2025
Neuropsychiatric and laboratory outcomes of hepatitis C treatment in an early-treated HIV cohort in Thailand
Ocampo F, Sacdalan C, Pinyakorn S, Paudel M, Wansom T, Poltubtim N, Sriplienchan S, Phanuphak N, Paul R, Hsu D, Colby D, Trautmann L, Spudich S, Chan P. Neuropsychiatric and laboratory outcomes of hepatitis C treatment in an early-treated HIV cohort in Thailand. AIDS Research And Therapy 2025, 22: 20. PMID: 39972347, PMCID: PMC11841302, DOI: 10.1186/s12981-025-00707-x.Peer-Reviewed Original ResearchConceptsWeeks of antiretroviral therapyAcute HIV infectionT-cell countsT cell ratioAntiretroviral therapyPatient Health Questionnaire-9HCV seroconversionDAA treatmentCD4 + and CD8 + T cell countsCD4+ /CD8+ T-cell ratioCD8+ T cell countsDirect-acting antiviral (DAA) therapyAlanine transaminaseCD4+ /CD8+ ratioAspartate transferaseIntravenous drug useEarly HCV infectionSexually transmitted infectionsFollow-up visitPatient Health Questionnaire-9 scoresBackgroundHepatitis C virusHepatitis C treatmentHIV RNAVirological responseDAA therapyThe REpeated ASSEssment of SurvivorS in intracerebral haemorrhage: protocol for a multicentre, prospective observational study
Ziai W, Woo D, Sansing L, Hanley D, Ostapkovich N, Triene K, Gilkerson L, Thompson R, Walborn N, Lane K, McBee N, Langefeld C, Howard T, Vagal A, Flaherty M, Consortium F. The REpeated ASSEssment of SurvivorS in intracerebral haemorrhage: protocol for a multicentre, prospective observational study. BMJ Open 2025, 15: e094322. PMID: 39915023, PMCID: PMC11800296, DOI: 10.1136/bmjopen-2024-094322.Peer-Reviewed Original ResearchMeSH KeywordsAgedCerebral HemorrhageCognitive DysfunctionFemaleHumansMaleMulticenter Studies as TopicNeuropsychological TestsObservational Studies as TopicProspective StudiesSurvivorsConceptsMinimally invasive surgeryIntracerebral haemorrhageInvasive surgeryNon-surgical standard of careProspective observational studySpontaneous intracerebral haemorrhageStandard of careRepeated assessmentsCognitive declineICH volumeInstitutional review boardHaematoma volumeMISTIE IIITreated patientsInflammatory stateTreatment strategiesEthnic/Racial VariationsRt-PAAssessment of survivorsObservational studyRate of cognitive declineUniversity Institutional Review BoardHaemorrhageReview boardPeer-reviewed journalsEarly-life cognitively stimulating activities and late-life cognitive function in the St. Louis Baby Tooth Later Life Health Study
Roberts A, Qiu X, McAlaine K, Germine L, Rotem R, Weisskopf M. Early-life cognitively stimulating activities and late-life cognitive function in the St. Louis Baby Tooth Later Life Health Study. Scientific Reports 2025, 15: 2105. PMID: 39814743, PMCID: PMC11736041, DOI: 10.1038/s41598-024-79083-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAgedAttentionChildCognitionFemaleHumansMaleMemory, Short-TermMiddle AgedNeuropsychological TestsRetrospective StudiesConceptsCognitively stimulating activitiesVisual short-term memoryCognitive functionWorking memoryShort-term memoryProcessing speedTests of crystallized intelligenceAssociated with specific cognitive domainsSpecific cognitive domainsVisual working memoryAssociated with higher cognitive functionOverall cognitive functionHigher cognitive functionsAssociated with overall cognitionLate-life cognitive functionAssociated with higher cognitive scoresCognitive controlEpisodic memoryVerbal reasoningCognitive domainsHigher cognitive scoresSustained attentionAssociated with activationOverall cognitionCognitive tests
2024
Neuroimaging Correlates of the NIH-Toolbox-Driven Cognitive Metrics in Children
