Section Chief
Professor of Radiology and Biomedical Imaging; Division Chief Cardiothoracic Imaging, Radiology & Biomedical Imaging
Cardiothoracic Imaging
Cardiacthoracic Imaging at Yale School of Medicine is a joint venture of the departments of Radiology & Biomedical Imaging and Cardiovascular Medicine. We specialize in all aspects of cardiovascular issues in newborns, children and adults. We provide a full range of diagnostic examinations for Yale New-Haven Hospital and its satellite centers, Park Avenue Medical Center, Saint Raphael Campus, and the Shoreline Medical Center.
Our Exertise
- Cardiac MRI
- Cardiac Stress MRI
- Cardiac Magnetic Resonance Angiography (MRA)
- Femoral MRA
- Coronary Computed Tomography Angiography (CCTA)
- Functional Cardiac CT in 4-D
- Structural Cardiac CT
- CTA, including thoracic, abdominal and extremities
- FFRct analysis
- Calcium scoring
- CT scans for coronary heart disease
Education
The thoracic imaging section is an academic division that is dedicated to teaching thoracic imaging to Yale medical students, residents, and clinicians. The department of radiology also hosts visiting students and physicians from other institutions locally, nationally and internationally. The Cardiothoracic Imaging Fellowship encompasses 6 months of dedicated training in thoracic imaging and 6 months of dedicated training in cardiac imaging. The section takes part in daily clinical-radiologic teaching rounds as well as weekly multidisciplinary conferences.
Leadership
Publications
2025
Cardiac Magnetic Resonance Imaging in Immune Checkpoint Inhibitor–Related Myocarditis
Hammer M, Tysarowski M, Fuss C, Bader A. Cardiac Magnetic Resonance Imaging in Immune Checkpoint Inhibitor–Related Myocarditis. Echocardiography 2025, 42: e70131. PMID: 40067334, DOI: 10.1111/echo.70131.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsImmune-related adverse eventsImmune checkpoint inhibitorsCardiac magnetic resonance imagingMagnetic resonance imagingAssociated with immune-related adverse eventsCardiac immune-related adverse eventsMechanisms of immune checkpoint inhibitorsICI-associated myocarditisICI-related myocarditisResonance imagingPersonalized cancer immunotherapySevere cardiovascular complicationsImmune tolerance pathwayCheckpoint inhibitorsCancer immunotherapyCardiac complicationsCombination therapyTumor cytotoxicityClinical presentationCardiovascular complicationsAdverse eventsTherapeutic efficacyOncological treatmentTherapeutic strategiesMyocarditisUsing Radiology as a Screening Tool to Identify Intimate Partner Violence
Lenehan P, Tang A, Watane G, Gujrathi R, Park H, Gosangi B, Thomas R, Franco F, Patel K, Warsofsky I, Rosner B, Khurana B. Using Radiology as a Screening Tool to Identify Intimate Partner Violence. Journal Of The American College Of Radiology 2025, 22: 395-404. PMID: 40044319, PMCID: PMC11887577, DOI: 10.1016/j.jacr.2025.01.003.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAdjusted incidence rate ratiosEmergency departmentRetrospective case-control studyImaging utilization patternsEvident injuriesCox proportional hazards regressionRace-matched controlsCase-control studyTime-to-event analysisProportional hazards regressionImaging utilizationIncidence rate ratiosCumulative incidenceAnatomical sitesScreening mammogramsHazards regressionOdds ratioImaging studiesIntimate partner violencePatientsInjury patternsLogistic regressionInjuryOrgan systemsPoisson regressionLow-Dose CT of the Chest: Is High-Risk Population Screening for Both Lung Cancer and Cardiovascular Disease Possible?
