2025
Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern.
Kiriakopoulos E, Chu F, Salpekar J, Baslet G, Ghearing G, Altalib H, Sajatovic M. Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern. Epilepsy Currents 2025, 15357597251318577. PMID: 40028187, PMCID: PMC11869224, DOI: 10.1177/15357597251318577.Peer-Reviewed Original ResearchPsychosocial burdenSelf-harmPublic health concernEvidence-based suicide prevention strategiesHealth concernSuicide prevention strategiesSocial stressorsHigh riskGlobal public health concernMultidisciplinary cliniciansSuicide preventionPrevention strategiesGeneral populationAdjunctive supportSuicide riskIncreased riskIdentification of patientsEarly identificationSuicideBurdenRiskFunctional seizuresPeoplePatient subpopulationsPsychosocialChronotherapeutic intervention targeting emotion regulation brain circuitry, symptoms, and suicide risk in adolescents and young adults with bipolar disorder: a pilot randomised trial
Kim J, Sankar A, Marks R, Carrubba E, Lecza B, Quatrano S, Spencer L, Constable R, Pittman B, Lebowitz E, Silverman W, Swartz H, Blumberg H. Chronotherapeutic intervention targeting emotion regulation brain circuitry, symptoms, and suicide risk in adolescents and young adults with bipolar disorder: a pilot randomised trial. BMJ Mental Health 2025, 28: e301338. PMID: 39971594, PMCID: PMC11840897, DOI: 10.1136/bmjment-2024-301338.Peer-Reviewed Original ResearchConceptsBipolar disorderEmotion regulationSuicide riskBrain circuitryChronotherapeutic interventionsEmotional face stimuliLeft amygdala responseRisk of bipolar disorderTargeting emotion regulationReduce suicide riskHigher suicide riskYoung adultsFunctional MRI dataPost-treatment improvementAmygdala responsePotential intervention targetsEmotion dysregulationMania symptomsMood episodesFace stimuliCircuitry dysfunctionRegulation therapyDaily rhythmsWeekly sessionsSelf-monitoringLUMATEPERONE TREATMENT FOR MAJOR DEPRESSIVE EPISODES WITH MIXED FEATURES IN MAJOR DEPRESSIVE DISORDER AND BIPOLAR I OR BIPOLAR II DISORDER
Bhagwagar *, Kozauer S, Earley W, Chen C, Huo J, Stahl S, McIntyre R, Durgam S. LUMATEPERONE TREATMENT FOR MAJOR DEPRESSIVE EPISODES WITH MIXED FEATURES IN MAJOR DEPRESSIVE DISORDER AND BIPOLAR I OR BIPOLAR II DISORDER. The International Journal Of Neuropsychopharmacology 2025, 28: i19-i19. PMCID: PMC11815047, DOI: 10.1093/ijnp/pyae059.033.Peer-Reviewed Original ResearchBipolar depressionBipolar II disorderII disorderLumateperone treatmentMDD populationBipolar IDSM-5Baseline to dayDSM-5-TRIncreased suicide riskMixing featuresPoor treatment responseAdverse eventsMADRS totalTreatment-emergent adverse eventsCGI-S scoresHypomanic symptomsDepressive disorderExtrapyramidal symptomsTreat schizophreniaDepressive episodeConsistent with prior studiesLumateperoneSuicide riskMDDOpen Access: Dissociation in suicidal depression: a Reformulated Object-Relations Theory (RORT) perspective
Shahar G, Robison M, Joiner T. Open Access: Dissociation in suicidal depression: a Reformulated Object-Relations Theory (RORT) perspective. 2025, 198-226. DOI: 10.4324/9781003560616-9.Peer-Reviewed Original ResearchInterpersonal-psychological theory of suicidal behaviorTheory of suicidal behaviorDepressive positionInterpersonal-psychological theoryObject-relations theoryMelanie Klein's notionFailed belongingnessSuicidal behaviorSuicidal depressionInterpersonal strifeSuicide riskTrauma-basedMental representationsInterpersonal actionsMental processesCase illustrationSuicideKill oneselfKlein's notionBasic-levelDissociative structureDepressionAffectBelongingnessAdulthoodEmulating a randomized clinical trial with real-world data to evaluate the effect of antidepressant use in PTSD patients with high suicide risk
