2025
Safety of Stimulants Across Patient Populations
Oliva H, Prudente T, Mayerson T, Mignosa M, Oliva I, Potenza M, Jegede O, Angarita G. Safety of Stimulants Across Patient Populations. JAMA Network Open 2025, 8: e259492. PMID: 40343695, PMCID: PMC12065045, DOI: 10.1001/jamanetworkopen.2025.9492.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderRandomized clinical trialsAdverse eventsStimulant medicationData extractionSafety of stimulationRisk ratioIncreased riskMethodological quality assessmentPreferred Reporting ItemsPatient populationClinical conditionsDiverse patient populationsRisk of biasSafety of stimulant medicationsUnclear risk of biasTreatment of attention-deficit/hyperactivity disorderOverall AEsRandom-effects modelWeb of ScienceBinge eating disorderStimulant use disorderComprehensive literature searchMain OutcomesReporting ItemsCraniosynostosis among children with X-linked hypophosphatemia: A systematic review and meta-analysis
Fisch S, Tudor A, Benchekroun E, Landsberg W, Feldstein N, Lamb M, Carpenter T, Rundle A, Jacobson J, Neugut A, Freedberg D. Craniosynostosis among children with X-linked hypophosphatemia: A systematic review and meta-analysis. Bone 2025, 196: 117488. PMID: 40220947, DOI: 10.1016/j.bone.2025.117488.Peer-Reviewed Original ResearchX-linked hypophosphatemiaPrevalence of craniosynostosisPooled prevalenceSystematic reviewMeta-analysisRandom-effects modelWeb of SciencePediatric populationSkull abnormalitiesCohort studyImpaired phosphate reabsorptionElevated FGF23 levelsPrevalenceFemale predominanceCase seriesFGF23 levelsPhosphate reabsorptionGene variantsChildrenIncreased vigilanceCraniosynostosisAbnormal bone growthGenetic disordersHypophosphatemiaAbnormalitiesThe association between internet-use-disorder symptoms and loneliness: a systematic review and meta-analysis with a categorical approach
Mestre-Bach G, Paiva U, San Martín Iniguez L, Beranuy M, Martín-Vivar M, Mallorquí-Bagué N, Normand E, Chicote M, Potenza M, Arrondo G. The association between internet-use-disorder symptoms and loneliness: a systematic review and meta-analysis with a categorical approach. Psychological Medicine 2025, 55: e77. PMID: 40071718, DOI: 10.1017/s0033291725000376.Peer-Reviewed Original ResearchConceptsInternet-use disordersSystematic reviewMeta-analysisInternet-useInternet use disorderRandom-effects modelWeb of ScienceDegree of lonelinessUCLA Loneliness ScaleStatistical poolingQuantify associationsOdds ratioCohen's dDisorder symptomsGreater lonelinessMeta-regressionPooled differenceEffect sizePre-registeredUCLA-LonelinessLonelinessEffects of ageCategorical approachSymptomsGroup of individualsUnderstanding oncologic emergencies and related emergency department visits and hospitalizations: a systematic review
Yilmaz S, Aryal K, King J, Bischof J, Hong A, Wood N, Gould Rothberg B, Hudson M, Heinert S, Wattana M, Coyne C, Reyes-Gibby C, Todd K, Lyman G, Klotz A, Abar B, Grudzen C, Bastani A, Baugh C, Henning D, Bernstein S, Rico J, Ryan R, Yeung S, Qdaisat A, Padela A, Madsen T, Liu R, Adler D. Understanding oncologic emergencies and related emergency department visits and hospitalizations: a systematic review. BMC Emergency Medicine 2025, 25: 40. PMID: 40045233, PMCID: PMC11883922, DOI: 10.1186/s12873-025-01183-2.Peer-Reviewed Original ResearchConceptsEmergency departmentEmergency visitsPredictors of ED usePeer-reviewed original research studiesSystematic reviewOncologic emergencyCancer incidence ratesCare delivery pathwaysGeriatric oncology researchManagement of oncologic emergenciesEmergency department visitsResultsThe search strategyTreatment side effectsOriginal research studiesCancer patientsVulnerable patient populationAcute careSingle-site studyWeb of ScienceCare venuesED useDepartment visitsHealth systemED visitsED presentationsExamining the Impact of the Syndemic on Black Birthing Individuals in the USA: a Systematic Review
Wisniewski K, Henry N, Flanagan A, Popoola A, Weaver N, Iglio L, Alexandre C, Myers D, Tieu T, Waller R, Kornfield S, Gur R, Momplaisir F, Njoroge W. Examining the Impact of the Syndemic on Black Birthing Individuals in the USA: a Systematic Review. Journal Of Racial And Ethnic Health Disparities 2025, 1-15. PMID: 39994154, DOI: 10.1007/s40615-025-02311-1.Peer-Reviewed Original ResearchBirthing individualsSystematic reviewMaternal health disparitiesWork-related challengesHealthcare discriminationPeer-reviewed articlesHealth disparitiesPostpartum experiencesSystemic racismWeb of ScienceInclusion criteriaAbstracted dataPRISMA guidelinesWell-beingMinoritized populationsScreening studiesPeer reviewFamily relationshipsCOVID-19COVID-19 pandemicSyndemicsThemesPublished literatureIndividual experienceCoronavirus disease 2019Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis
Sumsuzzman D, Ye Y, Wang Z, Pandey A, Langley J, Galvani A, Moghadas S. Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis. BMC Infectious Diseases 2025, 25: 215. PMID: 39948450, PMCID: PMC11827239, DOI: 10.1186/s12879-025-10610-5.Peer-Reviewed Original ResearchConceptsPopulation settingEffective public health strategiesConfidence intervalsImpact of disease severityModified Newcastle-Ottawa ScalePublic health strategiesHigher secondary attack rateRisk of biasNewcastle-Ottawa ScalePandemic responseGlobal systematic reviewRandom-effects modelFreeman-Tukey double arcsine transformationWeb of ScienceNo significant associationDrivers of SARS-CoV-2 transmissionHealth strategiesSecondary attack rateSARS-CoV-2Disease severityEffective pandemic responseTargeted interventionsDouble arcsine transformationOvid MEDLINESystematic reviewA systematic review on the assessment of pregnancy-specific psychological trauma during pregnancy: A call to action
Givrad S, Wall K, Goldman L, Shin J, Novak E, Lowell A, Penner F, Day M, Papa L, Wright D, Rutherford H. A systematic review on the assessment of pregnancy-specific psychological trauma during pregnancy: A call to action. AJOG Global Reports 2025, 5: 100451. PMID: 40093874, PMCID: PMC11909425, DOI: 10.1016/j.xagr.2025.100451.Peer-Reviewed Original ResearchSystematic reviewPerinatal periodPsychological traumaPreferred Reporting ItemsCare deliveryWeb of ScienceReporting ItemsHealthcare systemIndependent reviewersInfant healthSecondary analysisScreening measuresOvid MEDLINEFull-textOvid EmbaseHistory of traumatic experiencesResearch teamPsychological disordersPerinatal individualsOvidPregnancyTraumatic experiencesTeamTraumaPsycINFOEffects of psychedelics on opioid use disorder: a scoping review of preclinical studies
Pulido-Saavedra A, Oliva H, Prudente T, Kitaneh R, Nunes E, Fogg C, Funaro M, Weleff J, Nia A, Angarita G. Effects of psychedelics on opioid use disorder: a scoping review of preclinical studies. Cellular And Molecular Life Sciences 2025, 82: 49. PMID: 39833376, PMCID: PMC11747050, DOI: 10.1007/s00018-024-05519-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid use disorderUse disorderPreclinical studiesClinical studiesReview of preclinical studiesConditioned place preferenceOpioid self-administrationEffects of psychedelicsPreclinical in vivo studiesOpioid use disorder treatmentFrequency of administrationPlace preferencePotential therapeutic effectsSelf-administrationWithdrawal symptomsPreclinical findingsMechanism of actionSafety profilePain studiesPsychedelicsMethodological quality assessmentClinical evidenceCardiovascular riskOpioidWeb of ScienceA systematic review of variables associated with snakebite risk in spatial and temporal analyses
Collinson S, Lamb T, Cardoso I, Diggle P, Lalloo D. A systematic review of variables associated with snakebite risk in spatial and temporal analyses. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 2025, trae131. PMID: 39817354, DOI: 10.1093/trstmh/trae131.Peer-Reviewed Original ResearchSystematic reviewJoanna Briggs Institute toolHealth facility reportingRisk estimation accuracyWeb of ScienceNarrative synthesisFacility reportsStudy qualityAd hoc surveyResearch availabilityHigh-risk regionsIncidence dataSub-Saharan AfricaUrban residentsGlobal healthPositive associationSnakebite riskInstitutional toolsRisk variationStatistical associationNegative associationSub-SaharanCase incidenceAssociationRiskSystematic Review: Efficacy of Medical Therapy on Outcomes Important to Pediatric Patients With X-Linked Hypophosphatemia
Ali D, Mirza R, Hussein S, Alsarraf F, Alexander R, Abu Alrob H, Appelman-Dijkstra N, Biosse-Duplan M, Brandi M, Carpenter T, Chaussain C, Dandurand K, Filler G, Florenzano P, Fukumoto S, Grasemann C, Imel E, de Beur S, Morgante E, Ward L, Khan A, Guyatt G. Systematic Review: Efficacy of Medical Therapy on Outcomes Important to Pediatric Patients With X-Linked Hypophosphatemia. The Journal Of Clinical Endocrinology & Metabolism 2025, dgaf011. PMID: 39787354, DOI: 10.1210/clinem/dgaf011.Peer-Reviewed Original ResearchX-linked hypophosphatemiaConventional therapyLower limb deformitiesNo treatmentMedical therapyAdverse eventsManagement of "X-linked hypophosphatemiaTreatment-emergent adverse eventsObservational study of individualsObservational studyEfficacy of medical therapyPhysical health QoLAssessed risk of biasBurden of symptomsEffects of medical therapyOpen-label RCTRisk of biasCertainty of evidenceIncreased adverse eventsLimb deformitiesPost hoc studyWeb of ScienceHealth QoLStudy of individualsDental abscessGlobal variation in the assessment of psychological trauma in pregnancy
Wall K, Penner F, Goldman L, Shin J, Novak E, Lowell A, Day M, Papa L, Wright D, Givrad S, Rutherford H. Global variation in the assessment of psychological trauma in pregnancy. Cambridge Prisms Global Mental Health 2025, 12: e10. PMID: 39935728, PMCID: PMC11810758, DOI: 10.1017/gmh.2024.152.Peer-Reviewed Original ResearchSub-Saharan AfricaPregnant peopleSystematic reviewPsychological traumaImpact health outcomesMiddle EastIn-house assessmentPrevalence of traumatic experiencesCulturally appropriate measuresPreferred Reporting ItemsTraumatic experiencesObstetric careWeb of ScienceHealth outcomesCentral AmericaReporting ItemsSecondary analysisOvid MEDLINESub-SaharanOvid EmbaseSystematic literature reviewGeopolitical regionsAssessment of psychological traumaAfricaInterpersonal traumaSocial Determinants of Health and Suicide-Related Outcomes
Na P, Shin J, Kwak H, Lee J, Jester D, Bandara P, Kim J, Moutier C, Pietrzak R, Oquendo M, Jeste D. Social Determinants of Health and Suicide-Related Outcomes. JAMA Psychiatry 2025, 82 PMID: 39745761, DOI: 10.1001/jamapsychiatry.2024.4241.Peer-Reviewed Original ResearchSocial determinants of healthSuicide mortalitySuicide-related outcomesAssociation of social determinants of healthRisk of suicide mortalityPrevent suicideAssociated with suicide mortalitySuicidal ideationHomeless individualsMeta-analysesDeterminants of healthSuicide riskRisk factorsPublic health policiesSuicide attemptsIncarcerated female youthIntimate partner violenceSexual minority statusPrevalence of lifetime suicidal ideationIncreased suicide riskExperiences of childhood abuseSocial determinantsWeb of ScienceResearch SynthesesTailored interventionsThe comparative efficacy and safety of Tiger II versus judkins catheters in coronary angiogram via the radial artery access: a meta-analysis
Aljabali A, Alawajneh M, Hammad A, Nguyen D, Alkasabrah A, Abuein K, Altibi A. The comparative efficacy and safety of Tiger II versus judkins catheters in coronary angiogram via the radial artery access: a meta-analysis. Acta Cardiologica 2025, 80: 39-43. PMID: 39781598, DOI: 10.1080/00015385.2024.2442799.Peer-Reviewed Original ResearchConceptsStandardised mean differenceFluoroscopy timeContrast volumeProcedure timeJudkins catheterOdds ratioProcedural successCoronary angiogramTiger IIEstimates of odds ratiosRadiation exposureMeta-analysisReduced fluoroscopy timeRadial artery vasospasmRandom-effects modelWeb of ScienceRadial artery accessComplication rateArtery vasospasmSecondary outcomesPrimary outcomeComparative efficacyArterial accessTransfemoral accessCochrane Library
2024
Role of Toll-like receptor 2 during infection of Leptospira spp: A systematic review
Kappagoda C, Senavirathna I, Agampodi T, Agampodi S. Role of Toll-like receptor 2 during infection of Leptospira spp: A systematic review. PLOS ONE 2024, 19: e0312466. PMID: 39729468, PMCID: PMC11676585, DOI: 10.1371/journal.pone.0312466.Peer-Reviewed Original ResearchConceptsToll-like receptor 2Toll-like receptor 2 expressionReceptor 2TLR2 responsesSystematic reviewIn vivoImmune effectorsIn vitroEx vivoHuman studiesInvolvement of Toll-like receptor 2Systematic Review Centre for Laboratory Animal Experimentation riskInvolvement of TLR4Increased TLR2 expressionNational Institutes of Health Quality Assessment ToolEffective immune responseIn vitro studiesHuman leptospirosisTLR2 involvementRisk of biasIn vivo studiesTLR2 expressionOffice of Health AssessmentWeb of ScienceImmune responseSystematic Review: Efficacy of Medical Therapy on Outcomes Important to Adult Patients With X-Linked Hypophosphatemia
Ali D, Mirza R, Alsarraf F, Hussein S, Abu Alrob H, Appelman-Dijkstra N, Beck-Nielsen S, Biosse-Duplan M, Brandi M, Carpenter T, Chaussain C, Cohen-Solal M, Crowley R, Dandurand K, Florenzano P, Fukumoto S, Gagnon C, Goodyer P, Grasemann C, Imel E, de Beur S, Lehman A, Lewiecki E, Morgante E, Ward L, Khan A, Guyatt G. Systematic Review: Efficacy of Medical Therapy on Outcomes Important to Adult Patients With X-Linked Hypophosphatemia. The Journal Of Clinical Endocrinology & Metabolism 2024, dgae890. PMID: 39715351, DOI: 10.1210/clinem/dgae890.Peer-Reviewed Original ResearchX-linked hypophosphatemiaConventional therapyPatient-important outcomesNo treatmentModerate certaintyObservational studyAdult patientsManagement of "X-linked hypophosphatemiaEfficacy of medical therapyEffects of burosumabLow certaintyObservational study of individualsHigh-certainty evidenceAssessed risk of biasRisk of biasAbscess riskLow RoB.Medical therapyImprove painPain measuresBurosumabWeb of ScienceGRADE methodologyTherapyEvidence certaintyEffect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis
Hunter C, Marhoffer E, Holleck J, Alshaeba S, Grimshaw A, Chou A, Carey G, Gunderson C. Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis. Journal Of Antimicrobial Chemotherapy 2024, 80: 322-333. PMID: 39656468, DOI: 10.1093/jac/dkae422.Peer-Reviewed Original ResearchPrevalence of P. aeruginosaEffects of empiric antibioticsEmpirical antibioticsUrinary tract infectionSoft tissue infectionsCommunity-acquired pneumoniaTract infectionsTissue infectionsP. aeruginosaMortality benefitHospitalized patientsPseudomonas aeruginosaPooled adjusted ORP. aeruginosa infectionType of infectionStudy of patientsAbsolute mortality benefitIntensive care settingSystematic literature searchNosocomial pneumoniaSeptic shockMeaningful benefitAdjusted ORWeb of ScienceCompare mortality ratesOP09 Investigating The Nature And Scope Of Innovative Payment And Pricing Schemes For Health Technologies
Ardito V, Cavallaro L, Drummond M, Ciani O. OP09 Investigating The Nature And Scope Of Innovative Payment And Pricing Schemes For Health Technologies. International Journal Of Technology Assessment In Health Care 2024, 40: s5-s5. PMCID: PMC11719172, DOI: 10.1017/s0266462324000734.Peer-Reviewed Original ResearchHealth technology assessmentHealth technologiesWeb of ScienceNested evaluationInnovation paymentsSystematic reviewStudy protocolTechnology assessmentHealthImplementation challengesData collection needsAgency websitesExpenditure capsAffordability issuesPayment schemeProduct categoriesPricing schemeDistribution of riskCollection needsPricePROSPEROReimbursementThe effects of a psychoeducational intervention on caregivers of colorectal cancer patients: A meta-analysis of randomized controlled trials
Zhang M, Xue Y, Shao M, Yang Y, Yu L, Ma B, Li D, Zhou H, Wang K, Chen C, Cheng M, Wang T. The effects of a psychoeducational intervention on caregivers of colorectal cancer patients: A meta-analysis of randomized controlled trials. European Journal Of Oncology Nursing 2024, 74: 102739. PMID: 39729814, DOI: 10.1016/j.ejon.2024.102739.Peer-Reviewed Original ResearchConceptsPsychoeducational interventionRandomized controlled trialsPsychological statusImpact of psychoeducational interventionsAspects of caregivingReduce caregiver burdenControlled trialsEnhancing caregivers' abilityCondition of caregiversImprove quality of lifeQuality of lifeCaregiver burdenCRC patientsRandom-effects modelCaregivers' abilityCINAHL CompletePerception of family supportGeneral well-beingActive lifestyleWeb of ScienceMeta-analysis of randomized controlled trialsPhysical healthCare scheduleSocial supportFixed-effects modelPotential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review
Jalilian-Khave L, Kitaneh R, Ysrayl B, Borelli A, Funaro M, Potenza M, Angarita G. Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review. Addiction Neuroscience 2024, 14: 100190. PMID: 40083958, PMCID: PMC11902922, DOI: 10.1016/j.addicn.2024.100190.Peer-Reviewed Original ResearchImpulse control disordersSubstance use disordersControl disordersBehavioral addictionsTreating impulse control disordersVitamin DClinical studiesAddictive disordersSerotonergic circuitsExposure to vitamin DVitamin D deficiencyVitamin D levelsSymptom presenceDisordersPotential beneficial effectsJoanna Briggs InstituteD deficiencyPotential therapeutic mechanismAddictionD levelsWeb of ScienceTherapeutic mechanismQuality of studiesCochrane LibraryOvid MEDLINEHealth‐Related Quality of Life in Women With Metastatic Breast Cancer: An Integrative Review
Zhan Y, Feder S, Lustberg M, Batten J, Knobf M. Health‐Related Quality of Life in Women With Metastatic Breast Cancer: An Integrative Review. Journal Of Advanced Nursing 2024 PMID: 39584570, DOI: 10.1111/jan.16643.Peer-Reviewed Original ResearchHealth-related quality of lifeHealth-related qualityQuality of lifeIntegrative reviewJoanna Briggs Institute appraisal checklistAssess health-related quality of lifeImprove health-related quality of lifeNon-Hispanic white womenImprove health-related qualityBreast cancer experienceFull-text papersBreast cancerProtective factorsCancer experienceIndividualised careSymptom experienceSymptom managementWeb of ScienceAppraisal checklistRacially diverse samplePhysical symptomsReview guidelinesPsychological symptomsMetastatic breast cancerWhite women
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