2024
Renovascular hypertension – a primer for the radiologist
Dixe de Oliveira Santo I, Sindoni J, Czeyda-Pommersheim F, Solomon N, Sailer A, Bhatt S, Fananapazir G, Pellerito J, Revzin M. Renovascular hypertension – a primer for the radiologist. Abdominal Radiology 2024, 1-13. PMID: 39542950, DOI: 10.1007/s00261-024-04677-y.Peer-Reviewed Original ResearchRenovascular hypertensionRenal arteryCause of renovascular hypertensionComputed tomography angiographyMagnetic resonance angiographyDiagnosing RVHExtrinsic compressionSecondary hypertensionRare conditionImaging findingsPolyarteritis nodosaSurgical interventionFibromuscular dysplasiaAnatomical variantsPage kidneyPictorial reviewHypertension casesAccurate diagnosisMedical managementDiagnostic criteriaTreatment approachesImaging modalitiesHypertensionImpact diagnosisYoung femalesA Curriculum on Advanced Topics in Hypertension for Internal Medicine Residents
Gallagher B, Windish D. A Curriculum on Advanced Topics in Hypertension for Internal Medicine Residents. Southern Medical Journal 2024, 117: 556-561. PMID: 39227050, DOI: 10.14423/smj.0000000000001732.Peer-Reviewed Original ResearchInternal medicine residentsMedicine residentsRepeated-measures analysis of varianceChronic kidney diseaseSmall group sessionsRepeated-measures analysisMean confidence scoreHypertensive urgencySecondary hypertensionKidney diseaseHypertensionUS adultsImmediate postMulti-institutional surveyResident confidenceHypertension expertsPostcurriculum surveysOutpatient settingPostcurriculumPrecurriculumHalf-dayTime pointsWeeksTraining scoresAnalysis of variance
2023
Does This Child With High Blood Pressure Have Secondary Hypertension?
Nugent J, Jiang K, Funaro M, Saran I, Young C, Ghazi L, Bakhoum C, Wilson F, Greenberg J. Does This Child With High Blood Pressure Have Secondary Hypertension? JAMA 2023, 329: 1012-1021. PMID: 36976276, DOI: 10.1001/jama.2023.3184.Peer-Reviewed Original ResearchConceptsBlood pressure loadAmbulatory blood pressure monitoringSecondary hypertensionBlood pressure monitoringPrimary hypertensionFamily historyBlood pressurePressure monitoringDiastolic blood pressure loadSystolic blood pressure loadSerum uric acid concentrationAmbulatory blood pressureHigh blood pressureHistory of prematurityPrimary care clinicsRisk of biasNumber of patientsDatabases of MEDLINEDiagnostic Accuracy Studies toolLower body weightRandom-effects modelingUric acid concentrationWeb of ScienceLikelihood ratioAsymptomatic presentation
2022
Prevalence of Secondary Hypertension in Otherwise Healthy Youths with a New Diagnosis of Hypertension: A Meta-Analysis
Nugent JT, Young C, Funaro MC, Jiang K, Saran I, Ghazi L, Wilson FP, Greenberg JH. Prevalence of Secondary Hypertension in Otherwise Healthy Youths with a New Diagnosis of Hypertension: A Meta-Analysis. The Journal Of Pediatrics 2022, 244: 30-37.e10. PMID: 35120981, PMCID: PMC9086113, DOI: 10.1016/j.jpeds.2022.01.047.Peer-Reviewed Original ResearchConceptsSecondary hypertensionPrimary careLow prevalenceNew diagnosisTime of diagnosisClinical practice guidelinesCochrane Library databasesBlood pressure deviceSignificant subgroup differencesParticipants' age rangeWeb of ScienceHypertension definitionReferral clinicProspective studyRetrospective studyOutpatient settingHealthy childrenSecondary causesCurrent guidelinesDiagnostic evaluationHypertensionObservational studyPractice guidelinesLibrary databasesPrevalence estimates9 Systemic and pulmonary arterial hypertension