Miranda O, Qi X, Brannock M, Whitworth R, Kosten T, Ryan N, Haas G, Kirisci L, Wang L. Emulating a randomized clinical trial with real-world data to evaluate the effect of antidepressant use in PTSD patients with high suicide risk. Frontiers In Psychiatry 2025, 15: 1526488. PMID: 39935628, PMCID: PMC11811752, DOI: 10.3389/fpsyt.2024.1526488.Peer-Reviewed Original ResearchPost-traumatic stress disorderSuicide-related eventsPost-traumatic stress disorder patientsPost-traumatic stress disorder populationEffects of antidepressant useIncreased risk of suicideInitiation of antidepressantsRisk of suicideStress disorderSuicide riskAntidepressant useAntidepressantsBehavioral changesSuicideLoss to follow-upRandomized clinical trialsMultiple comparisonsTreatment cessationFollow-upClinical trialsIncreased riskElevated riskPatientsCitalopramVenlafaxineAddressing Suicide Risk in Autistic Youth: A Preliminary Study of Pediatric Emergency Medicine Physician Attitudes
Cervantes P, Richards-Rachlin S, Seag D, Conlon G, Donnelly L, Lee M, Shalev R, Tay E, Knapp K, Wiener E, Baroni A, Horwitz S. Addressing Suicide Risk in Autistic Youth: A Preliminary Study of Pediatric Emergency Medicine Physician Attitudes. Journal Of Developmental And Physical Disabilities 2025, 1-12. DOI: 10.1007/s10882-025-10006-y.Peer-Reviewed Original ResearchEmergency departmentSuicide-related careAutistic youthManaging suicide riskPediatric emergency medicineSuicide riskEmergency department providersSuicide risk identificationNon-autistic youthSuicide prevention practicesSuicide risk assessmentPhysicians' attitudesPhysician trainingEmergency medicinePrevention practicesPsychiatric concernsYouth suicideSuicidal thoughtsPatient populationProvidersPhysiciansConfidenceSuicideYouthTrainingPredictive Validity and Treatment Sensitivity of the Death-Implicit Association Test (D-IAT) During Inpatient Treatment and Across a 6-Month Follow-Up Period
Levy H, Lord K, Rice T, Sain K, Stubbing J, Diefenbach G, Tolin D. Predictive Validity and Treatment Sensitivity of the Death-Implicit Association Test (D-IAT) During Inpatient Treatment and Across a 6-Month Follow-Up Period. Cognitive Therapy And Research 2025, 1-10. DOI: 10.1007/s10608-024-10564-z.Peer-Reviewed Original ResearchDeath Implicit Association TestSuicidal thoughtsInpatient treatmentFrequency of suicidal behaviorAssociation TestCognitive-behavioral therapyHigh risk of suicidePsychiatric inpatient unitTreatment sensitivitySample of inpatientsRisk of suicideImplicit cognitionSuicidal behaviorSuicide riskPredictive validitySuicide preventionDetect treatment effectsInpatient unitSuicideFollow-up periodPeriod post-dischargeInpatientsTreatment effectsThoughtsInpatient admissionsResilience and Vulnerability: Suicide-Specific Cognitions in a Nationally Representative Sample of US Military Veterans.
Fischer I, Nichter B, Trachik B, Bryan C, Pietrzak R. Resilience and Vulnerability: Suicide-Specific Cognitions in a Nationally Representative Sample of US Military Veterans. The Primary Care Companion For CNS Disorders 2025, 27 PMID: 39823445, DOI: 10.4088/pcc.24m03821.Peer-Reviewed Original ResearchConceptsSuicide-specific cognitionsNationally representative sampleUS military veteransSuicide riskMilitary veteransActivities of daily livingNational Health and ResilienceSample of US military veteransSuicide Cognitions ScalePrevalence of veteransPositive psychological traitsReduce suicide riskAdverse childhood experiencesDaily livingPsychosocial characteristicsSocial supportVeterans StudyUS veteransSuicidal behaviorSuicidal ideationCognitive scalesRepresentative samplePsychological traitsElevated riskSocial connectednessThe Promise of a Retreat: Perspectives of U.S. Women Veterans and Interdisciplinary Experts on the Development of a Retreat-Based Suicide Prevention Program for Violence-Exposed Women Veterans.
Presseau C, Walls S, Murray-Swank N, Portnoy G, Decker S, Kroll-Desrosiers A, Martino S. The Promise of a Retreat: Perspectives of U.S. Women Veterans and Interdisciplinary Experts on the Development of a Retreat-Based Suicide Prevention Program for Violence-Exposed Women Veterans. Violence Against Women 2025, 10778012241303471. PMID: 39763454, DOI: 10.1177/10778012241303471.Peer-Reviewed Original ResearchSuicide prevention programsWomen veteransPrevention programsMental health programsVeterans Health AdministrationPrevention program componentsSemi-structured interviewsHealth programsHolistic healthHealth AdministrationProgram facilitatorsFocus groupsEmergent themesViolence-exposedProgram preferencesSuicide riskProgram componentsPrevention strategiesVeteransInterdisciplinary expertsSubject matter expertsSocial connectionsWomenMatter expertsProgramSocial Determinants of Health and Suicide-Related Outcomes
Na P, Shin J, Kwak H, Lee J, Jester D, Bandara P, Kim J, Moutier C, Pietrzak R, Oquendo M, Jeste D. Social Determinants of Health and Suicide-Related Outcomes. JAMA Psychiatry 2025, 82 PMID: 39745761, DOI: 10.1001/jamapsychiatry.2024.4241.Peer-Reviewed Original ResearchSocial determinants of healthSuicide mortalitySuicide-related outcomesAssociation of social determinants of healthRisk of suicide mortalityPrevent suicideAssociated with suicide mortalitySuicidal ideationHomeless individualsMeta-analysesDeterminants of healthSuicide riskRisk factorsPublic health policiesSuicide attemptsIncarcerated female youthIntimate partner violenceSexual minority statusPrevalence of lifetime suicidal ideationIncreased suicide riskExperiences of childhood abuseSocial determinantsWeb of ScienceResearch SynthesesTailored interventions
2024
Suicide Risk Among Veterans Who Receive Evidence-Based Therapy for Posttraumatic Stress Disorder
Saulnier K, Brabbs S, Szymanski B, Harpaz-Rotem I, McCarthy J, Sripada R. Suicide Risk Among Veterans Who Receive Evidence-Based Therapy for Posttraumatic Stress Disorder. JAMA Network Open 2024, 7: e2452144. PMID: 39724372, PMCID: PMC11672158, DOI: 10.1001/jamanetworkopen.2024.52144.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationPosttraumatic stress disorder diagnosisVeterans Health Administration carePosttraumatic stress disorderSuicide riskStress disorderAdequate courseDeath certificate dataAssociated with lower suicide riskCohort study of veteransMortality Data RepositoryPopulation-based sampleStudy of veteransLower suicide riskReceipt of evidence-based treatmentsEvidence-based psychotherapiesMultivariable proportional hazards regressionProportional hazards regressionEvidence-based treatmentsAssociated with suicideEvidence-based therapiesCertificate dataSuicide mortalityHealth AdministrationMain OutcomesBrief Cognitive Behavioral Therapy for Suicidal Inpatients
Diefenbach G, Lord K, Stubbing J, Rudd M, Levy H, Worden B, Sain K, Bimstein J, Rice T, Everhardt K, Gueorguieva R, Tolin D. Brief Cognitive Behavioral Therapy for Suicidal Inpatients. JAMA Psychiatry 2024, 81: 1177-1186. PMID: 39259550, PMCID: PMC11391362, DOI: 10.1001/jamapsychiatry.2024.2349.Peer-Reviewed Original ResearchBrief cognitive behavioral therapyCognitive behavioral therapySubstance use disordersSuicidal ideationBehavioral therapySuicide attemptsFollow-up assessmentUse disorderOccurrence of suicide attemptsPsychiatric readmissionRates of psychiatric readmissionSuicide prevention treatmentsEffect of treatment conditionPrivate psychiatric hospitalTreatment effectsSuicidal inpatientsSuicide riskSuicidal crisisPsychiatric hospitalIndividual sessionsIdeationSuicide reattemptsPost hoc analysisSelf-reportBlinded interviewersTrauma-related nightmares among U.S. veterans: Findings from a nationally representative study