Fuss C. Low-Dose CT of the Chest: Is High-Risk Population Screening for Both Lung Cancer and Cardiovascular Disease Possible? Radiology 2025, 314: e250215. PMID: 39964272, DOI: 10.1148/radiol.250215.Peer-Reviewed Original ResearchAltmetric
2024
CT for Congenital Heart Disease
Fuss C. CT for Congenital Heart Disease. 2024, 277-293. DOI: 10.1007/978-981-97-6919-3_21.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseHeart diseaseEvaluation of congenital heart diseaseManagement of congenital heart diseaseContrast doseAffected patientsBirth defectsStages of repairRadiation exposureAltered physiologySmall organ sizeCT roleDiseaseVariable stagesCongenitallyPatientsCTDoseSpatial image resolutionComplexity of defectsBirthMA08.12 Semi-Sold Lung Nodule Growth Rates, Need for Treatment, and Cancer-Specific Verses All-Cause Mortality in a Large North American Population
Woodard G, Kane E, Prince S, Blasberg J, Dhanasopon A, Boffa D, Mase V, Dacic S, Bader A, Detterbeck F. MA08.12 Semi-Sold Lung Nodule Growth Rates, Need for Treatment, and Cancer-Specific Verses All-Cause Mortality in a Large North American Population. Journal Of Thoracic Oncology 2024, 19: s87. DOI: 10.1016/j.jtho.2024.09.156.Peer-Reviewed Original ResearchLi-Fraumeni Syndrome: Imaging Features and Guidelines.
Gosangi B, Dixe de Oliveira Santo I, Keraliya A, Wang Y, Irugu D, Thomas R, Khandelwal A, Rubinowitz A, Bader A. Li-Fraumeni Syndrome: Imaging Features and Guidelines. RadioGraphics 2024, 44: e230202. PMID: 39024172, DOI: 10.1148/rg.230202.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsLi-Fraumeni syndromeLifetime risk of cancerRare autosomal dominant familial cancer syndromeIncreased riskRisk of cancerTreated with total mastectomyAutosomal dominant familial cancer syndromeImaging features of tumorsFamilial cancer syndromeWhole-body MRIAnnual screeningFeatures of tumorsCancer syndromesLifetime riskP53 transcription factorLi-FraumeniAdrenocortical cancerTotal mastectomyPrimary cancerBreast malignancyImaging guidelinesBreast cancerGermline mutationsColon cancerManagement guidelinesLetter to the Editor: “Silent myocardial infarction fatty scars detected by coronary calcium score CT scan in diabetic patients without a history of coronary heart disease”
Bader A, Haramati L. Letter to the Editor: “Silent myocardial infarction fatty scars detected by coronary calcium score CT scan in diabetic patients without a history of coronary heart disease”. European Radiology 2024, 35: 215-217. PMID: 38995379, DOI: 10.1007/s00330-024-10912-3.Peer-Reviewed Original ResearchDisorders with Ophthalmic and Thoracic Involvement.
Gosangi B, Lang P, Johnson M, Zukerman R, Tu L, Traube L, Bader A, Rubinowitz A. Disorders with Ophthalmic and Thoracic Involvement. RadioGraphics 2024, 44: e230132. PMID: 38870047, DOI: 10.1148/rg.230132.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsClinical manifestationsExamination of family membersEhlers-Danlos syndromeAffecting patient outcomesAcute sarcoidosisOphthalmologic examinationThoracic symptomsDry eyeThoracic involvementOphthalmological symptomsOphthalmologic manifestationsEye symptomsMarfan syndromeSjogren's syndromeImaging findingsRadiological studiesLung diseasePatient outcomesEhlers-DanlosFamily membersMultimodal imagingSystem conditionsSyndromeThoracicSarcoidosisNext-generation digital chest tomosynthesis
