2024
Comparing the Accuracy and Reliability of ABC/2 and Planimetry for Vestibular Schwannoma Volume Assessment
Singh K, Abdou H, Panth N, Chiang V, Buono F, Schwartz N, Mahajan A. Comparing the Accuracy and Reliability of ABC/2 and Planimetry for Vestibular Schwannoma Volume Assessment. Otology & Neurotology 2024, 46: 196-200. PMID: 39792983, DOI: 10.1097/mao.0000000000004392.Peer-Reviewed Original ResearchConceptsTumor volume assessmentABC/2 methodVestibular schwannomaVolume assessmentPlanimetry methodTumor volumeTumor volume changesFollow-up scansOverestimate tumor volumePatients' quality of lifeTumor sizeRetrospective reviewIntracranial tumorsImprove clinical decision makingSubgroup analysisVolumetric assessmentTumorClinical decision makingQuality of lifePatients' qualityPatientsClinical settingPlanimetryImaging techniquesPositive correlationA novel preoperative score to predict severe acute cholecystitis
Kuhlenschmidt K, Taveras L, Schuster K, Kaafarani H, El Hechi M, Puri R, Crandall M, Schroeppel T, Cripps M. A novel preoperative score to predict severe acute cholecystitis. Journal Of Trauma And Acute Care Surgery 2024, 96: 870-875. PMID: 38523119, DOI: 10.1097/ta.0000000000004308.Peer-Reviewed Original ResearchAcute cholecystitisPreoperative scoresLogistic regression modelsGrading scaleAmerican Association for the SurgerySevere acute cholecystitisStepwise logistic regression modelSurgical decision makingPrognostic Level IIIMulticenter databaseMulticenter trialMulticenter validationCholecystitisCounseling patientsHigh-gradeLevel IIIC-statisticPatientsRegression modelsCholecystectomyMulticenterScoresSacPositive correlationGradeNeuropsychological insights into exercise addiction: the role of brain structure and self-efficacy in middle-older individuals
Zhang F, Shao Y, Zhang X, Zhang H, Tan Y, Yang G, Wang X, Jia Z, Gong Q, Zhang H. Neuropsychological insights into exercise addiction: the role of brain structure and self-efficacy in middle-older individuals. Cerebral Cortex 2024, 34: bhad514. PMID: 38186007, DOI: 10.1093/cercor/bhad514.Peer-Reviewed Original ResearchGray matter volumeRight inferior temporal regionMatter volumeInferior temporal regionsBrain structuresExercise addictionTemporal regionsStructural magnetic resonance imagingMagnetic resonance imagingLeft rolandic operculumSPM12 softwareDevelopment of interventionsRight hippocampusStudy populationRolandic operculumResonance imagingBehavioral assessmentPhysiological changesAddictionNeuropsychological mechanismsPsychological factorsPositive correlationNegative correlationMediation analysisIndividuals
2023
Type 2 diabetes stigma and its association with clinical, psychological, and behavioral outcomes: A systematic review and meta-analysis
Akyirem S, Ekpor E, Namumbejja Abwoye D, Batten J, Nelson L. Type 2 diabetes stigma and its association with clinical, psychological, and behavioral outcomes: A systematic review and meta-analysis. Diabetes Research And Clinical Practice 2023, 202: 110774. PMID: 37307898, DOI: 10.1016/j.diabres.2023.110774.Peer-Reviewed Original ResearchConceptsClinical outcomesPeer-reviewed observational studiesDiabetes stigmaJBI Critical Appraisal ChecklistRisk of biasStigma reduction interventionsCritical Appraisal ChecklistNegative health outcomesWeb of ScienceCochrane CENTRALInclusion criteriaObservational studyPositive correlationDepressive symptomsQuantitative research evidenceHealth outcomesModerate positive correlationSystematic reviewAppraisal ChecklistWeak positive correlationAPA PsycInfoOutcomesFurther studiesAssociationResearch evidenceImage analysis-based tumor infiltrating lymphocytes measurement predicts breast cancer pathologic complete response in SWOG S0800 neoadjuvant chemotherapy trial