Worley C, Meshberg-Cohen S, Fischer I, Pietrzak R. Trauma-related nightmares among U.S. veterans: Findings from a nationally representative study. Sleep Medicine 2024, 126: 159-166. PMID: 39672095, DOI: 10.1016/j.sleep.2024.11.031.Peer-Reviewed Original ResearchTrauma-related nightmaresNationally representative sampleSuicidal ideationTreatment of trauma-related nightmaresRepresentative sampleAssociated with adverse mental healthExposure to adverse childhood eventsTrauma-exposed veteransAssociated with elevated oddsAdverse mental healthIncreased suicide riskNationally representative studyAdverse childhood eventsUS military veteransTransdiagnostic assessmentNightmare severityTrauma exposureHealth historySociodemographic factorsMental healthSuicide riskTrauma typesPsychiatric conditionsSociodemographic characteristicsPsychosocial functioningStrategic Treatment and Assessment for Youth (STAY): A Theoretically-Driven, Culturally-Tailored MBC Approach
Arora P, Awad M, Parr K, Connors E. Strategic Treatment and Assessment for Youth (STAY): A Theoretically-Driven, Culturally-Tailored MBC Approach. Administration And Policy In Mental Health And Mental Health Services Research 2024, 52: 261-276. PMID: 39541064, PMCID: PMC11703679, DOI: 10.1007/s10488-024-01419-6.Peer-Reviewed Original ResearchMeasurement-based careREM youthTreatment retentionDepressive symptomsTheoretically-drivenImprove treatment retentionAlliance measuresBarriers to treatmentPremature dropoutSuicide riskSuicidal thoughtsTreatment engagementREM populationsFeedback processesClient outcomesTreatment expectationsREMWhite peersSuicideYouthCultural competency trainingCompetency trainingSymptomsTreatment assessmentDepressionAssociation of holidays and the day of the week with suicide risk: multicountry, two stage, time series study
Lee W, Kang C, Park C, Bell M, Armstrong B, Roye D, Hashizume M, Gasparrini A, Tobias A, Sera F, Honda Y, Urban A, Kyselý J, Íñiguez C, Ryti N, Guo Y, Tong S, de Sousa Zanotti Stagliorio Coelho M, Lavigne E, de'Donato F, Guo Y, Schwartz J, Schneider A, Breitner S, Chung Y, Kim S, Ha E, Kim H, Kim Y, Network M, Jaakkola J, Matus P, Ortega N, Orru H, Indermitte E, Michelozzi P, Vicedo-Cabrera A, Ragettli M, Pan S, Kan H, Seposo X, Masselot P, Li S, Huang W, Diaz M, De la Cruz Valenci C, Holobaca I, Scovronick N, Acquaotta F, Zanobetti A, Dang T, Saldiva P. Association of holidays and the day of the week with suicide risk: multicountry, two stage, time series study. The BMJ 2024, 387: e077262. PMID: 39442941, PMCID: PMC11497772, DOI: 10.1136/bmj-2024-077262.Peer-Reviewed Original ResearchThe association of pain screening and pain level with suicide among US veterans with comorbid musculoskeletal and bipolar disorder diagnoses
Abel E, Travaglini L, Snow J, Goulet J. The association of pain screening and pain level with suicide among US veterans with comorbid musculoskeletal and bipolar disorder diagnoses. Journal Of Affective Disorders 2024, 369: 429-435. PMID: 39389110, DOI: 10.1016/j.jad.2024.10.028.Peer-Reviewed Original ResearchVeterans Health AdministrationBipolar disorder diagnosisPain screeningPain severity ratingsMusculoskeletal disordersSuicide mortalityPain severityRelative risk of suicideDisorder diagnosisVHA databaseMusculoskeletal disorder diagnosisSuicide riskActual medication useAssociation of painSuicide prevention effortsRisk of suicideHighest suicide ratesHigher suicide riskSuicide risk factorsRetrospective cohort studySubstance use disordersHealth AdministrationPain diagnosisPoisson regressionUS veteransW15. A MULTIVARIATE GENOMIC INVESTIGATION OF THE EXTERNALIZING SPECTRUM AND SUICIDE RISK
