2025
Treatment outcomes of successful M1 versus M2 thrombectomy for low-ASPECTS stroke patients.
Chen H, Colasurdo M, Matsukawa H, Cunningham C, Maier I, Jabbour P, Kim J, Wolfe S, Rai A, Starke R, Psychogios M, Shaban A, Goyal N, Yoshimura S, Cuellar H, Howard B, Alawieh A, Alaraj A, Ezzeldin M, Romano D, Tanweer O, Mascitelli J, Fragata I, Polifka A, Siddiqui F, Osbun J, Crosa R, Grandhi R, Matouk C, Park M, Levitt M, Brinjikji W, Moss M, Daglioglu E, Williamson R, Navia P, Chowdhry S, Altschul D, Spiotta A, Kan P. Treatment outcomes of successful M1 versus M2 thrombectomy for low-ASPECTS stroke patients. Interventional Neuroradiology 2025, 15910199251343283. PMID: 40530425, PMCID: PMC12176791, DOI: 10.1177/15910199251343283.Peer-Reviewed Original ResearchLow Alberta Stroke Program Early CT ScoreAlberta Stroke Program Early CT ScoreEffect of endovascular thrombectomyM2 occlusionsIntracranial hemorrhageM2 patientsAssociated with intracranial hemorrhageOdds of all-cause mortalityMulticenter retrospective studyOdds of poor outcomeMultivariate logistic regression modelAll-cause mortalityMiddle cerebral arteryStroke patientsM1 patientsM1 occlusionCT scoreRetrospective studyLogistic regression modelsPoor outcomeMultivariable adjustmentPrimary outcomeCerebral arteryTreatment outcomesEndovascular thrombectomyNexfin versus conventional oscillometric cuff for blood pressure monitoring during neuro-endovascular procedures
Chen H, Njonkou-Tchoquessi R, Colasurdo M, Cobb C, Payabvash S, Malhotra A, Gandhi D. Nexfin versus conventional oscillometric cuff for blood pressure monitoring during neuro-endovascular procedures. Brain Circulation 2025 DOI: 10.4103/bc.bc_146_24.Peer-Reviewed Original ResearchNeuro-endovascular proceduresBlood pressureSystolic BPArterial lineNeurological injurySingle-center retrospective studyPredictive valueNegative predictive valuePositive predictive valueAcute neurological injuryBlood pressure monitoringArterial line measurementsConsecutive patientsRelative hypotensionRetrospective studyNeuro-endovascular treatmentNeuroendovascular interventionsNeuroendovascular proceduresSBP dropNexfinClinical scenariosNoninvasive blood pressureBP monitoringPatientsConventional cuffDiagnostic yield of an abbreviated MRI protocol in the evaluation of dizziness in the emergency department, a single institutional experience
Shareef F, Tu L, Neupane A, Siddique Z, Joshi R, Melnick E, Wira C, Mahajan A. Diagnostic yield of an abbreviated MRI protocol in the evaluation of dizziness in the emergency department, a single institutional experience. Emergency Radiology 2025, 1-10. PMID: 40471503, DOI: 10.1007/s10140-025-02349-y.Peer-Reviewed Original ResearchAbbreviated MRI protocolDiagnostic yieldIntracranial pathologyEmergency departmentAcute findingsMRI protocolEvaluation of dizzinessMethodThis retrospective studyDetecting intracranial pathologySignificant intracranial pathologyAxial DWIAxial FLAIRProtocol MRIAbbreviated protocolSupratentorial pathologySWI sequencesMRI findingsRetrospective studyUrgent care settingsAdult patientsCentral etiologyAcute dizzinessInfratentorial siteInstitutional experienceInfarct characteristicsAdvance care planning documentation prior to end-of-life systemic therapy: A single institution retrospective review.
Xiang J, Wiese B, Patlovich K, Taylor J, Adelson K, Ratan R. Advance care planning documentation prior to end-of-life systemic therapy: A single institution retrospective review. Journal Of Clinical Oncology 2025, 43 DOI: 10.1200/jco.2025.43.16_suppl.e24031.Peer-Reviewed Original ResearchSystemic anticancer therapyMonths of lifeTargeted therapyDose of treatmentAdvance care planning notesFinal treatmentAdvance care planningEnd-of-lifeHigher risk of mortalityDocumented discussionAssociated with decreased quality of lifeRisk of mortalityAssociated with decreased qualityMetastatic diseaseHigh healthcare useInpatient settingSolid tumorsRetrospective studyMD AndersonCellular therapyMedical oncologistsAnticancer therapyImmunotherapyTherapyPatientsThe treatment of cutaneous immune-related adverse events from immune checkpoint inhibitors with biologic therapy: A single-institution retrospective study at a tertiary care cancer center
Greenberg A, Valido K, Vesely M, Leventhal J. The treatment of cutaneous immune-related adverse events from immune checkpoint inhibitors with biologic therapy: A single-institution retrospective study at a tertiary care cancer center. Journal Of The American Academy Of Dermatology 2025 PMID: 40345549, DOI: 10.1016/j.jaad.2025.04.075.Peer-Reviewed Original ResearchEarly spontaneous resolution of vesicoureteral reflux from voiding cystourethrogram: a comparison of contemporary prediction models
Khondker A, Kim J, Arlen A, Rickard M, Chua M, Kirsch A, Lorenzo A, Cooper C. Early spontaneous resolution of vesicoureteral reflux from voiding cystourethrogram: a comparison of contemporary prediction models. Journal Of Pediatric Urology 2025 PMID: 40368726, DOI: 10.1016/j.jpurol.2025.04.030.Peer-Reviewed Original ResearchUreteral diameter ratioFollow-up VCUGVesicoureteral reflux gradeVesicoureteral refluxAssociated with resolutionVUR resolutionSpontaneous resolution of vesicoureteral refluxResolution of vesicoureteral refluxDegree of VURResolved vesicoureteral refluxVesicoureteral reflux resolutionPrimary vesicoureteral refluxSpontaneous complete resolutionArea under the receiver-operatingImprove risk stratificationMultivariate logistic regressionAssociated with lower oddsVUR gradeVoiding cystourethrogramRenal scarringComplete resolutionRetrospective studyUreteral anomaliesClinical outcomesRisk stratificationComplete Blood Cell Count Parameters Predict Mortality in Patients with Hypersensitivity Pneumonitis
Katsaras M, Sotiropoulou V, Manali E, Fouka E, Papakosta D, Bendstrup E, Kolilekas L, Tomos I, Tzilas V, Ntolios P, Steiropoulos P, Papanikolaou I, Gogali A, Kostikas K, Tsiri P, Papaioannou O, Malakounidou E, Theohari E, Christopoulos I, Sampsonas F, Papiris S, Rovina N, Bouros D, Tzouvelekis A. Complete Blood Cell Count Parameters Predict Mortality in Patients with Hypersensitivity Pneumonitis. Diagnostics 2025, 15: 1038. PMID: 40310410, PMCID: PMC12025666, DOI: 10.3390/diagnostics15081038.Peer-Reviewed Original ResearchEosinophil-lymphocyte ratioComplete blood count parametersBlood count parametersHypersensitivity pneumonitisEosinophil countReceiver operating characteristicPrognostic potentialMonocyte countPrognostic biomarkerCount parametersOptimal cut-off thresholdTreatment naive patientsChronic lung diseaseRisk of mortalityIncreased mortality riskWorse survivalClinical courseRetrospective studyLung diseasePredicting mortalityCut-off thresholdsPatientsMonocytesMortality riskEosinophilsManagement and Outcomes in Confirmed or Suspected Acute Symptomatic Seizure: Role of Structured Outpatient Care
Punia V, Byrnes M, Thompson N, Ayub N, Rubinos C, Zafar S, Sivaraju A, Ying Z, Fesler J, Hantus S, investigators P. Management and Outcomes in Confirmed or Suspected Acute Symptomatic Seizure: Role of Structured Outpatient Care. Annals Of Clinical And Translational Neurology 2025, 12: 1225-1239. PMID: 40244869, PMCID: PMC12172096, DOI: 10.1002/acn3.70039.Peer-Reviewed Original ResearchConceptsAcute symptomatic seizuresSymptomatic seizuresUnprovoked seizuresASyS patientsEpileptiform abnormalitiesMedian 14-month follow-upContinuous EEGRetrospective study of adultsCox proportional hazards modelsCause-specific Cox proportional hazards modelsProportional hazards modelRisk of unprovoked seizuresOutpatient EEGAlive patientsStudy of adultsOutpatient careSingle-centerRetrospective studyFollow-upPatientsCumulative incidence functionHazards modelSeizuresPost-discharge managementAbnormalitiesLater midline shift is associated with better post-hospitalization discharge status after large middle cerebral artery stroke
Song J, Stafford R, Pohlmann J, Kim I, Cheekati M, Dennison S, Brush B, Chatzidakis S, Huang Q, Smirnakis S, Gilmore E, Mohammed S, Abdalkader M, Benjamin E, Dupuis J, Greer D, Ong C. Later midline shift is associated with better post-hospitalization discharge status after large middle cerebral artery stroke. Scientific Reports 2025, 15: 11738. PMID: 40188256, PMCID: PMC11972405, DOI: 10.1038/s41598-025-95954-3.Peer-Reviewed Original ResearchConceptsMiddle cerebral arteryPeak edemaMiddle cerebral artery strokeMidline shiftCerebral edemaDecompressive hemicraniectomyRetrospective study of patientsMiddle cerebral artery territory infarctionStudy of patientsDischarge statusFavorable discharge statusAssociated with higher oddsRetrospective studyTerritory infarctionCerebral arteryEdemaTreatment decisionsPatientsIschemic strokeHigher oddsMultivariate modelArtery strokeUnfavorable dischargeTwo-centerMachine learning predicting acute pain and opioid dose in radiation treated oropharyngeal cancer patients
Salama V, Humbert-Vidan L, Godinich B, Wahid K, ElHabashy D, Naser M, He R, Mohamed A, Sahli A, Hutcheson K, Gunn G, Rosenthal D, Fuller C, Moreno A. Machine learning predicting acute pain and opioid dose in radiation treated oropharyngeal cancer patients. Frontiers In Pain Research 2025, 6: 1567632. PMID: 40256643, PMCID: PMC12006146, DOI: 10.3389/fpain.2025.1567632.Peer-Reviewed Original ResearchMorphine equivalent daily doseBaseline pain scoresPain intensityOpioid doseRadiation therapyAnalgesic efficacyPain scoresAcute painPatients treated with RTOral cavity/oropharyngeal cancerPersonalized pain managementPredicting pain intensityOropharyngeal cancer patientsAcute pain severityEquivalent daily doseEarly risk stratificationVital signsLogistic regressionRisk stratification modelOpioid requirementsPain severityDaily doseRetrospective studyRisk stratificationPain managementDeep learning-enabled, computed-tomography-based race- and sex-specific epicardial adipose tissue thresholds for cardiovascular risk stratification
Buchwald M, Shanbhag A, Miller R, Zhang W, Michalowska A, Killekar A, Lemley M, Kavanagh P, Fujito H, Liang J, Builoff V, Knight S, Einstein A, Miller E, Feher A, Sinusas A, Chareonthaitawee P, Bullock-Palmer R, Di Carli M, Berman D, Dey D, Slomka P. Deep learning-enabled, computed-tomography-based race- and sex-specific epicardial adipose tissue thresholds for cardiovascular risk stratification. Progress In Biomedical Optics And Imaging 2025, 13410: 1341011-1341011-7. DOI: 10.1117/12.3047613.Peer-Reviewed Original ResearchEpicardial adipose tissueAmount of epicardial adipose tissueComputed tomography attenuation correctionVolume of epicardial adipose tissueSex-specific thresholdsMyocardial infarctionCardiac sizeFollow-upEAT valuesEpicardial adipose tissue densityFamily history of coronary artery diseaseHistory of coronary artery diseaseHeart sizeLeft ventricle sizeBody surface areaNonfatal myocardial infarctionBody mass indexCoronary artery diseaseRisk of deathCardiovascular risk stratificationCigarette smoking statusPrognostic valueRetrospective studyRisk stratificationVentricle size1031 Variations in Academic Neurosurgery Physician Compensation in the United States
Koo A, Stogniy S, Renedo D, Sujijantarat N, Elsamadicy A, Amllay A, Kanzler M, Antonios J, Hebert R, Malhotra A, Matouk C. 1031 Variations in Academic Neurosurgery Physician Compensation in the United States. Neurosurgery 2025, 71: 139-139. DOI: 10.1227/neu.0000000000003360_1031.Peer-Reviewed Original ResearchAmerican Association of Medical CollegesUnited StatesMedian compensationSalary survey dataFull-time academic facultyAnnual compensationCompensation dataSalary compensationEquitable payPhysician compensationNeurosurgery facultyNeurosurgical specialtyNeurosurgical workforceFaculty membersSalary inequitiesRetrospective studySurvey dataCompensationNeurosurgery departmentPayMedical CollegeAmerican AssociationAcademic facultyProfessorStudy period573 Feasibility of an Unfunded Multicenter Trial Group for Older Adult Burn Patients: A Retrospective Study
Nosanov L, Savetamal A, Reynolds J, Bhavsar D, Miotke S, Johnston M, Wibbenmeyer L, Galet C, Hill D, Higginson S, Chin T, Long A, Baker E, Hamm H, Lacey A, Paine R, Tedesco D, Tejiram S, Jeschke M, Romanowski K. 573 Feasibility of an Unfunded Multicenter Trial Group for Older Adult Burn Patients: A Retrospective Study. Journal Of Burn Care & Research 2025, 46: s158-s159. PMCID: PMC11958010, DOI: 10.1093/jbcr/iraf019.202.Peer-Reviewed Original ResearchAdult burn patientsOlder burn patientsLength of hospital stayRetrospective pilot studyBurn patientsTrial groupRetrospective studyHospital stayMedian length of hospital staySingle-center studyTotal body surface areaBurn patient populationMedian time to wound healingTime to wound healingBody surface areaIn-hospital mortalityMedian burn sizePilot studyMedian BMIIQR 6Median ageClinical outcomesOlder adultsICU stayIQR 5Real-World Evidence of Administration of Biologic Agents in Patients with Severe Asthma: An Analysis of the Respiratory Department of University Hospital of Patras Asthma Registry
Papaioannou O, Christopoulos I, Tsiri P, Sampsonas F, Karkoulias K, Lykouras D, Sotiropoulou V, Theohari E, Papalexatos D, Komninos D, Christopoulos A, Tzouvelekis A. Real-World Evidence of Administration of Biologic Agents in Patients with Severe Asthma: An Analysis of the Respiratory Department of University Hospital of Patras Asthma Registry. Journal Of Clinical Medicine 2025, 14: 2174. PMID: 40217624, PMCID: PMC11989620, DOI: 10.3390/jcm14072174.Peer-Reviewed Original ResearchTime of diagnosisOral corticosteroidsSevere asthmaFollow-upBiological agentsBlood eosinophilsAdministration of biological agentsInitiation of biologic treatmentMedian valueTreated with biologic agentsTreated with omalizumabUncontrolled severe asthmaUse of corticosteroidsSevere asthma exacerbationsAsthma outpatient clinicLongitudinal useConsecutive patientsMedian ageDisease phenotypic characteristicsRetrospective studyNever smokersCorticosteroidsAsthma exacerbationsAsthma flaresLung functionThe Use of Intravascular Ultrasound During Deep Venous Interventions in a Tertiary Care Center