Fanucci K, Bai Y, Pelekanou V, Nahleh Z, Shafi S, Burela S, Barlow W, Sharma P, Thompson A, Godwin A, Rimm D, Hortobagyi G, Liu Y, Wang L, Wei W, Pusztai L, Blenman K. Image analysis-based tumor infiltrating lymphocytes measurement predicts breast cancer pathologic complete response in SWOG S0800 neoadjuvant chemotherapy trial. Npj Breast Cancer 2023, 9: 38. PMID: 37179362, PMCID: PMC10182981, DOI: 10.1038/s41523-023-00535-0.Peer-Reviewed Original ResearchPathologic complete responseBreast cancerComplete responseTIL scoreBreast Cancer Pathologic Complete ResponseTumor-infiltrating lymphocyte scoresEvent-free survivalNeoadjuvant chemotherapy trialsLymphocyte measurementsLymphocyte scoreNeoadjuvant chemotherapyChemotherapy trialsMean pretreatmentResidual diseaseTIL quantificationPredictive valuePretreatment samplesResponse discriminationScoresStrong positive correlationPositive correlationReductions in synaptic marker SV2A in early-course Schizophrenia
Yoon J, Zhang Z, Mormino E, Davidzon G, Minzenberg M, Ballon J, Kalinowski A, Hardy K, Naganawa M, Carson R, Khalighi M, Park J, Levinson D, Chin F. Reductions in synaptic marker SV2A in early-course Schizophrenia. Journal Of Psychiatric Research 2023, 161: 213-217. PMID: 36934603, DOI: 10.1016/j.jpsychires.2023.02.026.Peer-Reviewed Original ResearchConceptsChronic patientsSynaptic pruningStage of illnessEarly course patientsEarly course schizophreniaSeverity of delusionsWidespread reductionMajor disease mechanismsSynaptic deficitsSynaptic markersSynaptic eliminationPET scansFormal onsetBrain regionsSignificant positive correlationPatientsSchizophrenia studiesSchizophreniaDisease mechanismsCognitive performanceIllnessEarly phaseSpecific bindingPresent studyPositive correlationCharacteristics of trichotillomania and excoriation disorder across the lifespan
Lin A, Farhat L, Flores J, Levine J, Fernandez T, Bloch M, Olfson E. Characteristics of trichotillomania and excoriation disorder across the lifespan. Psychiatry Research 2023, 322: 115120. PMID: 36842397, PMCID: PMC10023474, DOI: 10.1016/j.psychres.2023.115120.Peer-Reviewed Original ResearchConceptsExcoriation disorderClinical characteristicsSkin-picking severityAttention-deficit/hyperactivity disorderCo-occurring conditionsBody-focused repetitive behaviorsObsessive-compulsive disorderSeverity scoreCurrent symptomsSignificant positive correlationTrichotillomaniaHyperactivity disorderDisordersSelf-reported anxietyAge 4High rateSubtypesSelf-report measuresSeverityCross-sectional survey responsesRepetitive behaviorsAdulthoodPositive correlation
2022
Scale-Free Functional Brain Networks Exhibit Increased Connectivity, Are More Integrated and Less Segregated in Patients with Parkinson’s Disease following Dopaminergic Treatment
Stylianou O, Kaposzta Z, Czoch A, Stefanovski L, Yabluchanskiy A, Racz F, Ritter P, Eke A, Mukli P. Scale-Free Functional Brain Networks Exhibit Increased Connectivity, Are More Integrated and Less Segregated in Patients with Parkinson’s Disease following Dopaminergic Treatment. Fractal And Fractional 2022, 6: 737. PMID: 38106971, PMCID: PMC10723163, DOI: 10.3390/fractalfract6120737.Peer-Reviewed Original ResearchHealthy control individualsMini-Mental State ExaminationDopaminergic treatmentParkinson's diseaseFunctional connectivityMental State ExaminationStandard therapyPD patientsPD populationHC groupState ExaminationFunctional brain networksControl individualsPharmacological studiesSignificant positive correlationDiseaseBrain networksPatientsCognitive performanceAdult Reading TestPositive correlationTreatmentLong-term memoryTherapyA positive correlation of leadership, faculty, and fellow gender and racial diversity in US academic hand surgery