Barr P, Bigdeli T, Sanchez-Roige S, Mallard T, Ashley-Koch A, Dick D, Harden P, Hauser B, Qin X, Aslan M, Harvey P, Beckham J, Kimbrel N. W15. A MULTIVARIATE GENOMIC INVESTIGATION OF THE EXTERNALIZING SPECTRUM AND SUICIDE RISK. European Neuropsychopharmacology 2024, 87: 108. DOI: 10.1016/j.euroneuro.2024.08.224.Peer-Reviewed Original ResearchSuicide attemptsSuicidal ideationPolygenic scoresAssociated with suicide attemptsGenomic structural equation modelingLifetime suicide riskRisk factors associated with suicideExternalizing polygenic scoresLifetime suicide attemptsSubstance use disordersFactors associated with suicideSubstance-use behaviorsExternalizing spectrumExternalizing disordersBipolar disorderPsychiatric diagnosisSuicide riskStructural equation modelingResults Preliminary resultsSuicidal phenotypeGenome-wide association studiesPersonality indicesIdeationSuicideCohort of veteransGambling and Substance Use Disorders in U.S. Military Veterans: Prevalence, Clinical Characteristics, and Suicide Risk
Stefanovics E, Potenza M, Tsai J, Pietrzak R. Gambling and Substance Use Disorders in U.S. Military Veterans: Prevalence, Clinical Characteristics, and Suicide Risk. Journal Of Gambling Studies 2024, 40: 2119-2139. PMID: 39342537, DOI: 10.1007/s10899-024-10359-7.Peer-Reviewed Original ResearchSubstance use disordersU.S. military veteransMental health treatmentGambling groupSUD-onlySuicide riskHealth treatmentMilitary veteransNon-suicidal self-injuryLifetime substance use disorderNational Health and ResilienceRisk of substance use disordersSUD-only groupSelf-report measuresMental health difficultiesAdverse childhood experiencesMental health burdenPast-year gamblingSelf-injurySuicidality/self-harmVeterans StudyUse disorderNicotine dependenceTrauma variablesBehavioral correlatesAssociation between cognitive functioning, suicidal ideation and suicide attempts in major depressive disorder, bipolar disorder, schizophrenia and related disorders: A systematic review and meta-analysis
Le G, Wong S, Haikazian S, Johnson D, Badulescu S, Kwan A, Gill H, Di Vincenzo J, Rosenblat J, Mansur R, Teopiz K, Rhee T, Ho R, Liao S, Cao B, Schweinfurth-Keck N, Vinberg M, Grande I, Phan L, d'Andrea G, McIntyre R. Association between cognitive functioning, suicidal ideation and suicide attempts in major depressive disorder, bipolar disorder, schizophrenia and related disorders: A systematic review and meta-analysis. Journal Of Affective Disorders 2024, 365: 381-399. PMID: 39168166, DOI: 10.1016/j.jad.2024.08.057.Peer-Reviewed Original ResearchBipolar disorderCognitive functionSchizoaffective disorderDepressive disorderExecutive functionMental disordersMeasures of cognitive functionSelf-injurious behaviorTreatable mental disorderGlobal executive functioningEffect size of associationSuicidal ideation/suicide attemptTransdiagnostic associationsSize of associationEmotional inhibitionWorking memoryNegative associationCognitive measuresNeurocognitive deficitsSuicidal ideationSuicide riskCognitive disturbancesImpulse controlProcessing speedMDDRole of homelessness and psychiatric disorders in suicide deaths among veterans: A four-way decomposition analysis
Beydoun H, Szymkowiak D, Pietrzak R, Beydoun M, Treadwell R, Tsai J. Role of homelessness and psychiatric disorders in suicide deaths among veterans: A four-way decomposition analysis. Psychiatry Research 2024, 340: 116120. PMID: 39121758, DOI: 10.1016/j.psychres.2024.116120.Peer-Reviewed Original ResearchMental health disordersFour-way decomposition analysisSubstance useHealth disordersPsychiatric disordersMortality riskSuicide deathsHomeless veteransVeterans AffairsSubstance use disordersU.S. Department of Veterans AffairsDepartment of Veterans AffairsPredictors of suicide deathVA healthcare systemFully-adjusted modelsMental health characteristicsEffects of homelessnessProportion of suicide deathsSuicide riskUse disorderHealth characteristicsRetrospective cohort studySuicideHealthcare systemDisorders
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply