2025
Connectome-Based Predictive Modeling of PTSD Development Among Recent Trauma Survivors
Ben-Zion Z, Simon A, Rosenblatt M, Korem N, Duek O, Liberzon I, Shalev A, Hendler T, Levy I, Harpaz-Rotem I, Scheinost D. Connectome-Based Predictive Modeling of PTSD Development Among Recent Trauma Survivors. JAMA Network Open 2025, 8: e250331. PMID: 40063028, PMCID: PMC11894499, DOI: 10.1001/jamanetworkopen.2025.0331.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingPosttraumatic stress disorderClinician-Administered PTSD Scale for DSM-5Months post-traumaFunctional magnetic resonance imagingTrauma survivorsDSM-5Post-traumaPosttraumatic stress disorder symptom clustersPosttraumatic stress disorder symptom severityPosttraumatic stress disorder symptom trajectoriesPosttraumatic stress disorder severityTask-based fMRI dataAnterior default modePredictive of symptomsFollow-up assessmentDevelopment of effective personalized treatmentsComprehensive clinical assessmentClinician-AdministeredNeurobiological indicesPosttraumatic psychopathologyHyperarousal symptomsCentral executiveTrauma exposureSalience networkLong-Term Courses of Posttraumatic Growth in Survivors of Hurricane Katrina
Preston J, Lowe S, Rhodes J. Long-Term Courses of Posttraumatic Growth in Survivors of Hurricane Katrina. Traumatology An International Journal 2025, 31: 116-126. DOI: 10.1037/trm0000497.Peer-Reviewed Original ResearchPosttraumatic growthAssociated with membershipIncreased PTGDecreasing PTGPosttraumatic growth trajectoriesPerceived social supportIncreased odds of membershipOdds of membershipStressor scoresPositive religious copingPsychosocial resourcesSocial supportSense of purposeSmall body of literaturePredisaster dataLow-incomeIncreased oddsFactors associated with stabilityBlack mothersReligious copingClinical interventionsTrauma eventsNeighborhood satisfactionSurvivorsTrauma survivors
2024
Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma
Webb E, Stevens J, Ely T, Lebois L, van Rooij S, Bruce S, House S, Beaudoin F, An X, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Swor R, Murty V, Hudak L, Pascual J, Seamon M, Datner E, Pearson C, Peak D, Domeier R, Rathlev N, O’Neil B, Sergot P, Sanchez L, Joormann J, Pizzagalli D, Harte S, Kessler R, Koenen K, Ressler K, McLean S, Harnett N. Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma. JAMA Psychiatry 2024, 81: 1090-1100. PMID: 39083325, PMCID: PMC11292566, DOI: 10.1001/jamapsychiatry.2024.2148.Peer-Reviewed Original ResearchPosttraumatic stress disorder trajectoriesPosttraumatic stress disorderNeural reactivityPTSD trajectoriesTrauma survivorsPosttraumatic stress disorder symptom severityDevelopment of posttraumatic stress disorderResidential greenspaceFunctional magnetic resonance imagingMonetary reward taskReactivity to rewardReward-related regionsCD-RISCCohort studyConnor-Davidson Resilience ScaleParticipant's home addressNeighborhood-level factorsCD-RISC scoreLongitudinal cohort studyReward reactivityReward taskSelf-reported characteristicsStress disorderIndividual-level factorsMultiple ecological levelsSelf-stigma mediates the relationships between childhood maltreatment and symptom levels of PTSD, depression, and anxiety
Haim-Nachum S, Lazarov A, Zabag R, Martin A, Bergman M, Neria Y, Amsalem D. Self-stigma mediates the relationships between childhood maltreatment and symptom levels of PTSD, depression, and anxiety. European Journal Of Psychotraumatology 2024, 15: 2370174. PMID: 38985020, PMCID: PMC11238652, DOI: 10.1080/20008066.2024.2370174.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderChildhood maltreatmentSelf-stigmaChildhood abuseSymptom severity of depressionSymptom typeSubtypes of childhood maltreatmentSurvivors of childhood abuseChildhood trauma survivorsSeverity of depressionChildhood maltreatment experiencesSymptoms of depressionEffects of self-stigmaInternalization of negative stereotypesIncreased self-stigmaMental health problemsSignificant mediation effectAnxiety symptomsStress disorderChildhood neglectSymptom levelsMaltreatment experiencesTrauma survivorsSymptom severityPhysical neglect
2023
Impact of Stress Exposure on Mental and Physical Health across the Life Span: Molecular mechanisms, Neurobiological abnormalities, and Novel Pathways for Intervention
Cattaneo A, Anacker C, Daskalakis N, Riva M. Impact of Stress Exposure on Mental and Physical Health across the Life Span: Molecular mechanisms, Neurobiological abnormalities, and Novel Pathways for Intervention. Psychoneuroendocrinology 2023, 153: 106142. DOI: 10.1016/j.psyneuen.2023.106142.Peer-Reviewed Original ResearchStress exposureEffects of stress exposureImpact of stress exposureSensorimotor gating deficitsChildhood trauma survivorsNegative outcomesPhysical healthEarly life adversityNegative effects of stressExposure to adversityExposure to stressEffects of stressGating deficitsNeurobiological abnormalitiesNeurobiological mechanismsLife stressLife adversityTrauma survivorsSerotonin signalingAffective behaviorNeurodevelopmental windowBrain functionAt adulthoodPhysical diseaseMouse hippocampus
2022
Correction to: When Trauma Survivors with Psychosis Accuse Staff of Sexual Assault in Inpatient Psychiatric Care
Carr E, Sebastian D, Dike C, Hillbrand M. Correction to: When Trauma Survivors with Psychosis Accuse Staff of Sexual Assault in Inpatient Psychiatric Care. Community Mental Health Journal 2022, 59: 420-420. PMID: 36469192, DOI: 10.1007/s10597-022-01064-z.Peer-Reviewed Original ResearchWhen Trauma Survivors with Psychosis Accuse Staff of Sexual Assault in Inpatient Psychiatric Care
Carr ER, Sebastian D, Dike C, Hillbrand M. When Trauma Survivors with Psychosis Accuse Staff of Sexual Assault in Inpatient Psychiatric Care. Community Mental Health Journal 2022, 59: 409-419. PMID: 36301379, DOI: 10.1007/s10597-022-01027-4.Peer-Reviewed Original ResearchConceptsTrauma survivorsSexual assaultMental health servicesTrauma-informed careTraumatic experiencesInpatient psychiatric settingsInformed careAssaultPsychiatric settingsTheoretical frameworkInterdisciplinary teamScant literatureComplex situationsSurvivorsHealth servicesSuch dilemmasClinical skillsSkillsPsychiatric careInpatient settingInpatient psychiatric careUnderstandingPsychosisStaffSettingLongitudinal volumetric evaluation of hippocampus and amygdala subregions in recent trauma survivors
Ben-Zion Z, Korem N, Spiller TR, Duek O, Keynan JN, Admon R, Harpaz-Rotem I, Liberzon I, Shalev AY, Hendler T. Longitudinal volumetric evaluation of hippocampus and amygdala subregions in recent trauma survivors. Molecular Psychiatry 2022, 28: 657-667. PMID: 36280750, PMCID: PMC9918676, DOI: 10.1038/s41380-022-01842-x.Peer-Reviewed Original ResearchConceptsEmergency departmentAmygdala subregionsPTSD diagnosisGeneral hospital emergency departmentLeft amygdala volumeHospital emergency departmentRight hippocampus volumeCA1 hippocampal subregionRecent trauma survivorsTrauma survivorsCivilian trauma survivorsED admissionEligible participantsHippocampus volumeAmygdala volumeHippocampal subregionsVulnerability traitsDisorder pathogenesisClinical InterviewModerate evidenceHippocampus subregionsTrauma exposureStructural MRIRobust evidenceLower initial volumeEPIGENOME-WIDE PREDICTORS OF RESPONSE TO INTERNET-BASED COGNITIVE-BEHAVIORAL THERAPY FOR PTSD IN WORLD TRADE CENTER TRAUMA SURVIVORS
Kozik E, Kowalchyk M, Brinkman H, Desarnaud F, Yehuda R, Pietrzak R, Huckins L, Feder A. EPIGENOME-WIDE PREDICTORS OF RESPONSE TO INTERNET-BASED COGNITIVE-BEHAVIORAL THERAPY FOR PTSD IN WORLD TRADE CENTER TRAUMA SURVIVORS. European Neuropsychopharmacology 2022, 63: e130. DOI: 10.1016/j.euroneuro.2022.07.242.Peer-Reviewed Original ResearchAnxiety sensitivity as a transdiagnostic risk factor for trajectories of adverse posttraumatic neuropsychiatric sequelae in the AURORA study
Short NA, van Rooij SJH, Murty VP, Stevens JS, An X, Ji Y, McLean SA, House SL, Beaudoin FL, Zeng D, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, McGrath ME, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Bruce SE, Pietrzak RH, Joormann J, Barch DM, Pizzagalli DA, Sheridan JF, Smoller JW, Harte SE, Elliott JM, Kessler RC, Koenen KC, Jovanovic T. Anxiety sensitivity as a transdiagnostic risk factor for trajectories of adverse posttraumatic neuropsychiatric sequelae in the AURORA study. Journal Of Psychiatric Research 2022, 156: 45-54. PMID: 36242943, PMCID: PMC10960961, DOI: 10.1016/j.jpsychires.2022.09.027.Peer-Reviewed Original ResearchConceptsAdverse posttraumatic neuropsychiatric sequelaeAnxiety sensitivityTransdiagnostic risk factorWeeks posttraumaPersistent trajectoryPersistent posttraumatic stressElevated anxiety sensitivityTrauma-related symptomsPosttraumatic stress disorderTrauma-related pathologySelf-report assessmentsNeuropsychiatric sequelaeAURORA studyPersonality-related factorsSleep disturbancesGrowth mixture modelingAnxious arousalPosttraumatic stressTrauma survivorsStress disorderBrief interventionPosttrauma periodSomatic symptomsMixture modelingPosttrauma
2021
Factors associated with post-traumatic growth in response to the COVID-19 pandemic: Results from a national sample of U.S. military veterans
Na PJ, Tsai J, Southwick SM, Pietrzak RH. Factors associated with post-traumatic growth in response to the COVID-19 pandemic: Results from a national sample of U.S. military veterans. Social Science & Medicine 2021, 289: 114409. PMID: 34537394, PMCID: PMC8445520, DOI: 10.1016/j.socscimed.2021.114409.Peer-Reviewed Original ResearchConceptsPost-traumatic growthPosttraumatic stress disorderPTSD symptomsU.S. military veteransPositive psychological changesNegative psychological outcomesMilitary veteransU.S. veteransNational samplePrior traumatic eventsAvoidance symptomsTrauma survivorsPsychological outcomesTraumatic eventsPsychological changesPsychosocial interventionsStress disorderPsychological distressPsychological impactCOVID-19 pandemicMajority of researchVeterans StudyMental healthLongitudinal studyFunctional correlatesDrinking to Cope with Posttraumatic Stress: A Nationally Representative Study of Men with and without Military Combat Experience
Blakey SM, Tsai J, Elbogen EB. Drinking to Cope with Posttraumatic Stress: A Nationally Representative Study of Men with and without Military Combat Experience. Journal Of Dual Diagnosis 2021, 17: 101-112. PMID: 33730991, DOI: 10.1080/15504263.2021.1891360.Peer-Reviewed Original ResearchConceptsMilitary combat experiencePosttraumatic stress disorderMilitary combat veteransPTSD symptomsPTSD symptom countCombat experienceHazardous alcohol useAlcohol abuse/dependenceTrauma survivorsAbuse/dependencePTSD diagnosisCombat veteransAlcohol useLifetime trauma exposureSymptom countsTrauma-exposed menLifetime PTSD severityLifetime alcohol abuse/dependenceLifetime PTSD diagnosisLifetime traumatic experiencesFace interview studyMultivariate analysisPosttraumatic stressTrauma exposurePTSD severity
2020
A Life‐Course Model of Trauma Exposure and Mental Health Among Low‐Income Survivors of Hurricane Katrina
Lowe SR, Raker EJ, Arcaya MC, Zacher ML, Waters MC, Rhodes JE. A Life‐Course Model of Trauma Exposure and Mental Health Among Low‐Income Survivors of Hurricane Katrina. Journal Of Traumatic Stress 2020, 33: 950-961. PMID: 32816358, PMCID: PMC7725975, DOI: 10.1002/jts.22581.Peer-Reviewed Original ResearchConceptsPosttraumatic stress symptomsPsychological distressMental healthTrauma exposureNon-Hispanic black mothersPostdisaster mental healthMental health outcomesTime point 1Low-income survivorsLifetime PTERole of exposureNonspecific psychological distressHealth outcomesSymptomsLife course modelSurvivorsLongitudinal studyAssaultive violenceBlack mothersStress symptomsTrauma survivorsExposureTraumatic eventsClinical workHealthTraumatic Stress in Older Adults
Cook J, Simiola V. Traumatic Stress in Older Adults. 2020 DOI: 10.1093/oxfordhb/9780190088224.013.9.Peer-Reviewed Original ResearchPosttraumatic stress disorderAcute stress disorderOlder adultsStress disorderOnset of PTSDAdult trauma survivorsCognitive impairmentTrauma survivorsTraumatic stressMilitary sampleFunctional impairmentAdult civiliansPhysical healthHealthcare utilizationSuicidal ideationSuicide riskImpairmentOlder individualsAdultsGender minoritiesDemographic factorsMental impairmentPrior symptomsDisordersAge groups
2019
T71. Obtaining Neurocognitive Assessments From Trauma Survivors: Feasibility and Lessons Learned From the AURORA Study
Hill M, McGill L, Marginean V, Passell E, Rutter L, Barch D, Joormann J, Stanek J, Soward A, McLean S, Germine L. T71. Obtaining Neurocognitive Assessments From Trauma Survivors: Feasibility and Lessons Learned From the AURORA Study. Biological Psychiatry 2019, 85: s156. DOI: 10.1016/j.biopsych.2019.03.394.Peer-Reviewed Original Research
2018
Do unit and post-deployment social support influence the association between deployment sexual trauma and suicidal ideation?
Monteith LL, Hoffmire CA, Holliday R, Park CL, Mazure CM, Hoff RA. Do unit and post-deployment social support influence the association between deployment sexual trauma and suicidal ideation? Psychiatry Research 2018, 270: 673-681. PMID: 30384288, DOI: 10.1016/j.psychres.2018.10.055.Peer-Reviewed Original ResearchConceptsSuicidal ideationSexual traumaUnit supportPost-deployment supportColumbia-Suicide Severity Rating ScaleLifetime suicide attemptsSeverity Rating ScalePosttraumatic stress disorder (PTSD) symptomsSocial supportSexual trauma survivorsElevated riskPossible depressionSuicide attemptsTraumaRating ScaleDisorder symptomsSocial support influenceIdeationIntensive monitoringTrauma survivorsMenAssociationWomenPresent studySurvey of experiencesPsychiatric and Interpersonal Correlates of Suicide Ideation in Military Sexual Trauma Survivors: The National Health and Resilience in Veterans Study
Monteith LL, Smith NB, Holliday R, Pietrzak RH. Psychiatric and Interpersonal Correlates of Suicide Ideation in Military Sexual Trauma Survivors: The National Health and Resilience in Veterans Study. Chronic Stress 2018, 2: 2470547018815901. PMID: 31218269, PMCID: PMC6583800, DOI: 10.1177/2470547018815901.Peer-Reviewed Original ResearchMilitary sexual traumaMilitary sexual trauma survivorsSexual trauma survivorsHazardous alcohol useSexual traumaPsychological distressInterpersonal correlatesTrauma survivorsAlcohol useGeneral disapprovalSuicidal ideationVeterans StudyWorst traumatic eventSelf-report measuresSuicide attemptsSevere psychological distressWorst traumaInterpersonal responsesTraumatic eventsSocial acknowledgmentCross-sectional designLongitudinal researchSocial supportAlcohol misuseSuicide ideation
2017
The role of evidence-based therapy relationships on treatment outcome for adults with trauma: A systematic review
Ellis AE, Simiola V, Brown L, Courtois C, Cook JM. The role of evidence-based therapy relationships on treatment outcome for adults with trauma: A systematic review. Journal Of Trauma & Dissociation 2017, 19: 185-213. PMID: 28509624, DOI: 10.1080/15299732.2017.1329771.Peer-Reviewed Original ResearchConceptsTrauma survivorsTreatment outcomesAdult trauma survivorsTrauma-related distressEvidence-based therapy relationshipsAllied Health Literature databasesNineteen unique studiesNon-randomized assignmentPsychological treatmentTraumatic stressTherapist trainingRelationship variablesHealth Literature databasesTherapist characteristicsClient engagementTherapeutic allianceTherapy relationshipInclusion criteriaComparison groupCumulative IndexMethodological concernsSystematic reviewClient feedbackComprehensive searchEmpirical literature
2016
A network analysis of DSM-5 posttraumatic stress disorder symptoms and correlates in U.S. military veterans
Armour C, Fried EI, Deserno MK, Tsai J, Pietrzak RH. A network analysis of DSM-5 posttraumatic stress disorder symptoms and correlates in U.S. military veterans. Journal Of Anxiety Disorders 2016, 45: 49-59. PMID: 27936411, DOI: 10.1016/j.janxdis.2016.11.008.Peer-Reviewed Original ResearchConceptsDSM-5 PTSD symptomsTrauma-related emotionsPTSD symptomsDSM-5 posttraumatic stress disorder symptomsPosttraumatic stress disorder (PTSD) symptomsPhysiological cue reactivityMilitary veteran sampleBlame of selfFunctioning/qualityU.S. military veteransSelf-destructive behaviorSuicidal ideationExaggerated startle responseCue reactivityUnderlying common causeTrauma survivorsPartial correlation modelPTSD networkDisorder symptomsPsychological disordersDifferential relationshipsVeteran sampleCentral symptomsDifferential associationsMilitary veteransPrinciples for Recovery-Oriented Inpatient Care
Davidson L, Carr E, Bellamy C, Tondora J, Fossey E, Styron T, Davidson M, Elsamra S. Principles for Recovery-Oriented Inpatient Care. Evidence-Based Practices In Behavioral Health 2016, 39-58. DOI: 10.1007/978-3-319-40537-7_2.Peer-Reviewed Original ResearchRecovery-oriented careInpatient careMental illnessSerious mental illnessOwn recoveryCommunity-based providersHigh prevalenceCare needsInpatient staffInpatient psychiatryCareIllnessTrauma survivorsInterdisciplinary teamFamily membersTraumatic naturePrinciple fourPersonsHospitalizationPrevalenceSurvivorsTraumaRespective rolesRecovery
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