Gange C, Ku J, Gosangi B, Liu J, Maolinbay M. Next-generation digital chest tomosynthesis. Journal Of Clinical Imaging Science 2024, 14: 22. PMID: 38975057, PMCID: PMC11225395, DOI: 10.25259/jcis_4_2024.Peer-Reviewed Original ResearchAltmetricConceptsRadiation doseLow dose chest CTLung phantomLung nodulesEffective radiation dosePlane resolutionLow radiation doseLow dose CTPhantomSimulated pulmonary nodulesChest CTChest radiologistsHealthy volunteersPulmonary nodulesDose CTAnatomical locationNodule detectionImaging characteristicsTomosynthesisNodulesLungDoseDetect lung nodulesDevicesPotential utilityThe Proposed Ninth Edition TNM Classification of Lung Cancer
Detterbeck F, Woodard G, Bader A, Dacic S, Grant M, Park H, Tanoue L. The Proposed Ninth Edition TNM Classification of Lung Cancer. CHEST Journal 2024, 166: 882-895. PMID: 38885896, DOI: 10.1016/j.chest.2024.05.026.Peer-Reviewed Original ResearchCitationsAltmetricImmunological and microbial shifts in the aging rhesus macaque lung during nontuberculous mycobacterial infection
Cinco I, Napier E, Rhoades N, Davies M, Allison D, Kohama S, Bermudez L, Winthrop K, Fuss C, Spindel E, Messaoudi I. Immunological and microbial shifts in the aging rhesus macaque lung during nontuberculous mycobacterial infection. MBio 2024, 15: e00829-24. PMID: 38771046, PMCID: PMC11237422, DOI: 10.1128/mbio.00829-24.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsNTM pulmonary diseaseIncreased disease severityNontuberculous mycobacteriaDisease severityBacterial DNAAged animalsAntigen-specific T cellsPulmonary diseaseAssociated with increased disease severityDysregulated macrophage responsePersistence of bacterial DNALack of animal modelsRhesus macaquesSingle-cell RNA sequencingNontuberculous mycobacterial infectionsImmune cell infiltrationRhesus macaque modelBacterial loadAged rhesus macaquesTesting novel therapeuticsRight caudal lobeLower respiratory microbiomeYears of ageMAH infectionMicrobial communitiesChest Intensive Care Unit Imaging Pearls and Pitfalls
Villasana-Gomez G, Toussie D, Kaufman B, Stojanovska J, Moore W, Azour L, Traube L, Ko J. Chest Intensive Care Unit Imaging Pearls and Pitfalls. Clinics In Chest Medicine 2024, 45: 213-235. PMID: 38816084, DOI: 10.1016/j.ccm.2024.02.001.Peer-Reviewed Original ResearchTransthoracic Echocardiography–Guided Placement of a Pulmonary Artery Catheter in a Patient With a Known Persistent Left but Unknown Absent Right Superior Vena Cava
Leclerc J, Clemes R, Fuss C, Macon C, Schulman P. Transthoracic Echocardiography–Guided Placement of a Pulmonary Artery Catheter in a Patient With a Known Persistent Left but Unknown Absent Right Superior Vena Cava. Circulation Cardiovascular Imaging 2024, 17: e016301. PMID: 38469718, DOI: 10.1161/circimaging.123.016301.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and Concepts
2023
Chest Wall Anomaly Presenting as Pulmonary Nodule
Ely S, Van Udelsman B, Bader A, Woodard G. Chest Wall Anomaly Presenting as Pulmonary Nodule. Annals Of Thoracic Surgery Short Reports 2023, 2: 88-90. PMID: 39790260, PMCID: PMC11708574, DOI: 10.1016/j.atssr.2023.11.021.Peer-Reviewed Original ResearchFilamin C-associated Cardiomyopathy on Cardiac MR Images.
Weller S, Bartz-Overman C, Fuss C, Wu E. Filamin C-associated Cardiomyopathy on Cardiac MR Images. Radiology Cardiothoracic Imaging 2023, 5: e230165. PMID: 38166338, PMCID: PMC11163239, DOI: 10.1148/ryct.230165.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsImpact of the COVID-19 Pandemic on Lung Cancer Screening Processes in a Northeast Tertiary Health Care Network
Udelsman B, Detterbeck F, Tanoue L, Mase V, Boffa D, Blasberg J, Dhanasopon A, Ely S, Mazzarelli L, Bader A, Woodard G. Impact of the COVID-19 Pandemic on Lung Cancer Screening Processes in a Northeast Tertiary Health Care Network. Journal Of Computer Assisted Tomography 2023, 48: 222-225. PMID: 37832536, DOI: 10.1097/rct.0000000000001549.Peer-Reviewed Original ResearchAltmetricConceptsHealth care networkLung cancer screening processLung cancer screening programsCare networkCancer screening programsCoronavirus disease 2019 (COVID-19) pandemicComputed tomography scanCOVID-19 hospitalizationCOVID-19 surgeCancer screening processDisease 2019 pandemicLung cancer diagnosisHealth care systemAverage hospitalizationRadiology databaseLung cancerTomography scanScreening programCare systemCancer diagnosisMonthsHospitalizationCOVID-19COVID-19 pandemicPandemicBrief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans
Woodard G, Udelsman B, Prince S, Blasberg J, Dhanasopon A, Gange C, Traube L, Mase V, Boffa D, Detterbeck F, Bader A. Brief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans. JTO Clinical And Research Reports 2023, 4: 100583. PMID: 38074773, PMCID: PMC10709040, DOI: 10.1016/j.jtocrr.2023.100583.Peer-Reviewed Original ResearchCitationsAltmetricConceptsGround-glass nodulesChest CT scanCT scanLung lesionsHealth systemLarge academic health systemAcademic health systemCross-sectional imagingRadiographic findingsPhysician consultationChest CTDatabase reviewTomography scanRadiographic lesionsAge groupsLesionsStudy periodLung nodulesOutpatient CTRadiology reportsAdult chestCTScansChestNodulesImaging Acute and Chronic Cardiac Complications of COVID-19 and after COVID-19 Vaccination.
Sánchez Tijmes F, Marschner C, de Matos J, Urzua Fresno C, Gutiérrez Chacoff J, Thavendiranathan P, Fuss C, Hanneman K. Imaging Acute and Chronic Cardiac Complications of COVID-19 and after COVID-19 Vaccination. RadioGraphics 2023, 43: e230044. PMID: 37616171, DOI: 10.1148/rg.230044.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsLate gadolinium enhancementGadolinium enhancementCardiac MRICOVID-19 vaccinePattern of late gadolinium enhancementCardiac complications of COVID-19MRNA-based COVID-19 vaccinesPresence of cardiovascular diseaseStress-induced cardiomyopathyMultimodality cardiac imagingBasal inferolateral wallMinority of patientsPersistent cardiac symptomsAdverse cardiovascular eventsComplications of COVID-19Chronic cardiac complicationsManifestations of COVID-19Potential mechanisms of injuryMechanism of injuryCardiovascular manifestations of COVID-19Messenger ribonucleic acidAcute COVID-19Cardiac symptomsCardiovascular manifestationsImaging findingsStandardized medical terminology for cardiac computed tomography 2023 update- commentary by North American Society of Cardiovascular Imaging (NASCI)
Rai A, Allen B, Fuss C, Dennie C, Hanneman K. Standardized medical terminology for cardiac computed tomography 2023 update- commentary by North American Society of Cardiovascular Imaging (NASCI). The International Journal Of Cardiovascular Imaging 2023, 39: 2255-2257. PMID: 37589871, DOI: 10.1007/s10554-023-02922-x.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsCardiothoracic complications of immune checkpoint inhibitors
Gosangi B, Wang Y, Rubinowitz A, Kwan J, Traube L, Gange C, Bader A. Cardiothoracic complications of immune checkpoint inhibitors. Clinical Imaging 2023, 102: 98-108. PMID: 37659356, DOI: 10.1016/j.clinimag.2023.08.001.Peer-Reviewed Educational MaterialsCitationsAltmetricMeSH Keywords and ConceptsConceptsImmune checkpoint inhibitorsICI therapyCheckpoint inhibitorsOverall survivalTumor responseAdverse effectsDevelopment of irAEsNovel adverse effectsImproved overall survivalOverall patient outcomesICI administrationHematologic malignanciesPatient outcomesSolid tumorsIrAEsCancer treatmentGreater mortalityComplicationsTherapySurvivalInhibitorsMyocarditisPneumonitisPatientsMalignancyPACS-integrated machine learning breast density classifier: clinical validation
Lewin J, Schoenherr S, Seebass M, Lin M, Philpotts L, Etesami M, Butler R, Durand M, Heller S, Heacock L, Moy L, Tocino I, Westerhoff M. PACS-integrated machine learning breast density classifier: clinical validation. Clinical Imaging 2023, 101: 200-205. PMID: 37421715, DOI: 10.1016/j.clinimag.2023.06.023.Peer-Reviewed Original ResearchCitationsAltmetricOpen-Label Trial of Amikacin Liposome Inhalation Suspension in Mycobacterium abscessus Lung Disease
Siegel S, Griffith D, Philley J, Brown-Elliott B, Brunton A, Sullivan P, Fuss C, Strnad L, Wallace R, Winthrop K. Open-Label Trial of Amikacin Liposome Inhalation Suspension in Mycobacterium abscessus Lung Disease. CHEST Journal 2023, 164: 846-859. PMID: 37419144, PMCID: PMC10645596, DOI: 10.1016/j.chest.2023.05.036.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAmikacin liposome inhalation suspensionAmikacin resistanceCulture conversionInhalation suspensionMycobacterium abscessus lung diseasePresence of macrolide resistanceEnd pointsMicrobiological end pointsMonthly sputum culturesSputum culture conversionTreatment-refractory diseaseOpen-label protocolSecondary end pointsOpen-label trialCohort of patientsCavitary diseaseSputum culturePretreatment isolatesM abscessusOpen-labelOral antimicrobialsParenteral antibioticsCompanion therapyMacrolide resistanceMultidrug therapyQuantitative cardiovascular magnetic resonance findings and clinical risk factors predict cardiovascular outcomes in breast cancer patients
Kwan J, Arbune A, Henry M, Hu R, Wei W, Nguyen V, Lee S, Lopez-Mattei J, Guha A, Huber S, Bader A, Meadows J, Sinusas A, Mojibian H, Peters D, Lustberg M, Hull S, Baldassarre L. Quantitative cardiovascular magnetic resonance findings and clinical risk factors predict cardiovascular outcomes in breast cancer patients. PLOS ONE 2023, 18: e0286364. PMID: 37252927, PMCID: PMC10228774, DOI: 10.1371/journal.pone.0286364.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBreast cancer patientsSystolic heart failureCardiovascular outcomesCancer patientsHeart failureValvular diseaseStrain abnormalitiesLeft ventricular ejection fraction reductionCancer treatment-related cardiotoxicityCardiovascular magnetic resonance findingsVentricular ejection fraction reductionYale-New Haven HospitalEjection fraction reductionTreatment-related cardiotoxicityAdverse cardiovascular outcomesClinical risk factorsNormal LV functionGlobal longitudinal strainIschemic heart diseaseMagnetic resonance findingsRisk regression modelsNew Haven HospitalSubclinical cardiotoxicityDiastolic dysfunctionStatin usePP01.12 Increasing Diagnosis of Ground Glass Nodules and Semi-Solid Lung Lesions on Chest CT Scans over the Past Decade
Woodard G, Tanoue L, Detterbeck F, Boffa D, Mase V, Blasberg J, Dhanasopon A, Gosangi B, Traube L, Bader A. PP01.12 Increasing Diagnosis of Ground Glass Nodules and Semi-Solid Lung Lesions on Chest CT Scans over the Past Decade. Journal Of Thoracic Oncology 2023, 18: e15. DOI: 10.1016/j.jtho.2022.09.038.Peer-Reviewed Original ResearchImaging Findings on Head Computed Tomography Scans in Victims of Intimate Partner Violence
Watane G, Tang A, Thomas R, Park H, Gujrathi R, Gosangi B, Khurana B. Imaging Findings on Head Computed Tomography Scans in Victims of Intimate Partner Violence. Journal Of Computer Assisted Tomography 2023, 47: 307-314. PMID: 36790916, DOI: 10.1097/rct.0000000000001427.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSoft tissue injuriesHead CTInjury visitsIntimate partner violenceTissue injurySubsequent injuryHead computed tomography (CT) scanLeft-sided injuriesInstitutional review board-approved retrospective analysisTime of injurySoft-tissue swellingComputed tomography scanConcomitant injuriesBilateral injuryRadiological findingsImaging findingsStudy cohortSubdural hematomaUnique patientsInjury patternsMean ageCommon manifestationHead injuryInjury typePrior injury