2025
Significance of Coronary Artery Calcifications and Ischemic Electrocardiographic Changes Among Patients Undergoing Myocardial Perfusion Imaging
Kokkinidis D, Kyriakoulis I, Chui P, Agarwal R, Liu Y, Khera R, Sinusas A, Velazquez E, Miller E, Feher A. Significance of Coronary Artery Calcifications and Ischemic Electrocardiographic Changes Among Patients Undergoing Myocardial Perfusion Imaging. JACC Advances 2025, 4: 101618. PMID: 39983619, PMCID: PMC11891677, DOI: 10.1016/j.jacadv.2025.101618.Peer-Reviewed Original ResearchCoronary artery calcificationMyocardial perfusion imagingIschemic ECG changesLow event ratesECG changesNormal perfusionArtery calcificationPerfusion imagingSingle-photon emission computed tomography/computed tomographyStress ECGCAC evaluationPresence of coronary artery calcificationSuspected coronary artery diseaseMedian follow-upEvent ratesIschemic electrocardiographic changesAnalysis to patientsComposite endpoint rateCoronary artery diseaseTomography/computed tomographyPrognostic informationMACE rateFollow-upSubgroup analysisAdverse outcomes
2024
AI-Defined Cardiac Anatomy Improves Risk Stratification of Hybrid Perfusion Imaging
Miller R, Shanbhag A, Killekar A, Lemley M, Bednarski B, Kavanagh P, Feher A, Miller E, Bateman T, Builoff V, Liang J, Newby D, Dey D, Berman D, Slomka P. AI-Defined Cardiac Anatomy Improves Risk Stratification of Hybrid Perfusion Imaging. JACC Cardiovascular Imaging 2024, 17: 780-791. PMID: 38456877, PMCID: PMC11222053, DOI: 10.1016/j.jcmg.2024.01.006.Peer-Reviewed Original ResearchComputed tomography attenuation correctionMajor adverse cardiovascular eventsCoronary artery calciumLV massMyocardial perfusion imagingPerfusion imagingSingle-photon emission computed tomography/computed tomographyIncreased risk of MACEAssociated with major adverse cardiovascular eventsRisk of Major Adverse Cardiovascular EventsCardiac chamber volumesMedian follow-upCT-based volumesRight ventricular volumesImprove cardiovascular risk assessmentAdverse cardiovascular eventsQuartile of LV massContinuous net reclassification indexCoronary artery diseaseNet reclassification indexCardiovascular risk assessmentTomography/computed tomographyConsecutive patientsImprove risk predictionPrognostic utility
2022
Precise characterization of a solitary pulmonary nodule using tumor shadow disappearance rate-corrected F-18 FDG PET and enhanced CT
Park K, Seon H, Yun J, Yoo S, Lee C, Kang S, Kim J, Cho S, Song H, Bom H, Min J, Kwon S. Precise characterization of a solitary pulmonary nodule using tumor shadow disappearance rate-corrected F-18 FDG PET and enhanced CT. Medicine 2022, 101: e28764. PMID: 35119036, PMCID: PMC8812657, DOI: 10.1097/md.0000000000028764.Peer-Reviewed Original ResearchConceptsTumor shadow disappearance rateSolitary pulmonary nodulesF-18 fluorodeoxyglucoseCharacterization of SPNsEnhanced CTPulmonary nodulesTumor areaHigh value of SUVmaxF-18 FDG PETPositron emission tomography/computed tomographyF-18 fluorodeoxyglucose uptakeImaging parametersValue of SUVmaxEmission tomography/computed tomographyStandardized uptake valueTissue densityPost-enhanced CTEnhanced CT imagesPreenhancement CTTomography/computed tomographyChest CTLung windowMediastinal windowUptake valueFDG-PET
2020
Lacrimal sac adenocarcinoma managed with androgen deprivation
Abramson D, Fallon J, Biran N, Francis J, Jaben K, Oh W. Lacrimal sac adenocarcinoma managed with androgen deprivation. American Journal Of Ophthalmology Case Reports 2020, 19: 100607. PMID: 32760849, PMCID: PMC7393461, DOI: 10.1016/j.ajoc.2020.100607.Peer-Reviewed Original ResearchAndrogen deprivation therapyOrbital massAndrogen receptorMagnetic resonance imagingTreatment modalitiesStaging positron emission tomography/computed tomographyExternal beam radiation therapyPositron emission tomography/computed tomographyAndrogen deprivation monotherapyBeam radiation therapyRight orbital massEmission tomography/computed tomographyPrimary surgical managementPrimary treatment modalityEffective treatment modalitySexual side effectsAndrogen deprivationDeprivation therapyMetastatic diseaseTomography/computed tomographyOrbital exenterationRadiation therapyClinical responseInferior rectiPartial resection18 F-fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis of suspected paraneoplastic syndromes: A retrospective analysis
Bresler R, Schroeder H, Chow D, Lim R. 18 F-fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis of suspected paraneoplastic syndromes: A retrospective analysis. World Journal Of Nuclear Medicine 2020, 19: 124-130. PMID: 32939199, PMCID: PMC7478297, DOI: 10.4103/wjnm.wjnm_48_19.Peer-Reviewed Original ResearchF-FDG PET/CTSuspected paraneoplastic syndromeNegative predictive valueParaneoplastic syndromeF-FDGF-fluorodeoxyglucose positron emission tomography/computed tomographyWhole-body <sup>18</sup>F-FDG PET/CTClinical presentation of tumorsPositron emission tomography/computed tomographySingle-center retrospective studyPredictive valueEmission tomography/computed tomographyPresentation of tumorsFollow-up timeElectronic chart reviewPositive predictive valueFollow-up periodSigns and symptomsAncillary diagnostic proceduresDiagnostic imaging toolTomography/computed tomographyF-fluorodeoxyglucoseClinical presentationDiagnostic challengeRetrospective study
2017
Optimization of diagnostic performance for differentiation of recurrence from radiation necrosis in patients with metastatic brain tumors using tumor volume-corrected 11C-methionine uptake
Jung T, Kim I, Lim S, Park K, Kim D, Jung S, Moon K, Jang W, Kang S, Cho S, Min J, Bom H, Kwon S. Optimization of diagnostic performance for differentiation of recurrence from radiation necrosis in patients with metastatic brain tumors using tumor volume-corrected 11C-methionine uptake. EJNMMI Research 2017, 7: 45. PMID: 28536967, PMCID: PMC5442037, DOI: 10.1186/s13550-017-0293-0.Peer-Reviewed Original ResearchMetabolic tumor volumeMetastatic brain tumorsGamma knife radiosurgeryT/N ratioCutoff valueRadiation necrosisDiagnostic performanceReceiver operating characteristicBrain tumorsDiagnostic accuracyPositron emission tomography/computed tomographyEmission tomography/computed tomographyDiagnosis of recurrenceRatio cutoff valueDifferentiation of recurrenceOptimal cutoff valueNormal tissue ratiosSmall-sized lesionsTomography/computed tomographyRecurrent lesionsTumor volumePET/CTDifferential diagnosisTumorT/NApplication of a Novel CD206+ Macrophage-Specific Arterial Imaging Strategy in HIV-Infected Individuals
Zanni M, Toribio M, Wilks M, Lu M, Burdo T, Walker J, Autissier P, Foldyna B, Stone L, Martin A, Cope F, Abbruzzese B, Brady T, Hoffmann U, Williams K, El-Fakhri G, Grinspoon S. Application of a Novel CD206+ Macrophage-Specific Arterial Imaging Strategy in HIV-Infected Individuals. The Journal Of Infectious Diseases 2017, 215: 1264-1269. PMID: 28204544, PMCID: PMC5853590, DOI: 10.1093/infdis/jix095.Peer-Reviewed Original ResearchMeSH KeywordsAortaAtherosclerosisCase-Control StudiesCross-Sectional StudiesDextransHIV InfectionsHumansLectins, C-TypeLymph NodesMacrophagesMaleMannansMannose ReceptorMannose-Binding LectinsMiddle AgedPlaque, AtheroscleroticRadiopharmaceuticalsReceptors, Cell SurfaceRegression AnalysisSingle Photon Emission Computed Tomography Computed TomographyTechnetium Tc 99m PentetateUnited StatesConceptsSingle-photon emission computed tomography/computed tomographyFirst-in-human dataNon-HIV-infected subjectsAortic plaque volumeHIV-infected subjectsHIV-infected individualsMacrophages ex vivoComputed tomographic angiographyCD206+ macrophagesTomography/computed tomographyTomographic angiographyImaging techniquesTechnetium TcHIV statusPlaque volumeCardiovascular diseaseHIVImaging strategiesCD206In vivo applicationsSubjectsTilmanoceptAngiographyMacrophagesTomography