Ali S, Rodriguez P, Abualanain E, Li Y, Khalil M, Aboloyoun H, Lozada J, Aboian E, Attaran R, Chaar C. The Use of Intravascular Ultrasound During Deep Venous Interventions in a Tertiary Care Center. Vascular And Endovascular Surgery 2025, 59: 505-512. PMID: 40096827, DOI: 10.1177/15385744251326989.Peer-Reviewed Original ResearchConceptsDeep venous interventionsPrimary patency rateVenous interventionsLoss of patencyPatency ratesAssociated with loss of patencyAssociated with fewer complicationsIVUS useMethodsThis retrospective studyTertiary care centerLower extremity interventionsChronic kidney diseaseMultiplanar venographyAssociated with lossConsecutive patientsRates of COPDPrimary patencyVenous stentingTechnical successFewer complicationsSymptomatic improvementVenous stenosisAnticoagulant useRetrospective studyHypercoagulable stateSpatial-temporal patterns and typology of attacks against healthcare in the Occupied Palestinian Territory.
Aly S, Surapaneni T, Subeh M, Wang Q, Andersen D, Mowafi H, Poole D. Spatial-temporal patterns and typology of attacks against healthcare in the Occupied Palestinian Territory. Eastern Mediterranean Health Journal 2025, 31: 59-67. PMID: 40116255, DOI: 10.26719/2025.31.2.59.Peer-Reviewed Original ResearchConceptsHealth facilitiesInternational humanitarian lawOccupied Palestinian TerritoriesNearest health facilityHumanitarian lawStudy periodWest BankPalestinian territoriesChi-square analysisHealthcareHealthcare infrastructureAl-ShifaArmed conflictWeapon dataZ-testReports of attacksLawGazaWeaponsType of attackGeospatial analysisTerritoryFacilitiesRetrospective studyInterventionSafety and efficacy of immune checkpoint therapy for the treatment of patients with cardiac metastasis: a multicenter international retrospective study
Nassar A, Alaiwi S, Zarif T, Denu R, Macaron W, Abdel-Wahab N, Freeman D, Vasbinder A, Hayeck S, Anderson E, Goodman R, Johnson D, Grynberg S, Shapira R, Kwan J, Woodford R, Long G, Haykal T, Dent S, Kojima Y, Yonemor K, Tandon A, Trevino A, Akhter N, Yang E, Hui G, Drakaki A, El-Am E, Kozaily E, Al-Hader A, Farhat E, Babu P, Mittra A, Li M, Jones N, Baena J, Herrera M, Foderaro S, Nana F, Kim C, Sackstein P, Parikh K, Desai A, Smith C, Cortellini A, Pinato D, Korolewicz J, Lopetegui-Lia N, Funchain P, Choudhary A, Asnani A, Navani V, Meyers D, Stukalin I, Gallegos J, Trent J, Nusrat S, Malvar C, McKay R, Neilan T, Choueiri T, Naqash A. Safety and efficacy of immune checkpoint therapy for the treatment of patients with cardiac metastasis: a multicenter international retrospective study. Journal For ImmunoTherapy Of Cancer 2025, 13: e009364. PMID: 40032601, PMCID: PMC11877189, DOI: 10.1136/jitc-2024-009364.Peer-Reviewed Original ResearchConceptsImmune checkpoint inhibitor initiationImmune checkpoint inhibitorsTreatment-related adverse eventsObjective response rateProgression-free survivalCardiac metastasisOverall survivalRetrospective studyAnti-cytotoxic T-lymphocyte antigen 4Dose of immune checkpoint inhibitorsEfficacy of immune checkpoint therapyAnti-programmed death-1International multicenter retrospective studyMulticenter international retrospective studyT-lymphocyte antigen-4Non-small cell lung cancerMedian follow-up timeClinical outcomes of patientsICI-based regimensMultiple cardiac metastasesSolid Tumors V.1.1Immune checkpoint therapyResponse Evaluation CriteriaInternational retrospective studyMulticenter retrospective studyReal-World Analysis of Strategies to Prevent Thrombosis and Bleeding in Adults with ALL Treated with Asparaginase
Mort J, Brighton D, Mautner B, Pierce E, Ghamsari F, Allen C, D’souza D, Patel I, Lawson J, Jackson C, Abernathy K, Yelvington B, Miller R, Dholaria B, Wolfe H, Infield J, Locke S, Shallis R, Duong V, Reed D, Walsh K, LeBlanc T, Keng M, Horton B, Chaer F. Real-World Analysis of Strategies to Prevent Thrombosis and Bleeding in Adults with ALL Treated with Asparaginase. Blood Vessels Thrombosis & Hemostasis 2025, 100065. DOI: 10.1016/j.bvth.2025.100065.Peer-Reviewed Original ResearchAcute lymphoblastic leukemiaOdds of thrombosisProphylactic anticoagulationPEG-ASPIncreased rate of thrombosisPrognosis of adult patientsAcute lymphoblastic leukemia therapyPediatric-inspired regimensPeripherally inserted central cathetersRandomized prospective studyRate of thrombosisOdds of bleedingAssociated thrombosisPegylated asparaginaseLymphoblastic leukemiaThrombotic riskRetrospective studyThrombotic eventsAdult patientsReal-world analysisProspective studyCentral cathetersBleedingMultivariate analysisAnticoagulationInpatient Immunotherapy Outcomes Study: A Multicenter Retrospective Analysis.
Riaz F, Vaughn J, Zhu H, Dickerson J, Sayegh H, Brongiel S, Baldwin E, Kier M, Zaemes J, Hearn C, Abdelghany O, Cohen R, Parikh R, Reuss J, Prsic E, Doroshow D. Inpatient Immunotherapy Outcomes Study: A Multicenter Retrospective Analysis. JCO Oncology Practice 2025, op2400788. PMID: 39937997, DOI: 10.1200/op-24-00788.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsOverall survivalICI administrationSolid malignanciesPatients treated with immune checkpoint inhibitorsAdministration of immune checkpoint inhibitorsMultivariate Cox proportional hazards model analysisResponse to ICI therapyCox proportional hazards model analysisProportional hazards model analysisAdvanced solid malignanciesKaplan-Meier methodOutcomes of patientsInstitutional electronic medical recordsHazards model analysisCox proportional hazards modelsProportional hazards modelCheckpoint inhibitorsICI therapyMedian OSICI initiationICI useRetrospective studyClinical outcomesClinicodemographic variablesPredictors of Delayed Surgery After Distal Radius Fracture: A Large National Database Study.
Ratnasamy P, Allam O, Kammien A, Joo P, Luo X, Grauer J. Predictors of Delayed Surgery After Distal Radius Fracture: A Large National Database Study. Orthopedics 2025, 48: e75-e80. PMID: 39933104, DOI: 10.3928/01477447-20250204-01.Peer-Reviewed Original ResearchConceptsDistal radius fracturesDelayed surgeryRadius fracturesImmediate surgeryClinical factorsDistal radius fracture surgeryTime of surgeryCohort of patientsDemographics of patientsNon-clinical factorsFracture surgeryIndependent predictorsRetrospective studySurgical timeImpact patient outcomesMultivariate analysisSurgerySmoking statusComorbidity burdenPatientsWeek 0 to 2Patient outcomesWeek 3WeeksNon-clinical
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply