2025
Resistance Analyses in Heavily Treatment-Experienced People With HIV Treated With the Novel HIV Capsid Inhibitor Lenacapavir After 2 Years
Margot N, Jogiraju V, Pennetzdorfer N, Naik V, VanderVeen L, Ling J, Singh R, Dvory-Sobol H, Ogbuagu O, Segal-Maurer S, Molina J, Rhee M, Callebaut C. Resistance Analyses in Heavily Treatment-Experienced People With HIV Treated With the Novel HIV Capsid Inhibitor Lenacapavir After 2 Years. The Journal Of Infectious Diseases 2025, jiaf050. PMID: 39873394, DOI: 10.1093/infdis/jiaf050.Peer-Reviewed Original ResearchOptimized background regimenHIV-1HIV-1 RNA <HIV-1 RNA suppressionTreatment-experienced peopleTandem liquid chromatography/mass spectrometryFirst-in-class inhibitorResistant to 2HIV-1 capsidBackground regimenTreatment-experiencedVirological failureLenacapavirRNA suppressionDrug classesDrug measurementsResistance assaysMonotherapyPWHLiquid chromatography/mass spectrometryTreatmentDrugResistance analysisResuppressionYearsTrends in Osteoporosis Drug Therapy Receipt Among Commercial and Medicare Advantage Enrollees in the United States, 2011-2022
Everhart A, Brito J, Clarke B, Herrin J, Karaca-Mandic P, Kennel K, Parimi N, Rosen C, Takagi M, McCoy R. Trends in Osteoporosis Drug Therapy Receipt Among Commercial and Medicare Advantage Enrollees in the United States, 2011-2022. The Journal Of Clinical Endocrinology & Metabolism 2025, dgae840. PMID: 39811927, DOI: 10.1210/clinem/dgae840.Peer-Reviewed Original ResearchOsteoporosis drug therapyFragility fracturesDocumented osteoporosisUndertreatment of osteoporosisMedicare Advantage enrolleesOptumLabs Data WarehouseUnderdiagnosis of osteoporosisHealth insuranceTherapy receiptPrimary outcomeRetrospective analysisDrug therapyOsteoporosisCuzick's testWomenMedicarePatientsUnderdiagnosisUnited StatesFilling rateSexLow rateAgeFractureYearsForecasting the use of chiropractic services within the Veterans Health Administration.
Bensel V, Corcoran K, Lisi A. Forecasting the use of chiropractic services within the Veterans Health Administration. PLOS ONE 2025, 20: e0316924. PMID: 39804852, PMCID: PMC11729958, DOI: 10.1371/journal.pone.0316924.Peer-Reviewed Original ResearchConceptsCommunity Care NetworkVeterans Health AdministrationChiropractic servicesHealth AdministrationFiscal yearVA chiropractic servicesVA Corporate Data WarehouseCorporate Data WarehouseCross-sectional analysisChiropractic careVA usersCare networkHealthcare usersCareOverall useCompound annual growth rateUse ratesResource needsVeteransUse dataServicesIncreased useUseYearsData warehouse
2024
Increasing patient viewership of complex imaging reports: The paradox of the Cures Act
Amin K, Davis M, Naderi A, Forman H. Increasing patient viewership of complex imaging reports: The paradox of the Cures Act. Clinical Imaging 2024, 119: 110398. PMID: 39756146, DOI: 10.1016/j.clinimag.2024.110398.Peer-Reviewed Original ResearchConceptsElectronic health recordsCentury Cures ActCures ActImprove patient experienceRadiology reportsReading grade levelPatient experienceHealth recordsHealth informationRecommended levelsRetrospective observational studyObservational studyPatientsViewing probabilityRadiologyOddsHealthYearsIncrease viewershipReportsGrade levelModalitiesProvisionAppointment non-attendance is associated with disease modifying therapy persistence the following year
Gromisch E, Turner A, Leipertz S, Beauvais J, Haselkorn J. Appointment non-attendance is associated with disease modifying therapy persistence the following year. Multiple Sclerosis And Related Disorders 2024, 92: 106179. PMID: 39571216, DOI: 10.1016/j.msard.2024.106179.Peer-Reviewed Original ResearchAppointment non-attendanceNon-attendanceElectronic health record dataVeterans with MSHealth record dataDisease modifying therapiesHealthcare providersNon-attendance behaviorInitial disease modifying therapiesMultiple sclerosisRecord dataLogistic regressionAppointmentProportion of NSNon-persistenceAssociated with non-persistenceVeteransTime frameDemographicsData repositoriesYearsPersonsHealthcareModifying therapiesProportionComparison of the GoCheck Kids and Spot Screener photoscreening devices for the detection of amblyopia risk factors using 2021 AAPOS recommendations
Applebaum S, Sopeyin A, Mohamedali A, Walsh E, Rotruck J, Njike V, Howard M. Comparison of the GoCheck Kids and Spot Screener photoscreening devices for the detection of amblyopia risk factors using 2021 AAPOS recommendations. Journal Of American Association For Pediatric Ophthalmology And Strabismus 2024, 28: 104035. PMID: 39528078, DOI: 10.1016/j.jaapos.2024.104035.Peer-Reviewed Original ResearchAmblyopia risk factorsComplete eye examinationPositive predictive valueAAPOS guidelinesVision screeningDetection of amblyopia risk factorsPediatric vision screeningFailed vision screeningReceiver operating characteristicRisk factorsPhotoscreening devicesPediatric ophthalmologistsAAPOSEye examinationPrimary outcomeStatistically significant differencePredictive valueGuidelinesSignificant differenceParticipantsPhotoscreeningStrabismusScreeningYearsOperating characteristicsHormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in BRCA1 and BRCA2
Phillips K, Kotsopoulos J, Domchek S, Terry M, Chamberlain J, Bassett J, Aeilts A, Andrulis I, Buys S, Cui W, Daly M, Eisen A, Foulkes W, Friedlander M, Gronwald J, Hopper J, John E, Karlan B, Kim R, Kurian A, Lubinski J, Metcalfe K, Nathanson K, Singer C, Southey M, Symecko H, Tung N, Narod S, Milne R, the Risk Factor Analysis of Hereditary Breast and Ovarian Cancer Study T, Study T, Amor D, Andrews L, Antill Y, Balleine R, Beesley J, Bennett I, Bogwitz M, Bodek S, Botes L, Brennan M, Brown M, Buckley M, Burke J, Butow P, Caldon L, Campbell I, Cao M, Chakrabarti A, Chauhan D, Chauhan M, Chenevix-Trench G, Christian A, Cohen P, Colley A, Crook A, Cui J, Courtney E, Cummings M, Dawson S, DeFazio A, Delatycki M, Dickson R, Dixon J, Edwards S, Farshid G, Fellows A, Fenton G, Field M, Flanagan J, Fong P, Forrest L, Fox S, French J, Friedlander M, Gaff C, Gattas M, George P, Greening S, Harris M, Hart S, Harraka P, Hayward N, Hopper J, Hoskins C, Hunt C, James P, Jenkins M, Kidd A, Kirk J, Koehler J, Kollias J, Lakhani S, Lawrence M, Lee J, Li S, Lindeman G, Lippey J, Lipton L, Lobb L, Loi S, Mann G, Marsh D, McLachlan S, Meiser B, Milne R, Nightingale S, O'Connell S, O'Sullivan S, Ortega D, Pachter N, Pang J, Pathak G, Patterson B, Pearn A, Phillips K, Pieper E, Ramus S, Rickard E, Ragunathan A, Robinson B, Saleh M, Skandarajah A, Salisbury E, Saunders C, Saunus J, Savas P, Scott R, Scott C, Sexton A, Shaw J, Shelling A, Srinivasa S, Simpson P, Southey M, Spurdle A, Taylor J, Taylor R, Thorne H, Trainer A, Tucker K, Visvader J, Walker L, Williams R, Winship I, Young M, Zaheed M. Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in BRCA1 and BRCA2. Journal Of Clinical Oncology 2024, 43: 422-431. PMID: 39356978, PMCID: PMC11771360, DOI: 10.1200/jco.24.00176.Peer-Reviewed Original ResearchAssociated with increased BC riskBC riskHormonal contraceptionMutation carriersBreast cancerAssociated with BC riskCarriers of germline mutationsBreast cancer riskMedian follow-upAssociated with increased riskIncreased breast cancerHormonal contraceptive useProspective cohort studyGermline mutationsFollow-upCohort studyCox regressionCancer riskContraceptive useContraceptionCumulative durationMutationsRiskProportional increaseYearsDifferential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations
Hua L, Solomon A, Tenembaum S, Scalfari A, Rovira À, Rostasy K, Newsome S, Marrie R, Magyari M, Kantarci O, Hemmer B, Hemingway C, Harnegie M, Graves J, Cohen J, Bove R, Banwell B, Corboy J, Waubant E. Differential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations. JAMA Neurology 2024, 81: 1210-1222. PMID: 39283621, DOI: 10.1001/jamaneurol.2024.3062.Peer-Reviewed Original ResearchDifferential diagnosisMultiple sclerosisAdult-onset MSClinical presentation of MSPresentation of MSNon-MS diagnosisClinical presentationAdult MSSuspected MSNeuronal injuryLate-onsetConsensus guidanceDiagnostic approachApproximately 5%Age groupsDiagnosisRed flagsMS expertsAgeEarly adulthoodBiological differencesSclerosisOlder adultsYearsAdultsAdults With Spina Bifida Fare Worse Than Young Adults: A Systemic Vulnerability in Urinary Tract Infection–Related Hospital Care
Huen K, Davis-Dao C, Sayrs L, Ehwerhemuepha L, Martin-King C, Kain Z. Adults With Spina Bifida Fare Worse Than Young Adults: A Systemic Vulnerability in Urinary Tract Infection–Related Hospital Care. Journal Of Urology 2024, 212: 749-756. PMID: 38950379, DOI: 10.1097/ju.0000000000004130.Peer-Reviewed Original ResearchSB patientsSpina bifidaAdult SB patientsRetrospective cohort analysisGender-matched controlsLogistic regression analysisCohort analysisHospital carePatientsSB casesOddsCerner Real World DataRegression analysisHealth care utilizationYoung adultsAdolescentsAdultsCare utilizationReal World DataAgeYearsUTICareUrinaryComorbiditiesAssociation of Medical School Gap Year Research and Degree Programs With Otolaryngology Interview and Match Outcomes
Boyi T, Benjamin W, Lenze N, Brenner M, Mihalic A, Kupfer R, Judson B, Lee Y. Association of Medical School Gap Year Research and Degree Programs With Otolaryngology Interview and Match Outcomes. Annals Of Otology Rhinology & Laryngology 2024, 133: 783-791. PMID: 38887016, DOI: 10.1177/00034894241261821.Peer-Reviewed Original ResearchLong-term career outcomesCross-sectional analysisApplicant respondentsMedical schoolsPrimary outcomeResidency interviewsLongitudinal studyUSMLE scoresInterviewsOtolaryngologyTexas Seeking TransparencyMaster's degreeNo significant differenceOutcomesMatch successGap yearDegree programsYearsSignificant differenceClerkship honorsOtolaryngology applicantsResearch experienceTwenty Years of Get With The Guidelines-Stroke: Celebrating Past Successes, Lessons Learned, and Future Challenges
Reeves M, Fonarow G, Smith E, Sheth K, Messe S, Schwamm L. Twenty Years of Get With The Guidelines-Stroke: Celebrating Past Successes, Lessons Learned, and Future Challenges. Stroke 2024, 55: 1689-1698. PMID: 38738376, PMCID: PMC11208062, DOI: 10.1161/strokeaha.124.046527.Peer-Reviewed Original ResearchMedicaid Acceptance Varies by Physician Seniority and Specialty in California
Torabi S, Nguyen T, Du A, Birkenbeuel J, Manes R, Kuan E. Medicaid Acceptance Varies by Physician Seniority and Specialty in California. Population Health Management 2024, 27: 185-191. PMID: 38629631, DOI: 10.1089/pop.2024.0006.Peer-Reviewed Original ResearchMedi-CalGraduation yearNational Provider IdentifierYear of graduationPhysician seniorityPhysician yearsEmergency medicineStratify physiciansProvider IdentifierMedicare providersCalifornia physiciansInternal medicineInsurance acceptancePhysiciansSpecialtyMedicareMedicaidGeneral surgeryInsuranceHighest percentAcceptanceGraduatesMedicineYearsRehabilitationReinterventions After CoreValve/Evolut Transcatheter or Surgical Aortic Valve Replacement for Treatment of Severe Aortic Stenosis
Grubb K, Lisko J, O'Hair D, Merhi W, Forrest J, Mahoney P, Van Mieghem N, Windecker S, Yakubov S, Williams M, Chetcuti S, Deeb G, Kleiman N, Althouse A, Reardon M. Reinterventions After CoreValve/Evolut Transcatheter or Surgical Aortic Valve Replacement for Treatment of Severe Aortic Stenosis. JACC Cardiovascular Interventions 2024, 17: 1007-1016. PMID: 38573257, DOI: 10.1016/j.jcin.2024.01.292.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansIncidenceMalePostoperative ComplicationsProsthesis DesignRandomized Controlled Trials as TopicRetreatmentRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementIncidence of reinterventionAortic valve replacementCumulative incidence of reinterventionValve replacementValve reinterventionCumulative incidenceCoreValve transcatheter aortic valve replacementLow incidence of reinterventionSurgical aortic valve replacement patientsSingle-arm studyFirst-generation CoreValveEvolut R/ProParavalvular regurgitationReinterventionRandomized trialsLow incidenceCoreValvePooled dataTranscatheterIncidenceTreatmentYearsEndocarditisPrediction of metabolic syndrome following a first pregnancy
Kawakita T, Greenland P, Pemberton V, Grobman W, Silver R, Bairey Merz C, McNeil R, Haas D, Reddy U, Simhan H, Saade G. Prediction of metabolic syndrome following a first pregnancy. American Journal Of Obstetrics And Gynecology 2024, 231: 649.e1-649.e19. PMID: 38527600, PMCID: PMC11424779, DOI: 10.1016/j.ajog.2024.03.031.Peer-Reviewed Original ResearchDevelopment of metabolic syndromeArea under the receiver operating characteristic curveMetabolic syndromeNational Cholesterol Education Program Adult Treatment Panel III criteriaAdult Treatment Panel III criteriaPrevalence of metabolic syndromePrediction of metabolic syndromeProspective cohort studyIn-personSecondary analysisCohort studyIII criteriaInclusion criteriaPregnant individualsPrimary outcomeReceiver operating characteristic curveVisit 2Regression modelsPregnancySyndromeDeliveryUnited StatesCharacteristic curveLASSO regression modelYears‘If I don’t take care of me, then I can’t be there for others:’ a qualitative study of caregiving relationships among older women living with HIV
Vu T, Quinn M, Womack J, Monin J. ‘If I don’t take care of me, then I can’t be there for others:’ a qualitative study of caregiving relationships among older women living with HIV. Aging & Mental Health 2024, 28: 1304-1315. PMID: 38327025, DOI: 10.1080/13607863.2024.2313729.Peer-Reviewed Original ResearchCare networkHIV managementOlder womenPublic health programsCommunity-based organizationsPopulation of womenCare recipientsHealthcare discussionsOWLHHealth programsThematic analysisParticipants 1Qualitative studyCaregiversSemi-structuredCareEducational effortsHIVSources of meaningWomenParticipantsPerformance contentHealthcareYearsHealthTen years of research on the treatments of internet gaming disorder: A scoping review and directions for future research
Dong G, Dai J, Potenza M. Ten years of research on the treatments of internet gaming disorder: A scoping review and directions for future research. Journal Of Behavioral Addictions 2024, 13: 51-65. PMID: 38183434, PMCID: PMC10988415, DOI: 10.1556/2006.2023.00071.Peer-Reviewed Original ResearchNon-invasive brain stimulationCognitive behavioral therapyTreatment strategiesTreatment studiesInternet gaming disorderMedication-based treatmentDifferent treatment strategiesStudies of treatmentTreatment of IGDFuture studiesBrain stimulationControl groupBehavioral therapyGaming disorderTreatmentDSM-5Sex differencesDisordersSummary of findingsCurrent studyEarly stagesPharmacotherapyTherapyStudyYears
2023
PERSONS LIVING WITH DEMENTIA AND MULTIPLE CHRONIC CONDITIONS IDENTIFYING HEALTH PRIORITIES WITH CARE PARTNERS
Vu T, Mroz E, Hernandez-Bigos K, Chow D, Samper-Ternent R, Johnson K, Tinetti M, Monin J. PERSONS LIVING WITH DEMENTIA AND MULTIPLE CHRONIC CONDITIONS IDENTIFYING HEALTH PRIORITIES WITH CARE PARTNERS. Innovation In Aging 2023, 7: 416-416. PMCID: PMC10736172, DOI: 10.1093/geroni/igad104.1374.Peer-Reviewed Original ResearchMultiple chronic conditionsHealth care prioritiesCare partnersChronic conditionsHealth priorityCare prioritiesPilot studyYears of ageEvidence-based toolsPatient prioritiesOlder personsPLWDCare decisionsHealth goalsCare recipientsHealthcare goalsOlder adultsDementiaOpen-ended questionsAgeThematic analysisPERSONS LIVINGEarly stagesYearsRecipientsHow Good Are Cardiologists at Predicting Major Adverse Events in Fontan Patients?
Elder R, Valente A, Davey B, Wu F, Drucker N, Lombardi K, Lee S, McCollum S, Shabanova V, St. Clair N, Azcue N, Toro-Salazar O, Rathod R. How Good Are Cardiologists at Predicting Major Adverse Events in Fontan Patients? JACC Advances 2023, 3: 100736. PMID: 38939804, PMCID: PMC11198720, DOI: 10.1016/j.jacadv.2023.100736.Peer-Reviewed Original ResearchMajor adverse eventsBeta-blocker useFontan patientsSimple kappa coefficientAdverse eventsAtrioventricular valve regurgitationBlocker useSystolic dysfunctionCardiac admissionsValve regurgitationRisk cohortMulticenter studyPatientsResults OverallLateral tunnelLinear mixed effects modelsCardiologistsFontanKappa coefficientMixed effects modelsEffects modelRiskMonthsYearsRegurgitationHuman Papillomavirus Vaccination Status and Correlates Among Mid-Adult Women: Connecticut, USA, 2016–2019
Sheth S, Johnson N, Sullivan E, Torres A, Oliveira C, Niccolai L. Human Papillomavirus Vaccination Status and Correlates Among Mid-Adult Women: Connecticut, USA, 2016–2019. Journal Of Women's Health 2023, 33: 28-32. PMID: 37943625, PMCID: PMC10794823, DOI: 10.1089/jwh.2022.0456.Peer-Reviewed Original ResearchConceptsMid-adult womenVaccination statusHPV vaccinationHPV vaccineHuman Papillomavirus Vaccination StatusHPV vaccination statusHuman papillomavirus vaccinationAge 26 yearsHealth care providersCross-sectional surveyPapillomavirus vaccinationUnvaccinated womenVaccinated womenVaccine informationCare providersVaccinationAdult womenVaccineWomenBehavioral correlatesCorrelatesStatusPotential benefitsYearsParticipantsAfter 50 Years, Health Professional Shortage Areas Had No Significant Impact On Mortality Or Physician Density
Markowski J, Wallace J, Ndumele C. After 50 Years, Health Professional Shortage Areas Had No Significant Impact On Mortality Or Physician Density. Health Affairs 2023, 42: 1507-1516. PMID: 37931191, DOI: 10.1377/hlthaff.2023.00478.Peer-Reviewed Original Research
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