2024
Novel Mechanical Aspiration Thrombectomy in Patients With Acute Pulmonary Embolism: Results From the Prospective APEX-AV Trial
Ranade M, Foster M, Brady P, Sokol S, Butty S, Klein A, Maholic R, Safar A, Patel T, Zlotnick D, Gans D, Pollak J, Ferrera D, Stegman B, Basra S, Moriarty J, Keeling B, Investigators A. Novel Mechanical Aspiration Thrombectomy in Patients With Acute Pulmonary Embolism: Results From the Prospective APEX-AV Trial. Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 4: 102463. PMID: 40061412, PMCID: PMC11887559, DOI: 10.1016/j.jscai.2024.102463.Peer-Reviewed Original ResearchAcute intermediate-risk PEMechanical aspiration thrombectomyIntermediate-risk PEPulmonary embolismAspiration thrombectomyRV/LV ratioClot burdenAdverse eventsMm HgLow rate of adverse eventsMean pulmonary artery pressureEnd pointsRate of adverse eventsAcute pulmonary embolismPulmonary artery pressureSafety end pointDevice-related deathsTreat pulmonary embolismSingle-arm studyEffectiveness end pointAccess site bleedingStatistically significant reductionCardiac injuryClinical deteriorationArterial pressureMechanical clot disruption during pulmonary thromboembolectomy is safe: A propensity score-matched analysis
Thomas S, Deshmukh A, Mojibian H, Marino A, Lozada J, Cornman-Homonoff J. Mechanical clot disruption during pulmonary thromboembolectomy is safe: A propensity score-matched analysis. Clinical Imaging 2024, 118: 110381. PMID: 39637758, DOI: 10.1016/j.clinimag.2024.110381.Peer-Reviewed Original ResearchPulmonary thromboembolectomyPulmonary emboliPulmonary arteryRight pulmonary arteryLeft pulmonary arteryPulmonary artery pressureAdministration of anticoagulantsDuration of hospitalizationMechanical clot disruptionPropensity-score matchingSPESI scorePulmonary vasculatureArterial pressureClinical effectsOrganized thrombusThromboembolectomyPropensity-scoreClot disruptionInclusion criteriaPatientsMortality rateRisk categoriesCompare groupsStudy periodArteryPeak Tricuspid Regurgitation Jet Velocity and Kidney Outcomes in Patients With Heart Failure With Preserved Ejection Fraction
Oka T, Tighiouart H, McCallum W, Tuttle M, Testani J, Sarnak M. Peak Tricuspid Regurgitation Jet Velocity and Kidney Outcomes in Patients With Heart Failure With Preserved Ejection Fraction. Kidney International Reports 2024, 9: 3035-3044. PMID: 39430198, PMCID: PMC11489825, DOI: 10.1016/j.ekir.2024.07.009.Peer-Reviewed Original ResearchLeft ventricular ejection fractionPulmonary artery pressureCreatinine doublingEGFR declineEjection fractionKidney outcomesHeart failurePeak tricuspid regurgitant jet velocityDoubling of serum creatinineTricuspid regurgitant jet velocityElevated pulmonary artery pressureAssociated with lower eGFRWorsening kidney functionVentricular ejection fractionRegurgitant jet velocityCox proportional hazards modelsProportional hazards modelPost hoc analysisBaseline eGFRSerum creatinineLow eGFRTOPCAT trialFollow-upKidney functionArterial pressureThe Predictive Value of Qanadli and Miller Index Scores in Patients with Intermediate-High–Risk and High-Risk Pulmonary Emboli Undergoing Aspiration Thrombectomy
Fish A, Knight E, Mutonga M, Moulton J, Gathagan R, Andreca M, Sare A, Cornman-Homonoff J. The Predictive Value of Qanadli and Miller Index Scores in Patients with Intermediate-High–Risk and High-Risk Pulmonary Emboli Undergoing Aspiration Thrombectomy. Journal Of Vascular And Interventional Radiology 2024, 35: 1457-1463. PMID: 38969337, DOI: 10.1016/j.jvir.2024.06.031.Peer-Reviewed Original ResearchPulmonary artery pressureIntensive care unitMiller scoreHigh-risk patientsArterial pressureInstitutional review boardPulmonary pressureClot burdenB-type natriuretic peptideIntensive care unit length of stayAssociated with ICU lengthIntensive care unit lengthLength of stayFlowTriever SystemConsecutive patientsEchocardiographic findingsPulmonary emboliCreatinine levelsPulmonary embolismNatriuretic peptideStratify patientsRetrospective studyClinical outcomesAspiration thrombectomyICU lengthEffect of Filtered Blood Return on Outcomes of Pulmonary Aspiration Thrombectomy
Bitar R, Bozal S, Sisti A, Mojibian H, Marino A, Cornman-Homonoff J. Effect of Filtered Blood Return on Outcomes of Pulmonary Aspiration Thrombectomy. Journal Of Vascular And Interventional Radiology 2024, 35: 1447-1456. PMID: 38950819, DOI: 10.1016/j.jvir.2024.06.026.Peer-Reviewed Original ResearchPulmonary artery pressureAspiration thrombectomyPulmonary embolismArterial pressureDuration of intensive care unitSeverity of adverse eventsLength of hospital stayHigh-risk PEProcedure-related complicationsAdverse event ratesIntensive care unitMarker of procedural successFluoroscopy timeTransfusion requirementsBlood lossNo significant differenceTransfusion needsHospital stayPost-procedureProcedural successAdverse eventsSurrogate markerLaboratory valuesProcedural outcomesProcedural detailsRight Ventricular Pressure Waveform Analysis—Clinical Relevance and Future Directions
Heerdt P, Kheyfets V, Oakland H, Joseph P, Singh I. Right Ventricular Pressure Waveform Analysis—Clinical Relevance and Future Directions. Journal Of Cardiothoracic And Vascular Anesthesia 2024, 38: 2433-2445. PMID: 39025682, PMCID: PMC11580041, DOI: 10.1053/j.jvca.2024.06.022.Peer-Reviewed Original ResearchRight ventricular pressureRight ventricular functionVentricular pressureVentricular functionMeasuring right ventricular pressureMeasurements of right ventricular pressurePeak right ventricular pressurePulmonary artery pressureEvaluate cardiac functionPulmonary arteryStroke volume measurementsRight atriumCardiac functionDiastolic fillingSurgical patientsArterial pressureClinical valueDemonstrating utilityVolume measurementsMeasurements of pressurePressure waveformAccurate surrogateContinuous measurement of pressurePhysiological factorsEchocardiographyRecurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension
Fish A, Wang D, Knight E, Pollak J, Schlachter T. Recurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension. Journal Of Vascular And Interventional Radiology 2024, 35: 1148-1153. PMID: 38692392, DOI: 10.1016/j.jvir.2024.04.017.Peer-Reviewed Original ResearchPulmonary arteriovenous malformationsPulmonary hypertensionArteriovenous malformationsRecurrence of pulmonary arteriovenous malformationsFollow-upChest CT follow-upPresence of pulmonary hypertensionCT follow-upShorter surveillance intervalsPulmonary artery pressureHistory of smokingPresence of PHCuracao criteriaSurveillance intervalsSmoking historyArterial pressureMultivariate analysisRecurrenceGenetic testingOdds ratioHypertensionPatientsStratified analysisGeneral demographicsStudy periodPulmonary Hypertension and the Risk of 30-Day Postoperative Pulmonary Complications after Gastrointestinal Surgical or Endoscopic Procedures: A Retrospective Propensity Score-Weighted Cohort Analysis
Tatsuoka Y, Carr Z, Jayakumar S, Lin H, He Z, Farroukh A, Heerdt P. Pulmonary Hypertension and the Risk of 30-Day Postoperative Pulmonary Complications after Gastrointestinal Surgical or Endoscopic Procedures: A Retrospective Propensity Score-Weighted Cohort Analysis. Journal Of Clinical Medicine 2024, 13: 1996. PMID: 38610760, PMCID: PMC11012853, DOI: 10.3390/jcm13071996.Peer-Reviewed Original ResearchPostoperative pulmonary complicationsLength of stayPulmonary hypertensionPulmonary complicationsPulmonary embolismRespiratory failureEndoscopic proceduresRisk of postoperative complicationsPulmonary artery pressurePreoperative risk assessmentProlonged length of stayRetrospective cohort studySub-cohort analysisIncreased LOSPropensity score overlap weightingOverlap weightingAssociation of PHPH cohortPH patientsPostoperative complicationsAbdominal surgeryRate of RFCohort studyControl cohortArterial pressure
2023
The Current Landscape of Transcatheter Tricuspid Valve Intervention
Seligman H, Vora A, Haroian N, Puri R, Heng E, Smith R, Latib A, Makkar R, Sorajja P, Leon M, Ahmad Y. The Current Landscape of Transcatheter Tricuspid Valve Intervention. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 2: 101201. PMID: 39131057, PMCID: PMC11307702, DOI: 10.1016/j.jscai.2023.101201.Peer-Reviewed Original ResearchTricuspid regurgitationHeart failureTranscatheter tricuspid valve interventionCaval valve implantationRight heart failureWorse tricuspid regurgitationPulmonary artery pressureReduced ejection fractionSevere tricuspid regurgitationAge-adjusted prevalenceMainstay of therapyTricuspid valve interventionMore contemporary dataArtery pressureValve implantationEjection fractionValve interventionAdverse prognosisValve repairTranscatheter interventionsTR severityPrevalence increasesPotential rolePatientsContemporary dataPulmonary artery wave intensity analysis in a pig model of lung resection
KEAST T, GLASS A, MCCALL P, SHELLEY B, HEERDT P. Pulmonary artery wave intensity analysis in a pig model of lung resection. Journal Of Cardiothoracic And Vascular Anesthesia 2023, 37: 9-10. DOI: 10.1053/j.jvca.2023.08.023.Peer-Reviewed Original ResearchForward compression waveBackward compression waveWave intensity analysisControl subjectsLung resectionPulmonary arteryPig modelSystolic timeCardiovascular MRIInvasive haemodynamic dataPulmonary artery pressureRight ventricular functionProximal pulmonary arteriesMain pulmonary arteryPost-operative patientsRight ventricular contractionWave reflection indicesMann-Whitney testIncreased afterloadLabChart softwareArtery pressureHaemodynamic effectsRV functionUpper lobectomyVentricular functionWireless pulmonary artery sensor implantation in a unilateral lung transplant recipient
Kelly R, Bae J, Mansour A, Nagpal S, Hahn S, Murugiah K. Wireless pulmonary artery sensor implantation in a unilateral lung transplant recipient. Journal Of Cardiology Cases 2023, 28: 216-220. PMID: 38024115, PMCID: PMC10658300, DOI: 10.1016/j.jccase.2023.08.004.Peer-Reviewed Case Reports and Technical NotesPulmonary artery pressure monitorLung transplant recipientsLung transplantationCardioMEMS deviceTransplant recipientsHeart failurePressure monitorPulmonary artery injuryPulmonary artery pressureDevice-related complicationsSelective pulmonary angiographyFirst such caseArtery pressureVentricular failureArtery injuryHemodynamic managementPost transplantationHemodynamic assessmentPulmonary angiographyRight PAInvasive monitoringTransplantationSignificant tortuositySmall caliberTwo yearsCognitive impairment in pulmonary arterial hypertension
Heller S, See C, Singh I, Fredericks C. Cognitive impairment in pulmonary arterial hypertension. Annals Of Clinical And Translational Neurology 2023, 10: 1899-1903. PMID: 37550957, PMCID: PMC10578884, DOI: 10.1002/acn3.51867.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionCognitive impairmentArterial hypertensionPulmonary artery pressureRight heart dysfunctionPulmonary vascular remodelingCognitive impairment syndromeVascular cognitive impairmentArtery pressureCardiopulmonary exerciseHeart dysfunctionNoninvasive markerCognitive dysfunctionVascular remodelingAdult subjectsImpairmentHypertensionUnderlying mechanismAbnormal increaseDysfunctionSyndromeCognitive evaluationSubjectsAcute outcomes for the full US cohort of the FLASH mechanical thrombectomy registry in pulmonary embolism.
Toma C, Jaber W, Weinberg M, Bunte M, Khandhar S, Stegman B, Gondi S, Chambers J, Amin R, Leung D, Kado H, Brown M, Sarosi M, Bhat A, Castle J, Savin M, Siskin G, Rosenberg M, Fanola C, Horowitz J, Pollak J. Acute outcomes for the full US cohort of the FLASH mechanical thrombectomy registry in pulmonary embolism. EuroIntervention 2023, 18: 1201-1212. PMID: 36349702, PMCID: PMC9936254, DOI: 10.4244/eij-d-22-00732.Peer-Reviewed Original ResearchConceptsHigh-risk PEDevice-related deathsPulmonary artery pressureMajor adverse eventsAdverse eventsMechanical thrombectomyFlowTriever SystemArtery pressureUS cohortLarge real-world populationMean pulmonary artery pressureImmediate haemodynamic improvementIntraprocedural adverse eventsPrimary safety endpointRight ventricle/Favorable safety profileIntensive care unitPulmonary embolism treatmentReal-world populationDyspnoea improvementHaemodynamic improvementMajor bleedingRisk PECardiac indexCause mortality
2022
Recommendations for the Use of Echocardiography in the Evaluation of Rheumatic Heart Disease: A Report from the American Society of Echocardiography
Pandian N, Kim J, Arias-Godinez J, Marx G, Michelena H, Chander Mohan J, Ogunyankin K, Ronderos R, Sade L, Sadeghpour A, Sengupta S, Siegel R, Shu X, Soesanto A, Sugeng L, Venkateshvaran A, Campos Vieira M, Little S. Recommendations for the Use of Echocardiography in the Evaluation of Rheumatic Heart Disease: A Report from the American Society of Echocardiography. Journal Of The American Society Of Echocardiography 2022, 36: 3-28. PMID: 36428195, DOI: 10.1016/j.echo.2022.10.009.Peer-Reviewed Original ResearchConceptsRheumatic heart diseaseDiagnosis of rheumatic heart diseaseSeverity of valvular lesionsHeart diseaseRestricted leaflet mobilityAmerican Society of EchocardiographyEchocardiographic diagnosis of rheumatic heart diseasePost-intervention complicationsModalities of echocardiographyUsefulness of echocardiographyPulmonary artery pressureMixed valve diseaseAcute rheumatic feverPresence of subclinical diseasePre-treatment planningTreatment of rheumatic heart diseaseEchocardiographic surveillanceSubvalvular abnormalitiesEchocardiographic diagnosisMitral stenosisSurgical treatmentEchocardiographic guidanceLeaflet mobilityLeaflet thickeningValvular lesionsChanges in inferior vena cava area represent a more sensitive metric than changes in filling pressures during experimental manipulation of intravascular volume and tone
Ivey‐Miranda J, Wetterling F, Gaul R, Sheridan S, Asher JL, Rao VS, Maulion C, Mahoney D, Mebazaa A, Gray AP, Burkhoff D, Cowie MR, Cox ZL, Butler J, Fudim M, McDonald K, Damman K, Borlaug BA, Testani JM. Changes in inferior vena cava area represent a more sensitive metric than changes in filling pressures during experimental manipulation of intravascular volume and tone. European Journal Of Heart Failure 2022, 24: 455-462. PMID: 34837447, PMCID: PMC9306514, DOI: 10.1002/ejhf.2395.Peer-Reviewed Original ResearchConceptsInferior vena cavaCardiac filling pressuresPulmonary artery pressureIntravascular volumeFilling pressureArtery pressureVolume statusVascular toneCardiac functionCross-sectional areaLeft-sided cardiac filling pressuresIVC cross-sectional areaHeart failure hospitalizationRight heart catheterizationChronic HFFailure hospitalizationHeart catheterizationCardiac dysfunctionVenous conduitsColloid infusionVena cavaVenous systemRapid pacingIVC areaVolume loading9 Systemic and pulmonary arterial hypertension
Selzer A, Fontes M, Heerdt P. 9 Systemic and pulmonary arterial hypertension. 2022, 187-202. DOI: 10.1016/b978-0-323-71860-8.00018-5.Peer-Reviewed Original ResearchPulmonary artery pressurePulmonary hypertensionSystemic hypertensionArterial pressurePrevalence of pulmonary arterial hypertensionDiagnosis of pulmonary hypertensionSixth World SymposiumRight heart catheterizationPulmonary arterial hypertensionAmerican College of Cardiology/American Heart AssociationPharmacological treatment modalitiesPrimary systemic hypertensionSystolic blood pressureHeart catheterizationPerioperative morbidityThoracic surgeryArterial hypertensionSecondary hypertensionAdult patientsTreatment modalitiesWorld SymposiumMm HgPerioperative implicationsHeart AssociationPostoperative phase
2021
Depressed right ventricular systolic function in heart failure due to constrictive pericarditis
Raizada V, Sato K, Alashi A, Kumar A, Kwon D, Ramchand J, Dillenbeck A, Zumwalt RE, Vangala AS, Earley TD, Klein A. Depressed right ventricular systolic function in heart failure due to constrictive pericarditis. ESC Heart Failure 2021, 8: 3119-3129. PMID: 34137193, PMCID: PMC8318427, DOI: 10.1002/ehf2.13418.Peer-Reviewed Original ResearchConceptsClinical heart failureConstrictive pericarditisHeart failureRight ventricularMyocardial infiltrationDiastolic fillingSystolic functionPericardial diseaseRight ventricular systolic functionBiventricular systolic functionPulmonary artery pressureVentricular systolic functionStudy of patientsProgression of fibrosisBiventricular myocardiumArtery pressureCardiac histopathologyCardiac catheterizationRV myocardiumAutopsied heartsHistopathologic examinationPericardial thicknessEcho indicesVentricular myocardiumHealthy adultsPulmonary Hypertension in Obstructive Sleep Apnea
Mohsenin V. Pulmonary Hypertension in Obstructive Sleep Apnea. 2021, 69-76. DOI: 10.1007/978-3-030-57942-5_6.Peer-Reviewed Original ResearchMean pulmonary artery pressurePulmonary hypertensionChronic obstructive pulmonary diseaseMild pulmonary arterial hypertensionPulmonary artery pressurePulmonary arterial hypertensionThird of patientsChronic lung diseaseObstructive pulmonary diseaseObstructive sleep apneaTreatment of OSADaytime hypoxemiaArterial hypertensionArtery pressureObesity hypoventilationHeart failurePulmonary diseaseSleep apneaLung diseaseHypertensionOSAPatientsDiseaseCurrent definitionHypoxemiaImaging of Pulmonary Hypertension in Adults: A Position Paper from the Fleischner Society
Remy-Jardin M, Ryerson C, Schiebler M, Leung A, Wild J, Hoeper M, Alderson P, Goodman L, Mayo J, Haramati L, Ohno Y, Thistlethwaite P, van Beek E, Knight S, Lynch D, Rubin G, Humbert M. Imaging of Pulmonary Hypertension in Adults: A Position Paper from the Fleischner Society. Radiology 2021, 298: 203108. PMID: 33399507, DOI: 10.1148/radiol.2020203108.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPulmonary hypertensionSystematic reviewCause of PHComplications of PHEvaluation of PHManagement of PHMean pulmonary artery pressureChronic thromboembolic pulmonary hypertensionTreatment of PHPulmonary artery pressureThromboembolic pulmonary hypertensionManagement of patientsSimilar pathophysiologic mechanismsUtility of CTSimultaneous joint publicationArtery pressurePathophysiologic mechanismsTherapeutic managementMultidisciplinary assessmentHemodynamic characteristicsFleischner SocietyWorking GroupTreatment planningKey roleNuclear medicineImaging of pulmonary hypertension in adults: a position paper from the Fleischner Society
Remy-Jardin M, Ryerson C, Schiebler M, Leung A, Wild J, Hoeper M, Alderson P, Goodman L, Mayo J, Haramati L, Ohno Y, Thistlethwaite P, van Beek E, Knight S, Lynch D, Rubin G, Humbert M. Imaging of pulmonary hypertension in adults: a position paper from the Fleischner Society. European Respiratory Journal 2021, 57: 2004455. PMID: 33402372, DOI: 10.1183/13993003.04455-2020.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPulmonary hypertensionSystematic reviewCause of PHComplications of PHEvaluation of PHManagement of PHMean pulmonary artery pressureChronic thromboembolic pulmonary hypertensionTreatment of PHFleischner SocietyPulmonary artery pressureThromboembolic pulmonary hypertensionManagement of patientsSimilar pathophysiologic mechanismsUtility of CTArtery pressurePathophysiologic mechanismsTherapeutic managementHaemodynamic characteristicsMultidisciplinary assessmentWorking GroupTreatment planningHypertensionKey rolePosition paper
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