2024
Residual Ultrasound-Enhancing Agents Mimicking Portal Venous Gas
Bitar R, Langdon J, Kaur M, Crandall I, McNamara R, Revzin M. Residual Ultrasound-Enhancing Agents Mimicking Portal Venous Gas. Ultrasound Quarterly 2024, 40: e00694. PMID: 39466239, DOI: 10.1097/ruq.0000000000000694.Peer-Reviewed Original ResearchConceptsUltrasound enhancing agentsPortal venous gasBowel ischemiaAbdominal ultrasoundVenous gasEchogenic fociContrast-enhanced echocardiographyEvaluation of cardiac functionPortal venous systemSeries of casesSonographic detectionCardiac functionDifferential diagnosisPortal veinVenous systemObservational studyLiver parenchymaPortal triadsVascular patencyBowelIschemiaEchocardiographyLiverUltrasoundProcoagulant phenotype of virus-infected pericytes is associated with portal thrombosis and intrapulmonary vascular dilations in fatal COVID-19
Cadamuro M, Lasagni A, Radu C, Calistri A, Pilan M, Valle C, Bonaffini P, Vitiello A, Toffanin S, Venturin C, Friòn-Herrera Y, Sironi S, Alessio M, Previtali G, Seghezzi M, Gianatti A, Strazzabosco M, Strain A, Campello E, Spiezia L, Palù G, Frigo A, Tosoni A, Nebuloni M, Parolin C, Sonzogni A, Simioni P, Fabris L. Procoagulant phenotype of virus-infected pericytes is associated with portal thrombosis and intrapulmonary vascular dilations in fatal COVID-19. Journal Of Hepatology 2024, 81: 872-885. PMID: 38908437, DOI: 10.1016/j.jhep.2024.06.014.Peer-Reviewed Original ResearchConceptsIntrapulmonary vascular dilatationWorsening respiratory failureSARS-CoV-2 infectionRespiratory failureFatal COVID-19Procoagulant phenotypeSARS-CoV-2Development of intrapulmonary vascular dilatationsVascular dilatationAssociated with portal thrombosisComplication of COVID-19 infectionTissue factorWork-up of patientsHuman pulmonary microvascular endothelial cellsEndothelial cellsObliterative portal venopathyPulmonary microvascular endothelial cellsAbsence of cirrhosisFatal respiratory failureAssociated with younger ageSevere liver diseaseDevelopment of hypoxemiaPathophysiology of thrombosisPortal vein branchesSevere COVID-19
2023
Hepatic Hypertrophy in Normal and Cirrhotic Livers Following Portal Vein Embolization: Comparative Assessment of 2 Different Embolic Regimens in a Large Animal Model
Kuhn T, Kahl V, Wang Y, Berz A, Shewarega A, Santana J, Antoch G, Chapiro J, Schlachter T, Madoff D. Hepatic Hypertrophy in Normal and Cirrhotic Livers Following Portal Vein Embolization: Comparative Assessment of 2 Different Embolic Regimens in a Large Animal Model. Journal Of Vascular And Interventional Radiology 2023, 34: 2162-2172.e2. PMID: 37634850, DOI: 10.1016/j.jvir.2023.08.024.Peer-Reviewed Original ResearchConceptsPortal vein embolizationFuture liver remnantVein embolizationLiver remnantCirrhotic liverStandardized future liver remnantNon-cirrhotic groupImmune cell infiltrationNon-cirrhotic liverN-butyl cyanoacrylateT-testFemale Yorkshire pigsLarge animal modelLarge animal studiesStudent's t-testCirrhotic groupEmbolized lobeBaseline percentageHepatic hypertrophyCell infiltrationBaseline CTKi-67Preclinical studiesInstitutional Animal CareFLR increaseIntravascular Ultrasound-Guided Percutaneous Creation of a Gastric Vein to Cava Shunt in a Patient with Variceal Hemorrhage and Portal Vein Occlusion
Atiles J, Cornman-Homonoff J, Schlachter T. Intravascular Ultrasound-Guided Percutaneous Creation of a Gastric Vein to Cava Shunt in a Patient with Variceal Hemorrhage and Portal Vein Occlusion. Journal Of Vascular And Interventional Radiology 2023, 34: 1278-1279. PMID: 37380248, DOI: 10.1016/j.jvir.2023.02.003.Peer-Reviewed Original Research
2022
Use of a Large-bore Thrombectomy Device for Portal Vein Thrombectomy in the Setting of Prior Transjugular Intrahepatic Portosystemic Shunt Reduction: A Report of 2 Cases
Cornman-Homonoff J, Parmar G, Perez Lozada JC, Marino AG. Use of a Large-bore Thrombectomy Device for Portal Vein Thrombectomy in the Setting of Prior Transjugular Intrahepatic Portosystemic Shunt Reduction: A Report of 2 Cases. Journal Of Vascular And Interventional Radiology 2022, 34: 310-312. PMID: 36283594, DOI: 10.1016/j.jvir.2022.10.024.Peer-Reviewed Original ResearchDragon 1 Protocol Manuscript: Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy
Korenblik R, Olij B, Aldrighetti LA, Hilal MA, Ahle M, Arslan B, van Baardewijk LJ, Baclija I, Bent C, Bertrand CL, Björnsson B, de Boer MT, de Boer SW, Bokkers RPH, Rinkes IHMB, Breitenstein S, Bruijnen RCG, Bruners P, Büchler MW, Camacho JC, Cappelli A, Carling U, Chan BKY, Chang DH, choi J, Font JC, Crawford M, Croagh D, Cugat E, Davis R, De Boo DW, De Cobelli F, De Wispelaere JF, van Delden OM, Delle M, Detry O, Díaz-Nieto R, Dili A, Erdmann JI, Fisher O, Fondevila C, Fretland Å, Borobia FG, Gelabert A, Gérard L, Giuliante F, Gobardhan PD, Gómez F, Grünberger T, Grünhagen DJ, Guitart J, Hagendoorn J, Heil J, Heise D, Herrero E, Hess GF, Hoffmann MH, Iezzi R, Imani F, Nguyen J, Jovine E, Kalff JC, Kazemier G, Kingham TP, Kleeff J, Kollmar O, Leclercq WKG, Ben SL, Lucidi V, MacDonald A, Madoff DC, Manekeller S, Martel G, Mehrabi A, Mehrzad H, Meijerink MR, Menon K, Metrakos P, Meyer C, Moelker A, Modi S, Montanari N, Navines J, Neumann UP, Peddu P, Primrose JN, Qu X, Raptis D, Ratti F, Ridouani F, Rogan C, Ronellenfitsch U, Ryan S, Sallemi C, Moragues JS, Sandström P, Sarriá L, Schnitzbauer A, Serenari M, Serrablo A, Smits MLJ, Sparrelid E, Spüntrup E, Stavrou GA, Sutcliffe RP, Tancredi I, Tasse JC, Udupa V, Valenti D, Fundora Y, Vogl TJ, Wang X, White SA, Wohlgemuth WA, Yu D, Zijlstra IAJ, Binkert CA, Bemelmans MHA, van der Leij C, Schadde E, van Dam RM. Dragon 1 Protocol Manuscript: Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy. CardioVascular And Interventional Radiology 2022, 45: 1391-1398. PMID: 35790566, PMCID: PMC9458562, DOI: 10.1007/s00270-022-03176-1.Peer-Reviewed Original ResearchConceptsFuture liver remnant hypertrophyHepatic vein embolizationMulticenter prospective single-arm trialResectable colorectal cancer liver metastasesColorectal cancer liver metastasesProspective single-arm trialFeasibility of resectionCancer liver metastasesDisease-free survivalSingle-arm trialSmall FLRPrimary endpointSecondary endpointsFLR hypertrophyLiver metastasesOverall survivalProspective trialVein embolizationLiver functionSafety profileArm trialLiver volumeWeek 1Week 3Study centers
2021
Balloon-assisted radioembolization via the proper hepatic artery to treat a left liver hepatocellular carcinoma and portal vein tumor thrombus with an inaccessible left hepatic artery: A case report
Mabey JG, Cornman-Homonoff J, Madoff DC. Balloon-assisted radioembolization via the proper hepatic artery to treat a left liver hepatocellular carcinoma and portal vein tumor thrombus with an inaccessible left hepatic artery: A case report. Clinical Imaging 2021, 82: 244-250. PMID: 34920388, DOI: 10.1016/j.clinimag.2021.11.026.Peer-Reviewed Case Reports and Technical NotesConceptsPortal vein tumor thrombusLeft hepatic arteryProper hepatic arteryHepatic arteryVein tumor thrombusHepatocellular carcinomaTransarterial radioembolizationTumor thrombusUse of TAREYttrium-90 transarterial radioembolizationTumor-feeding vesselsLiver hepatocellular carcinomaBalloon occlusionCase reportBalloon microcatheterVessel angulationEffective treatmentLiver parenchymaArteryTumor vesselsY microspheresRadiotracer activityRadioembolizationCarcinomaThrombusSystematic Reviews and Meta-Analyses of Portal Vein Embolization, Associated Liver Partition and Portal Vein Ligation, and Radiation Lobectomy Outcomes in Hepatocellular Carcinoma Patients
