2024
Electrochemotherapy in the Locoregional Treatment of Metastatic Colorectal Liver Metastases: A Systematic Review
Barbieri P, Posa A, Lancellotta V, Madoff D, Maresca A, Cornacchione P, Tagliaferri L, Iezzi R. Electrochemotherapy in the Locoregional Treatment of Metastatic Colorectal Liver Metastases: A Systematic Review. Current Oncology 2024, 31: 7403-7413. PMID: 39590176, PMCID: PMC11592455, DOI: 10.3390/curroncol31110546.Peer-Reviewed Original ResearchConceptsCRC liver metastasesLiver metastasesColorectal cancerComplete responseOverall survivalProgressive diseaseInclusion criteriaResection of CRC liver metastasesTreatment of CRC liver metastasisColorectal cancer liver metastasesSystematic searches of PubMedFrequent liver metastasesMedian overall survivalSecondary liver cancerFollow-up durationColorectal Liver MetastasesMultiple risk factorsCancer-related mortalitySearch of PubMedECT-related complicationsEvidence qualityLocoregional treatmentSurgical resectionIdentified articlesGRADE approach
2016
Irreversible Electroporation in Interventional Oncology: Where We Stand and Where We Go
Savic LJ, Chapiro J, Hamm B, Gebauer B, Collettini F. Irreversible Electroporation in Interventional Oncology: Where We Stand and Where We Go. RöFo 2016, 188: 735-745. PMID: 27074423, DOI: 10.1055/s-0042-104203.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesElectrochemotherapyEvidence-Based MedicineHumansNeoplasmsPostoperative ComplicationsTreatment OutcomeConceptsClinical evidenceIrreversible electroporationInterventional oncologyPancreatic irreversible electroporationSite-specific complicationsAvailable clinical evidenceUse of IRELimited clinical evidenceFavorable safety profileTolerable morbidityOncologic efficacyPreclinical findingsBile ductSafety profileNeurovascular bundleInvasive treatmentLung parenchymaAblation therapySolid tumorsClinical settingTumor ablation therapyHeat sink effectNon-thermal fashionLiverTumor ablation
2009
Electroporating Fields Target Oxidatively Damaged Areas in the Cell Membrane
Vernier PT, Levine ZA, Wu YH, Joubert V, Ziegler MJ, Mir LM, Tieleman DP. Electroporating Fields Target Oxidatively Damaged Areas in the Cell Membrane. PLOS ONE 2009, 4: e7966. PMID: 19956595, PMCID: PMC2779261, DOI: 10.1371/journal.pone.0007966.Peer-Reviewed Original ResearchConceptsLiving cellsComplex biomolecular assembliesPlasma membraneMolecular basisGenetic materialMembrane componentsCell membraneBiomolecular assembliesPermeabilization procedureModel membranesElectroporation protocolReversible electropermeabilizationOxidative stressElectropermeabilizationMembraneCell suspensionsDetailed understandingMolecular dynamics simulationsGene therapyCellsConsiderable knowledgeAssemblyDynamics simulationsPharmaceutical agents
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply