-glutathione conjugates by human gamma-glutamyl transpeptidase-1.Wisnewski AV, Liu J, Nassar AF. In vitro cleavage of diisocyanate-glutathione conjugates by human gamma-glutamyl transpeptidase-1. Xenobiotica; The Fate Of Foreign Compounds In Biological Systems 2016, 46: 726-32. PMID: 26678254, PMCID: PMC4848134, DOI: 10.3109/00498254.2015.1118576.
  • Biotransformation and Rearrangement of Laromustine.Nassar AE, Wisnewski AV, King I. Biotransformation and Rearrangement of Laromustine. Drug Metabolism And Disposition: The Biological Fate Of Chemicals 2016, 44: 1349-63. PMID: 27278961, DOI: 10.1124/dmd.116.069823.
  • Glutathione reaction products with a chemical allergen, methylene-diphenyl diisocyanate, stimulate alternative macrophage activation and eosinophilic airway inflammation.Wisnewski AV, Liu J, Colangelo CM. Glutathione reaction products with a chemical allergen, methylene-diphenyl diisocyanate, stimulate alternative macrophage activation and eosinophilic airway inflammation. Chemical Research In Toxicology 2015, 28: 729-37. PMID: 25635619, PMCID: PMC4667722, DOI: 10.1021/tx5005002.
  • Metabolic disposition of the anti-cancer agent [(14)C]laromustine in male rats.Nassar AF, Wisnewski A, King I. Metabolic disposition of the anti-cancer agent [(14)C]laromustine in male rats. Xenobiotica; The Fate Of Foreign Compounds In Biological Systems 2015, 45: 711-21. PMID: 25798740, PMCID: PMC4681490, DOI: 10.3109/00498254.2015.1016475.
  • Impact of recent innovations in the use of mass cytometry in support of drug development.Nassar AF, Ogura H, Wisnewski AV. Impact of recent innovations in the use of mass cytometry in support of drug development. Drug Discovery Today 2015, 20: 1169-75. PMID: 26092491, PMCID: PMC4668584, DOI: 10.1016/j.drudis.2015.06.001.
  • Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: initial one-year follow-up.Gui W, Wisnewski AV, Neamtiu I, Gurzau E, Sparer JA, Stowe MH, Liu J, Slade MD, Rusu OA, Redlich CA. Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: initial one-year follow-up. American Journal Of Industrial Medicine 2014, 57: 1207-15. PMID: 25266741, PMCID: PMC4198484, DOI: 10.1002/ajim.22385.
  • Connecting glutathione with immune responses to occupational methylene diphenyl diisocyanate exposure.Wisnewski AV, Liu J, Redlich CA. Connecting glutathione with immune responses to occupational methylene diphenyl diisocyanate exposure. Chemico-biological Interactions 2013, 205: 38-45. PMID: 23791970, PMCID: PMC3767171, DOI: 10.1016/j.cbi.2013.06.005.
  • Hexamethylene diisocyanate (HDI) vapor reactivity with glutathione and subsequent transfer to human albumin.Wisnewski AV, Mhike M, Hettick JM, Liu J, Siegel PD. Hexamethylene diisocyanate (HDI) vapor reactivity with glutathione and subsequent transfer to human albumin. Toxicology In Vitro : An International Journal Published In Association With BIBRA 2013, 27: 662-71. PMID: 23178851, PMCID: PMC3587365, DOI: 10.1016/j.tiv.2012.11.013.
  • Molecular determinants of humoral immune specificity for the occupational allergen, methylene diphenyl diisocyanate.Wisnewski AV, Liu J. Molecular determinants of humoral immune specificity for the occupational allergen, methylene diphenyl diisocyanate. Molecular Immunology 2013, 54: 233-7. PMID: 23295252, PMCID: PMC3563841, DOI: 10.1016/j.molimm.2012.11.017.
  • Biomonitoring Hexamethylene diisocyanate (HDI) exposure based on serum levels of HDI-specific IgG.Wisnewski AV, Stowe MH, Nerlinger A, Opare-Addo P, Decamp D, Kleinsmith CR, Redlich CA. Biomonitoring Hexamethylene diisocyanate (HDI) exposure based on serum levels of HDI-specific IgG. The Annals Of Occupational Hygiene 2012, 56: 901-10. PMID: 22449630, PMCID: PMC3471419, DOI: 10.1093/annhyg/mes024.
  • Vapor conjugation of toluene diisocyanate to specific lysines of human albumin.Hettick JM, Siegel PD, Green BJ, Liu J, Wisnewski AV. Vapor conjugation of toluene diisocyanate to specific lysines of human albumin. Analytical Biochemistry 2012, 421: 706-11. PMID: 22206939, PMCID: PMC3324820, DOI: 10.1016/j.ab.2011.12.013.
  • Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses.Wisnewski AV, Xu L, Robinson E, Liu J, Redlich CA, Herrick CA. Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses. Journal Of Occupational Medicine And Toxicology (London, England) 2011, 6: 6. PMID: 21414210, PMCID: PMC3068988, DOI: 10.1186/1745-6673-6-6.
  • Toluene diisocyanate reactivity with glutathione across a vapor/liquid interface and subsequent transcarbamoylation of human albumin.Wisnewski AV, Hettick JM, Siegel PD. Toluene diisocyanate reactivity with glutathione across a vapor/liquid interface and subsequent transcarbamoylation of human albumin. Chemical Research In Toxicology 2011, 24: 1686-93. PMID: 21806041, PMCID: PMC3321232, DOI: 10.1021/tx2002433.
  • Pathogenesis and disease mechanisms of occupational asthma.Lummus ZL, Wisnewski AV, Bernstein DI. Pathogenesis and disease mechanisms of occupational asthma. Immunology And Allergy Clinics Of North America 2011, 31: 699-716, vi. PMID: 21978852, PMCID: PMC4683932, DOI: 10.1016/j.iac.2011.07.008.
  • Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate.Wisnewski AV, Liu J, Redlich CA. Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate. Analytical Biochemistry 2010, 400: 251-8. PMID: 20123080, PMCID: PMC3106273, DOI: 10.1016/j.ab.2010.01.037.
  • Pro/Con debate: Is occupational asthma induced by isocyanates an immunoglobulin E-mediated disease?Wisnewski AV, Jones M. Pro/Con debate: Is occupational asthma induced by isocyanates an immunoglobulin E-mediated disease? Clinical And Experimental Allergy : Journal Of The British Society For Allergy And Clinical Immunology 2010, 40: 1155-62. PMID: 20545707, PMCID: PMC3121887, DOI: 10.1111/j.1365-2222.2010.03550.x.
  • Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI-albumin conjugates.Wisnewski AV, Liu Q, Liu J, Redlich CA. Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI-albumin conjugates. Clinical And Experimental Allergy : Journal Of The British Society For Allergy And Clinical Immunology 2008, 38: 957-67. PMID: 18498542, PMCID: PMC3131007, DOI: 10.1111/j.1365-2222.2008.02982.x.
  • Developments in laboratory diagnostics for isocyanate asthma.Wisnewski AV. Developments in laboratory diagnostics for isocyanate asthma. Current Opinion In Allergy And Clinical Immunology 2007, 7: 138-45. PMID: 17351466, PMCID: PMC3131002, DOI: 10.1097/ACI.0b013e3280895d22.
  • Respiratory symptoms, sensitization, and exposure response relationships in spray painters exposed to isocyanates.Pronk A, Preller L, Raulf-Heimsoth M, Jonkers IC, Lammers JW, Wouters IM, Doekes G, Wisnewski AV, Heederik D. Respiratory symptoms, sensitization, and exposure response relationships in spray painters exposed to isocyanates. American Journal Of Respiratory And Critical Care Medicine 2007, 176: 1090-7. PMID: 17656675, PMCID: PMC2176099, DOI: 10.1164/rccm.200702-215OC.
  • Biophysical determinants of toluene diisocyanate antigenicity associated with exposure and asthma.Ye YM, Kim CW, Kim HR, Kim HM, Suh CH, Nahm DH, Park HS, Redlich CA, Wisnewski AV. Biophysical determinants of toluene diisocyanate antigenicity associated with exposure and asthma. The Journal Of Allergy And Clinical Immunology 2006, 118: 885-91. PMID: 17030242, DOI: 10.1016/j.jaci.2006.06.026.
  • Suburban leptospirosis: atypical lymphocytosis and gamma-delta T cell response.Barry M, Wisnewski AV, Matthias MA, Inouye SK, Vinetz JM. Suburban leptospirosis: atypical lymphocytosis and gamma-delta T cell response. Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America 2006, 43: 1304-7. PMID: 17051497, DOI: 10.1086/508537.
  • Glutathione protects human airway proteins and epithelial cells from isocyanates.Wisnewski AV, Liu Q, Liu J, Redlich CA. Glutathione protects human airway proteins and epithelial cells from isocyanates. Clinical And Experimental Allergy : Journal Of The British Society For Allergy And Clinical Immunology 2005, 35: 352-7. PMID: 15784115, DOI: 10.1111/j.1365-2222.2005.02185.x.
  • Isocyanate vapor-induced antigenicity of human albumin.Wisnewski AV, Stowe MH, Cartier A, Liu Q, Liu J, Chen L, Redlich CA. Isocyanate vapor-induced antigenicity of human albumin. The Journal Of Allergy And Clinical Immunology 2004, 113: 1178-84. PMID: 15208602, DOI: 10.1016/j.jaci.2004.03.009.
  • Human gamma/delta T-cell proliferation and IFN-gamma production induced by hexamethylene diisocyanate.Wisnewski AV, Herrick CA, Liu Q, Chen L, Bottomly K, Redlich CA. Human gamma/delta T-cell proliferation and IFN-gamma production induced by hexamethylene diisocyanate. The Journal Of Allergy And Clinical Immunology 2003, 112: 538-46. PMID: 13679813, DOI: 10.1016/s0091-6749(03)01865-7.
  • Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation.Herrick CA, Das J, Xu L, Wisnewski AV, Redlich CA, Bottomly K. Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation. The Journal Of Allergy And Clinical Immunology 2003, 111: 1087-94. PMID: 12743574, DOI: 10.1067/mai.2003.1413.
  • Recent developments in diisocyanate asthma.Liu Q, Wisnewski AV. Recent developments in diisocyanate asthma. Annals Of Allergy, Asthma & Immunology : Official Publication Of The American College Of Allergy, Asthma, & Immunology 2003, 90: 35-41. PMID: 12772950, DOI: 10.1016/s1081-1206(10)61647-x.
  • Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies.Wisnewski AV, Liu Q, Miller JJ, Magoski N, Redlich CA. Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies. Environmental Health Perspectives 2002, 110: 901-7. PMID: 12204825, PMCID: PMC1240990, DOI: 10.1289/ehp.02110901.
  • Mouse models of diisocyanate asthma.Redlich CA, Wisnewski AV, Gordon T. Mouse models of diisocyanate asthma. American Journal Of Respiratory Cell And Molecular Biology 2002, 27: 385-90. PMID: 12356570, DOI: 10.1165/rcmb.F249.
  • A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challenge.Herrick CA, Xu L, Wisnewski AV, Das J, Redlich CA, Bottomly K. A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challenge. The Journal Of Allergy And Clinical Immunology 2002, 109: 873-8. PMID: 11994714, DOI: 10.1067/mai.2002.123533.
  • Diisocyanate-exposed auto body shop workers: a one-year follow-up.Redlich CA, Stowe MH, Coren BA, Wisnewski AV, Holm CT, Cullen MR. Diisocyanate-exposed auto body shop workers: a one-year follow-up. American Journal Of Industrial Medicine 2002, 42: 511-8. PMID: 12439874, DOI: 10.1002/ajim.10143.
  • Subclinical immunologic and physiologic responses in hexamethylene diisocyanate-exposed auto body shop workers.Redlich CA, Stowe MH, Wisnewski AV, Eisen EA, Karol MH, Lemus R, Holm CT, Chung JS, Sparer J, Liu Y, Woskie SR, Appiah-Pippim J, Gore R, Cullen MR. Subclinical immunologic and physiologic responses in hexamethylene diisocyanate-exposed auto body shop workers. American Journal Of Industrial Medicine 2001, 39: 587-97. PMID: 11385643, DOI: 10.1002/ajim.1058.
  • Human gamma/delta T-cell lines derived from airway biopsies.Wisnewski AV, Cain H, Magoski N, Wang H, Holm CT, Redlich CA. Human gamma/delta T-cell lines derived from airway biopsies. American Journal Of Respiratory Cell And Molecular Biology 2001, 24: 332-8. PMID: 11245633, DOI: 10.1165/ajrcmb.24.3.4325.
  • Recent developments in diisocyanate asthma.Wisnewski AV, Redlich CA. Recent developments in diisocyanate asthma. Current Opinion In Allergy And Clinical Immunology 2001, 1: 169-75. PMID: 11964686, DOI: 10.1097/01.all.0000011003.36723.d8.
  • Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivo.Wisnewski AV, Srivastava R, Herick C, Xu L, Lemus R, Cain H, Magoski NM, Karol MH, Bottomly K, Redlich CA. Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivo. American Journal Of Respiratory And Critical Care Medicine 2000, 162: 2330-6. PMID: 11112159, DOI: 10.1164/ajrccm.162.6.2002086.
  • Reply to letter to the editor concerning Gui et al. Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory.Wisnewski AV, Redlich CA. Reply to letter to the editor concerning Gui et al. Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory. American Journal Of Industrial Medicine 2021, 64: 1055-1056. PMID: 34647343, DOI: 10.1002/ajim.23299.
  • Human hybridoma generation by hypo-osmolar electrofusion: characterization of human monoclonal antibodies to Schistosoma mansoni parasite antigens.Klock G, Wisnewski AV, el-Bassiouni EA, Ramadan MI, Gessner P, Zimmermann U, Kresina TF. Human hybridoma generation by hypo-osmolar electrofusion: characterization of human monoclonal antibodies to Schistosoma mansoni parasite antigens. Hybridoma 1992, 11: 469-81. PMID: 1398684, DOI: 10.1089/hyb.1992.11.469.
  • An immunoregulatory human monoclonal antibody in schistosomiasis japonica.Kresina TF, Guan XH, Posner M, Wisnewski A, Olds GR. An immunoregulatory human monoclonal antibody in schistosomiasis japonica. Human Antibodies And Hybridomas 1991, 2: 42-5. PMID: 1651785.
  • Induction of protective immunity to schistosomiasis with immunologically cross-reactive Lumbricus molecules.Wisnewski AV, Kresina TF. Induction of protective immunity to schistosomiasis with immunologically cross-reactive Lumbricus molecules. International Journal For Parasitology 1995, 25: 503-10. PMID: 7543459, DOI: 10.1016/0020-7519(94)00132-8.
  • Human monoclonal antibodies heterogeneously express a human cross-reactive idiotype associated with immune function in Schistosoma japonicum infection.Wisnewski AV, Olds GR, Kresina TF. Human monoclonal antibodies heterogeneously express a human cross-reactive idiotype associated with immune function in Schistosoma japonicum infection. Human Antibodies And Hybridomas 1994, 5: 178-82. PMID: 7756581.
  • Human monoclonal antibodies against Cryptosporidium parvum generated by hypo-osmolar electrofusion.Flanigan TP, Wisnewski A, Wiest PM, Johnson J, Tzipori S, Hamer D, Lam N, Kresina TF. Human monoclonal antibodies against Cryptosporidium parvum generated by hypo-osmolar electrofusion. Transactions Of The Association Of American Physicians 1993, 106: 86-90. PMID: 8036749.
  • Induction of hepatic pathology in SCID-Hu mice engrafted with peripheral blood lymphocytes of patients with Schistosomiasis japonica.Kresina TF, Wisnewski A, Love-Homan L, Ramirez B, Neil GA. Induction of hepatic pathology in SCID-Hu mice engrafted with peripheral blood lymphocytes of patients with Schistosomiasis japonica. The Journal Of Infectious Diseases 1994, 170: 733-6. PMID: 8077739, DOI: 10.1093/infdis/170.3.733.
  • Human antibody variable region gene usage in HIV-1 infection.Wisnewski A, Cavacini L, Posner M. Human antibody variable region gene usage in HIV-1 infection. Journal Of Acquired Immune Deficiency Syndromes And Human Retrovirology : Official Publication Of The International Retrovirology Association 1996, 11: 31-8. PMID: 8528730, DOI: 10.1097/00042560-199601010-00004.
  • Function and expression of a human idiotypic network in Schistosomiasis japonica.Wisnewski AV, Olds GR, Johnson JH, Ramirez B, Kresina TF. Function and expression of a human idiotypic network in Schistosomiasis japonica. Parasite Immunology 1996, 18: 439-47. PMID: 9226679, DOI: 10.1111/j.1365-3024.1996.tb01027.x.
  • In vitro inhibition of Cryptosporidium parvum infection by human monoclonal antibodies.Elliot BC, Wisnewski AV, Johnson J, Fenwick-Smith D, Wiest P, Hamer D, Kresina T, Flanigan TP. In vitro inhibition of Cryptosporidium parvum infection by human monoclonal antibodies. Infection And Immunity 1997, 65: 3933-5. PMID: 9284173, PMCID: PMC175560, DOI: 10.1128/iai.65.9.3933-3935.1997.
  • Phase I study of a human monoclonal antibody directed against the CD4-binding site of HIV type 1 glycoprotein 120.Cavacini LA, Samore MH, Gambertoglio J, Jackson B, Duval M, Wisnewski A, Hammer S, Koziel C, Trapnell C, Posner MR. Phase I study of a human monoclonal antibody directed against the CD4-binding site of HIV type 1 glycoprotein 120. AIDS Research And Human Retroviruses 1998, 14: 545-50. PMID: 9591708, DOI: 10.1089/aid.1998.14.545.
  • Isocyanate-conjugated human lung epithelial cell proteins: A link between exposure and asthma?Wisnewski AV, Lemus R, Karol MH, Redlich CA. Isocyanate-conjugated human lung epithelial cell proteins: A link between exposure and asthma? The Journal Of Allergy And Clinical Immunology 1999, 104: 341-7. PMID: 10452755, DOI: 10.1016/s0091-6749(99)70377-5.
  • A human anti-HIV autoantibody enhances EBV transformation and HIV infection.Cavacini LA, Wisnewski A, Peterson JE, Montefiori D, Emes C, Duval M, Kingsbury G, Wang A, Scadden D, Posner MR. A human anti-HIV autoantibody enhances EBV transformation and HIV infection. Clinical Immunology (Orlando, Fla.) 1999, 93: 263-73. PMID: 10600338, DOI: 10.1006/clim.1999.4790.
  • Development of immunoassays for biomonitoring of hexamethylene diisocyanate exposure.Lemus R, Lukinskeine L, Bier ME, Wisnewski AV, Redlich CA, Karol MH. Development of immunoassays for biomonitoring of hexamethylene diisocyanate exposure. Environmental Health Perspectives 2001, 109: 1103-8. PMID: 11712993, PMCID: PMC1240469, DOI: 10.1289/ehp.011091103.
  • Diisocyanate conjugate and immunoassay characteristics influence detection of specific antibodies in HDI-exposed workers.Campo P, Wisnewski AV, Lummus Z, Cartier A, Malo JL, Boulet LP, Bernstein DI. Diisocyanate conjugate and immunoassay characteristics influence detection of specific antibodies in HDI-exposed workers. Clinical And Experimental Allergy : Journal Of The British Society For Allergy And Clinical Immunology 2007, 37: 1095-102. PMID: 17581205, DOI: 10.1111/j.1365-2222.2007.02745.x.
  • Development and utilization of a surrogate SARS-CoV-2 viral neutralization assay to assess mRNA vaccine responses.Wisnewski AV, Liu J, Lucas C, Klein J, Iwasaki A, Cantley L, Fazen L, Campillo Luna J, Slade M, Redlich CA. Development and utilization of a surrogate SARS-CoV-2 viral neutralization assay to assess mRNA vaccine responses. PloS One 2022, 17: e0262657. PMID: 35041700, PMCID: PMC8765639, DOI: 10.1371/journal.pone.0262657.
  • Severe asthma and death in a worker using methylene diphenyl diisocyanate MDI asthma death.Wisnewski AV, Cooney R, Hodgson M, Giese K, Liu J, Redlich CA. Severe asthma and death in a worker using methylene diphenyl diisocyanate MDI asthma death. American Journal Of Industrial Medicine 2022, 65: 166-172. PMID: 35028957, PMCID: PMC8846433, DOI: 10.1002/ajim.23323.
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