Charalel RA, Sung J, Askin G, Jo J, Mitry M, Chung C, Tmanova L, Madoff DC. Systematic Reviews and Meta-Analyses of Portal Vein Embolization, Associated Liver Partition and Portal Vein Ligation, and Radiation Lobectomy Outcomes in Hepatocellular Carcinoma Patients. Current Oncology Reports 2021, 23: 135. PMID: 34716800, DOI: 10.1007/s11912-021-01075-1.Peer-Reviewed Original ResearchConceptsPortal vein embolizationAssociated liver partitionPortal vein ligationHepatocellular carcinoma patientsSystematic reviewVein embolizationCarcinoma patientsMajor complicationsPooled proportionVein ligationLiver partitionLow major complication rateMajor complication ratePurpose of ReviewToRandom-effects modelWeb of ScienceEffective hypertrophyFLR hypertrophyComplication rateOvid EmbaseCochrane LibraryHCC patientsLiver hypertrophyOvid MEDLINEInclusion criteriaVascular Liver Disorders, Portal Vein Thrombosis, and Procedural Bleeding in Patients With Liver Disease: 2020 Practice Guidance by the American Association for the Study of Liver Diseases
Northup PG, Garcia‐Pagan J, Garcia‐Tsao G, Intagliata NM, Superina RA, Roberts LN, Lisman T, Valla DC. Vascular Liver Disorders, Portal Vein Thrombosis, and Procedural Bleeding in Patients With Liver Disease: 2020 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology 2021, 73: 366-413. PMID: 33219529, DOI: 10.1002/hep.31646.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2020
Key histopathologic features in idiopathic noncirrhotic portal hypertension: an interobserver agreement study and proposal for diagnostic criteria
Liang J, Shi C, Dupont WD, Salaria SN, Huh WJ, Correa H, Roland JT, Perri RE, Washington MK. Key histopathologic features in idiopathic noncirrhotic portal hypertension: an interobserver agreement study and proposal for diagnostic criteria. Modern Pathology 2020, 34: 592-602. PMID: 32958831, DOI: 10.1038/s41379-020-00676-8.Peer-Reviewed Original ResearchConceptsIdiopathic noncirrhotic portal hypertensionObliterative portal venopathyNoncirrhotic portal hypertensionPortal hypertensionLiver biopsyDiagnostic criteriaInterobserver agreement studyHistologic featuresHistopathologic diagnostic criteriaOriginal pathologic diagnosisPractical diagnostic criteriaAgreement studyKey histopathologicPortal venopathyVein sclerosisHistologic predictorsClinicopathologic correlationHistologic diagnosisPathologic diagnosisHistologic assessmentExperienced hepatopathologistsClinical informationHypertensionBiopsyThree-tiered classificationImproving the Safety of Major Resection for Hepatobiliary Malignancy: Portal Vein Embolization and Recent Innovations in Liver Regeneration Strategies
Madoff DC, Odisio BC, Schadde E, Gaba RC, Bennink RJ, van Gulik TM, Guiu B. Improving the Safety of Major Resection for Hepatobiliary Malignancy: Portal Vein Embolization and Recent Innovations in Liver Regeneration Strategies. Current Oncology Reports 2020, 22: 59. PMID: 32415401, DOI: 10.1007/s11912-020-00922-x.Peer-Reviewed Original ResearchConceptsPortal vein embolizationFuture liver remnantFLR hypertrophyMajor hepatectomyVein embolizationHepatobiliary malignanciesCT volumetryAppropriate surgical candidatesExtent of resectionPortal vein ligationRadiation lobectomyVenous deprivationMajor resectionPerformance statusSurgical candidatesComplication rateLiver diseaseVein ligationLiver partitionLiver remnantTumor typesPhysiological imagingResectionEmbolizationMalignancy
2019
Transhepatic portal stent placement and jejunal varix embolization for management of treatment-limiting gastrointestinal bleeding in a patient with unresectable recurrent intrahepatic cholangiocarcinoma
Cornman-Homonoff J, Bassik N, Madoff DC. Transhepatic portal stent placement and jejunal varix embolization for management of treatment-limiting gastrointestinal bleeding in a patient with unresectable recurrent intrahepatic cholangiocarcinoma. Clinical Imaging 2019, 59: 188-191. PMID: 31837541, DOI: 10.1016/j.clinimag.2019.09.012.Peer-Reviewed Case Reports and Technical NotesConceptsRecurrent cholangiocarcinomaOnly potential cureRecurrent intrahepatic cholangiocarcinomaPoor patient outcomesUnresectable diseaseGastrointestinal bleedingChemotherapy administrationMyelosuppressive effectsTherapeutic mainstayDismal prognosisIntrahepatic cholangiocarcinomaVariceal embolizationStent placementPortal veinPatient outcomesPotential cureCholangiocarcinomaEmbolizationCytopeniasBleedingRegimenChemotherapyPatientsSurgeryPrognosisCase 4: Large-Volume Hematemesis in a 16-year-old Boy
Dasgupta S, Olaloye O, Pierce M, Glaser A. Case 4: Large-Volume Hematemesis in a 16-year-old Boy. Pediatrics In Review 2019, 40: 538-542. PMID: 31575807, DOI: 10.1542/pir.2017-0065.Peer-Reviewed Original ResearchManagement of patients with hepatocellular carcinoma and portal vein tumour thrombosis: comparing east and west
Lu J, Zhang XP, Zhong BY, Lau WY, Madoff DC, Davidson JC, Qi X, Cheng SQ, Teng GJ. Management of patients with hepatocellular carcinoma and portal vein tumour thrombosis: comparing east and west. The Lancet Gastroenterology & Hepatology 2019, 4: 721-730. PMID: 31387735, DOI: 10.1016/s2468-1253(19)30178-5.Peer-Reviewed Original ResearchMeSH KeywordsAnilidesAntibodies, Monoclonal, HumanizedAntineoplastic AgentsCarcinoma, HepatocellularChemoembolization, TherapeuticEndovascular ProceduresHepatectomyHepatic ArteryHumansInfusions, Intra-ArterialLiver NeoplasmsLiver TransplantationNivolumabPatient Care TeamPhenylurea CompoundsPortal VeinPyridinesQuinolinesRadiotherapy, AdjuvantSorafenibStentsVenous ThrombosisConceptsPortal vein tumor thrombosisTumor thrombosisHepatocellular carcinomaOptimise treatment strategiesTranscatheter arterial therapyAdvanced hepatocellular carcinomaManagement of patientsArterial therapySurgical treatmentTreatment strategiesPhysician preferenceNovel treatmentsCarcinomaThrombosisMultidisciplinary teamPatientsReimbursement schemesTreatmentRevascularisationComorbiditiesManagementPrognosisRadiotherapyActive managementTherapyManagement of Advanced Stage Hepatocellular Carcinoma with Extensive Portal Vein Tumor Thrombus Using an Adjustable Dual Balloon Occlusion Technique
Madoff DC, Kim D, Holzwanger DJ, Kishore SA, Friedman T. Management of Advanced Stage Hepatocellular Carcinoma with Extensive Portal Vein Tumor Thrombus Using an Adjustable Dual Balloon Occlusion Technique. Journal Of Vascular And Interventional Radiology 2019, 30: 1145-1147. PMID: 31133450, DOI: 10.1016/j.jvir.2019.01.006.Peer-Reviewed Original ResearchEndoscopic Ultrasound for the Diagnosis and Staging of Liver Tumors
Lange A, Muniraj T, Aslanian HR. Endoscopic Ultrasound for the Diagnosis and Staging of Liver Tumors. Gastrointestinal Endoscopy Clinics Of North America 2019, 29: 339-350. PMID: 30846157, DOI: 10.1016/j.giec.2018.12.005.Peer-Reviewed Original ResearchConceptsEndoscopic ultrasound examinationUltrasound examinationFine-needle aspirationPortal veinNeedle aspirationLiver lesionsCross-sectional imagingIndeterminate liver lesionsFocal liver lesionsLocoregional nodesLymph nodesLiver malignanciesCancer stagingEndoscopic ultrasoundLiver tumorsTechnologic improvementsLesionsExaminationStagingDiagnosisVeinAspirationMalignancyTumorsLiver
2018
Total Laparoscopic Pancreaticoduodenectomy with Venous Reconstruction for Pancreatic Head Cancer with Involvement of the Superior Mesenteric Vein–Portal Vein Confluence
Garbarino G, Fuks D, Cowan J, Ward M, Moisan F, Donatelli G, Beaussier M, Gayet B. Total Laparoscopic Pancreaticoduodenectomy with Venous Reconstruction for Pancreatic Head Cancer with Involvement of the Superior Mesenteric Vein–Portal Vein Confluence. Annals Of Surgical Oncology 2018, 25: 4035-4036. PMID: 30218250, DOI: 10.1245/s10434-018-6762-5.Peer-Reviewed Original ResearchConceptsSuperior mesenteric vein-portal vein confluencePancreatic head cancerVein involvementHead cancerVenous reconstructionCycles of neoadjuvant chemotherapyCases of pancreatic head cancerHead of the pancreasComplete such proceduresSuperior mesenteric veinEndoscopic retrograde cholangiopancreatographyFine-needle aspirationPancreatico-gastric anastomosisComputed tomography scanAdvanced laparoscopic skillsRight lateral aspectNeoadjuvant chemotherapyLaparoscopic pancreaticoduodenectomyBlood lossResultsOperative timeBackgroundLaparoscopic pancreaticoduodenectomyRetrograde cholangiopancreatographySubxiphoid incisionHospital stayTomography scanEvolution of Intrahepatic Shunts in a Patient With Hereditary Hemorrhagic Telangiectasia.
Haghighat L, Brandt EJ, Proctor DD, Garcia-Tsao G, Pollak J, Young L. Evolution of Intrahepatic Shunts in a Patient With Hereditary Hemorrhagic Telangiectasia. Annals Of Internal Medicine 2018, 169: 508-509. PMID: 29868721, DOI: 10.7326/l18-0036.Peer-Reviewed Case Reports and Technical NotesClinical Experience with Real-Time 3-D Guidance Based on C-Arm-Acquired Cone-Beam CT (CBCT) in Transjugular Intrahepatic Portosystemic Stent Shunt (TIPSS) Placement
Böning G, Lüdemann WM, Chapiro J, Jonczyk M, Hamm B, Günther RW, Gebauer B, Streitparth F. Clinical Experience with Real-Time 3-D Guidance Based on C-Arm-Acquired Cone-Beam CT (CBCT) in Transjugular Intrahepatic Portosystemic Stent Shunt (TIPSS) Placement. CardioVascular And Interventional Radiology 2018, 41: 1035-1042. PMID: 29541837, DOI: 10.1007/s00270-018-1877-4.Peer-Reviewed Original ResearchMeSH KeywordsCone-Beam Computed TomographyFeasibility StudiesFemaleFluoroscopyHepatic VeinsHumansHypertension, PortalImaging, Three-DimensionalMaleMiddle AgedPortal VeinPortasystemic Shunt, Transjugular IntrahepaticProspective StudiesPuncturesRadiography, InterventionalRetrospective StudiesStentsTreatment OutcomeUltrasonographyConceptsPuncture attemptsTIPSS placementTIPSS procedureProcedure timeTransjugular intrahepatic portosystemic stent shunt placementMean puncture timeSuccess ratePortal vein punctureSignificant differencesShunt placementPuncture timeConsecutive casesMedian numberProspective groupVein punctureUS guidanceClinical experienceControl groupCone beamStudy designCone-beam CTMean timeDoseCBCT guidancePatients
2017
Novel application and serial evaluation of tissue-engineered portal vein grafts in a murine model
Maxfield MW, Stacy MR, Kurobe H, Tara S, Yi T, Cleary MA, Zhuang ZW, Rodriguez-Davalos MI, Emre SH, Iwakiri Y, Shinoka T, Breuer CK. Novel application and serial evaluation of tissue-engineered portal vein grafts in a murine model. Regenerative Medicine 2017, 12: 929-938. PMID: 29215317, PMCID: PMC5827823, DOI: 10.2217/rme-2017-0021.Peer-Reviewed Original Research
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