2024
Risk of harm to people with haemophilia from the 2023 WHO Essential Medicines List
Pierce G, O'Mahony B, Kaczmarek R, Skinner M, Makris M, Peyvandi F, Srivastava A, Hermans C, World Federation of Hemophilia Coagulation Products Supply S, Crato M, Dunn A, Gouider E, Mahlangu J, Page D, Pipe S, Recht M, Sannie T, Schaefer N, Schlenkrich U, Garrido C. Risk of harm to people with haemophilia from the 2023 WHO Essential Medicines List. The Lancet Haematology 2024, 11: e638-e640. PMID: 39116903, DOI: 10.1016/s2352-3026(24)00223-0.Peer-Reviewed Original ResearchWHO treatment guideline for mental disorders
Leichsenring F, Abbass A, Fonagy P, Levy K, Lilliengren P, Luyten P, Midgley N, Milrod B, Steinert C. WHO treatment guideline for mental disorders. The Lancet Psychiatry 2024, 11: 676-677. PMID: 39067469, DOI: 10.1016/s2215-0366(24)00169-x.Peer-Reviewed Original ResearchRadiologic-Pathologic Correlation of Cardiac Tumors: Updated 2021 WHO Tumor Classification.
Lorca M, Chen I, Jew G, Furlani A, Puri S, Haramati L, Chaturvedi A, Velez M, Chaturvedi A. Radiologic-Pathologic Correlation of Cardiac Tumors: Updated 2021 WHO Tumor Classification. RadioGraphics 2024, 44: e230126. PMID: 38722782, DOI: 10.1148/rg.230126.Peer-Reviewed Educational MaterialsMeSH KeywordsEchocardiographyHeart NeoplasmsHumansMagnetic Resonance ImagingMultimodal ImagingTomography, X-Ray ComputedWorld Health OrganizationConceptsCardiac tumorsClassification of tumorsCardiac massWorld Health OrganizationCharacterization of cardiac massesWorld Health Organization Classification of TumorsWorld Health Organization tumor classificationWorld Health Organization classificationMalignant cardiac massesPrimary cardiac tumorsPrimary cardiac neoplasmsCardiac metastasisPapillary fibroelastomaThoracoabdominal CTCardiac CTCardiac neoplasmsIntracardiac massesNoncardiac indicationsSurgical managementRadiological investigationsTumor biologyTumor typesCardiac MRIAnatomical variantsTreatment planningThe World Federation of Chiropractic Global Patient Safety Task Force: a call to action
Coleman B, Rubinstein S, Salsbury S, Swain M, Brown R, Pohlman K. The World Federation of Chiropractic Global Patient Safety Task Force: a call to action. Chiropractic & Manual Therapies 2024, 32: 15. PMID: 38741191, PMCID: PMC11092090, DOI: 10.1186/s12998-024-00536-1.Peer-Reviewed Original ResearchMeSH KeywordsAdvisory CommitteesChiropracticGlobal HealthHumansPatient SafetyWorld Health OrganizationConceptsWorld Federation of ChiropracticChiropractic professionSafety Task ForcePatient safetyWorld Health OrganizationTask ForcePatient safety competencyPatient safety culturePatient safety proceduresImprove patient safetyAction planChiropractic careChiropractic communitySafety competenciesWorld FederationFamily engagementSafety cultureClinical interactionsTraining programAction stepsHealth OrganizationHealthcareSystemic obstaclesProfessionChiropracticReductions in World Health Organization Risk Drinking Level Are Associated With Reductions in Alcohol Use Disorder Diagnosis and Criteria: Evidence From an Alcohol Pharmacotherapy Trial
Richards D, Tuchman F, Hallgren K, Kranzler H, Aubin H, O'Malley S, Mann K, Aldridge A, Anton R, Witkiewitz K. Reductions in World Health Organization Risk Drinking Level Are Associated With Reductions in Alcohol Use Disorder Diagnosis and Criteria: Evidence From an Alcohol Pharmacotherapy Trial. Journal Of Addiction Medicine 2024, 18: 418-424. PMID: 38606854, PMCID: PMC11290995, DOI: 10.1097/adm.0000000000001303.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingAlcoholismDelayed-Action PreparationsFemaleHumansMaleMiddle AgedTreatment OutcomeWorld Health OrganizationConceptsWorld Health Organization risk drinking levelsAlcohol use disorderAlcohol use disorder diagnosisAlcohol use disorder criteriaDrinking levelsMini International Neuropsychiatric InterviewSevere alcohol use disorderCurrent alcohol use disorderGabapentin enacarbilRisk drinking levelsMultisite randomized controlled trialAlcohol intervention trialPharmacotherapy trialsAUD diagnosisAUD treatmentNeuropsychiatric InterviewBaseline to endDisorder diagnosisEnd of treatmentFollow-backUse disorderAssess DiagnosticWorld Health OrganizationAssociated with reductionsSecondary data analysisReductions in World Health Organization risk drinking level are associated with improvements in sleep problems among individuals with alcohol use disorder
