2025
Decreasing inappropriate MRCP with contrast exams: impact of an EMR-Embedded clinical care pathway
Asch D, Gunabushanam G, Cole K, Holland C, Pahade J. Decreasing inappropriate MRCP with contrast exams: impact of an EMR-Embedded clinical care pathway. Abdominal Radiology 2025, 1-8. PMID: 40439723, DOI: 10.1007/s00261-025-05022-7.Peer-Reviewed Original ResearchPlan-Do-Study-ActClinical care pathwayCare pathwaysClinical appropriatenessPlan-do-study-act cycle 1Clinical guidanceElectronic medical recordsReduce healthcare costsChi-square testHealthcare costsEmergency departmentMedical recordsResultsAt baselinePatient characteristicsAppropriate ordersStudy periodResource useProvidersStatistical significanceBaselineExamAppropriatenessIV contrastIntravenous contrastGadolinium exposureThe implementation of artificial intelligence in serial monitoring of post gamma knife vestibular schwannomas: A pilot study
Singh M, Jester N, Lorr S, Briano A, Schwartz N, Mahajan A, Chiang V, Tommasini S, Wiznia D, Buono F. The implementation of artificial intelligence in serial monitoring of post gamma knife vestibular schwannomas: A pilot study. Clinical Imaging 2025, 123: 110495. PMID: 40388858, DOI: 10.1016/j.clinimag.2025.110495.Peer-Reviewed Original ResearchConceptsGamma knife radiosurgeryVestibular schwannomaPost-GKSTumor growthVS volumeHalting tumor growthRetrospective cohort studyAssess treatment efficacyManual segmentationHearing lossBenign tumorsPaired t-testT1-weighted MRI scansAssess statistical significanceCohort studyDice similarity coefficientNeurological functionTreatment efficacyClinical monitoringMRI scansStatistical significancePercentage changeSchwannomaSpatial overlapTumorAdherence to SVS Abdominal Aortic Aneurysm Guidelines Among Patients Detected by AI-Based Algorithm
Wilson E, Yao K, Kostiuk V, Bader J, Loh S, Mojibian H, Fischer U, Ochoa Chaar C, Aboian E. Adherence to SVS Abdominal Aortic Aneurysm Guidelines Among Patients Detected by AI-Based Algorithm. Annals Of Vascular Surgery 2025, 120: 108-114. PMID: 40349830, DOI: 10.1016/j.avsg.2025.05.007.Peer-Reviewed Original ResearchAbdominal aortic aneurysmAdherent patientsSurgical interventionAbdominal aortic aneurysm patientsNon-adherent patientsTertiary care centerFollow-up adherenceFollow-up algorithmSVS guidelinesImaging surveillanceSurgical criteriaAneurysm sizeAortic aneurysmIdentified patientsPati entsSurveillance adherenceVascular providersImaging scansDeceased patientsPatientsPhysician evaluationCare centerPatient outcomesStatistical significanceNo significant age differencesTiming of depression in relation to risk of ovarian cancer
Roberts A, Townsend M, Chibnik L, Kubzansky L, Tworoger S. Timing of depression in relation to risk of ovarian cancer. Journal Of The National Cancer Institute 2025, 117: 989-996. PMID: 39745894, PMCID: PMC12058258, DOI: 10.1093/jnci/djae348.Peer-Reviewed Original ResearchRisk of ovarian cancerAssociation of depressionAscertainment periodIncident cancerAssociated with greater cancer riskAssociated with increased risk of ovarian cancerAssociated with elevated riskTime of depressionAssociated with increased riskP-value thresholdCox proportional hazards modelsCancer ascertainmentProportional hazards modelCancer riskTests of statistical significanceStatistical significanceExamined depressionOvarian cancerElevated riskProspective cohortBehavioral factorsAscertainmentHazards modelConsecutive two-year periodDepression
2024
Ectopic pregnancy is associated with increased risk of displaced implantation window: a retrospective study