2016
Giant Cell Tumor with Secondary Aneurysmal Bone Cyst Shows Heterogeneous Metabolic Pattern on 18F-FDG PET/CT: A Case Report
Park H, Kwon S, Cho S, Kim J, Song H, Kim S, Yoon Y, Park J. Giant Cell Tumor with Secondary Aneurysmal Bone Cyst Shows Heterogeneous Metabolic Pattern on 18F-FDG PET/CT: A Case Report. Nuclear Medicine And Molecular Imaging 2016, 50: 348-352. PMID: 27994691, PMCID: PMC5135695, DOI: 10.1007/s13139-016-0423-z.Peer-Reviewed Original ResearchSecondary aneurysmal bone cystGiant cell tumorAneurysmal bone cystCystic componentCell tumorsMaximum standardized uptake valuePositron emission tomography/computed tomographyBone cystCase of giant cell tumorEmission tomography/computed tomographyStandardized uptake valueAneurysmal bone cyst componentMetabolic patternsBenign bone tumorsLeft proximal femurPrimary bone neoplasmsHypermetabolic lesionsTomography/computed tomographyFluorodeoxyglucose uptakeUptake valueCase reportPET/CTBone neoplasmsBone tumorsBenign nature
2014
[18F]-Fluoromisonidazole Positron Emission Tomography/Computed Tomography Visualization of Tumor Hypoxia in Patients With Chordoma of the Mobile and Sacrococcygeal Spine
Cheney M, Chen Y, Lim R, Winrich B, Grosu A, Trofimov A, Depauw N, Shih H, Schwab J, Hornicek F, DeLaney T. [18F]-Fluoromisonidazole Positron Emission Tomography/Computed Tomography Visualization of Tumor Hypoxia in Patients With Chordoma of the Mobile and Sacrococcygeal Spine. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: 1030-1036. PMID: 25539367, PMCID: PMC4280072, DOI: 10.1016/j.ijrobp.2014.08.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCell HypoxiaChordomaFeasibility StudiesFemaleHumansMaleMiddle AgedMisonidazoleMultimodal ImagingNeoplasm Recurrence, LocalPhotonsPilot ProjectsPositron-Emission TomographyProspective StudiesProton TherapyRadiopharmaceuticalsRadiotherapy DosageRelative Biological EffectivenessSacrococcygeal RegionSpinal NeoplasmsTomography, X-Ray ComputedTumor BurdenConceptsHypoxic subvolumesGross tumor volumeFMISO PET/CTRadiation therapyLocal recurrenceTumor volumeSacrococcygeal spinePositron emission tomography/computed tomographyRT dose escalationStage T2 tumorsEmission tomography/computed tomographyStandardized uptake valueMedian follow-upTreatment of chordomasChanges to treatmentVisualization of tumor hypoxiaDose escalationT2 tumorsTomography/computed tomographyMetastatic diseaseRecurrent chordomaUptake valueClinical characteristicsTumor hypoxiaFollow-up
2013
Myocardial Blood Flow and Flow Reserve in Proximal and Mid-to-Distal Lesions of Left Anterior Descending Artery Measured By N-13 Ammonia PET/CT
Cho S, Kim J, Cho J, Kim H, Bom H. Myocardial Blood Flow and Flow Reserve in Proximal and Mid-to-Distal Lesions of Left Anterior Descending Artery Measured By N-13 Ammonia PET/CT. Nuclear Medicine And Molecular Imaging 2013, 47: 158-165. PMID: 24900102, PMCID: PMC4035192, DOI: 10.1007/s13139-013-0208-6.Peer-Reviewed Original ResearchLeft anterior descending arteryMyocardial blood flowAnterior descending arteryCoronary artery diseasePerfusion defectsMid-anterior segmentLAD territoryDescending arteryArea involvementPositron emission tomography/computed tomographyFlow reserveResting myocardial blood flowEmission tomography/computed tomographyBlood flowLocation of stenotic lesionsGlobal MFRTomography/computed tomographyN-13Proximal lesionsArtery diseasePET/CTStenotic lesionsRegional myocardial blood flowPurposeThe purposeLesions
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