2025
A series of hydroxychloroquine-associated cardiotoxicity presenting with heart failure
Nazarenko N, Maliha M, Parker M, Borkowski P, Csecs I, Tauras J, Julia Shin J, Pullman J, Sims D, Rochlani Y. A series of hydroxychloroquine-associated cardiotoxicity presenting with heart failure. Annals Of Medicine And Surgery 2025, 87: 1334-1340. DOI: 10.1097/ms9.0000000000002997.Peer-Reviewed Original ResearchSystemic lupus erythematosusHCQ useHeart failureCardiac abnormalitiesCardiac magnetic resonance imagingDose-dependent complicationsRheumatoid arthritisCases of SLE patientsDiscontinuation of hydroxychloroquineResolution of symptomsLong-term therapyEarly detectionShortness of breathA-V blockHCQ therapyMagnetic resonance imagingPrompt discontinuationEndomyocardial biopsyPulmonary hypertensionEjection fractionHF therapyCardiac symptomsImprove patient outcomesSLE patientsSjogren's syndromeSalivary gland stem/progenitor cells: advancing from basic science to clinical applications
Langthasa J, Guan L, Jinagal S, Le Q. Salivary gland stem/progenitor cells: advancing from basic science to clinical applications. Cell Regeneration 2025, 14: 4. PMID: 39856475, PMCID: PMC11759724, DOI: 10.1186/s13619-025-00221-5.Peer-Reviewed Original ResearchSalivary gland stem/progenitor cellsBioengineered organ replacementTissue-based therapiesEffective clinical therapiesRadiation therapySjogren's syndromeStem/progenitor cellsClinical therapyTherapyDifferentiation pathwayClinical applicationRegenerative medicineSyndromeTissue regenerationOrgan replacementCulture techniquesSjogrenTransplantationPatients
2024
Mixed and undifferentiated autoimmune connective tissue diseases
Vesely M. Mixed and undifferentiated autoimmune connective tissue diseases. Clinics In Dermatology 2024 PMID: 39681290, DOI: 10.1016/j.clindermatol.2024.12.011.Peer-Reviewed Original ResearchConnective tissue diseaseTissue diseaseCutaneous manifestationsUndifferentiated connective tissue diseaseAutoimmune connective tissue diseaseEra of molecular diagnosticsSigns of systemic diseaseUrticarial vasculitisSystemic complicationsSjogren's syndromeClinical entityDescription of patientsSystemic diseaseClinical observationsDisease characterizationMolecular diagnosticsDiseasePatientsVasculitisDisorders with Ophthalmic and Thoracic Involvement.
Gosangi B, Lang P, Johnson M, Zukerman R, Tu L, Traube L, Bader A, Rubinowitz A. Disorders with Ophthalmic and Thoracic Involvement. RadioGraphics 2024, 44: e230132. PMID: 38870047, DOI: 10.1148/rg.230132.Peer-Reviewed Original ResearchConceptsClinical manifestationsExamination of family membersEhlers-Danlos syndromeAffecting patient outcomesAcute sarcoidosisOphthalmologic examinationThoracic symptomsDry eyeThoracic involvementOphthalmological symptomsOphthalmologic manifestationsEye symptomsMarfan syndromeSjogren's syndromeImaging findingsRadiological studiesLung diseasePatient outcomesEhlers-DanlosFamily membersMultimodal imagingSystem conditionsSyndromeThoracicSarcoidosisParasympathetic neurons derived from human pluripotent stem cells model human diseases and development
Wu H, Saito-Diaz K, Huang C, McAlpine J, Seo D, Magruder D, Ishan M, Bergeron H, Delaney W, Santori F, Krishnaswamy S, Hart G, Chen Y, Hogan R, Liu H, Ivanova N, Zeltner N. Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development. Cell Stem Cell 2024, 31: 734-753.e8. PMID: 38608707, PMCID: PMC11069445, DOI: 10.1016/j.stem.2024.03.011.Peer-Reviewed Original ResearchConceptsAutonomic nervous systemSjogren's syndromeParasympathetic neuronsFamilial dysautonomiaWhite adipocytesAutoimmune disease Sjogren's syndromeHuman pluripotent stem cellsHuman pluripotent stem cell (hPSC)-derived neuronsHuman developmental studiesPluripotent stem cellsSARS-CoV-2 infectionSchwann cell progenitorsAutonomic neuropathyCell progenitorsStem cellsModel systemNervous systemSARS-CoV-2Human diseasesDysfunctionNeuronsDifferentiation paradigmOrgan developmentNeuropathyDrug discovery studiesChapter 6 The eye and the microbiome
Raolji S, Lai J, Watane A, Goodman C, Chipkin B, Galor A. Chapter 6 The eye and the microbiome. 2024, 229-262. DOI: 10.1016/b978-0-323-90144-4.00006-9.Peer-Reviewed Original Research
2023
Coexistent Sjogren’s syndrome and Birt-Hogg-Dube´ syndrome: a case report
Lin Y, Guo T, Lei C, Yang B, Yang D, Luo H, Peng H. Coexistent Sjogren’s syndrome and Birt-Hogg-Dube´ syndrome: a case report. BMC Pulmonary Medicine 2023, 23: 460. PMID: 37993820, PMCID: PMC10664354, DOI: 10.1186/s12890-023-02680-5.Peer-Reviewed Original ResearchConceptsSjogren's syndromeBirt-HoggMultiple thin-walled cystic lesionsDiffuse cystic lung diseasesThin-walled cystic lesionsShortness of breathCystic lung diseaseLabial gland biopsyDry eyeLower lungCystic changesCystic lesionsLung diseasePhysical examinationCase reportGland biopsyDube syndromeRare caseComputed tomographyDubé syndromeInsufficient evidenceSyndromeDiagnostic algorithmLungRespiratory sounds
2022
Severe extra-glandular involvement and pleural effusions complicating primary Sjogren’s syndrome: a case report
Abou Ziki M, Taoutel R, Hong J, Podell D. Severe extra-glandular involvement and pleural effusions complicating primary Sjogren’s syndrome: a case report. Journal Of Medical Case Reports 2022, 16: 374. PMID: 36253840, PMCID: PMC9578189, DOI: 10.1186/s13256-022-03557-7.Peer-Reviewed Original ResearchConceptsPrimary Sjogren's syndromeSjogren's syndromePleural effusionKeratoconjunctivitis siccaMonoclonal gammopathyDisease severityB-cell non-Hodgkin lymphomaExtra-glandular involvementBilateral pleural effusionLymphocytic interstitial pneumoniaEvidence of malignancyMulti-organ diseaseSevere multi-organ diseaseAnti-Ro antibodiesNon-Hodgkin lymphomaMultiple organ systemsSevere bronchiectasisRare complicationInterstitial pneumoniaBenign diseaseAutoimmune diseasesDental cariesCase reportCaucasian womenSkin ulcersICOS Gene Polymorphisms (IVS1 + 173 T/C and c. 1624 C/T) in Primary Sjögren’s Syndrome Patients: Analysis of ICOS Expression
García-Espinoza J, Muñoz-Valle J, García-Chagollán M, Hernández-Bello J, Palafox-Sánchez C, López-Villalobos E, Sánchez-Zuno G, Martínez-Bonilla G, Cerpa-Cruz S, Carrillo-Ballesteros F, Oregon-Romero E. ICOS Gene Polymorphisms (IVS1 + 173 T/C and c. 1624 C/T) in Primary Sjögren’s Syndrome Patients: Analysis of ICOS Expression. Current Issues In Molecular Biology 2022, 44: 764-776. PMID: 35723338, PMCID: PMC8929044, DOI: 10.3390/cimb44020053.Peer-Reviewed Original ResearchPrimary Sjogren's syndrome patientsPrimary Sjogren's syndromeLymphocytic infiltrationT cellsControl subjectsSusceptibility to primary Sjogren's syndromePathogenesis of primary Sjogren's syndromeMRNA expressionICOS gene polymorphismsICOS+ T cellsAssociated with lymphocytic infiltrationSjogren's syndrome patientsHigh lymphocytic infiltrationT cell subsetsSystemic autoimmune diseaseT cell activationICOS expressionSjogren's syndromeC polymorphismGene polymorphismsReal-time PCRSyndrome patientsAutoimmune diseasesImmune responseFlow cytometry
2021
Enfermedades reumáticas y alergias, la dualidad del sistema inmunológico
Sánchez-Zuno G, Oregón-Romero E, Hernández-Bello J, González-Estevez G, Vargas-Rosales R, Muñoz-Valle J. Enfermedades reumáticas y alergias, la dualidad del sistema inmunológico. Revista Alergia México 2021, 68: 264-275. PMID: 34904562, DOI: 10.29262/ram.v68i4.984.Peer-Reviewed Original Research
2015
Cervicofacial necrotizing fasciitis caused by Haemophilus influenzae serotype e in a patient with Sjogren's syndrome, systemic lupus erythematosus and hypocomplementaemia
Azar M, Folk D, Henderson T, Mehra S, Vining E, Banach D. Cervicofacial necrotizing fasciitis caused by Haemophilus influenzae serotype e in a patient with Sjogren's syndrome, systemic lupus erythematosus and hypocomplementaemia. JMM Case Reports 2015, 2 DOI: 10.1099/jmmcr.0.000040.Peer-Reviewed Case Reports and Technical NotesSystemic lupus erythematosusNecrotizing fasciitisH. influenzaeSjogren's syndromeLupus erythematosusInvasive diseaseHaemophilus influenzae serotype eInvasive H. influenzae infectionsSerotype E.Cervicofacial necrotizing fasciitisMonomicrobial necrotizing fasciitisCervical necrotizing fasciitisH. influenzae infectionsBroad-spectrum antibioticsAdditional debridementB vaccinationEmergent debridementNeck painInfluenzae infectionIntraoperative culturesBlood culturesClinical dataImmunocompromised individualsFasciitisClinical importance
2012
Altered Th17 and Th1 cells responses in patients with primary Sjogren syndrome (59.10)
Kang G, Kim S, Bunin V, Shin M, Lee N, Parke A, Kang I. Altered Th17 and Th1 cells responses in patients with primary Sjogren syndrome (59.10). The Journal Of Immunology 2012, 188: 59.10-59.10. DOI: 10.4049/jimmunol.188.supp.59.10.Peer-Reviewed Original ResearchPrimary Sjogren's syndromeHealthy subjectsIL-7IL-17IL-23Sjogren's syndromeIL-10IL-12Peripheral bloodIL-1βIL-6Th1 cellsTh1-polarizing cytokine IL-12Anti-inflammatory cytokine IL-10Frequencies of Th17Frequency of CD4Cytokine IL-10IL-10 productionSystemic autoimmune diseaseCytokines IL-12IL-12 productionInnate immune cellsMajor proinflammatory cytokineSupernatants of lipopolysaccharideDry mouth
2002
A Case of Bronchus-Associated Lymphoid Tissue(BALT) Lymphoma in the Lung of the Patient with Primary Sjogren's Syndrome
Kang M, Lee J, Lee S, Son J, Kim D, Lee M, Hyun I, Jung K. A Case of Bronchus-Associated Lymphoid Tissue(BALT) Lymphoma in the Lung of the Patient with Primary Sjogren's Syndrome. Tuberculosis And Respiratory Diseases 2002, 52: 179-185. DOI: 10.4046/trd.2002.52.2.179.Peer-Reviewed Original ResearchPrimary Sjogren's syndromeSjogren's syndromeOpen lung biopsy specimenB-cell lymphoma originatingThin-section CT scansCD 20 antigenAnti-nuclear antibodiesWhole lung fieldMalignant lymphoma cellsBALT lymphomaInspiratory cracklesReticulonodular densitiesDry mouthExertional dyspneaLymphoma originatingDry eyeHistological diagnosisHistological findingsLung zonesPhysical examinationBasal lungBiopsy specimenBronchiolar epitheliumChest radiographsLung fields
1989
The Ro ribonucleoprotein particle: Induction of autoantibodies and the detection of Ro RNAs among species
Mamula M, O'Brien C, Harley J, Hardin J. The Ro ribonucleoprotein particle: Induction of autoantibodies and the detection of Ro RNAs among species. Clinical Immunology 1989, 52: 435-446. PMID: 2503280, DOI: 10.1016/0090-1229(89)90158-x.Peer-Reviewed Original ResearchConceptsRo RNAsInduction of autoantibodiesSystemic lupus erythematosusRo particleAnti-Ro autoantibodiesCell linesRabbit cell linesSjogren's syndromeLupus erythematosusHuman autoimmune seraRo seraImmune responseHigh titersAutoantibodiesAutoimmune seraSerumRabbit serumSolid-phase assaysRabbit antibodiesHuman cellsImmunodiffusion studiesSyndromeBovine cell linesTissue extractsPrecipitin line
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