Hui-Chou H, Wo L, Plana N, Smith K, Lin I. A positive correlation of leadership, faculty, and fellow gender and racial diversity in US academic hand surgery. Orthoplastic Surgery 2022, 10: 21-27. DOI: 10.1016/j.orthop.2022.09.001.Peer-Reviewed Original ResearchAmerican Association for Hand SurgeryHand surgeryHand fellowship programsAmerican Society for SurgerySociety for SurgerySurgeryFellowship traineesWhite raceRacial distributionFellowship programsRacial disparitiesMedical schoolsAcademic surgeryAcademic medicinePositive correlationResearch websiteTraining detailsGender disparitiesHigher academic rankRacial minoritiesFaculty cohortDisparitiesGenderFellowCohortCumulative risk exposure and child cellular aging in a Dutch low‐risk community sample
Beijers R, Thije I, Bolhuis E, O'Donnell K, Tollenaar M, Shalev I, Hastings W, MacIsaac J, Lin D, Meaney M, Kobor M, Belsky J, de Weerth C. Cumulative risk exposure and child cellular aging in a Dutch low‐risk community sample. Psychophysiology 2022, 60: e14205. PMID: 36323627, DOI: 10.1111/psyp.14205.Peer-Reviewed Original ResearchConceptsChildhood risk exposuresLow-risk community sampleAge 6Cortisol reactivityAge 10Cumulative risk exposureCommunity sampleCellular agingPhysical health outcomesHealth outcomesStressor exposureTelomere lengthSecondary findingsLater lifeChild cortisol reactivityRegression analysisSignificant main effectFurther investigationExposurePositive correlationMore researchStrong conclusionsAgingBiomarkersRisk Factors of Skilled Nursing Facility Admissions and the Interrelation With Hospitalization and Amount of Informal Caregiving Received
Cao Y, Allore H, Gutman R, Vander Wyk B, Jørgensen TSH. Risk Factors of Skilled Nursing Facility Admissions and the Interrelation With Hospitalization and Amount of Informal Caregiving Received. Medical Care 2022, 60: 294-301. PMID: 35149662, PMCID: PMC8916995, DOI: 10.1097/mlr.0000000000001697.Peer-Reviewed Original ResearchConceptsSkilled nursing facility admissionsNursing facility admissionsNumber of hospitalizationsSNF admissionImportant risk factorRisk factorsHospital admissionFacility admissionNon-Hispanic white race/ethnicityWhite race/ethnicityInformal caregivingWeak positive correlationDaily living (ADL) disabilityPossible risk factorsPositive correlationAging Trends StudyRace/ethnicityObservational followStrong positive correlationNational HealthAdmissionDementia diagnosisHospitalizationAlzheimer's diseaseHealth factors
2021
METTL3-mediated m6A RNA methylation promotes the anti-tumour immunity of natural killer cells
Song H, Song J, Cheng M, Zheng M, Wang T, Tian S, Flavell RA, Zhu S, Li HB, Ding C, Wei H, Sun R, Peng H, Tian Z. METTL3-mediated m6A RNA methylation promotes the anti-tumour immunity of natural killer cells. Nature Communications 2021, 12: 5522. PMID: 34535671, PMCID: PMC8448775, DOI: 10.1038/s41467-021-25803-0.Peer-Reviewed Original ResearchMeSH KeywordsAdenosineAnimalsCarcinogenesisCell Line, TumorGene DeletionHomeostasisInterleukin-15Killer Cells, NaturalLymphocytes, Tumor-InfiltratingMethylationMethyltransferasesMice, Inbred C57BLMice, KnockoutNeoplasmsProtein Tyrosine Phosphatase, Non-Receptor Type 11Proto-Oncogene Proteins c-aktRNASignal TransductionTumor MicroenvironmentConceptsAnti-tumor immunityNK cellsTumor-infiltrating NK cellsNK cell infiltrationNatural killer cellsAccelerated tumor developmentExert critical rolesImmunosurveillance functionKiller cellsIL-15Cell infiltrationTumor microenvironmentTumor developmentProtein expressionSuppressed activationM6A RNA methylationEffector moleculesExpression levelsMETTL3Cells altersImmunityM6A methylationCellsPositive correlationHomeostasisHousehold Food Expenditure Share During Pregnancy: Evidence From Rural Sri Lanka
Gunarathne S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Household Food Expenditure Share During Pregnancy: Evidence From Rural Sri Lanka. Current Developments In Nutrition 2021, 5: 753. PMCID: PMC8181375, DOI: 10.1093/cdn/nzab046_050.Peer-Reviewed Original ResearchPregnant womenHousehold food expenditureMean monthly household incomeRural pregnant womenIncome quintileSelf-administered questionnaireMonthly household incomeHousehold incomeProspective cohortPregnancy cohortMean ageHighest quintilePositive correlationTrimesterPregnancyRural Sri LankaSignificant positive correlationWeak positive correlationQuintileMeasures ANOVAOne-way ANOVASignificant differencesCohort
2020
Association Between Entrustable Professional Activities and Milestones Evaluations: Real-time Assessments Correlate With Semiannual Reviews
Albright JB, Meier AH, Ruangvoravat L, VanderMeer TJ. Association Between Entrustable Professional Activities and Milestones Evaluations: Real-time Assessments Correlate With Semiannual Reviews. Journal Of Surgical Education 2020, 77: e220-e228. PMID: 32747323, DOI: 10.1016/j.jsurg.2020.07.027.Peer-Reviewed Original ResearchConceptsSignificant positive correlationSUNY Upstate Medical UniversityMilestone scoresGall bladder diseaseUniversity-based hospitalEntrustable professional activitiesSurgical residentsUpstate Medical UniversityPositive correlationGeneral surgery residentsBiannual evaluationBladder diseaseMedical UniversityACGME milestonesSpearman rank correlationPilot studySurgery residentsMilestone evaluationsSignificant correlationSurgeryEPA evaluationScoresAmerican BoardResident progressionSemiannual reviews
2019
Appraisal of Headache Trigger Patterns Using Calendars
Turner DP, Leffert LR, Houle TT. Appraisal of Headache Trigger Patterns Using Calendars. Headache The Journal Of Head And Face Pain 2019, 60: 370-381. PMID: 31784989, PMCID: PMC7077923, DOI: 10.1111/head.13703.Peer-Reviewed Original ResearchConceptsPatterns of triggersHigher participant ratingsAbility of individualsLaboratory tasksParticipants' ratingsHeadache activityDaily diariesPrevious beliefRatingsNegative associationLow correlationTrigger patternsBeliefsParticipantsIndividualsHeadache calendarExperimental triggersJudgmentsTaskHigh positive correlationDegree of associationRelationshipAppraisalAssociationPositive correlationEffects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study
Tuisku J, Plavén-Sigray P, Gaiser EC, Airas L, Al-Abdulrasul H, Brück A, Carson RE, Chen MK, Cosgrove KP, Ekblad L, Esterlis I, Farde L, Forsberg A, Halldin C, Helin S, Kosek E, Lekander M, Lindgren N, Marjamäki P, Rissanen E, Sucksdorff M, Varrone A, Collste K, Gallezot J, Hillmer A, Huang Y, Höglund C, Johansson J, Jucaite A, Lampa J, Nabulsi N, Pittman B, Sandiego C, Stenkrona P, Rinne J, Matuskey D, Cervenka S. Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study. European Journal Of Nuclear Medicine And Molecular Imaging 2019, 46: 2329-2338. PMID: 31363804, PMCID: PMC6717599, DOI: 10.1007/s00259-019-04403-7.Peer-Reviewed Original ResearchConceptsBody mass indexPositron emission tomographyEffect of ageMultilinear analysis 1PET centersGlobal gray matterMass indexSubgroup analysisClinical studiesTSPO levelsHealthy subjectsTurku PET CentreHealthy volunteersPositive correlationTemporal cortexTSPO genotypeIndividual biological propertiesMale subjectsPurposeThe purposeConclusionThese findingsLinear mixed effects modelsGray matterParietal cortexSignificant negative correlationEmission tomographyAcute physical exercise increases APPL1/PI3K signaling in the hypothalamus of lean mice
Gaspar R, Muñoz V, Kuga G, Nakandakari S, Crisol B, Lenhare L, Breda L, Botezelli J, Sant'Ana M, da Silva A, Cintra D, de Moura L, Ropelle E, Pauli J. Acute physical exercise increases APPL1/PI3K signaling in the hypothalamus of lean mice. European Journal Of Neuroscience 2019, 50: 3181-3190. PMID: 31206806, DOI: 10.1111/ejn.14490.Peer-Reviewed Original ResearchConceptsLean miceExercise sessionsPhysical exerciseAcute exercise sessionAcute physical exercisePhysical exercise sessionPI3K p110PI3K mRNAAdiponectin pathwayArcuate nucleusSwiss miceHypothalamusAdiponectinEnergy homeostasisMiceMRNA levelsPI3KFood consumptionLeucine zipper motif 1BXD miceExerciseK mRNAPresent studyPositive correlationKey proteinsComparison of the Standardized Video Interview and Interview Assessments of Professionalism and Interpersonal Communication Skills in Emergency Medicine
Hopson L, Dorfsman M, Branzetti J, Gisondi M, Hart D, Jordan J, Cranford J, Williams S, Regan L. Comparison of the Standardized Video Interview and Interview Assessments of Professionalism and Interpersonal Communication Skills in Emergency Medicine. AEM Education And Training 2019, 3: 259-268. PMID: 31360819, PMCID: PMC6637001, DOI: 10.1002/aet2.10346.Peer-Reviewed Original ResearchInterpersonal communication skillsEmergency medicineInterview assessmentAssessment of professionalismRank order list positionSVI scoresRank order listsEM residency programsIndependent-groups t-testKnowledge of professionalsOne-way analysis of variancePotential influence of genderGender differencesStandardized Video InterviewOne-way analysisResidency programsProfessionalsNo group differencesObservational studyStandardized instrumentsPositive correlationCommunication skillsSecondary objectivesIndependent-groupsAnalysis of varianceNeural correlates of chemotherapy-induced emotion regulation impairment in breast cancer patients.
Gan C, Lv Y, Zhao J, Chao HH, Li CR, Zhang C, Yu F, Cheng H. Neural correlates of chemotherapy-induced emotion regulation impairment in breast cancer patients. American Journal Of Cancer Research 2019, 9: 171-179. PMID: 30755820, PMCID: PMC6356929.Peer-Reviewed Original Research
2018
Temporal and spatial associations between influenza and asthma hospitalisations in New York City from 2002 to 2012: a longitudinal ecological study
Trinh P, Jung TH, Keene D, Demmer RT, Perzanowski M, Lovasi G. Temporal and spatial associations between influenza and asthma hospitalisations in New York City from 2002 to 2012: a longitudinal ecological study. BMJ Open 2018, 8: e020362. PMID: 30269061, PMCID: PMC6169763, DOI: 10.1136/bmjopen-2017-020362.Peer-Reviewed Original ResearchConceptsInfluenza hospitalisationsAsthma hospitalisationsExcess riskLongitudinal ecological studyAge groupsClinical Modification diagnosis codesSignificant positive correlationInfluenza prevention strategiesSignificant correlationDifferent age groupsNinth RevisionDiagnosis codesPrimary diagnosisAdults 18HospitalisationStatewide PlanningPositive correlationInternational ClassificationIndividuals 18Prevention strategiesRisk percentageAdult populationOverall populationAsthmaInfluenza
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