2025
Chronotherapeutic intervention targeting emotion regulation brain circuitry, symptoms, and suicide risk in adolescents and young adults with bipolar disorder: a pilot randomised trial
Kim J, Sankar A, Marks R, Carrubba E, Lecza B, Quatrano S, Spencer L, Constable R, Pittman B, Lebowitz E, Silverman W, Swartz H, Blumberg H. Chronotherapeutic intervention targeting emotion regulation brain circuitry, symptoms, and suicide risk in adolescents and young adults with bipolar disorder: a pilot randomised trial. BMJ Mental Health 2025, 28: e301338. PMID: 39971594, PMCID: PMC11840897, DOI: 10.1136/bmjment-2024-301338.Peer-Reviewed Original ResearchConceptsBipolar disorderEmotion regulationSuicide riskBrain circuitryChronotherapeutic interventionsEmotional face stimuliLeft amygdala responseRisk of bipolar disorderTargeting emotion regulationReduce suicide riskHigher suicide riskYoung adultsFunctional MRI dataPost-treatment improvementAmygdala responsePotential intervention targetsEmotion dysregulationMania symptomsMood episodesFace stimuliCircuitry dysfunctionRegulation therapyDaily rhythmsWeekly sessionsSelf-monitoring
2024
Health-related quality of life among extrapulmonary tuberculosis patients and inequalities by disease manifestations: a longitudinal study analysing the impact of TB treatment
Hassan S, Purohit M, Kanthali M, Yaesoubi R, Jain S, Mustafa T. Health-related quality of life among extrapulmonary tuberculosis patients and inequalities by disease manifestations: a longitudinal study analysing the impact of TB treatment. Quality Of Life Research 2024, 34: 683-700. PMID: 39636513, PMCID: PMC11920340, DOI: 10.1007/s11136-024-03860-4.Peer-Reviewed Original ResearchPatient-reported outcome measuresQuality of lifeHealth profileHealth utilityAnalysis of patient-reported outcome measuresHealth system-level interventionsMeasure patient-reported outcome measuresAssociated with health utilityHealth-related quality of lifeSystem-level interventionsHealth-related qualityImpact of illnessHolistic patientPost-treatment improvementVisual analogue scaleHealth facilitiesImpact of TB treatmentSocioeconomic statusEQ-VASEPTB patientsOutcome measuresHealth problemsSummary measuresHealthWorking capacity
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