2025
Smoking Status of the US Cancer Population and a New Perspective From the National Cancer Database
Caturegli G, Zhu X, Palis B, Mullett T, Resio B, Boffa D. Smoking Status of the US Cancer Population and a New Perspective From the National Cancer Database. JAMA Oncology 2025, 11: 564-566. PMID: 40146125, PMCID: PMC11950973, DOI: 10.1001/jamaoncol.2025.0247.Peer-Reviewed Original ResearchIntegrating epidemiology and genomics data to estimate the prevalence of acquired cysteine drug targets in the U.S. cancer patient population
Arun A, Liarakos D, Mendiratta G, Kim J, Goshua G, Olson P, Stites E. Integrating epidemiology and genomics data to estimate the prevalence of acquired cysteine drug targets in the U.S. cancer patient population. The Pharmacogenomics Journal 2025, 25: 5. PMID: 40044654, DOI: 10.1038/s41397-025-00364-3.Peer-Reviewed Original ResearchConceptsGenomic dataEstimates of mutation ratesSomatic missense mutationsGenomic informationPopulation-level estimatesCancer patient populationMissense mutationsNon-epidemiologicallyCancer patientsMutation ratePathogenic mutationsCysteine residuesCancer epidemiologyMutation-specificMutation abundanceDrug targetsMutationsIntegrates epidemiologyAbundancePatient populationEpidemiologyGenomePopulationTargeted therapyResiduesTuberculosis and people who use drugs: why focus on this overlooked population is important and why adapted interventions are necessary
D'Ottavi M, Godfrey-Faussett P, Merle C, Sofonea M, Laureillard D, Vickerman P, Molès J, Altice F, Van de Perre P, Stone J, Nagot N. Tuberculosis and people who use drugs: why focus on this overlooked population is important and why adapted interventions are necessary. The Lancet Global Health 2025, 13: e593-e598. PMID: 39862874, DOI: 10.1016/s2214-109x(24)00481-9.Peer-Reviewed Original ResearchConceptsReduce health inequalitiesCommunity-based approachActive case findingNational Tuberculosis ProgrammeHealth inequalitiesTargeted interventionsTuberculosis interventionsCase findingTreatment adherenceGeneral populationTuberculosis ProgrammeMarginalised populationsHIV fieldInterventionPrevalence of tuberculosisTuberculosis burdenPopulation levelTuberculosis transmissionHigher incidencePeoplePopulationAdherenceHIVPrevalenceLinkageAddressing selection bias in cluster randomized experiments via weighting
Papadogeorgou G, Liu B, Li F, Li F. Addressing selection bias in cluster randomized experiments via weighting. Biometrics 2025, 81: ujaf013. PMID: 40052595, DOI: 10.1093/biomtc/ujaf013.Peer-Reviewed Original ResearchConceptsCluster-randomized experimentCluster randomized trialAverage treatment effectSelection biasInverse probability weightingOverall populationTreatment effectsCo-paymentControl armRecruited populationProbability weightingRandomized experimentRandomized trialsPopulationEstimation strategyTreatment assignmentIndividualsRecruitment assumptionR packageOverallAnalysis approachInterventionRecruitmentAssociation between methyl-CpG-binding domain protein 5 gene and depressive symptoms in Mexican population: Results from MxGDAR/Encodat cohort.
Sanabrais-Jiménez M, Camarena B, Aguilar-García A, Genis-Mendoza A, Martínez-Magaña J, Nicolini H, Villatoro-Velá J, Bustos-Gamiño M, Gutiérrez-López M, Medina-Mora M. Association between methyl-CpG-binding domain protein 5 gene and depressive symptoms in Mexican population: Results from MxGDAR/Encodat cohort. Brazilian Journal Of Psychiatry 2025 PMID: 39787278, DOI: 10.47626/1516-4446-2024-3859.Peer-Reviewed Original ResearchDepressive symptomsAnxiety symptomsGenetic principal componentsMexican populationScreening questionnaireDepressive symptomatologyMexican cohortLogistic regression approachHealthy controlsAddiction researchDevelopment of DSDI padAnxietyCohortAssociationSymptomsMBD5Gene silencingGenesPopulationQuestionnairePLINKMYO1HSymptomatologySex
2024
Evaluation of imputation performance of multiple reference panels in a Pakistani population
Xu J, Liu D, Hassan A, Genovese G, Cote A, Fennessy B, Cheng E, Charney A, Knowles J, Ayub M, Peterson R, Bigdeli T, Huckins L. Evaluation of imputation performance of multiple reference panels in a Pakistani population. Human Genetics And Genomics Advances 2024, 6: 100395. PMID: 39696820, PMCID: PMC11759560, DOI: 10.1016/j.xhgg.2024.100395.Peer-Reviewed Original ResearchGenome-wide association studiesReference panelImputation accuracyMultiple reference panelsPakistani individualsGenotype imputationAssociation studiesGenotype dataAncestry compositionEuropean individualsSample sizeTOPMedDiverse populationsPakistani populationImputationGenomeAncestryIndividualsGenotypesPopulationVariantsFuture panelsRacial and ethnic disparities in alcohol-associated liver disease hospitalizations in Brazil before and after the COVID-19 pandemic
Heringer D, Costa G, Weleff J, Rodrigues V, Sengupta S, Anand A. Racial and ethnic disparities in alcohol-associated liver disease hospitalizations in Brazil before and after the COVID-19 pandemic. Annals Of Hepatology 2024, 30: 101742. PMID: 39653118, DOI: 10.1016/j.aohep.2024.101742.Peer-Reviewed Original ResearchMonthly hospitalization ratesHospitalization ratesAlcohol-associated liver diseaseHealth-related inequalitiesInterrupted time series analysisIncidence of alcohol‐associated liver diseaseAge of hospitalized patientsPre-pandemic ratesEthnic groupsCOVID-19 pandemicEthnic disparitiesPublic hospitalsStatistically significant decreaseImpact of raceBlack populationHospitalLiver diseaseStudy periodCOVID-19Total populationSignificant decreaseCombined populationWhole populationConsecutive monthsPopulationPotential use of epigenetic clocks to understand factors associated with aging at the population level and in public health
Martínez-Magaña J, Hurtado-Soriano J, Montalvo-Ortiz J, Gomez-Verjan J. Potential use of epigenetic clocks to understand factors associated with aging at the population level and in public health. Gaceta Médica De México 2024, 160: 357-359. PMID: 39602607, DOI: 10.24875/gmm.m24000897.Peer-Reviewed Original ResearchThe association of hidradenitis suppurativa with cigarette smoking and cannabis use: a cross-sectional study in the All of Us Research Program
Chen G, Shipman W, Hodelin C, Hsia H, Cohen J, Eisenstein A. The association of hidradenitis suppurativa with cigarette smoking and cannabis use: a cross-sectional study in the All of Us Research Program. Clinical And Experimental Dermatology 2024, 50: 1042-1044. PMID: 39573984, PMCID: PMC12020478, DOI: 10.1093/ced/llae521.Peer-Reviewed Original ResearchCigarette smokingOdds of cigarette smokingElectronic health recordsHealth research programsCannabis useCross-sectional studyCross sectional studyHealth recordsSectional studySmokingHidradenitis suppurativaNational InstituteSurvey dataAssociationCannabisOddsUseCigaretteHidradenitisResearch programNationalProgramPopulationStudyApplying Concepts of Successful Aging in Measuring and Promoting Whole Person Health
Tsai J, Jones A. Applying Concepts of Successful Aging in Measuring and Promoting Whole Person Health. Medical Care 2024, 62: s21-s23. PMID: 39514489, PMCID: PMC11548807, DOI: 10.1097/mlr.0000000000002040.Peer-Reviewed Original ResearchConceptsWhole-person healthPersonal healthLife course perspectiveTransform healthcare systemsAdult populationWell-beingAging adult populationUS veteran populationAge-friendly practicesPopulation at-riskPublic health concernPoor healthAbsence of diseaseHealthcare systemVeteran populationSuccessful agingAging adultsAge-FriendlyHealthCourse perspectiveHealth concernReview studiesAgePopulationMultiple indicatorsCorporate activities that influence population health: a scoping review and qualitative synthesis to develop the HEALTH-CORP typology
Burgess R, Nyhan K, Freudenberg N, Ransome Y. Corporate activities that influence population health: a scoping review and qualitative synthesis to develop the HEALTH-CORP typology. Globalization And Health 2024, 20: 77. PMID: 39516852, PMCID: PMC11549802, DOI: 10.1186/s12992-024-01082-4.Peer-Reviewed Original ResearchConceptsInfluence population healthPopulation healthHealth equityPopulation groupsMiddle-income countriesHealth inequalitiesHealth outcomesScoping reviewCommercial determinantsInfluence healthCorporate activitiesQualitative synthesisHealthHealth impactsCorporate practicesLack of researchCorporate influenceSurveillance effortsPolicy makersPopulationPracticeCode descriptionEmployment practicesIntroductionThe conceptCivil society actorsField Notes from the Border: Lessons Learned in Conducting Mental Health Research Involving Newly Arrived Latinx Immigrants as Study Participants
Vargas L, Ariefdjohan M, Page C, Meisel Z, Ulrich C, Alegría M, Pimentel N, Epperson C, Richmond T. Field Notes from the Border: Lessons Learned in Conducting Mental Health Research Involving Newly Arrived Latinx Immigrants as Study Participants. Journal Of Immigrant And Minority Health 2024, 27: 181-189. PMID: 39503832, PMCID: PMC11781956, DOI: 10.1007/s10903-024-01643-0.Peer-Reviewed Original ResearchPublic health researchLatinx immigrantsImmigrant populationHealth researchCommunity partnersParticipant consentStudy participantsVulnerable populationsData collection proceduresStudy populationField notesResearch protocolParticipantsUnique issuesBest practicesCultural fluencyEthical considerationsCollection proceduresUS southern borderPopulationLatinxUnique perspectiveBurden of non-communicable diseases due to population ageing in China: challenges to healthcare delivery and long term care services
Lv Y, Fan L, Zhou J, Ding E, Shen J, Tang S, He Y, Shi X. Burden of non-communicable diseases due to population ageing in China: challenges to healthcare delivery and long term care services. The BMJ 2024, 387: e076529. PMID: 39424307, PMCID: PMC11484826, DOI: 10.1136/bmj-2023-076529.Peer-Reviewed Original ResearchDeveloping personas to inform the design of digital interventions for perinatal mental health
Zimmermann M, Yonkers K, Tabb K, Schaefer A, Peacock-Chambers E, Clare C, Boudreaux E, Lemon S, Byatt N, Tulu B. Developing personas to inform the design of digital interventions for perinatal mental health. JAMIA Open 2024, 7: ooae112. PMID: 39494447, PMCID: PMC11528508, DOI: 10.1093/jamiaopen/ooae112.Peer-Reviewed Original ResearchDigital mental health interventionsPerinatal populationDigital interventionsPerinatal mental health conditionsPerinatal mental healthMental health careMental health interventionsDesign of digital interventionsMental health conditionsMental health concernsUser-centered designHealth interventionsHealth careMental healthSensitive interventionsHealth conditionsParticipant interviewsHealth concernInterventionPerinatal individualsAnxietyQualitative analysisPotential user groupsPopulationUser engagementCause-Specific Mortality Rates Among the US Black Population
Arun A, Caraballo C, Sawano M, Lu Y, Khera R, Yancy C, Krumholz H. Cause-Specific Mortality Rates Among the US Black Population. JAMA Network Open 2024, 7: e2436402. PMID: 39348122, PMCID: PMC11443349, DOI: 10.1001/jamanetworkopen.2024.36402.Commentaries, Editorials and LettersThe Recovery of Consciousness via Evidence-Based Medicine and Research (RECOVER) Program
Fischer D, Abella B, Bass G, Charles J, Hampton S, Kulick-Soper C, Mendlik M, Mitchell O, Narva A, Pino W, Sikandar M, Sinha S, Waldman G, Ware J, Levine J. The Recovery of Consciousness via Evidence-Based Medicine and Research (RECOVER) Program. Neurology Clinical Practice 2024, 14: e200351. PMID: 39185092, PMCID: PMC11341005, DOI: 10.1212/cpj.0000000000200351.Peer-Reviewed Original ResearchEvidence-based medicineVulnerable patient populationAvoidable mortalityLongitudinal careSevere acute brain injuryCarePatient populationBrain injuryNeuroprognosticationRecovery of consciousnessClinical approachProgramRecovering programProvidersSubspecialtyEvolving literatureGuidelinesEducationMortalityMedicineMorbidityAcute brain injuryInjuryPopulationPracticeThe evolution of selection bias in the recent epidemiologic literature—a selective overview
Lu H, Howe C, Zivich P, Gonsalves G, Westreich D. The evolution of selection bias in the recent epidemiologic literature—a selective overview. American Journal Of Epidemiology 2024, 194: 580-584. PMID: 39136207, PMCID: PMC11879605, DOI: 10.1093/aje/kwae282.Peer-Reviewed Original ResearchThe Association Between State-Level Prenatal Substance Use Policies and Rates of Maternal Mortality in the United States: A Legal Epidemiology Study.
Thomas K, Struble C, Stenersen M, Moore K. The Association Between State-Level Prenatal Substance Use Policies and Rates of Maternal Mortality in the United States: A Legal Epidemiology Study. The Journal Of Law, Medicine & Ethics 2024, 52: 75-80. PMID: 38995261, DOI: 10.1017/jme.2024.67.Peer-Reviewed Original ResearchSignal integration and adaptive sensory diversity tuning in Escherichia coli chemotaxis
Moore J, Kamino K, Kottou R, Shimizu T, Emonet T. Signal integration and adaptive sensory diversity tuning in Escherichia coli chemotaxis. Cell Systems 2024, 15: 628-638.e8. PMID: 38981486, PMCID: PMC11307269, DOI: 10.1016/j.cels.2024.06.003.Peer-Reviewed Original ResearchEscherichia coli chemotaxisPopulation of E. coliMeasure kinase activityPhenotypic diversitySensory diversityDecreased diversityKinase activityDiverse phenotypesChemical signalsDiversitySingle cellsResponse to changesCellsSignalPhenotypePopulationChemotaxisSignal integrityLigandCompetitive ligandChemoattractantImproving prediction of linear regression models by integrating external information from heterogeneous populations: James–Stein estimators
Han P, Li H, Park S, Mukherjee B, Taylor J. Improving prediction of linear regression models by integrating external information from heterogeneous populations: James–Stein estimators. Biometrics 2024, 80: ujae072. PMID: 39101548, PMCID: PMC11299067, DOI: 10.1093/biomtc/ujae072.Peer-Reviewed Original ResearchConceptsJames-Stein estimatorLinear regression modelsIndividual-level dataComprehensive simulation studyRegression modelsNumerical performanceSimulation studyShrinkage methodCoefficient estimatesPredictive meanReduced modelStudy population heterogeneityInternal modelEstimationStudy populationBlood lead levelsInternational studiesCovariatesPatella bonePublished literatureLead levelsExternal studiesSummary informationPopulationSubsets
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