Garcia C, Richards D, Tuchman F, Hallgren K, Kranzler H, Aubin H, O’Malley S, Mann K, Aldridge A, Hoffman M, Anton R, Witkiewitz K. Reductions in World Health Organization risk drinking level are associated with improvements in sleep problems among individuals with alcohol use disorder. Alcohol And Alcoholism 2024, 59: agae022. PMID: 38606931, PMCID: PMC11010310, DOI: 10.1093/alcalc/agae022.Peer-Reviewed Original ResearchConceptsAlcohol use disorderSleep problemsAssociated with improvementsUse disorderMaintenance of alcohol use disorderDrinking levelsWorld Health Organization risk drinking levelsRisk drinking levelsTimeline Follow-BackSleep problem scoreFewer sleep problemsMonths of treatmentDrinking reductionFollow-backPittsburgh Sleep Quality IndexActive medicationSleep Quality IndexProblem scoresExtended-releaseAlcohol usePlacebo groupSleep disturbanceHarm reduction approachesSleep qualityControlled trials
2023
Evaluation of the diabetes care cascade and compliance with WHO global coverage targets in Iran based on STEPS survey 2021
Azadnajafabad S, Ahmadi N, Rezaei N, Rashidi M, Saeedi Moghaddam S, Mohammadi E, Abbasi-Kangevari M, Naderian M, Ghasemi E, Farzi Y, Kazemi A, Dilmaghani-Marand A, Yoosefi M, Rezaei S, Nasserinejad M, Fattahi N, Rezaei N, Haghshenas R, Foroutan Mehr E, Koolaji S, Razi F, Djalalinia S, Larijani B, Farzadfar F. Evaluation of the diabetes care cascade and compliance with WHO global coverage targets in Iran based on STEPS survey 2021. Scientific Reports 2023, 13: 13528. PMID: 37598214, PMCID: PMC10439917, DOI: 10.1038/s41598-023-39433-7.Peer-Reviewed Original ResearchConceptsCare cascadeSTEPS surveyCoverage targetsDM diagnosisDiabetes care cascadeTreatment coverageSub-optimal careGlycemic controlPrevalence of DMDiabetes mellitusDiabetes awarenessNational prevalenceWorld Health OrganizationControl statusCareGood glycemic controlIranian populationPrediabetesHealth OrganizationGlobal targetsDiabetesPrevalenceSurveyPopulationComplianceWHO ends public health emergency designation for mpox
Carlson C, Katz R. WHO ends public health emergency designation for mpox. The BMJ 2023, 381: p1190. PMID: 37277145, DOI: 10.1136/bmj.p1190.Peer-Reviewed Original ResearchUpdate of pediatric bone tumors—other mesenchymal tumors of bone, hematopoietic neoplasms of bone, and WHO classification of undifferentiated small round cell sarcomas of bone
Wang A, Maloney E, Al-Dasuqi K, Irshaid L, Ahmed A, Haims A, Porrino J. Update of pediatric bone tumors—other mesenchymal tumors of bone, hematopoietic neoplasms of bone, and WHO classification of undifferentiated small round cell sarcomas of bone. Skeletal Radiology 2023, 52: 1443-1463. PMID: 36656343, DOI: 10.1007/s00256-023-04286-8.Peer-Reviewed Original ResearchMeSH KeywordsBone and BonesBone NeoplasmsChildGiant Cell TumorsHematologic NeoplasmsHumansSarcomaSoft Tissue NeoplasmsWorld Health OrganizationConceptsUndifferentiated small round cell sarcomaSmall round cell sarcomasBone tumorsRound cell sarcomasPediatric populationCell sarcomaMesenchymal tumorsHematopoietic neoplasmsWorld Health Organization classificationGiant cell-rich tumorsPediatric bone tumorsOsteogenic tumorsOrganization classificationVascular tumorsNotochordal tumorsTumorsGenetic sequencing techniquesChondrogenic tumorsCertain lesionsSoft tissueBoneSarcomaNeoplasmsSeparate manuscriptDetailed updateRecent Advances in the Classification of Gynecological Tract Tumors: Updates From the 5th Edition of the World Health Organization "Blue Book".
Parkash V, Aisagbonhi O, Riddle N, Siddon A, Panse G, Fadare O. Recent Advances in the Classification of Gynecological Tract Tumors: Updates From the 5th Edition of the World Health Organization "Blue Book". Archives Of Pathology & Laboratory Medicine 2023, 147: 1204-1216. PMID: 36596270, DOI: 10.5858/arpa.2022-0166-ra.Peer-Reviewed Original ResearchConceptsWorld Health Organization classificationOrganization classificationWorld Health OrganizationTract tumorsGynecological tumorsFemale genital tract tumorsHealth OrganizationGenital tract tumorsHuman papillomavirus associationFemale genital tumorsLower genital tractFallopian tube tumorsRoutine clinical practiceGenetic tumor syndromesSite of originGenital tumorsGenital tractDiagnostic criteriaGlandular lesionsClinical practiceTumor syndromeTumorsComprehensive updateSyndromeLesions
2022
Update of pediatric bone tumors—notochordal tumors, chondrogenic tumors, and vascular tumors of the bone
Lee H, Wang A, Cheng R, Moran J, Al-Dasuqi K, Irshaid L, Maloney E, Porrino J. Update of pediatric bone tumors—notochordal tumors, chondrogenic tumors, and vascular tumors of the bone. Skeletal Radiology 2022, 52: 1101-1117. PMID: 36369290, DOI: 10.1007/s00256-022-04235-x.Peer-Reviewed Original ResearchMeSH KeywordsBone NeoplasmsChildDiagnostic ImagingHumansNeoplasms, Connective TissuePrognosisWorld Health OrganizationUpdate of pediatric bone tumors: osteogenic tumors and osteoclastic giant cell-rich tumors
Al-Dasuqi K, Cheng R, Moran J, Irshaid L, Maloney E, Porrino J. Update of pediatric bone tumors: osteogenic tumors and osteoclastic giant cell-rich tumors. Skeletal Radiology 2022, 52: 671-685. PMID: 36326880, DOI: 10.1007/s00256-022-04221-3.Peer-Reviewed Original ResearchMeSH KeywordsBone NeoplasmsChildGiant Cell TumorsGiant CellsHumansPrognosisWorld Health OrganizationSystematic review and meta‐analysis of breastfeeding and later overweight or obesity expands on previous study for World Health Organization
Horta BL, Rollins N, Dias MS, Garcez V, Pérez‐Escamilla R. Systematic review and meta‐analysis of breastfeeding and later overweight or obesity expands on previous study for World Health Organization. Acta Paediatrica 2022, 112: 34-41. PMID: 35727183, DOI: 10.1111/apa.16460.Peer-Reviewed Original ResearchMeSH KeywordsBreast FeedingChildChild, PreschoolHumansInfantOverweightPediatric ObesitySocial ClassWorld Health OrganizationConceptsResidual confoundingWorld Health OrganizationSystematic reviewPublication biasHealth OrganizationSocioeconomic statusOdds of overweightBenefits of breastfeedingRandom-effects modelWeb of ScienceIndependent reviewersPositive confoundingOverweightObesityBreastfeedingConfoundingAssociationReviewStatusPrevious studiesMEDLINEInfantsStudyLILACSPredictors of abstinence, no heavy drinking days, and a 2‐level reduction in World Health Organization drinking levels during treatment for alcohol use disorder in the COMBINE study
Wallach JD, Gueorguieva R, Phan H, Witkiewitz K, Wu R, O'Malley SS. Predictors of abstinence, no heavy drinking days, and a 2‐level reduction in World Health Organization drinking levels during treatment for alcohol use disorder in the COMBINE study. Alcohol Clinical And Experimental Research 2022, 46: 1331-1339. PMID: 35616436, PMCID: PMC9887652, DOI: 10.1111/acer.14877.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol AbstinenceAlcohol DrinkingAlcoholismHumansNaltrexoneTreatment OutcomeWorld Health OrganizationConceptsHeavy drinking daysWeeks of treatmentAlcohol use disorderDependence Scale scoresDrinking daysScale scoreDays abstinentPredictors of abstinenceConsecutive weeksUse disordersDrinking levelsCOMBINE StudyOlder subjectsRandomized placebo-controlled trialPlacebo-controlled trialEfficacy of naltrexoneMultiple patient characteristicsTrials of medicationsBehavioral intervention studyPatient characteristicsFuture trialsBaseline variablesCombined PharmacotherapiesYoung subjectsComplete abstinenceImproved hypertension control at six months using an adapted WHO HEARTS-based implementation strategy at a large urban HIV clinic in Uganda
Muddu M, Semitala FC, Kimera I, Mbuliro M, Ssennyonjo R, Kigozi SP, Katwesigye R, Ayebare F, Namugenyi C, Mugabe F, Mutungi G, Longenecker CT, Katahoire AR, Ssinabulya I, Schwartz JI. Improved hypertension control at six months using an adapted WHO HEARTS-based implementation strategy at a large urban HIV clinic in Uganda. BMC Health Services Research 2022, 22: 699. PMID: 35610717, PMCID: PMC9131679, DOI: 10.1186/s12913-022-08045-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlood PressureFemaleHIV InfectionsHumansHypertensionMaleMiddle AgedUgandaWorld Health OrganizationConceptsLarge urban HIV clinicUrban HIV clinicHTN outcomesHIV clinicHypertension controlViral suppressionHIV outcomesHTN treatmentFurther implementation researchHIV viral suppressionProportion of patientsPre-post studyVaried clinical settingsAdult PLHIVBP controlHTN controlHTN screeningCare cascadeHIV careLifestyle counselingClinic visitsDiastolic BPHIV controlIndependent predictorsSystolic BPComparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk
Denoble AE, Goldstein SA, Wein LE, Grotegut CA, Federspiel JJ. Comparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk. American Heart Journal 2022, 250: 11-22. PMID: 35526569, PMCID: PMC9836743, DOI: 10.1016/j.ahj.2022.04.009.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesFemaleHeart Disease Risk FactorsHumansMorbidityPregnancyRetrospective StudiesRisk FactorsWorld Health OrganizationConceptsSevere maternal morbidityWorld Health Organization classificationDelivery hospitalizationsCardiac diagnosisMaternal morbidityOrganization classificationMaternal cardiovascular riskNationwide Readmissions DatabaseRisk of deathSevere cardiac diseaseWeighted national estimateMWHO classificationDelivery admissionCardiovascular riskPregnant patientsSecondary outcomesPrimary outcomeRetrospective studyYear postpartumPregnancy counselingPrimary exposureMonths postpartumNationwide databaseCardiac diseaseElevated riskThe 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis
Walker T, Miotto P, Köser C, Fowler P, Knaggs J, Iqbal Z, Hunt M, Chindelevitch L, Farhat M, Cirillo D, Comas I, Posey J, Omar S, Peto T, Suresh A, Uplekar S, Laurent S, Colman R, Nathanson C, Zignol M, Walker A, Crook D, Ismail N, Rodwell T, Consortium T, Walker A, Steyn A, Lalvani A, Baulard A, Christoffels A, Mendoza-Ticona A, Trovato A, Skrahina A, Lachapelle A, Brankin A, Piatek A, Cruz A, Koch A, Cabibbe A, Spitaleri A, Brandao A, Chaiprasert A, Suresh A, Barbova A, Van Rie A, Ghodousi A, Bainomugisa A, Mandal A, Roohi A, Javid B, Zhu B, Letcher B, Rodrigues C, Nimmo C, NATHANSON C, Duncan C, Coulter C, Utpatel C, Liu C, Grazian C, Kong C, Köser C, Wilson D, Cirillo D, Matias D, Jorgensen D, Zimenkov D, Chetty D, Moore D, Clifton D, Crook D, van Soolingen D, Liu D, Kohlerschmidt D, Barreira D, Ngcamu D, Lazaro E, Kelly E, Borroni E, Roycroft E, Andre E, Böttger E, Robinson E, Menardo F, Mendes F, Jamieson F, Coll F, Gao G, Kasule G, Rossolini G, Rodger G, Smith E, Meintjes G, Thwaites G, Hoffmann H, Albert H, Cox H, Laurenson I, Comas I, Arandjelovic I, Barilar I, Robledo J, Millard J, Johnston J, Posey J, Andrews J, Knaggs J, Gardy J, Guthrie J, Taylor J, Werngren J, Metcalfe J, Coronel J, Shea J, Carter J, Pinhata J, Kus J, Todt K, Holt K, Nilgiriwala K, Ghisi K, Malone K, Faksri K, Musser K, Joseph L, Rigouts L, Chindelevitch L, Jarrett L, Grandjean L, Ferrazoli L, Rodrigues M, Farhat M, Schito M, Fitzgibbon M, Loembé M, Wijkander M, Ballif M, Rabodoarivelo M, Mihalic M, WILCOX M, Hunt M, ZIGNOL M, Merker M, Egger M, O'Donnell M, Caws M, Wu M, Whitfield M, Inouye M, Mansjö M, Thi M, Joloba M, Kamal S, Okozi N, ISMAIL N, Mistry N, Hoang N, Rakotosamimanana N, Paton N, Rancoita P, Miotto P, Lapierre P, Hall P, Tang P, Claxton P, Wintringer P, Keller P, Thai P, Fowler P, Supply P, Srilohasin P, Suriyaphol P, Rathod P, Kambli P, Groenheit R, Colman R, Ong R, Warren R, Wilkinson R, Diel R, Oliveira R, Khot R, Jou R, Tahseen S, Laurent S, Gharbia S, Kouchaki S, Shah S, Plesnik S, Earle S, Dunstan S, Hoosdally S, Mitarai S, Gagneux S, Omar S, Yao S, Lapierre S, Battaglia S, Niemann S, Pandey S, Uplekar S, Halse T, Cohen T, Cortes T, Prammananan T, Kohl T, Thuong N, Teo T, Peto T, Rodwell T, William T, Walker T, Rogers T, Surve U, Mathys V, Furió V, Cook V, Vijay S, Escuyer V, Dreyer V, Sintchenko V, Saphonn V, Solano W, Lin W, van Gemert W, He W, Yang Y, Zhao Y, Qin Y, Xiao Y, Hasan Z, Iqbal Z, Puyen Z. The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis. The Lancet Microbe 2022, 3: e265-e273. PMID: 35373160, PMCID: PMC7612554, DOI: 10.1016/s2666-5247(21)00301-3.Peer-Reviewed Original ResearchMeSH KeywordsAntitubercular AgentsDrug ResistanceEthambutolMicrobial Sensitivity TestsMutationMycobacterium tuberculosisWorld Health OrganizationConceptsConsistent with susceptibilityAssociated with resistancePhenotypic resistanceDrug susceptibility testingSusceptibility testingPositive predictive valueAssociated with phenotypic resistanceWhole-genome sequencingPrevalence of phenotypic resistanceMolecular diagnosticsDrug susceptibility testing dataUniversal drug susceptibility testingMutations associated with drug resistanceOdds ratioSusceptibility testing dataDrug resistance predictionImplementation of molecular diagnosticsBinary phenotypesPredictive valueGene approachMTBC isolatesUnique mutationsFisher's exact testAnti-tuberculosis drugsGenotype analysisOverview of the 2022 WHO Classification of Neuroendocrine Neoplasms
Rindi G, Mete O, Uccella S, Basturk O, La Rosa S, Brosens L, Ezzat S, de Herder W, Klimstra D, Papotti M, Asa S. Overview of the 2022 WHO Classification of Neuroendocrine Neoplasms. Endocrine Pathology 2022, 33: 115-154. PMID: 35294740, DOI: 10.1007/s12022-022-09708-2.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, NeuroendocrineHumansImmunohistochemistryNeuroendocrine TumorsReceptors, SomatostatinRepressor ProteinsWorld Health OrganizationConceptsNeuroendocrine tumorsNeuroendocrine neoplasmsSomatostatin receptorsWHO classificationNon-neuroendocrineDifferential diagnosisWHO Classification of EndocrineExpression of somatostatin receptorsWHO classification of neuroendocrine neoplasmsG3 neuroendocrine tumorsAssociated with germline mutationsPancreatic neuroendocrine tumorsClassification of neuroendocrine neoplasmsEctopic hormone productionLoss of RbLoss of ATRXSite of originComposite tumorMetastatic lesionsAberrant p53Amphicrine tumorsEpithelial neoplasmsPrecursor lesionsTheranostic biomarkersGermline mutations
2021
Global estimates of paediatric tuberculosis incidence in 2013–19: a mathematical modelling analysis
Yerramsetti S, Cohen T, Atun R, Menzies NA. Global estimates of paediatric tuberculosis incidence in 2013–19: a mathematical modelling analysis. The Lancet Global Health 2021, 10: e207-e215. PMID: 34895517, PMCID: PMC8800006, DOI: 10.1016/s2214-109x(21)00462-9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsBayes TheoremChildChild, PreschoolFemaleGlobal HealthHumansIncidenceInfantMaleModels, TheoreticalRisk FactorsTuberculosisWorld Health OrganizationConceptsPediatric tuberculosisTuberculosis incidenceStudy periodIncident tuberculosis casesTuberculosis incidence rateReporting systemHigh-burden settingsGlobal tuberculosis burdenTuberculosis natural historyPediatric incidenceInfectious exposurePrompt diagnosisSubstantial morbidityTuberculosis burdenTuberculosis casesIncidence rateRisk factorsCase detectionGlobal incidenceProbability of infectionInfected individualsAge groupsNatural historyTuberculosisIncidenceImmunohistochemistry in gynecologic carcinomas: Practical update with diagnostic and clinical considerations based on the 2020 WHO classification of tumors
Buza N. Immunohistochemistry in gynecologic carcinomas: Practical update with diagnostic and clinical considerations based on the 2020 WHO classification of tumors. Seminars In Diagnostic Pathology 2021, 39: 58-77. PMID: 34750021, DOI: 10.1053/j.semdp.2021.10.006.Peer-Reviewed Original ResearchMeSH KeywordsCarcinomaFemaleGenital Neoplasms, FemaleHumansImmunohistochemistryWorld Health OrganizationConceptsGynecologic carcinomasOvarian carcinomaPathology evaluationLower genital tract carcinomaMismatch repair protein immunohistochemistryGenital tract carcinomaPD-L1 testingFemale genital tumorsLower genital tractSignificant prognostic differencesPrediction of prognosisRoutine pathology practiceClassification of tumorsMucinous adenocarcinomaPrognostic differencesEndometrial carcinomaHuman papillomavirusGenital tumorsProtein immunohistochemistryWHO classificationPrecursor lesionsGenital tractDiagnostic confirmationDifferential diagnosisImmunohistochemical markers
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