Zeng H, Chang Y, Liu N, Li S. Ectopic pregnancy is associated with increased risk of displaced implantation window: a retrospective study. BMC Pregnancy And Childbirth 2024, 24: 839. PMID: 39707276, PMCID: PMC11661333, DOI: 10.1186/s12884-024-07072-z.Peer-Reviewed Original ResearchConceptsAssisted reproductive technologyBody mass indexAssociated with increased riskPrimary infertilityEmbryo transferEctopic pregnancy historyEctopic pregnancyReproductive Medicine CenterRetrospective studyStatistical significanceGeneralized estimating equationsInfertility typeHigher body mass indexReproductive technologySecondary infertilityInfertilityPregnancy historyImplantation windowImplant failureMass indexXiangya HospitalAdvanced ageIncreased riskPatientsPregnancyThe Incidence and Significance of Iliac Vein Stenosis in Patients with Deep Vein Thrombosis
Ali S, Chan S, Brahmandam A, Xu Y, Deng Y, Elbadawy A, Lee A, Ochoa Chaar C. The Incidence and Significance of Iliac Vein Stenosis in Patients with Deep Vein Thrombosis. Annals Of Vascular Surgery 2024, 111: 310-318. PMID: 39617297, DOI: 10.1016/j.avsg.2024.11.016.Peer-Reviewed Original ResearchIliac vein stenosisIpsilateral DVT recurrenceCross-sectional imagingDVT recurrenceVein stenosisMedical records of consecutive adult patientsRecords of consecutive adult patientsSubgroup analysisPrevention of pulmonary embolismDevelopment of DVTConsecutive adult patientsIncidence of PEDeep vein thrombosisGroup of patientsLower extremity DVTRecurrent DVTPulmonary embolismVein thrombosisBaseline characteristicsRetrospective studyAdult patientsDVTPatientsElectronic medical recordsStatistical significanceTrends in Medicare Reimbursement and Service Volume of Vitreoretinal Procedures: 2000 to 2021
Li E, Adelman R. Trends in Medicare Reimbursement and Service Volume of Vitreoretinal Procedures: 2000 to 2021. Journal Of VitreoRetinal Diseases 2024, 9: 31-36. PMID: 39539838, PMCID: PMC11556364, DOI: 10.1177/24741264241292743.Peer-Reviewed Original ResearchVitreoretinal proceduresStatistically significant decreasePanretinal photocoagulation treatmentInflation-adjusted Medicare reimbursementSignificant decreaseSpearman correlationMedicare Part B National Summary Data FilesScleral bucklingEvaluate time trendsIntravitreal injectionPhotocoagulation treatmentNational reimbursement ratesSpearman correlation coefficientPractice patternsPatient coverageMedicare Physician Fee ScheduleStatistical significancePhysician Fee ScheduleMedicare reimbursementSignificant declineReimbursement ratesInjectionReimbursement trendsTime trendsIntravitrealClinical outcomes among patients with mitral valve regurgitation undergoing Impella-supported high-risk PCI
Abu-Much A, Grines C, Chen S, Batchelor W, Zhao D, Falah B, Maini A, Redfors B, Bellumkonda L, Bharadwaj A, Moses J, Truesdell A, Zhang Y, Zhou Z, Baron S, Lansky A, Basir M, O'Neill W, Cohen D. Clinical outcomes among patients with mitral valve regurgitation undergoing Impella-supported high-risk PCI. International Journal Of Cardiology 2024, 417: 132555. PMID: 39270940, DOI: 10.1016/j.ijcard.2024.132555.Peer-Reviewed Original ResearchLower left ventricular ejection fractionMitral valve regurgitationPercutaneous coronary interventionHigh-risk PCISevere MRHigh-risk percutaneous coronary interventionMR severityPCI-related complicationsValve regurgitationIII studiesHeart failureAssociated with worse outcomesPrevalence of heart failurePresence of severe MRLower body mass indexVentricular ejection fractionStatistical significanceHigh-risk PCI patientsBody mass indexTrace MREjection fractionModerate MRClinical outcomesMild MRWorse outcomesParental Binge Eating and Child Binge Eating and Weight‐Control Behaviors: Cross‐Sectional and Longitudinal Findings From the EAT 2010–2018 Study