Acosta-Rodriguez H, Yuan C, Bobba P, Stephan A, Zeevi T, Malhotra A, Tran A, Kaltenhauser S, Payabvash S. Neuroimaging Correlates of the NIH-Toolbox-Driven Cognitive Metrics in Children. Journal Of Integrative Neuroscience 2024, 23: 217. PMID: 39735971, PMCID: PMC11851640, DOI: 10.31083/j.jin2312217.Peer-Reviewed Original ResearchConceptsCognitive composite scoreAdolescent Brain Cognitive DevelopmentFluid cognition composite scoresStructural magnetic resonance imagingComposite scoreDiffusion tensor imagingNeuroimaging correlatesCognitive functionRs-fMRINational Institutes of Health (NIH) Toolbox Cognition BatteryCognitive scoresMicrostructural integrityResting-state functional connectivityCrystallized cognition composite scoreCortical surface areaTotal cognitive scoreWM microstructural integrityCognitive batteryCrystallized cognitionNeuroanatomical correlatesWhite matterCognitive performanceNeuroimaging metricsFunctional connectivityNeuroimaging dataA professional musician with progressive visuospatial concerns: a case study and review of musical alexia
Ficek-Tani B, Tun S, Frolov A, Sharp E, Fredericks C. A professional musician with progressive visuospatial concerns: a case study and review of musical alexia. Neurocase 2024, 30: 214-225. PMID: 39655794, DOI: 10.1080/13554794.2024.2438413.Peer-Reviewed Original ResearchMemory-related brain potentials for visual objects in early AD show impairment and compensatory mechanisms
Xia J, Kutas M, Salmon D, Stoermann A, Rigatuso S, Farias S, Edland S, Brewer J, Olichney J. Memory-related brain potentials for visual objects in early AD show impairment and compensatory mechanisms. Cerebral Cortex 2024, 34: bhae398. PMID: 39390709, DOI: 10.1093/cercor/bhae398.Peer-Reviewed Original ResearchConceptsEvent-related brain potentialsAmnestic mild cognitive impairmentHippocampal occupancyBrain potentialsMemory abilityNegative ERP effectExecutive function abilitiesVisual memory abilityImpaired episodic memoryVerbal memory abilitiesAlzheimer's diseaseInvestigate neural mechanismsObject recognition taskVisual object recognitionVisual object recognition taskCognitively unimpaired participantsMild cognitive impairmentERP effectsNeuropsychological measuresExecutive functionEpisodic memoryHippocampal functionCompensatory mechanismsVisual memoryNeural mechanismsNormative data for verbal fluency and naming tests in Spanish-speaking adults in the United States
Olabarrieta-Landa L, Rivera D, Xia B, Moreno O, Usuga D, Valdés G, Lopez E, Rodriguez M, Carrión C, Lequerica A, Drago C, García P, Rivera P, Perrin P, Arango-Lasprilla J. Normative data for verbal fluency and naming tests in Spanish-speaking adults in the United States. Neurorehabilitation 2024, 55: 195-208. PMID: 39213096, DOI: 10.3233/nre-240087.Peer-Reviewed Original ResearchConceptsBoston Naming TestVerbal fluency testSemantic verbal fluency testSpanish-speaking adultsFluency testNaming TestSpanish proficiencyNormative dataSpanish-speaking populationLinguistic deficitsVerbal fluencyNeuropsychological NormsTest performanceSpanish speakersTest scoresU.S. participantsPhonemeProficiencyEducational interactionCultural variablesSignificant interactionAdultsImprove accuracy of diagnosisNeurodegenerative disordersAcculturationA preliminary examination of the TOMM2 in a sample of Spanish speakers in the United States
Usuga D, Ayearst L, Rivera D, Krch D, Perrin P, Carrión C, Valdés G, Loro D, Rodriguez M, Munoz G, Drago C, García P, Rivera P, Arango-Lasprilla J. A preliminary examination of the TOMM2 in a sample of Spanish speakers in the United States. Neurorehabilitation 2024, 55: 235-242. PMID: 39240592, DOI: 10.3233/nre-240085.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedFemaleHispanic or LatinoHumansMaleMiddle AgedNeuropsychological TestsReference ValuesUnited StatesYoung AdultConceptsNormative dataPerformance validity measuresSpanish speakersItem-level analysesCognitively healthy adultsRecognition trialsNormative samplePsychiatric disordersTOMMCutoff scoreSpanish versionHispanic individualsDescriptive normsU.S. METHODSValidity measuresCultural appropriatenessHealthy adultsDescriptive analysisTrial 1ScoresItemsSpeakersTrial 2United StatesCognitionExecutive function tests: Normative data for Spanish-speaking adults in the United States
Usuga D, Rivera D, Xia B, Carrión C, Valdés G, Moreno O, Rodriguez M, Krch D, Wongserbchart W, Drago C, García P, Rivera P, Olabarrieta-Landa L, Perrin P, Arango-Lasprilla J. Executive function tests: Normative data for Spanish-speaking adults in the United States. Neurorehabilitation 2024, 55: 209-221. PMID: 39240593, DOI: 10.3233/nre-240088.Peer-Reviewed Original ResearchConceptsNormative dataSCWT performanceSpanish-speaking adultsSpanish-speaking HispanicsExecutive function testsCognitive test performanceImpact of acculturationSpanish-speaking populationOlder adultsU.S. METHODSEducational attainmentFactors influencing performanceExecutive dysfunctionNeuropsychological assessmentAcculturation levelSCWT scoresU.S. statesDiverse populationsU.S. residentsSociocultural factorsNormative data for tests of visuo-spatial, visuo-constructional skills, and visual memory for Spanish-speaking adults in the United States
Valdés G, Rivera D, Olabarrieta-Landa L, Carrión C, Lequerica A, Maltez F, Rodriguez M, Dini M, Munoz G, Usuga D, Drago C, García P, Rivera P, Perrin P, Arango-Lasprilla J. Normative data for tests of visuo-spatial, visuo-constructional skills, and visual memory for Spanish-speaking adults in the United States. Neurorehabilitation 2024, 55: 223-233. PMID: 39302388, DOI: 10.3233/nre-240089.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedFemaleHispanic or LatinoHumansMaleMemoryMiddle AgedNeuropsychological TestsReference ValuesSpace PerceptionUnited StatesVisual PerceptionYoung AdultConceptsRey-Osterrieth Complex Figure TestClock Drawing TestNormative dataTests of visuo-spatialPractice of neuropsychologyComplex Figure TestVisuo-constructive abilitiesVisuo-constructive impairmentCognitively healthy adultsVisuo-constructive skillsPredictor of performanceSpanish-speaking adultsLanguage proficiencyCognitive batteryVisuo-spatialVisuospatial learningExecutive difficultiesBilingual abilitiesConstructional praxisFigures TestVisual memoryMemory recallRecall abilityAcculturation variablesSpanish language proficiencyWHO-UCLA auditory verbal learning test: Normative data for Spanish-speaking adults in the United States
Arango-Lasprilla J, Rivera D, Rodriguez M, Christ B, Moreno O, Usuga D, Olabarrieta-Landa L, Perrin P, Carrión C, Valdés G, Krch D, Amaya A, Drago C, García P, Rivera P. WHO-UCLA auditory verbal learning test: Normative data for Spanish-speaking adults in the United States. Neurorehabilitation 2024, 55: 183-193. PMID: 39302389, DOI: 10.3233/nre-240090.Peer-Reviewed Original ResearchConceptsWHO-UCLA AVLTSpanish-speaking HispanicsNormative dataAuditory Verbal Learning TestComprehensive neuropsychological batteryVerbal Learning TestMeasures of learningEvaluate cognitive functionSpanish-speaking individualsSpanish-speaking adultsDuration of U.S. residenceNeuropsychological batteryLearning TestNeuropsychological assessmentDelayed recallAssess cognitionCognitive functionLanguage proficiencyLinguistic factorsSpanish proficiencyTest performanceU.S. METHODSCultural nuancesDiverse culturesHispanicsAttention and processing speed tests: Normative data for Spanish-speaking adults in the United States
Carrión C, Rivera D, Forte A, Olabarrieta-Landa L, Moreno O, Usuga D, Valdés G, López M, Rodriguez M, Lequerica A, Drago C, García P, Rivera P, Perrin P, Arango-Lasprilla J. Attention and processing speed tests: Normative data for Spanish-speaking adults in the United States. Neurorehabilitation 2024, 55: 169-182. PMID: 39331117, DOI: 10.3233/nre-240086.Peer-Reviewed Original ResearchConceptsBrief Test of AttentionSymbol Digit Modalities TestTrail-Making TestNormative dataSpanish speakersComprehensive neuropsychological batteryProcessing speed measuresProcessing speed testsMeasures of attentionTests of attentionProcessing speed performanceSociodemographic factorsSpanish-speaking individualsSpanish-speaking adultsSpanish-speaking populationNeuropsychological batteryTrail-MakingSymbol-DigitInfluence attentionTMT-BTMT-ABrief testCognitive testsProcessing speedLinguistic factorsObjective and subjective experiences of childhood maltreatment and their relationships with cognitive deficits: a cohort study in the USA
Danese A, Widom C. Objective and subjective experiences of childhood maltreatment and their relationships with cognitive deficits: a cohort study in the USA. The Lancet Psychiatry 2024, 11: 720-730. PMID: 39147460, DOI: 10.1016/s2215-0366(24)00224-4.Peer-Reviewed Original ResearchConceptsMeasures of childhood maltreatmentExperiences of childhood maltreatmentMeasures of maltreatmentChildhood maltreatmentCognitive deficitsRetrospective reports of childhood maltreatmentReports of childhood maltreatmentSelf-reportNational Institute of Mental HealthInstitute of Mental HealthPervasive cognitive deficitsNon-verbal intelligenceMeasures of neglectRetrospective self-reportsVerbal intelligenceAutobiographical memoryExecutive functionMaltreated childrenCognitive abilitiesPsychopathologyCognitive testsCognitive functionGroup differencesProcessing speedRetrospective reportsSleep apnea in schizophrenia: Estimating prevalence and impact on cognition
Ghazikhanian S, Surti T. Sleep apnea in schizophrenia: Estimating prevalence and impact on cognition. Journal Of Psychiatric Research 2024, 177: 330-337. PMID: 39068777, DOI: 10.1016/j.jpsychires.2024.07.028.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCognition DisordersComorbidityFemaleHumansMaleMiddle AgedNeuropsychological TestsPrevalenceSchizophreniaSchizophrenic PsychologySleep Apnea, ObstructiveVeteransConceptsObstructive sleep apneaPrevalence of obstructive sleep apneaCognitive deficits of schizophreniaWorking memory test scoresDeficits of schizophreniaSleep apneaImpaired cognitive domainsSpeed of processingDisabling cognitive deficitsMemory test scoresHigher cognitive capacityFunctional capacity performanceAssociated with lower speedsVerbal learningCognitive domainsCompromised cognitionSchizophreniaRisk of obstructive sleep apneaEffects of sleep apneaCognitive capacityCognitive impairmentPredicting obstructive sleep apneaSelf-reportMedical illnessFunctional capacity assessmentAsian Cohort for Alzheimer Disease (ACAD) Pilot Study
Peavy G, Võ N, Revta C, Lu A, Lupo J, Nam P, Nguyễn K, Wang L, Feldman H. Asian Cohort for Alzheimer Disease (ACAD) Pilot Study. Alzheimer Disease & Associated Disorders 2024, 38: 277-284. PMID: 39177172, PMCID: PMC11340683, DOI: 10.1097/wad.0000000000000631.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAlzheimer DiseaseAsianCognitive DysfunctionCohort StudiesFemaleHumansMaleMiddle AgedNeuropsychological TestsPilot ProjectsRisk FactorsVietnamConceptsSubjective cognitive complaintsOlder Vietnamese AmericansVascular risk factorsMild cognitive impairmentVietnamese AmericansRisk factorsMeasuring subjective cognitive complaintsPilot studyCommunity advisory boardNongenetic risk factorsCommunity-based researchAD risk factorsAlzheimer's diseaseDepressive symptomsConsensus teamCognitive complaintsBilingual/bicultural staffAD riskAssessment toolAdvisory boardVietnamese communityExploratory analysisCognitive difficultiesCognitive impairmentParticipantsCognitive performance in functional seizures compared with epilepsy and healthy controls: a systematic review and meta analysis
Van Patten R, Austin T, Cotton E, Chan L, Bellone J, Mordecai K, Altalib H, Correia S, Twamley E, Jones R, Sawyer K, LaFrance W. Cognitive performance in functional seizures compared with epilepsy and healthy controls: a systematic review and meta analysis. The Lancet Psychiatry 2024, 11: 516-525. PMID: 38879275, DOI: 10.1016/s2215-0366(24)00132-9.Peer-Reviewed Original ResearchConceptsRisk of biasSystematic reviewHealthy comparisonGlobal cognitionMeta-analysisCognitive performanceDepartment of Veterans AffairsVeterans Health AdministrationFunctional seizuresIndividual studiesCognitive domainsModerate effect sizeProportion of womenNewcastle-Ottawa ScaleLeft temporal lobe epilepsyWeb of ScienceCognitive test dataWidespread cognitive impairmentVeterans AffairsEffects of multiple covariatesHealth AdministrationGrey literatureSeizure groupNewcastle-OttawaInclusion criteriaLocus coeruleus integrity and left frontoparietal connectivity provide resilience against attentional decline in preclinical alzheimer’s disease
Pahl J, Prokopiou P, Bueichekú E, Schultz A, Papp K, Farrell M, Rentz D, Sperling R, Johnson K, Jacobs H. Locus coeruleus integrity and left frontoparietal connectivity provide resilience against attentional decline in preclinical alzheimer’s disease. Alzheimer's Research & Therapy 2024, 16: 119. PMID: 38822365, PMCID: PMC11140954, DOI: 10.1186/s13195-024-01485-w.Peer-Reviewed Original ResearchConceptsDigit Symbol Substitution TestLC integrityLocus coeruleusAttentional declineCognitive declineDigit-symbol substitution test performanceHarvard Aging Brain StudyResting-state functional MRILocus coeruleus integrityNetwork functional connectivityAlzheimer's diseaseAging Brain StudyPreclinical Alzheimer's diseaseCognitive follow-upYears of educationNeural reserveNeural correlatesAttentional performanceAttention deficitMixed effects analysisCortical target regionsSubstitution TestCognitive changesFrontoparietal connectivityFunctional MRIAssociation Between Hypertensive Disorders of Pregnancy and Interval Neurocognitive Decline
Elfassy T, Kulandavelu S, Dodds L, Mesa R, Rundek T, Sharashidze V, Paidas M, Daviglus M, Kominiarek M, Stickel A, Perreira K, Kobayashi M, Garcia T, Isasi C, Lipton R, González H. Association Between Hypertensive Disorders of Pregnancy and Interval Neurocognitive Decline. Obstetrics And Gynecology 2024, 143: 785-793. PMID: 38574370, PMCID: PMC11098694, DOI: 10.1097/aog.0000000000005571.Peer-Reviewed Original ResearchConceptsCognitive declineHypertensive disorders of pregnancyNeurocognitive assessmentDisorders of pregnancyAssociated with decreased processing speedBrief-Spanish English Verbal Learning TestSpanish English Verbal Learning TestDigit symbol substitution scoresVerbal Learning TestDigit symbol substitutionNeurocognitive declineAssociated with cognitive declineHypertensive disordersGestational hypertensionFollow-up timeFunction of cognitionWord fluencyExecutive functionNeurocognitive differencesLearning TestCognitive domainsSymbol substitutionCognitive functionProcessing speedSelf-reportAltered cerebral white matter network topology and cognition in children with obstructive sleep apnea
Chen F, Fu Y, Tang B, Tao B, Wang Y, Huang Y, Chen T, Yu C, Jiang C, Lui S, Cai X, Lu Y, Yan Z. Altered cerebral white matter network topology and cognition in children with obstructive sleep apnea. Sleep Medicine 2024, 118: 63-70. PMID: 38613858, DOI: 10.1016/j.sleep.2024.03.038.Peer-Reviewed Original ResearchMeSH KeywordsBrainChildCognitionCognitive DysfunctionFemaleHumansMagnetic Resonance ImagingMaleNeuropsychological TestsPolysomnographySleep Apnea, ObstructiveWhite MatterConceptsObstructive apnea-hypopnea indexWhite matter networksVerbal Comprehension IndexNon-OSA childrenEvidence of impaired cognitive functionRight temporal poleSuperior temporal gyrusImpaired cognitive functionBrain white matter networkHierarchical linear regressionApnea-hypopnea indexObstructive sleep apneaNeuroimaging evidenceTemporal gyrusTemporal poleBrain regionsCognitive testsCognitive functionMediation analysisTemporal lobeCognitive impairmentChild's brainNetwork propertiesSleep apneaComprehensive indexNeuropsychological Assessments of Cognitive Impairment in Major Depressive Disorder: A Systematic Review and Meta-Analysis with Meta-Regression
Rhee T, Shim S, Manning K, Tennen H, Kaster T, d’Andrea G, Forester B, Nierenberg A, McIntyre R, Steffens D. Neuropsychological Assessments of Cognitive Impairment in Major Depressive Disorder: A Systematic Review and Meta-Analysis with Meta-Regression. Psychotherapy And Psychosomatics 2024, 93: 8-23. PMID: 38272009, PMCID: PMC10880806, DOI: 10.1159/000535665.Peer-Reviewed Original ResearchConceptsCambridge Neuropsychological Test Automated BatteryAssessment of cognitive impairmentCognitive deficitsCognitive impairmentDepressive disorderNeuropsychological assessmentRemediation of cognitive impairmentAlleviation of depressive symptomsHealthy controlsEffect sizeTreatment-resistant depressionMajor depressive disorderDiagnosis of MDDModerate cognitive deficitsUnmedicated patientsHedges g standardized mean differencesDepressive symptomsMDDCompared to healthy controlsCognitive dysfunctionStandardized effect sizeStandardized diagnostic criteriaQuantify effect sizesDeficitsFixed- or random-effects model
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