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Abhijeet Gummadavelli, MD

Hospital Resident

Contact Information

Abhijeet Gummadavelli, MD

Research Summary

Temporal lobe seizures are the most common form of localized epilepsy. How do focal seizures impair consciousness? We propose a “network inhibition hypothesis” in which temporal lobe seizures inhibit subcortical arousal systems, causing depressed cortical function. In support of this hypothesis, we found sleep-like changes in the cortex with intracranial EEG and SPECT during temporal lobe seizures. I am involved in translational research in animal models and in patients to reveal the fundamental mechanisms of these changes, and to test novel neuromodulatory approaches.

Coauthors

Research Interests

Neurosciences

Selected Publications