Lydecker J, Zhang Z, Larson N, Loth K, Wall M, Neumark‐Sztainer D. Parental Binge Eating and Child Binge Eating and Weight‐Control Behaviors: Cross‐Sectional and Longitudinal Findings From the EAT 2010–2018 Study. International Journal Of Eating Disorders 2024, 57: 2260-2268. PMID: 39219404, PMCID: PMC11560518, DOI: 10.1002/eat.24284.Peer-Reviewed Original ResearchWeight control behaviorsBinge eatingProject F-EATChildren of parentsTime 1F-EATYoung adulthoodPopulation-based sampleRisk factorsWeight controlElevated riskStatistical significanceEating psychopathologyYoung adult childrenBingeRetrospective researchEatingLongitudinal findingsChildren's useChild genderAdolescent childrenChildrenPsychopathologyAdulthoodAdolescentsFeasibility of In-Hospital Administration of a Tool to Predict Persistent Post-ICU Functional Impairment Among Older ICU Survivors A Pilot Study
Stevenson J, Murphy T, Tessier-Sherman B, Pisani M, Gill T, Ferrante L. Feasibility of In-Hospital Administration of a Tool to Predict Persistent Post-ICU Functional Impairment Among Older ICU Survivors A Pilot Study. CHEST Critical Care 2024, 2: 100093. PMID: 39822381, PMCID: PMC11737545, DOI: 10.1016/j.chstcc.2024.100093.Peer-Reviewed Original ResearchRisk prediction toolsICU survivorsIn-hospital administrationOlder adultsFunctional impairmentPilot studyIn-hospital mobilityOlder ICU survivorsDevelopment of risk prediction modelsHospital-related factorsIn-hospital factorsPresence of deliriumRisk prediction modelModel discriminationPersistent functional impairmentStatistical significanceHospital settingStudy designFeasibility thresholdDaily activitiesIncreased riskInternational Consensus ConferenceConsensus conferenceSurvivorsCritical illnessP-543 Multicenter concordance study of embryo cell-free DNA and trophectoderm biopsies: impact on clinical outcomes
Sánchez L, Sakkas D, Frantz N, Soscia D, Venier B, Bisioli C, DiMattina M, Ozturk B, Barroso G, Escudero E, De la Fuente E, Valbuena D, Simon C, Rubio C. P-543 Multicenter concordance study of embryo cell-free DNA and trophectoderm biopsies: impact on clinical outcomes. Human Reproduction 2024, 39: deae108.882. DOI: 10.1093/humrep/deae108.882.Peer-Reviewed Original ResearchSingle embryo transferTE biopsy resultsCell-free DNATrophectoderm biopsyMiscarriage rateBiopsy resultsClinical outcomesChi-square testNon-invasive preimplantation genetic testingFrozen single embryo transferInner cell mass biopsiesStatistical significanceCell-free DNA analysisDecrease miscarriage ratesPGT-A cyclesPreimplantation genetic testingDroplet of culture mediumLocal institutional review boardAssisted reproduction centerBiopsied blastocystsNiPGT-ATE biopsyEuploid embryosBlastocyst biopsyBlastocyst mediumP101 Sustained improvement in atopic dermatitis disease control and treatment satisfaction with dupilumab in clinical practice: 4-year follow-up results from the RELIEVE-AD study
Wang Z, Yang M, Chao J, Martins B, Chuang C, Shumel B, Sierka D, Carboni M, Strober B. P101 Sustained improvement in atopic dermatitis disease control and treatment satisfaction with dupilumab in clinical practice: 4-year follow-up results from the RELIEVE-AD study. British Journal Of Dermatology 2024, 191: i63-i64. DOI: 10.1093/bjd/ljae090.128.Peer-Reviewed Original ResearchAtopic dermatitisEpisodes of itchingTreatment satisfactionMonth 1Disease controlClinical practiceProportion of patientsPatient survey studyPercentage of patientsSustained improvementFollow-up resultsPrescribed dupilumabGeneralized estimating equationsQuality of lifePatient support programmeSingle-armDupilumabSkin symptomsBaseline surveyPatientsSupport programmesPatient satisfactionPractice guidelinesStatistical significanceMonthsPrenatal arsenic metabolite exposure is associated with increased newborn mitochondrial DNA copy number: evidence from a birth cohort study
Qiu F, Zhang H, Wang X, Jia Z, He Y, Wu Y, Li Z, Zheng T, Xia W, Xu S, Li Y. Prenatal arsenic metabolite exposure is associated with increased newborn mitochondrial DNA copy number: evidence from a birth cohort study. Environmental Science And Pollution Research 2024, 31: 38142-38152. PMID: 38789711, DOI: 10.1007/s11356-024-32933-7.Peer-Reviewed Original ResearchDNA copy numberThird trimesterUrinary arsenic species concentrationsNewborn mitochondrial DNA copy numberMother-newborn pairsDose-response trendMitochondria DNA copy numberReal-time polymerase chain reactionBirth cohort studyMetabolite exposureCopy numberMitochondrial DNA copy numberOne-unit incrementCovariate-adjusted modelsBlood mtDNAcnQuantitative real-time polymerase chain reactionPolymerase chain reactionCohort studyTrimesterMetabolite levelsPotential associationStatistical significanceArsenic metabolitesChain reactionMtDNAcnIncreased Patient Engagement with Utilization of Online Cryomanagement Platform
Lynch C, Pandolfi E, Walimbe P, Ng C, Gonsalez S, Desai V. Increased Patient Engagement with Utilization of Online Cryomanagement Platform. Reproductive BioMedicine Online 2024, 48: 104062. DOI: 10.1016/j.rbmo.2024.104062.Peer-Reviewed Original ResearchA Quantitative Examination of Illness Models Among People With Opioid Use Disorder Receiving Methadone Treatment
Gazzola M, Carmichael I, Thompson E, Beitel M, Madden L, Saeed G, Hoffman K, Hammouri M, Hsaio C, Barry D. A Quantitative Examination of Illness Models Among People With Opioid Use Disorder Receiving Methadone Treatment. Journal Of Addiction Medicine 2024, 18: 262-268. PMID: 38446859, DOI: 10.1097/adm.0000000000001282.Peer-Reviewed Original ResearchBrain disease modelMethadone treatmentTreatment beliefsIllness modelAssociated with beliefsOpioid use disorderUse disorderOutpatient opioid treatment programAddiction modelTreatment programsOpioid treatment programsAddictionMethadoneMultivariate analysisScale agreementIllnessDisordersCounselingBrainBeliefsDisease modelsOpioidPatientsStatistical significanceMultivariate regressionThe International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groups in the Forthcoming (Ninth) Edition of the TNM Classification for Lung Cancer
Rami-Porta R, Nishimura K, Giroux D, Detterbeck F, Cardillo G, Edwards J, Fong K, Giuliani M, Huang J, Kernstine K, Marom E, Nicholson A, Van Schil P, Travis W, Tsao M, Watanabe S, Rusch V, Asamura H, Boards A. The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groups in the Forthcoming (Ninth) Edition of the TNM Classification for Lung Cancer. Journal Of Thoracic Oncology 2024, 19: 1007-1027. PMID: 38447919, DOI: 10.1016/j.jtho.2024.02.011.Peer-Reviewed Original ResearchClassification of lung cancerLung cancerTNM classificationStage groupSignificance of survival differencesInternational Association for the Study of Lung CancerLung Cancer Staging ProjectTNM stage groupingTNM classification of lung cancerStudy of Lung CancerEdition TNMStage NSCLCPathological stageClinical stageSurvival differencesAnatomic extentTNMSurvival analysisTreatment approachesCancerStatistical significanceMultivariate regressionPatientsLungFruquintinib plus paclitaxel versus paclitaxel as second-line therapy for patients with advanced gastric or gastroesophageal junction adenocarcinoma (FRUTIGA): A randomized, multicenter, double-blind, placebo-controlled, phase 3 study.
Xu R, Wang F, Shen L, Guo W, Liu T, Li J, Qin S, Bai Y, Chen Z, Wang J, Pan Y, Shu Y, Zhao F, Cheng Y, Ye F, Gu K, Zhang T, Pan H, Zhong H, Su W. Fruquintinib plus paclitaxel versus paclitaxel as second-line therapy for patients with advanced gastric or gastroesophageal junction adenocarcinoma (FRUTIGA): A randomized, multicenter, double-blind, placebo-controlled, phase 3 study. Journal Of Clinical Oncology 2024, 42: 438780-438780. DOI: 10.1200/jco.2024.42.36_suppl.438780.Peer-Reviewed Original ResearchPhase 3 studyAntitumor therapyMedian OSDouble-blindPrimary endpointInhibitor of VEGFR-1Dose of study drugSecond-line treatment optionDual primary endpointsPlacebo (PBO)-controlledFirst-line chemotherapyGastroesophageal junction adenocarcinomaMetastatic colorectal cancerSecond-line therapyLymph node metastasisTreatment of paclitaxelStatistical significanceCox proportional hazards modelsPost hoc analysisOral inhibitorJunction adenocarcinomaEligible ptsPlacebo-controlledStudy drugStatistically significant improvement
2023
Obexelimab in Systemic Lupus Erythematosus With Exploration of Response Based on Gene Pathway Co‐Expression Patterns: A Double‐Blind, Randomized, Placebo‐Controlled, Phase 2 Trial
Merrill J, Guthridge J, Smith M, June J, Koumpouras F, Machua W, Askanase A, Khosroshahi A, Sheikh S, Rathi G, Burington B, Foster P, Matijevic M, Arora S, Wang X, Gao M, Wax S, James J, Zack D. Obexelimab in Systemic Lupus Erythematosus With Exploration of Response Based on Gene Pathway Co‐Expression Patterns: A Double‐Blind, Randomized, Placebo‐Controlled, Phase 2 Trial. Arthritis & Rheumatology 2023, 75: 2185-2194. PMID: 37459248, DOI: 10.1002/art.42652.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusLoss of improvementPrimary endpointLupus erythematosusWeek 32B cellsEfficacy-evaluable populationImproved disease activityPhase 2 trialProportion of patientsTreatment-related toxicityTreatment of patientsPlacebo-ControlledCorticosteroid injectionDisease activityInfusion reactionsTrough concentrationsPatient subsetsPlasma cellsPatientsSecondary analysisMonoclonal antibodiesStatistical significanceEndpointPlaceboPerformance and reliability assessment of a lower dose, task-based scoliosis radiography protocol in pediatric patients
Al-Dasuqi K, Taylor E, Ehrlich L, Cooperman D, Socci A, Tuason D, Hoerner M, Staib L, Silva C. Performance and reliability assessment of a lower dose, task-based scoliosis radiography protocol in pediatric patients. Pediatric Radiology 2023, 54: 146-153. PMID: 38010426, DOI: 10.1007/s00247-023-05812-5.Peer-Reviewed Original ResearchConceptsDose area productPatient heightAdequate image qualityEffective doseExposure indexMedian effective doseLower radiation exposureComparison of proportionsChi-squared testIntraclass correlation coefficientBland-Altman plotsConsecutive patientsPediatric patientsIncident air kermaDose reductionLow doseSkeletal maturityRadiographsPatientsAir kermaRadiation exposureScoliosis radiographyStatistical significanceDoseSpinal curvatureOrthopedic Sub-Specialties Vary in Representation of Female Fellowship Program Directors
Fram B, Kazley J, Cannada L. Orthopedic Sub-Specialties Vary in Representation of Female Fellowship Program Directors. Journal Of Orthopaedic Experience & Innovation 2023, 4 DOI: 10.60118/001c.75452.Peer-Reviewed Original ResearchFemale program directorsProgram director genderFellowship program directorsProgram directorsFellowship positionsDirector genderFemale representationOrthopedic oncologyWomen's decisionsH-indicesMethods DataOrthopedic subspecialtiesLow female representationPediatric orthopedicsStatistical significanceFellowship programsProgram dataFemale leadershipSub-specialtySubspecialtyAcademic rankSubspecialitiesDirectorsP-valueTraining positions
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