Selzer A, Fontes M, Heerdt P. 9 Systemic and pulmonary arterial hypertension. 2022, 187-202. DOI: 10.1016/b978-0-323-71860-8.00018-5.Peer-Reviewed Original ResearchPulmonary artery pressurePulmonary hypertensionSystemic hypertensionArterial pressurePrevalence of pulmonary arterial hypertensionDiagnosis of pulmonary hypertensionSixth World SymposiumRight heart catheterizationPulmonary arterial hypertensionAmerican College of Cardiology/American Heart AssociationPharmacological treatment modalitiesPrimary systemic hypertensionSystolic blood pressureHeart catheterizationPerioperative morbidityThoracic surgeryArterial hypertensionSecondary hypertensionAdult patientsTreatment modalitiesWorld SymposiumMm HgPerioperative implicationsHeart AssociationPostoperative phase
2015
Novel somatic mutations in primary hyperaldosteronism are related to the clinical, radiological and pathological phenotype
Scholl UI, Healy JM, Thiel A, Fonseca AL, Brown TC, Kunstman JW, Horne MJ, Dietrich D, Riemer J, Kücükköylü S, Reimer EN, Reis AC, Goh G, Kristiansen G, Mahajan A, Korah R, Lifton RP, Prasad ML, Carling T. Novel somatic mutations in primary hyperaldosteronism are related to the clinical, radiological and pathological phenotype. Clinical Endocrinology 2015, 83: 779-789. PMID: 26252618, PMCID: PMC4995792, DOI: 10.1111/cen.12873.Peer-Reviewed Original ResearchConceptsAldosterone-producing adenomaAdrenal hyperplasiaHyperplastic adrenal glandsUnilateral adrenal hyperplasiaClinical pathological featuresBilateral adrenal hyperplasiaSomatic mutationsNovel somatic mutationsPredominant histologySecondary hypertensionPrimary hyperaldosteronismRetrospective studyAdrenal glandPathological characteristicsMale genderClear cellsCACNA1D mutationsComputed tomographyImportant causeTumorsKCNJ5HyperplasiaAdenomasExome sequencingPathological phenotypes
2008
A Novel Form of Human Mendelian Hypertension Featuring Nonglucocorticoid-Remediable Aldosteronism
Geller DS, Zhang J, Wisgerhof MV, Shackleton C, Kashgarian M, Lifton RP. A Novel Form of Human Mendelian Hypertension Featuring Nonglucocorticoid-Remediable Aldosteronism. The Journal Of Clinical Endocrinology & Metabolism 2008, 93: 3117-3123. PMID: 18505761, PMCID: PMC2515083, DOI: 10.1210/jc.2008-0594.Peer-Reviewed Original ResearchConceptsGlucocorticoid-remediable aldosteronismAdrenal fasciculataAdministration of dexamethasoneAdrenal steroid productionAdrenal steroid biosynthesisNew familial formAge 7 yrSecondary hypertensionBilateral adrenalectomyMost patientsPrimary aldosteronismAdrenal weightClinical syndromeAdrenal glandCortisol secretionLeading causeAldosteronismHypertensionMedical treatmentAldosterone synthaseSteroid productionAutosomal dominant formCellular hypertrophyCortical compartmentFamilial forms
1997
Hypertension and hypokalemia: unusual syndromes.
Cruz D, Perazella M. Hypertension and hypokalemia: unusual syndromes. Connecticut Medicine 1997, 61: 67-75. PMID: 9066195.Peer-Reviewed Original ResearchConceptsSecondary hypertensionMedical historyApparent mineralocorticoid excess syndromeAdrenal enzyme defectsAssociation of hypertensionHigh-renin statesLow renin stateMineralocorticoid excess stateMineralocorticoid excess syndromeCases of hypertensionRenal potassium wastingPatient's medical historyPrimary hyperaldosteronismRenovascular diseasePotassium wastingLaboratory parametersLicorice ingestionClinical presentationMineralocorticoid excessClinical syndromeRare patientsPathogenetic mechanismsExcess syndromeUnusual syndromeHypertension
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